Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
The updated Berlin Definition of ARDS combines consensus discussions with empirical evaluation to improve predictive validity and mortality prediction. The new definition identifies stages of mild, moderate, and severe ARDS associated with increased mortality rates.
Researchers found that clots are extremely rare in otherwise healthy children who suffer traumatic fractures. The study suggests that preemptive anti-coagulant medications should be reserved for children with underlying conditions that increase clotting risk.
Researchers have discovered a way to identify genetic variants linked to postnatal depression, paving the way for a simple blood test. Women with specific genetic markers are more likely to develop postnatal depression, which can have significant effects on their mental health and children's development.
Researchers found tPA is safe for warfarin-treated stroke patients, with similar bleeding risks regardless of medication use. The study suggests tPA should not be withheld from these patients, as it minimizes brain damage and disability.
A new study published in JAMA found that the CKD-EPI equation for calculating GFR is a more accurate predictor of kidney disease risk compared to the MDRD Study equation. The study suggests that switching to the CKD-EPI equation could lead to better assessment of patient future risk and improved treatment of kidney disease.
A new study from the University of Toronto found that blood drive donations increased by 15 to 20 percent when incentives such as gift cards were offered. The study analyzed data from over 14,000 blood drives and a field experiment, suggesting that rewards can attract more donors.
Scientists at the University of Liverpool developed a new X-ray technique to identify tissue fibers in the heart that ensure regular heartbeat. The 3D images could help medics develop ways to reduce the risk of fibrillation, a condition where heart muscle contracts chaotically.
A recent study by Loyola Medicine found that even relatively minor burns can lead to serious complications and prolonged hospital stays for binge drinkers. The study compared burn patients who were intoxicated above the legal limit with those who had no alcohol in their blood, finding similar rates of sepsis and pneumonia.
Researchers found that stopping anti-clotting medication in patients with irregular heartbeats increases the risk of stroke within a month. The study analyzed data from over 14,000 patients and found that both warfarin and rivaroxaban carried similar stroke risks after temporary or permanent discontinuation.
A new study reveals that outpatient surgery patients are at risk for blood clots due to multiple factors such as age, surgery length, and type of procedure. The study suggests a need for better screening and prevention strategies in the growing outpatient surgery population.
A new method developed by the University of Copenhagen allows researchers to track mammal species in Southeast Asian rainforests using DNA-analysis from collected leeches. The technique has been successfully tested on local Vietnamese mammals, including rare species, and could revolutionize the monitoring of threatened wildlife.
Researchers have identified a microRNA, miR-625-3p, that can accurately diagnose malignant pleural mesothelioma with an accuracy of 82.4%. Additionally, high-dose radiotherapy has shown promising response rates for patients with disease confined to one side of the chest.
A new blood test can diagnose major depression in teens with high accuracy, distinguishing between subtypes such as major depression with anxiety disorder. The test's development holds promise for tailored treatments and reduced stigma around the disease.
A new study suggests that targeting the glucagon pathway could be an effective way to lower blood sugar levels without disrupting other functions of this hormone. Researchers found that blocking calcium signaling through CaMKII can regulate hepatic glucose production, leading to improved insulin sensitivity and reduced liver fat.
A study published in Diabetes Care found that high levels of phthalate metabolites are associated with an increased risk of developing diabetes. The research, conducted among over 1,000 elderly individuals, suggests a connection between environmental chemicals and the development of type-2 diabetes.
A new study reveals that overweight pregnant women with mildly elevated blood sugar levels are at a higher risk of adverse pregnancy outcomes than previously thought. These women, who do not have gestational diabetes or obesity, carry significant risks for their health and the health of their babies.
A new blood test has been developed to detect breast cancer recurrence up to 11-12 months before current tests, using a combination of biomarkers and mass spectrometry. The test shows promise for improving therapy outcomes by enabling earlier detection and treatment.
Researchers from Mount Sinai School of Medicine presented several studies at the American College of Cardiology's annual scientific session. One study found that aggressive statin therapy reduced fat content in coronary blockage by 22 percent, while another showed that cardiovascular disease screening can identify risk factors and symp...
A study published in the American Chemical Society found that capsaicinoids, a compound in chili peppers, can lower cholesterol levels and increase blood flow to the heart. The compounds may also reduce the formation of atherosclerotic plaques in blood vessels.
A new study led by UC Riverside's Alexander Raikhel aims to control mosquito population through hormonal regulation. The researchers will focus on deciphering genes involved in mediating hormone action during egg production in Aedes aegypti mosquitoes, which spread dengue and yellow fever.
