Articles tagged with Blood
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A recent study published in JAMA found that the rate of community-onset MRSA infections has decreased significantly among US military personnel. Community-onset skin and soft tissue infections due to MRSA peaked at 62% in 2006 before declining annually, with a proportion of 52% in 2010.
Researchers at the University of Cincinnati discovered a new gene target for leukemia therapy by inhibiting the protein Vav3, which controls cell signaling. This finding could lead to cellular targets for patients with BCR-ABL lymphoid leukemia, a type of leukemia with poor treatment outcomes.
Patients who refuse transfusion following cardiac surgery, particularly Jehovah's Witnesses, experience lower morbidity and mortality rates compared to those who receive blood transfusions. They also show fewer complications such as heart attacks and longer hospital stays, while having better long-term survival rates.
A new study presented at The Endocrine Society's 94th Annual Meeting has found that monitored vitamin D therapy is safe for patients with primary hyperparathyroidism and vitamin D deficiency. Vitamin D treatment helped lower parathyroid hormone levels, but did not raise calcium blood levels in patients.
A new study suggests long-term calcium and vitamin D supplement use is linked to high urinary levels of calcium, potentially increasing the risk of kidney stones. The researchers found that approximately 33% of participants developed hypercalciuria, which was unrelated to vitamin D dosage.
A comprehensive study confirms lead-based ammunition as the primary source of lead in California condors, preventing their recovery. The condor population can only be sustained through intensive and costly management efforts without a solution to the problem of lead poisoning.
Two new blood tests for vitamin D are prone to errors, leading to misdiagnoses and potential overtreatment. Inaccuracies were found in 40-48% of test results, with significant discrepancies between methods.
A new study finds that physical fitness significantly lowers the risk of death in diabetes patients with heart abnormality. Diabetic patients who were physically fit had a lower risk of death compared to those who were not physically fit, regardless of the presence or absence of left ventricle wall thickness.
A team of scientists from Washington University in St. Louis has identified the eastern gray squirrel as a major animal reservoir for tick-borne diseases, including ehrlichioses and STARI. The study uses a new assay to detect species-level tick blood meals, confirming the presence of gray squirrel DNA in infected ticks.
A Baylor University study reveals that juvenile rats build up a physical tolerance to alcohol but not cognitive impairment. This finding has significant implications for understanding adolescent behavior and the development of alcoholism.
A French cohort study of 6,000 women aged over 65 found that high levels of estrogen are associated with an increased risk of myocardial infarction and strokes. The study challenges the long-held assumption that estrogen has a protective effect on the heart and blood vessels.
Researchers have developed a simple blood test that can identify patients who will not respond to the painkiller tramadol. The test measures the ratio of tramadol's metabolite O-demethyltramadol (ODT) to tramadol itself, allowing doctors to switch non-responding patients to alternative painkillers like morphine.
Researchers discovered that vampire jumping spiders prefer female mosquitoes with blood-fed abdomens over other insects due to their distinctive antennae. The spiders can identify the females by their antennae even when they are too small to be seen, and this unique ability may play a crucial role in their prey classification process.
A simple blood test can identify people at high risk of dying within a month after non-cardiac surgery. The test called Troponin T measures protein markers of heart injury and is strongly associated with 30-day mortality.
A new blood test discovered circulating tumour cells can predict progression-free survival and overall survival in early-stage breast cancer patients. The presence of CTCs is associated with worse survival rates, but the correlation increases when concentrations are higher.
A study of over 247,000 Copenhageners found higher mortality rates for both too little and too much vitamin D in the blood. The results challenge long-held assumptions about the essential nutrient's benefits.
A new NIH-funded study examines the use of mobile technology to improve diet and physical activity behavior in adults. The study found that a combination of mobile technology and remote coaching holds promise in encouraging healthier eating habits and reducing sedentary leisure time.
The updated Berlin Definition of ARDS combines consensus discussions with empirical evaluation to improve predictive validity and mortality prediction. The new definition identifies stages of mild, moderate, and severe ARDS associated with increased mortality rates.
Researchers found that clots are extremely rare in otherwise healthy children who suffer traumatic fractures. The study suggests that preemptive anti-coagulant medications should be reserved for children with underlying conditions that increase clotting risk.
Researchers have discovered a way to identify genetic variants linked to postnatal depression, paving the way for a simple blood test. Women with specific genetic markers are more likely to develop postnatal depression, which can have significant effects on their mental health and children's development.
Researchers found tPA is safe for warfarin-treated stroke patients, with similar bleeding risks regardless of medication use. The study suggests tPA should not be withheld from these patients, as it minimizes brain damage and disability.
