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Sky-Watcher EQ6-R Pro Equatorial Mount

Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.

New treatment targets found for blinding retinal disease

Scientists have identified new points to calm frenzied energy production in the retina, enabling recovery. The excessive byproducts of glycolysis initiate a vicious loop of crosstalk between endothelial cells and microglia, promoting inflammation and dysfunctional blood vessels.

Your brain parasite isn't making you sick -- here's why

Researchers at UVA School of Medicine discovered that brain defenders called microglia release a unique immune molecule to control the parasite in the brain, preventing symptomatic toxoplasmosis. This finding has implications for brain infections, neurodegenerative diseases and autoimmune disorders.

New role for white blood cells in the developing brain

Researchers discovered brain-resident immune cells that play a crucial role in normal brain development and are essential for the regulation of brain functions. The findings suggest a connection between gut bacteria, white blood cells, and neurological diseases.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Autism in males linked to defect in brain immune cells, microglia

A new study suggests that impairments in microglia play a key role in the development of autism behaviors in some cases. The researchers found that protein overproduction in microglial cells leads to impaired synapse-pruning function, resulting in ASD-like social behavior deficits, primarily in males.

A new way to study HIV's impact on the brain

Researchers created a laboratory model of three types of brain cells to study HIV's impact on the central nervous system. The model revealed that HIV infection can take a toll on the brain, causing inflammation and damage. Antiretroviral therapy (ART) can reduce inflammation by around 70%, but also triggers its own unique response.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Alzheimer risk genes converge on microglia

A study reveals that Alzheimer risk genes are linked to microglia's response to amyloid-beta, a key protein in the disease. The researchers identified 11 new risk genes that are upregulated when facing increased amyloid-beta levels.

Alzheimer's disease: Inflammation triggers fatal cycle

Researchers discovered that an immune reaction in the brain adds fuel to the fire of inflammation, leading to the development of Alzheimer's disease. The microglia cells' activation of inflammasomes makes degradation of Aß proteins more difficult, creating a devastating process.

Immune cells against Alzheimer's?

Scientists have identified a specific antibody that binds to brain immune cells and triggers processes that enhance microglia activity. This stimulates the immune cells to detect and degrade abnormal protein deposits, known as plaques, more effectively, potentially providing better protection against Alzheimer's disease.

Brain cells' immune receptors and depression

Researchers found a polymorphism associated with protective effects against major depressive disorder in women. Microglial cells' immune receptors may play a role in neuropsychiatric disorders.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Treatment to reset immune cells markedly improves TBI symptoms

A preclinical study suggests that targeting overactive immune cells in the brain can limit brain cell loss and reverse cognitive and motor difficulties caused by traumatic brain injury (TBI). Mice treated with an experimental drug recovered markedly better than control mice, showing less tissue loss and improved motor and cognitive per...

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Microglia regulate forgetting in the adult brain

A recent study has shown that microglia regulate forgetting in the adult brain by weakening and eliminating synapses connecting engram neurons. Inhibiting microglial activity or depleting them prevents forgetting, while intact microglia facilitate the dissociation of engram cells, leading to memory erasure.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Radiation breaks connections in the brain

Researchers found that radiation triggers an immune response that severs connections between nerve cells, leading to damage and cognitive problems. The study suggests two potential approaches to prevent this damage: blocking a receptor responsible for synapse removal or tamping down the brain's immune response.

Immune 'control switch' could prevent brain injury in premature babies

A team of international researchers has identified a potential treatment for reducing brain injury in premature babies by targeting hyperactive microglia with a drug that activates the Wnt signalling pathway. This approach may help protect white matter and prevent long-term memory problems associated with preterm birth.

GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Changes in microglia impact neuroinflammation and disease pathology

Researchers have made significant breakthroughs in understanding the role of microglia in neuroinflammation, a hallmark of degenerative brain diseases such as Alzheimer's Disease. Studies show that changes in microglial cells can trigger hyperexcitability in the brain, leading to decreased sociability and motivation.

Study suggests a new way to think about the brain's link to postpartum depression

Research in animals shows that chronic stress during pregnancy triggers an immune response in the brain, leading to potential changes in brain functions. The study found that stressed rats showed evidence of neuroinflammation and increased activity levels of microglia, suggesting a link between gestational stress and postpartum depress...

