Articles tagged with Blood
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A University of Michigan Health System study found that peripherally inserted central catheters more than double the risk of blood clots in critically ill patients and those with cancer. The device is often used for IV medication delivery and has lower infection risks, but may not be suitable for all patients.
A recent study published in the Journal of Rehabilitation Research and Development found that patients who have suffered a stroke respond equally to care efforts, regardless of their age. The research looked at 3,196 patients treated for ischemic strokes and found little difference in health quality across different age groups.
Researchers have developed a blood test that can detect allergies to nickel, cobalt, and bone cement, allowing patients to avoid miserable reactions and expensive revisions. The new test is expected to be widely used in the next couple of years, improving patient outcomes and reducing healthcare costs.
Researchers at the Montreal Heart Institute have discovered a blood protein that contributes to the early development of atherosclerosis. Angiopoietin-like protein 2 (angptl2) is found six times higher in subjects with coronary heart disease than healthy individuals, making it a potential early biomarker for the condition.
Harvard Stem Cell Institute researchers have identified a protein, GDF-11, that reverses the effects of aging on mouse hearts. The protein was found to reduce heart size and thickness, similar to healthy younger mice.
Researchers at the University of Iowa found similar PCB concentrations in mothers and children from East Chicago and Columbus Junction, challenging long-held assumptions about urban-rural differences in chemical exposure. The study detected a greater variety of PCBs in the blood of mothers and children in East Chicago, but ultimately s...
A study found that children living near toxic waste sites in lower and middle income countries have high blood lead levels, resulting in a loss of IQ points and higher incidence of mental retardation. The researchers estimated that 6 out of every 1,000 children could experience mild mental retardation.
A team of researchers has developed an innovative injectable nano-network that can effectively control blood sugar levels in diabetics by releasing insulin when needed, maintaining normal levels for over a week. The technology has the potential to improve the health and quality of life of diabetes patients.
A recent study at Lund University has discovered a key factor behind gastric bypass surgery's ability to rapidly send type 2 diabetes into remission. The researchers found that insulin levels and intestinal hormones increase significantly after the procedure, suggesting a new potential treatment avenue for diabetes patients.
New research from Johns Hopkins finds that high doses of vitamin D supplements do not confer additional benefits on cardiovascular health or longevity in healthy adults. However, elderly individuals, postmenopausal women, and those with kidney disease may still benefit from higher blood levels of the sunshine vitamin.
A study of 422,000 people found that the safe range of vitamin D levels lies between 20 to 36 ng/mL. Vitamin D deficiency was linked to increased risk of acute coronary morbidity or mortality, while elevated levels above 36 ng/mL were associated with a slightly higher risk.
A clinical study in over 4,000 subjects found a correlation between high blood levels of trimethylamine N-oxide (TMAO) and increased future risks of death, nonfatal heart attack, or stroke. TMAO is produced when intestinal bacteria digest phosphatidylcholine, commonly found in animal products.
Researchers demonstrate rapid and sensitive identification of specific Candida species directly from whole blood using T2Candida, reducing mortality rate to 11%. The breakthrough approach enables fast detection in approximately three hours, outperforming current gold standard methods.
A specific form of vitamin E supplement can accelerate heart health benefits after quitting smoking. Smokers who took the gamma-tocopherol form showed a 19% greater drop in cardiovascular disease risk and improved vascular function.
Research suggests that fainting, also known as vasovagal syncope, may have a genetic component, with some families affected by multiple genes. Triggers such as emotional distress, pain, and frightening thoughts vary greatly within families, but the study found no link between triggers and genetic inheritance.
A new study shows stent grafts can successfully keep dialysis access sites open using tiny scaffolds for far longer than previously reported, reducing the need for invasive treatments and improving patients' quality of life.
New study finds MR images taken during systole phase show more accurate detection of myocardial scars in ischemic cardiomyopathy patients. Systolic images revealed scars not visible on diastolic images, particularly in the left ventricle area prone to ischemic damage.
A recent study published in Cell Reports reveals that obesity is linked to autoimmune disease, but researchers have found a potential solution. Blocking the AIM molecule may prevent autoantibody production and related autoimmune responses.
Researchers at ETH Zurich have developed a new method to analyze the chemical composition of exhaled breath, revealing an individual's unique 'breathprint' that stays constant over time. This non-invasive approach holds promise for early disease detection and monitoring, and could potentially replace traditional blood and urine analysis.
A large population-based study found that stillbirth and pre-term birth are associated with a significantly increased risk of blood clots after pregnancy. The study identified several factors that increase the risk of blood clots, including obesity, caesarian section delivery, and pre-term birth.
