Articles tagged with Blood
Researchers found that blood clots are rare in children undergoing spine operations, and most patients can be safely monitored without anti-clotting medication. High-risk groups include children with congenital scoliosis or spinal curvatures part of a syndrome, as well as older children.
Researchers at Saint Louis University discovered that deleting disordered sections of a protein's structure reveals the molecular mechanism of blood clotting. By crystallizing prothrombin, they found that the deleted version is activated to thrombin faster and provides key information on the mechanism of prothrombin activation.
Researchers from UCL and the Mayo Clinic argue that labelling people with moderately high blood sugar as pre-diabetic has no health benefits. The term could create significant burdens on healthcare systems without conferring any long-term health benefits.
A recent study of over 500,000 Danish women found no increased risk of venous thromboembolism following quadrivalent HPV vaccination. The research, published in JAMA, used data from national registers to evaluate the potential link between the vaccine and blood clots.
A study by Brown University researchers found that Rhode Island's Lead Hazard Mitigation Law has significantly reduced blood lead levels in children living in compliant buildings. However, only 20% of properties covered by the law were in compliance, with average lead levels still above 5 micrograms per deciliter in noncompliant homes.
A recent study found that even low levels of lead in children's blood are associated with increased risk of behavioral and emotional problems. As blood lead levels increase, so do the problems, highlighting the importance of reducing lead exposure in children.
A study of Chinese preschoolers found associations between moderately elevated blood lead concentrations and teacher-reported behavioral problems. The study suggests that further examination is needed to clarify the biological effects of environmental lead exposure on children's behavior.
Researchers discovered four rare APOC3 gene mutations that lower blood triglyceride levels and reduce the risk of coronary artery disease by 40%. The study suggests a powerful strategy for developing new drugs against heart disease.
Researchers found that people with a specific gene variation have lower blood lipids and a reduced risk of arteriosclerosis. The study, based on two large population studies, suggests that inhibiting apolipoprotein C3 could be an effective target for new drugs to prevent cardiovascular disease.
Researchers developed biomarkers from whole blood gene expression profiles to predict disease status at 12 months in children with newly diagnosed JIA. The study found strong predictive properties for disease status after four months of therapy, and identified different mechanisms of response in RF positive patients.
Researchers found that persons with lower blood vitamin D levels were twice as likely to die prematurely as those with higher levels, regardless of bone disease risks. The study supports previous findings on low vitamin D being hazardous and provides reassurance on safe dosing up to 4,000 IU/day.
A new assay can detect toxic prions in blood samples from humans with variant Creutzfeldt-Jakob Disease (vCJD) and asymptomatic animals. The test, developed by French researchers, was tested on vCJD patients and non-infected controls, accurately identifying infected individuals.
A recent study found that frequent use of permanent dyes and perming treatments may expose hairdressers to banned aromatic amines, linked to increased cancer risk. The researchers recommend protective measures such as wearing gloves to minimize skin exposure.
Researchers at Mount Sinai Hospital discovered that a protein called Sirtuin1 (SIRT1) is essential for maintaining healthy aging of blood stem cells. The study found that loss of SIRT1 leads to impaired regeneration and resembles aged, defective stem cells in mouse models.
Researchers at Mayo Clinic have developed an optical blood oxygen sensor attached to an endoscope that can identify pancreatic cancer with a sensitivity of 92% and specificity of 86%. The device measures changes in blood flow near the pancreas, which tumors alter to grow. Early detection is crucial as most pancreatic cancers are diagno...
A study by University of Illinois Chicago found that patients with alcohol in their blood had a reduced risk of developing cardiac and renal complications, resulting in lower mortality rates. The protective effect was observed even after the alcohol was metabolized.
A large study finds that high levels of certain air pollutants are associated with a higher risk of cardiovascular problems, including irregular heart rhythms and lung blood clots. The research suggests that particulate matter is particularly harmful for elderly people.
