Articles tagged with Airway Epithelium
Researchers at the University of Iowa have discovered that rare lung cells called pulmonary ionocytes mediate chloride and water absorption in airway surfaces. This unexpected function challenges previous assumptions about cystic fibrosis treatment.
A team of researchers developed a novel chip-based infection model to study invasive aspergillosis, a mold infection that affects the lungs. The model allows for live microscopic observation of damage caused by fungal hyphae and the response of immune cells.
A National Jewish Health-led study found that over a third of identified genetic risk factors for asthma are associated with altered function of airway epithelium. The research discovered genetic changes in genes related to mucus production and type 2 inflammatory pathways, increasing asthma risk.
Researchers found significant cancer-like gene expression changes in healthy smokers' large airway epithelia compared to nonsmokers. The study suggests smoking induces molecular alterations in the large airway epithelium prior to disease development, making it a primary site for lung cancer risk.