A study published in the journal Blood found that pregnant and postnatal women with certain medical conditions, such as varicose veins or heart disease, are at higher risk of developing blood clots. The research also identified other risk factors, including obesity, bleeding during pregnancy or labour, and a history of premature birth.
A UC Davis study found large variation in the use of metal inferior vena cava filters among California hospitals, despite little evidence of their safety and effectiveness. The researchers recommend additional research to determine if the devices improve outcomes for patients with venous thromboembolism.
Researchers at UC Davis developed a nomogram to calculate individual patient risk of post-surgical venous thromboembolism, allowing clinicians to tailor prevention efforts. The study analyzed over 470,000 surgical patients and identified factors increasing blood clot risk, including age, BMI, and splenectomies.
A new study published in Hepatology found that hepatitis C transmission from an infected partner during sex is extremely rare in monogamous heterosexual relationships. The researchers recruited 500 couples and found a maximum incidence rate of 0.07% per year, equivalent to roughly 1 case per 190,000 sexual contacts.
Researchers at the University of Pittsburgh are developing a wearable artificial lung to serve as a bridge to transplant or recovery in patients with acute and chronic lung failure. The device, called PAAL, is designed to provide longer-term respiratory support while maintaining excellent blood compatibility.
EPFL scientists have developed a tiny implant that can analyze proteins and organic acids in the blood, sending results to doctors' computers for more personalized care. The device has demonstrated reliable detection of several substances and has potential applications in chemotherapy and chronic illness monitoring.
A study conducted at Boston Medical Center found that IVC filters are often left in place indefinitely due to low retrieval rates and inconsistent anticoagulant use. A new multi-disciplinary team approach has been implemented to track and retrieve filters, resulting in successful removals of 10 out of 36 eligible filters.
Researchers led by Dr. Michael A. Weiss are developing a rapid-acting, glucose-responsive insulin that can reduce the risk of hypoglycemia in diabetes patients. The new form of insulin will be designed to detect high or low glucose levels and release only as needed.
The study found that a single dose of tenecteplase reduced incidence of circulatory system collapse by 56% in patients with submassive or intermediate-risk pulmonary embolism. Patients under 75 years old had the most benefit and fewer hemorrhagic strokes.
Researchers found that frequent head hits in football players can lead to long-term brain changes, even without concussions. Elevated levels of S100B protein in blood tests correlated with brain tissue damage and autoimmune responses.
A new study identifies a link between carbamylated albumin protein and increased risk of heart disease in kidney dialysis patients. Researchers found that measuring carbamylated albumin may help doctors monitor dialysis patients and identify those at risk of cardiac complications.
A new method for estimating blood loss, based on base deficit (BD), is more accurate than the current Advanced Trauma Life Support (ATLS) classification. BD was linked to increased severity of injury, length of stay, morbidity and mortality.
A Wayne State University study found seasonal fluctuations in blood lead levels among children are linked to resuspended dust contaminated with lead. The research, based on nine years of data from over 367,000 children, highlights the need for improved controls to prevent lead exposure.
A study of over 40,000 Kaiser Permanente patients found no increased risk of infection or complications following total knee replacement (TKR) for those with diabetes. However, patients with uncontrolled diabetes were more likely to be obese and have severe comorbidities.
A new study found that exposure to airborne dust in urban areas leads to an increase and decrease in childhood blood lead levels, respectively. The research suggests that focusing on primary prevention of lead-contaminated soils may be a more effective approach to improving child health than current efforts.
Studies show dialysis patients using catheters face higher risks of death, infections, and cardiovascular events compared to those with arteriovenous fistulas or grafts. Higher quality studies are needed to determine the true safety of different types of vascular access.
Efforts to reduce lead pollution have been largely successful, but the problem persists due to new industrial inputs and consumer product contamination. Blood lead levels remain high, with no known threshold for toxicity, posing ongoing health risks to people and animals worldwide.
A recent analysis of almost 150 BPA studies shows that human exposure levels are likely too low for estrogenic effects. The study found that blood concentrations of BPA are many times lower than those causing toxicity in animals, suggesting that animal studies may not accurately reflect the human BPA experience.
Researchers at the University of York have developed a new dye, 'Mallard Blue', which can rapidly detect heparin levels in human serum. The dye has excellent sensing capacity for heparin and may improve upon existing clinical methods.
Research suggests that longer periods of low-intensity exercise improve insulin sensitivity and blood lipid levels more effectively than shorter bursts of intense activity. Standing and walking for extended durations are particularly beneficial.