A new study published in JAMA found that the CKD-EPI equation for calculating GFR is a more accurate predictor of kidney disease risk compared to the MDRD Study equation. The study suggests that switching to the CKD-EPI equation could lead to better assessment of patient future risk and improved treatment of kidney disease.
A new study from the University of Toronto found that blood drive donations increased by 15 to 20 percent when incentives such as gift cards were offered. The study analyzed data from over 14,000 blood drives and a field experiment, suggesting that rewards can attract more donors.
Scientists at the University of Liverpool developed a new X-ray technique to identify tissue fibers in the heart that ensure regular heartbeat. The 3D images could help medics develop ways to reduce the risk of fibrillation, a condition where heart muscle contracts chaotically.
A recent study by Loyola Medicine found that even relatively minor burns can lead to serious complications and prolonged hospital stays for binge drinkers. The study compared burn patients who were intoxicated above the legal limit with those who had no alcohol in their blood, finding similar rates of sepsis and pneumonia.
Researchers found that stopping anti-clotting medication in patients with irregular heartbeats increases the risk of stroke within a month. The study analyzed data from over 14,000 patients and found that both warfarin and rivaroxaban carried similar stroke risks after temporary or permanent discontinuation.
A new study reveals that outpatient surgery patients are at risk for blood clots due to multiple factors such as age, surgery length, and type of procedure. The study suggests a need for better screening and prevention strategies in the growing outpatient surgery population.
A new method developed by the University of Copenhagen allows researchers to track mammal species in Southeast Asian rainforests using DNA-analysis from collected leeches. The technique has been successfully tested on local Vietnamese mammals, including rare species, and could revolutionize the monitoring of threatened wildlife.
Researchers have identified a microRNA, miR-625-3p, that can accurately diagnose malignant pleural mesothelioma with an accuracy of 82.4%. Additionally, high-dose radiotherapy has shown promising response rates for patients with disease confined to one side of the chest.
A new blood test can diagnose major depression in teens with high accuracy, distinguishing between subtypes such as major depression with anxiety disorder. The test's development holds promise for tailored treatments and reduced stigma around the disease.
A new study suggests that targeting the glucagon pathway could be an effective way to lower blood sugar levels without disrupting other functions of this hormone. Researchers found that blocking calcium signaling through CaMKII can regulate hepatic glucose production, leading to improved insulin sensitivity and reduced liver fat.
A study published in Diabetes Care found that high levels of phthalate metabolites are associated with an increased risk of developing diabetes. The research, conducted among over 1,000 elderly individuals, suggests a connection between environmental chemicals and the development of type-2 diabetes.
A new study reveals that overweight pregnant women with mildly elevated blood sugar levels are at a higher risk of adverse pregnancy outcomes than previously thought. These women, who do not have gestational diabetes or obesity, carry significant risks for their health and the health of their babies.
A new blood test has been developed to detect breast cancer recurrence up to 11-12 months before current tests, using a combination of biomarkers and mass spectrometry. The test shows promise for improving therapy outcomes by enabling earlier detection and treatment.
Researchers from Mount Sinai School of Medicine presented several studies at the American College of Cardiology's annual scientific session. One study found that aggressive statin therapy reduced fat content in coronary blockage by 22 percent, while another showed that cardiovascular disease screening can identify risk factors and symp...
A study published in the American Chemical Society found that capsaicinoids, a compound in chili peppers, can lower cholesterol levels and increase blood flow to the heart. The compounds may also reduce the formation of atherosclerotic plaques in blood vessels.
A new study led by UC Riverside's Alexander Raikhel aims to control mosquito population through hormonal regulation. The researchers will focus on deciphering genes involved in mediating hormone action during egg production in Aedes aegypti mosquitoes, which spread dengue and yellow fever.
Researchers found that thromboembolic events following ankle fracture surgery are uncommon, with most patients experiencing no complications. The study suggests that surgical treatment for ankle fractures does not significantly increase the risk of blood clots or pulmonary embolism.
Blood testing for food sensitivity is increasingly common, but its limitations and potential misuse have been emphasized by European and American allergy and immunology societies. Physicians should caution patients about the controversy surrounding IgG4 testing and advise them on alternative diagnostic approaches.
Researchers have discovered that a retrotransposon element is responsible for inducing anthocyanin production in blood oranges when exposed to cold conditions. This finding has significant implications for the future of blood orange production, potentially allowing for reliable worldwide cultivation and increasing their availability as...
