Articles tagged with Olfactory Receptors
Olfactory sensory neurons can adapt to odorant stimulation, but the ability to enhance long-term survival after stimulation has been unclear. Researchers found that odorants stimulate the Erk/MAP kinase/CREB pathway, leading to cell survival and dynamic long-term adjustment to sensory information.
Researchers refute vibration theory by finding shape of odor molecules crucial for distinct smells. The study's results support the prevailing 'shape theory', which suggests that chemical shape is the primary factor in determining a substance's scent.
Researchers successfully cloned mice from olfactory cell nuclei, demonstrating totipotent development and normal brain function. The study expands understanding of neuronal diversity and offers insights into reprogramming mature cells.
Scientists at Vanderbilt University have verified that female Anopheles mosquitoes contain receptors responding to one of the chemical compounds found in human sweat. This discovery may lead to better ways to repel deadly insects and uncover additional chemicals that either attract or repel them.
Researchers discovered that human sperm cells have a receptor for chemo-attraction, which triggers movement towards elevated concentrations of a sperm-attracting substance called bourgeonal. This finding suggests that sperm may be able to 'smell' their way to the egg.
A study found that 54% of human olfactory receptor genes are impaired, compared to 28-36% in other primates. The decline of the sense of smell likely occurred within an 'evolutionary moment' 3-5 million years ago.
Scientists propose a new mechanism for passing information through cell membranes via a shuttlecock motion involving metalloproteins. This theory explains why dietary zinc deficiencies lead to a loss of smell and has significant implications for understanding the sense of smell.
Researchers at UC Berkeley have found that the adult brain has more capabilities to change than previously thought. By exposing non-detectors to a specific odor, they showed that both nostrils can learn to detect it, suggesting a central component in the brain is involved in olfactory learning.
The Odor Index is a new tool that relates the concentration of odorants to human perception, providing a comparative scale for measuring odors. The technology has shown significant reductions in odors in wastewater treatment plants and other industries.
Researchers at Vanderbilt University have identified four genes in the Anopheles gambiae mosquito that code for odorant receptors similar to those found in fruit flies. These genes are only expressed in the antennae and maxillary palps, indicating that mosquitoes use a conserved chemosensory system to track human body odor.
Researchers have found that both smells and pheromones can arouse instinctive behaviors in mammals, including humans. This is achieved through the detection of odorants by the vomeronasal organ (VNO) and the olfactory epithelium (OE), with pheromone signals directly influencing mid-brain areas controlling behavior and hormonal responses.
A nerve protein known as the capsaicin receptor triggers pain signals when exposed to heat or noxious chemicals, contributing to pain from tissue injury and inflammation. Blocking this receptor may ease some kinds of pain, such as visceral pain conditions.
Scientists have identified a family of candidate genes in humans and mice that code for receptors detecting bitter and sweet tastes. The discovery provides new tools to trace the wiring of the taste perception pathways into the brain, shedding light on how we perceive different tastes.
Researchers have discovered that specialized proteins in the nose called olfactory receptors can bind with multiple odor molecules, creating a unique 'fingerprint' that the brain understands as a particular smell. This discovery could lead to new fragrances and flavors, as well as artificial smell sensors.
Scientists discover that the sense of smell in mammals uses a combinatorial code to recognize and process odors, allowing for the detection of thousands of scents with relatively few odor receptors. The study reveals that different combinations of receptors are used to describe various smells.
Linda Buck and colleagues found that the olfactory system uses a combination of odorant receptors to recognize different odors. The nose can discriminate a vast number of diverse odorants by recognizing distinct combinations of receptors.
Scientists have isolated two novel proteins expressed in cells specifically geared to the sense of taste, which are believed to be the first taste receptors. These candidate taste receptors resemble those that mediate sensory processes such as vision and olfaction and are positioned in specific cells on the tongue.
Researchers at Columbia University have linked a particular odor to the proteins in the human nose that detect it for the first time. They matched the smell of meat to a specific protein in rat nerve cells, shedding light on how the sense of smell works.
Researchers have identified a multigene family of candidate pheromone receptors expressed by sensory neurons in the vomeronasal organ, which may recognize different classes of pheromones. The discovery could lead to understanding of innate behaviors and mating behaviors in mice.