Researchers found that thromboembolic events following ankle fracture surgery are uncommon, with most patients experiencing no complications. The study suggests that surgical treatment for ankle fractures does not significantly increase the risk of blood clots or pulmonary embolism.
Blood testing for food sensitivity is increasingly common, but its limitations and potential misuse have been emphasized by European and American allergy and immunology societies. Physicians should caution patients about the controversy surrounding IgG4 testing and advise them on alternative diagnostic approaches.
Researchers have discovered that a retrotransposon element is responsible for inducing anthocyanin production in blood oranges when exposed to cold conditions. This finding has significant implications for the future of blood orange production, potentially allowing for reliable worldwide cultivation and increasing their availability as...
Researchers found that 38% of kissing bugs in Arizona and California contained human blood, carrying the parasite that causes Chagas disease. The study raises awareness about the potential for transmission in the US, where the disease is currently rare.
A study using integrative Personal Omics Profiling (iPOP) combines genome sequencing, disease risk analysis, and molecular measures to capture changes in human biology. The researchers observe tens of thousands of components over two years, revealing dynamic molecular-level changes that provide meaningful physiological information.
Scientists have discovered how to control the Ruby gene, which is associated with improved cardiovascular health and reduced obesity. This breakthrough could lead to genetically engineered blood oranges that can thrive in warmer climates without cold dependency.
Researchers have solved the atomic structure of closed plasminogen, a key player in the clot-busting process, revealing an 'Achilles' heel' that proteins bind to when it opens up. This discovery may lead to more effective clot-busting drugs for treating heart attacks and strokes.
Researchers at Monash University have discovered how a blood clot-busting enzyme is switched on, revealing a 'peek-a-boo' mechanism that could lead to new treatments for clotting and bleeding disorders. The findings also provide insights into the molecular details of current plasminogen-activating drugs.
Researchers at Tel Aviv University have created protein-based transistors using organic materials found in the human body, offering a biodegradable alternative to traditional silicon-based technology. The transistors are self-assembling and can be tailored for unique properties such as conductivity, memory storage, and fluorescence.
A prenatal remediation strategy targeting homes of pregnant women significantly reduced childhood lead poisoning and lower blood lead levels in children. The study found that 62.5% of homes underwent remediation, compared to 28.2% in Philadelphia, where a similar program did not show the same results.
Researchers found an enzyme called IDO helps clear cellular debris and promote tolerance to the body's own proteins and DNA. Blocking IDO can trigger autoimmune diseases like lupus in genetically programmed mice.
A new study has found that foreign-born immigrant women from the Caribbean are at a higher risk of elevated mercury levels in their blood. Mercury exposure is particularly concerning for infants and children due to potential damage to cognitive and central nervous system development. The study suggests that community education efforts ...
A study found that injectable Low Molecular Weight Heparin (LMWH) treatment increased clot prevention rates compared to warfarin-based therapy in advanced cancer patients. Despite being recommended by guidelines, LMWH use is low due to patient preference for oral warfarin.
Researchers at Arizona State University have identified over 1,200 proteins in umbilical cord blood, providing valuable information for the identification of biomarkers. The findings represent a significant advance in the discovery of early warning indices of disease and toxic exposure.
High levels of cadmium in females and lead in males are associated with delayed pregnancy, according to a NIH study. Couples can reduce exposure by avoiding cigarettes or taking steps to minimize lead-based paint exposure.
Henry Ford Hospital researchers have identified two molecules that hold promise as a biomarker for measuring cartilage damage associated with osteoarthritis. Non-coding RNAs in blood were found to be associated with mild cartilage damage in patients one year after ACL reconstruction surgery.
In a large head-to-head study, warfarin and aspirin showed similar efficacy in reducing mortality and stroke risk in patients with heart failure and normal heart rhythms. Warfarin was found to be more effective in preventing strokes after four years of treatment.
Researchers used whole-exome sequencing to diagnose a type of severe metabolic disease, identifying the genetic mutation responsible. The study showcases the potential for this technique to aid in diagnosing congenital disorders of glycosylation, offering new hope for families affected by these conditions.
The Solitaire With the Intention for Thrombectomy (SWIFT) trial showed that the new device opened blocked vessels without causing symptomatic intracranial hemorrhage in 61% of patients, compared to 24% with the MERCI retriever. The device also led to better survival three months after stroke, with a 17.2% mortality rate versus 38.2% wi...
Researchers developed a minimally invasive treatment to dissolve brain blood clots, increasing patients' independence by 10-15% six months post-procedure. The technique reduces the need for craniotomy surgery and is as safe as supportive therapy.