A study found that preventive implantation of ICDs in patients with less severe heart failure (LVEF 30-35%) significantly reduces mortality rates at 3 years compared to those without an ICD. The analysis also showed improved survival in patients with LVEF < 30%.
A study from Duke University Medical Center found that implantable cardioverter defibrillators improve survival among heart failure patients with a left ventricular ejection fraction of 30-35%. The device reduces three-year mortality rates by 3.6% in patients without ICDs.
A standardized prevention program implemented in a hospital department of surgery significantly reduced the rate of deep venous thromboses (DVT) and pulmonary emboli among patients. The program, which scored individual risk factors and provided risk-based prophylaxis, led to an 84% drop in DVT rates and a 55% decrease in pulmonary emboli.
Researchers tracked real-time virus replication and drug clearance in HCV patients, revealing a lag between liver and blood viral decay. The findings suggest the need for tailored therapy to achieve viral eradication and may inform vaccine development.
A new Vanderbilt University study found that women with blood in their urine were less likely to be referred to a urologist for further tests than men with the same issue. The disparity may contribute to delayed diagnoses and worse mortality rates among women with bladder cancer.
Research at Washington University School of Medicine found that vitamin D supplements had a limited benefit for asthma treatment. Patients who achieved sufficient blood levels of vitamin D showed improved asthma control, including reduced treatment failures and asthma attacks.
A new study found that a single episode of binge drinking can cause bacterial leakage from the gut into the bloodstream, leading to increased levels of toxins. This results in an immune response, producing fever, inflammation, and tissue destruction, according to researchers at UMMS.
A blood test has been developed to predict impending preterm birth, distinguishing between true and false labor in 70% of cases. The new test outperforms existing methods by using a set of nine genes coupled with clinical data, allowing for all women to be screened as part of routine blood work.
A new study by Uppsala University reveals that high levels of PCBs in the blood significantly increase the risk of dying among smokers and former smokers. For non-smokers, no elevated risk was found after eight years.
Researchers discovered that elephant seals have high levels of carboxyhemoglobin, similar to those found in heavy human smokers. The team suggests that this may provide protective effects against oxidative damage, potentially benefiting the animals' health. Further study is needed to fully understand the significance of these findings.
A study by Intermountain Medical Center found that AFib patients on blood thinning medications are at higher risk of developing dementia if their doses are not within the optimal recommended range. Patients with dosages outside this range were 4.5 times more likely to develop dementia.
GDF11 protein improves the exercise capability of aging mice by making their brains and skeletal muscles more like those of young health mice. The protein also restores DNA damage associated with aging in muscle stem cells, leading to improved function in unmanipulated muscle.
A study published in ACS' Journal of Proteome Research found that whey protein slows down stomach emptying and lowers fatty acid levels, increasing insulin levels in obese adults. The results suggest that whey protein may be a beneficial addition to diets for those at risk of developing type-2 diabetes and cardiovascular disease.
A recent study published in Scientific Reports analyzed the DNA recovered from a relic attributed to Louis XVI and found it did not match his expected genetic profile. The analysis revealed a clear French and Italian component, contradicting historical accounts of Louis XVI's physical appearance.
A study published in Cell Transplantation found that injecting autologous peripheral blood stem cells into the brain of stroke patients improved their motor function. The treatment was safe and feasible in patients who suffered a prior stroke, with significant improvements in clinical outcomes measures.
A new prediction tool can help doctors identify patients at highest risk for respiratory failure after surgery, allowing them to take measures to prevent the condition. The tool uses nine predictors to determine a patient's risk level, enabling doctors to assign risk levels and use preventive measures more effectively.
A study analyzing nearly three decades of data found chromium supplements are ineffective in reducing fasting glucose levels in both diabetic and non-diabetic populations. Despite this, the researchers suggest other dietary supplement ingredients may have positive effects on fasting blood sugar levels.