Prompt identification and treatment of perioperative strokes can significantly improve neurologic outcomes. The article reviews management options for perioperative stroke, including blood thinners, clot-busting drugs, mechanical devices, ultrasound, and hemicraniectomy.
A new randomized controlled trial compared the effectiveness of mechanical clot removal with standard medical therapy in treating severe strokes. The study, led by Georgetown University Medical Center, found that removing blood clots within eight hours of stroke symptoms improved survival outcomes and reduced disability levels.
Researchers found that removing blood clots in the brain from patients experiencing severe strokes delivered no better outcomes than non-invasive standard medications. Imaging techniques were also not helpful in identifying patients who potentially would benefit most from clot removal.
Researchers found that minimally invasive delivery of tPA directly into brain clots improved functional recovery in patients with intracerebral hemorrhage, reducing hospital stays and costs. Patients who received the active tPA treatment recovered more quickly and independently after a year.
A study found that frequent dialysis can cause complications related to repeated access to the blood, including repair procedures and hospitalizations. The risk of these events was 76% higher with daily hemodialysis compared to conventional hemodialysis.
A genetic variant in the LPA gene has been identified as a major contributor to aortic valve calcification, increasing the risk by over 50%. Researchers found that people with this variant have higher levels of lipoprotein (a) cholesterol particles, which can lead to calcium deposits on the aortic valve.
A study published in Expert Review of Neurotherapeutics found that 10-15% of people experiencing transient ischemic attacks (TIAs) will suffer full strokes within three months. Rapid evaluation and treatment can reduce the risk of subsequent strokes by up to 80%.
A large study found that ABO blood type is a strong risk factor for venous blood clots. The research, published in the Canadian Medical Association Journal, also identified other genetic mutations associated with an increased risk of these conditions.
A new study from the University of Pennsylvania School of Medicine reveals high levels of approval among trauma patients, families, and communities to participate in clinical trials without express consent. The findings provide important clues for increasing studies aimed at improving care for time-sensitive injuries.
A New York-based physician-researcher has uncovered a potential connection between autism and insulin-like growth factor (IGF) levels in newborns, proposing a study to investigate this hypothesis. IGF plays a crucial role in brain development, and depressed levels may serve as a biomarker for the later development of autism.
A new genetic variant has been identified as a potential target for treatment in reducing stroke risk, with no association found in small vessel disease. The study highlights the need for individualized treatment approaches, given the different genetic mechanisms underlying various types of stroke.
Researchers at Johns Hopkins Medicine discovered four major adaptations in owl anatomy that enable them to rotate their heads almost fully without damaging delicate blood vessels. The team found contractile blood reservoirs and vascular network variations that allow owls to pool blood to meet energy needs during head rotation.
A new study from Ohio State University found a strong link between latent herpes virus reactivation and heart disease, particularly in patients who have suffered a heart attack. The researchers detected elevated levels of inflammatory proteins and antibodies to the EBV-encoded viral protein dUTPase in these patients.
A multicenter study reveals critically ill children with influenza exhibit lower TNFα production capacity compared to healthy control subjects. This degree of reduction in capacity was highly predictive of death from the illness.
A new study of 73,000 Danes found that 'ugly' cholesterol, a type of remnant-like particle cholesterol, is the direct cause of arteriosclerosis and ischaemic heart disease. High levels of ugly cholesterol triple the risk of heart disease, emphasizing the need for preventive treatment and lifestyle changes.
Two studies found that migraine with aura is a strong contributor to cardiovascular events like heart attack and stroke. Women with this condition are more likely to experience blood clot complications, especially those on newer contraceptives.
Serial compression ultrasonography with Doppler imaging is a reliable method for ruling out deep vein thrombosis in pregnant women, detecting 94% of cases. This approach safely allows physicians to withhold anticoagulation therapy, reducing unnecessary risks during pregnancy.
Researchers have identified a new approach to treating lymphoma by combining a toll-like receptor agonist with radiation, resulting in durable anti-tumor immune responses. Additionally, scientists have developed model-based decision rules to predict the safety of therapy discontinuation for patients with chronic myeloid leukemia.
A new study suggests a safer and more informative noninvasive test for detecting chromosomal defects in the fetus, using fetal DNA in the mother's blood. The method offers a cost-effective alternative to traditional invasive procedures, reducing risks of infection and potential harm to the fetus.
A specific protein, Protein S, is crucial for maintaining a healthy retina through photoreceptor pruning. This process prevents retinal degeneration and blindness. The study also highlights the protein's role in other systems, such as the immune and reproductive systems, where its activation has been observed.