Researchers have found that both smells and pheromones can arouse instinctive behaviors in mammals, including humans. This is achieved through the detection of odorants by the vomeronasal organ (VNO) and the olfactory epithelium (OE), with pheromone signals directly influencing mid-brain areas controlling behavior and hormonal responses.
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A nerve protein known as the capsaicin receptor triggers pain signals when exposed to heat or noxious chemicals, contributing to pain from tissue injury and inflammation. Blocking this receptor may ease some kinds of pain, such as visceral pain conditions.
Scientists have identified a family of candidate genes in humans and mice that code for receptors detecting bitter and sweet tastes. The discovery provides new tools to trace the wiring of the taste perception pathways into the brain, shedding light on how we perceive different tastes.
Researchers have discovered that specialized proteins in the nose called olfactory receptors can bind with multiple odor molecules, creating a unique 'fingerprint' that the brain understands as a particular smell. This discovery could lead to new fragrances and flavors, as well as artificial smell sensors.
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Scientists discover that the sense of smell in mammals uses a combinatorial code to recognize and process odors, allowing for the detection of thousands of scents with relatively few odor receptors. The study reveals that different combinations of receptors are used to describe various smells.
Linda Buck and colleagues found that the olfactory system uses a combination of odorant receptors to recognize different odors. The nose can discriminate a vast number of diverse odorants by recognizing distinct combinations of receptors.
Scientists have isolated two novel proteins expressed in cells specifically geared to the sense of taste, which are believed to be the first taste receptors. These candidate taste receptors resemble those that mediate sensory processes such as vision and olfaction and are positioned in specific cells on the tongue.
Researchers at Columbia University have linked a particular odor to the proteins in the human nose that detect it for the first time. They matched the smell of meat to a specific protein in rat nerve cells, shedding light on how the sense of smell works.
Researchers have identified a multigene family of candidate pheromone receptors expressed by sensory neurons in the vomeronasal organ, which may recognize different classes of pheromones. The discovery could lead to understanding of innate behaviors and mating behaviors in mice.
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