The SOLITAIRE Flow Restoration Device outperformed the standard mechanical treatment in removing blood clots from blocked brain arteries in stroke patients. The new device resulted in a 61% success rate compared to 24% for the older device, leading to better survival rates and reduced mortality.
Research suggests that erratic heart rhythms, particularly paroxysmal atrial fibrillation (PAF), contribute to about one-fifth of unexplained strokes. Patients with stroke of unknown origin may benefit from extended monitoring and treatment with medications like dabigatran and rivaroxaban.
Researchers have developed a small device that measures blood oxygen levels and can be used to monitor hospitalized patients for recurrent strokes in real time. The device has shown statistically similar results to traditional CT perfusion scans, but may not be suitable for all patients.
The development of a new standard for vitamin D testing aims to ensure accurate measurements of vitamin D levels in the blood. The researchers created a certified reference material, SRM 972, which provides a mechanism to ensure measurement accuracy and comparability.
Male infants exposed to high levels of prenatal testosterone are twice as likely to experience language delays compared to females. The study found that higher levels of prenatal testosterone increased the likelihood of language development delays in males.
Researchers found that smokers with elevated blood lead levels are at a higher risk of developing renal cell carcinoma. The study analyzed data from the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study and found an association between blood lead levels and kidney cancer risk.
Researchers at Brown University have developed a biochip that can measure glucose levels in saliva, providing a potential solution for non-invasive diabetes monitoring. The biochip uses surface plasmonics to detect glucose molecules in water, with results showing concentrations similar to those found in human saliva.
A study by Max Planck researchers found that looking at pictures of food increases the hormone ghrelin in the blood, leading to feelings of hunger. This suggests that external stimuli like advertising can contribute to weight gain in Western populations.
High levels of TNF receptors in the blood increase diabetes patients' risk of developing kidney problems by three- to five-fold. Measuring blood levels of TNF receptors may help predict which patients' kidneys are in jeopardy, and targeting TNF receptors may help protect them.
A recent study by Michael McClean and colleagues reveals a strong link between PFC levels in office air and blood concentrations, suggesting offices as an important exposure environment. The findings also indicate that workers in newly renovated buildings receive higher doses of PFCs.
Researchers at Boston University School of Medicine debunked the concept that excess salt causes high blood pressure by stimulating the sympathetic nervous system to produce adrenalin, causing artery constriction. The study suggests that diuretics may not be enough to treat hypertension cases associated with renal failure and recommend...
A study found that patients with blood potassium levels between 3.5 and less than 4.5 mEq/L had a lower risk of death than those with levels higher or lower than this range after a heart attack. The optimal range of serum potassium levels in AMI patients may be between 3.5 and 4.5 mEq/L.
A report by European Menopause and Andropause society recommends vitamin D supplements for postmenopausal women to maintain blood levels above 30 ng/ml, improving bone health and reducing fracture risk. Experts also suggest a daily intake of 600-4,000 IU/day, depending on age and risk factors.
A new research study published in The FASEB Journal suggests a simple blood test can predict fetal gender as early as the first trimester. The test measures the ratio of enzymes DYS14 and GAPDH in maternal plasma, indicating if the baby will be a boy or girl.
Young diabetics struggle with blood sugar control, school performance, and misbehavior due to lighter sleep and breathing problems. Sleep apnea also contributes to compromised health outcomes.
A study found that people with diets high in omega-3 fatty acids and certain vitamins had lower brain shrinkage and better mental thinking test scores compared to those with low nutrient intake. The study also showed that trans fats, commonly found in processed foods, were linked to increased brain shrinkage.
Research found that elderly individuals with high levels of vitamins B, C, D, E, and healthy oils from fish performed better on mental acuity tests and had less brain shrinkage. Conversely, those consuming 'junk food' diets showed decreased cognitive performance.
Allergy tests are not magic bullets for diagnosis, according to new guidelines from Johns Hopkins Medicine. Blood and skin tests should be used to confirm suspicion and monitor established allergies, but not as standalone diagnostic strategies. This approach aims to prevent misdiagnosis and unnecessary restrictions on patients.
Researchers developed a new navigation system that can accurately steer microbots through complex blood vessels, enabling precise drug delivery or tumor destruction. The system uses an external magnetic field to generate two distinct types of microbot movements: helical and translational motions.
Researchers analyzed data from a large study to find that certain protein markers in the blood, such as cystatin C and beta trace protein, are better predictors of an individual's prognosis than creatinine. These markers may indicate not only kidney health but also other aspects of well-being.