Researchers found that 38% of kissing bugs in Arizona and California contained human blood, carrying the parasite that causes Chagas disease. The study raises awareness about the potential for transmission in the US, where the disease is currently rare.
A study using integrative Personal Omics Profiling (iPOP) combines genome sequencing, disease risk analysis, and molecular measures to capture changes in human biology. The researchers observe tens of thousands of components over two years, revealing dynamic molecular-level changes that provide meaningful physiological information.
Scientists have discovered how to control the Ruby gene, which is associated with improved cardiovascular health and reduced obesity. This breakthrough could lead to genetically engineered blood oranges that can thrive in warmer climates without cold dependency.
Researchers have solved the atomic structure of closed plasminogen, a key player in the clot-busting process, revealing an 'Achilles' heel' that proteins bind to when it opens up. This discovery may lead to more effective clot-busting drugs for treating heart attacks and strokes.
Researchers at Monash University have discovered how a blood clot-busting enzyme is switched on, revealing a 'peek-a-boo' mechanism that could lead to new treatments for clotting and bleeding disorders. The findings also provide insights into the molecular details of current plasminogen-activating drugs.
Researchers at Tel Aviv University have created protein-based transistors using organic materials found in the human body, offering a biodegradable alternative to traditional silicon-based technology. The transistors are self-assembling and can be tailored for unique properties such as conductivity, memory storage, and fluorescence.
A prenatal remediation strategy targeting homes of pregnant women significantly reduced childhood lead poisoning and lower blood lead levels in children. The study found that 62.5% of homes underwent remediation, compared to 28.2% in Philadelphia, where a similar program did not show the same results.
Researchers found an enzyme called IDO helps clear cellular debris and promote tolerance to the body's own proteins and DNA. Blocking IDO can trigger autoimmune diseases like lupus in genetically programmed mice.
A new study has found that foreign-born immigrant women from the Caribbean are at a higher risk of elevated mercury levels in their blood. Mercury exposure is particularly concerning for infants and children due to potential damage to cognitive and central nervous system development. The study suggests that community education efforts ...
A study found that injectable Low Molecular Weight Heparin (LMWH) treatment increased clot prevention rates compared to warfarin-based therapy in advanced cancer patients. Despite being recommended by guidelines, LMWH use is low due to patient preference for oral warfarin.
Researchers at Arizona State University have identified over 1,200 proteins in umbilical cord blood, providing valuable information for the identification of biomarkers. The findings represent a significant advance in the discovery of early warning indices of disease and toxic exposure.
High levels of cadmium in females and lead in males are associated with delayed pregnancy, according to a NIH study. Couples can reduce exposure by avoiding cigarettes or taking steps to minimize lead-based paint exposure.
Henry Ford Hospital researchers have identified two molecules that hold promise as a biomarker for measuring cartilage damage associated with osteoarthritis. Non-coding RNAs in blood were found to be associated with mild cartilage damage in patients one year after ACL reconstruction surgery.
In a large head-to-head study, warfarin and aspirin showed similar efficacy in reducing mortality and stroke risk in patients with heart failure and normal heart rhythms. Warfarin was found to be more effective in preventing strokes after four years of treatment.
Researchers used whole-exome sequencing to diagnose a type of severe metabolic disease, identifying the genetic mutation responsible. The study showcases the potential for this technique to aid in diagnosing congenital disorders of glycosylation, offering new hope for families affected by these conditions.
The Solitaire With the Intention for Thrombectomy (SWIFT) trial showed that the new device opened blocked vessels without causing symptomatic intracranial hemorrhage in 61% of patients, compared to 24% with the MERCI retriever. The device also led to better survival three months after stroke, with a 17.2% mortality rate versus 38.2% wi...
Researchers developed a minimally invasive treatment to dissolve brain blood clots, increasing patients' independence by 10-15% six months post-procedure. The technique reduces the need for craniotomy surgery and is as safe as supportive therapy.
The SOLITAIRE Flow Restoration Device outperformed the standard mechanical treatment in removing blood clots from blocked brain arteries in stroke patients. The new device resulted in a 61% success rate compared to 24% for the older device, leading to better survival rates and reduced mortality.
Research suggests that erratic heart rhythms, particularly paroxysmal atrial fibrillation (PAF), contribute to about one-fifth of unexplained strokes. Patients with stroke of unknown origin may benefit from extended monitoring and treatment with medications like dabigatran and rivaroxaban.
Researchers have developed a small device that measures blood oxygen levels and can be used to monitor hospitalized patients for recurrent strokes in real time. The device has shown statistically similar results to traditional CT perfusion scans, but may not be suitable for all patients.