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

New findings about mechanisms regulating brain inflammation

A recent study has identified a key regulator of microglia function during inflammation, which could become a significant component in treating neurodegenerative diseases. TET2 protein modulates the immune response generated by microglia cells in the brain under inflammatory conditions.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Research discoveries suggest that LH dipeptide improves mental health

Researchers discovered LH dipeptide as a potent anti-inflammatory agent that inhibits the secretion of inflammatory cytokines from microglia, reducing brain inflammation and depression symptoms. Consuming foods rich in LH dipeptide may be a safe method for maintaining good mental health.

High-fat diets affect your brain, not just your physical appearance

A recent Yale study found that high-fat diets stimulate hypothalamic inflammation, leading to changes in microglial cells and regulating energy homeostasis. The research suggests a neurological mechanism controlling food intake, with potential implications for obesity and diseases like Alzheimer's.

A protective factor against Alzheimer's disease?

Researchers discovered that higher levels of TREM2 protein in cerebrospinal fluid are associated with improved prognosis and reduced cognitive decline in Alzheimer's patients. The study suggests that TREM2 may play a key role in regulating the brain's protective immune response, offering new therapeutic strategies.

Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Microglia turned on

Researchers have developed a microglia-selective fluorogenic probe that triggers fluorescence through gene expression, enabling selective labeling and imaging of microglia cells in live brain tissue. This probe has the potential to detect developing neural diseases such as Alzheimer's disease and stroke.

Why visual stimulation may work against Alzheimer's

Researchers found that visual stimulation can prevent neuron degeneration and enhance synaptic function in Alzheimer's disease models. The treatment also improved spatial memory performance in older mice without a predisposition for the disease.

New chemical probe for visualizing brain immune cells

Researchers developed a chemical probe that enables live-imaging of microglia in the brain, crucial for understanding brain development and disease. The probe, CDr20, labels microglia in both human- and primate-derived cells, allowing for clinical-relevant studies.

Do 'microglia' hold the key to stop Alzheimer's disease?

Researchers studied how microglia cells in the brain respond to toxic proteins associated with Alzheimer's disease. The study found that age, sex, and genetics affect microglial response, suggesting that modulating this response could lead to new treatments.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Retinal prion disease study redefines role for brain cells

Scientists discovered that microglia, a type of nervous system cell suspected to cause retinal damage, surprisingly had no damaging role during prion disease in mice. Microglia might delay disease progression, providing new insights into inherited photoreceptor degeneration diseases.

Scientists create new map of brain's immune system

Researchers created a high-resolution map of the brain's immune system, showing that all microglia have the same core signature but adapt differently depending on their function. This discovery is significant for understanding brain diseases like multiple sclerosis and Alzheimer's.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Faulty molecular master switch may contribute to AMD

Researchers at the National Eye Institute discovered that TGF-beta signaling governs immune cell function in the eye, leading to activated microglia and retina damage. Disrupting this signal may represent a potential therapeutic target for treating AMD.

Essential nutrient may help fight Alzheimer's across generations

Researchers at Arizona State University discover that choline supplementation may help fight Alzheimer's disease in mice and their offspring. The study reveals that high choline intake during gestation and lactation improves spatial memory in subsequent generations, suggesting a transgenerational effect.

Microglia transmit pain to the brain during stress

Research found that activation of microglia in the spinal cord is responsible for increased pain sensitivity in response to stress. Eliminating microglia from the spinal cord prevented these effects, highlighting their role in transmitting pain to the brain.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Classifying brain microglia: Which are good and which are bad?

Researchers have identified nine distinct groups of microglia, including some that appear only in embryonic or newborn stages, and others that are involved in myelination. These findings may help uncover new roles for microglia in disease and development, and could lead to the development of therapies targeting specific subpopulations.

Microglia react distinctively during inflammation

Researchers from the Luxembourg Institute of Health uncover distinct microglial signatures in response to acute inflammation, highlighting potential benefits for resolving inflammation. Their single-cell transcriptomic study provides new resources for understanding brain disorders and developing novel therapeutic strategies.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.