Scientists have developed a device that can process whole blood and isolate genetic material for two potential biomarkers within minutes. This rapid detection method could help determine the course of proper treatment, potentially saving lives.
A study published by Johns Hopkins Medicine found that DNA modifications in the blood of stressed mice correlate with changes in brain tissue, providing a valid comparison between the two. The research linked epigenetic changes to altered gene function, shedding light on the relationship between stress and psychiatric diseases.
Researchers at Lifespan have developed a blood test that can predict a person's risk of sudden cardiac death with high accuracy, enabling more targeted and efficient assessment of patients' needs for implantable cardiac defibrillators. The test is expected to refine the need for such devices and reduce overuse of ICDs.
Research suggests that maintaining healthy blood pressure, sugar levels, and cholesterol as a young adult may help prevent cognitive decline in mid-life. A 25-year study of 3,381 participants found that those with higher risk factors scored lower on cognitive function tests in their 40s and 50s.
A study found lower risks of heart attack, death, and procedures to re-open the artery in patients receiving drug-eluting stents followed by individualized blood-thinning medication. The results challenge existing guidelines for prolonged anti-platelet therapy after stent placement.
A blood test using high-sensitivity cardiac troponin T can accurately predict heart attack risk in patients with chest pain, allowing for targeted admissions and reduced hospital costs. The test's negative predictive value was found to be 99.8 percent for heart attack within 30 days.
Physicians report success in weaning patient off bypass with intra-aortic balloon pump due to reversible left ventricle dysfunction and minimal atherosclerosis. The pump can be an option for patients with mild to moderate aortic insufficiency who don't have severe atherosclerosis.
A study found that death certificates often fail to list alcohol as a cause of death in traffic crashes, with injuries being the leading cause of death for Americans younger than 45. Researchers need reliable data to study the effects of policies aimed at reducing alcohol-related deaths.
A new stool-based screening test, Cologuard, detected 92% of colorectal cancer and 42% of advanced pre-cancerous lesions, outperforming a commercial occult blood fecal immunochemical test. The non-invasive test allows patients to collect samples at home, increasing the potential for higher cancer screening rates.
Researchers used an age-adjusted D-dimer threshold to safely exclude pulmonary embolism in elderly patients. This approach significantly reduced false positives, especially in older adults.
Scientists have identified a previously unrecognized gene variation associated with healthier blood lipid levels and reduced risk of heart attacks. The discovery uses a new approach to scan the genome for variations in genes that change protein function.
Researchers at Aarhus University found that patients with blood poisoning are twice as likely to develop a blood clot in the brain or heart. The risk is highest within 30 days of infection, and only 0.2% among the general population.
Researchers found that statins significantly reduced VTE events following total hip and knee replacements, with a 48% lower risk compared to non-statin groups. The study, which included over 400 patients, suggests that statins may have anti-inflammatory effects that contribute to their ability to decrease VTE risk.
DVT can lead to post-thrombotic syndrome, causing chronic leg pain, fatigue, swelling, and skin ulcers; interventional radiologists offer minimally invasive treatments to prevent this complication
A blood test has been developed to accurately screen for infection with the agent responsible for variant Creutzfeldt-Jakob disease. The test found 71.4% of patients with vCJD correctly tested positive, making it suitable for screening large populations.
A new therapy has been developed to treat atrial fibrillation by targeting misbehaving nerves that cause the condition. The therapy, which involves adding four or fewer injections of 98% ethanol to radio wave ablation, appears to be more effective than standard surgical therapies.
Researchers found that early but not advanced forms of atherosclerotic plaques in mice regress when 'bad' cholesterol is lowered. The study suggests that preventative cholesterol-lowering treatment could prevent more advanced plaque development and reduce the risk of stroke or heart attack.
A new scientific blood analysis uses biomarkers and NMR spectroscopy to predict short-term mortality in the next five years. The study found that biomarker concentrations are crucial for normal metabolism, regardless of known risk factors.
Researchers have identified four biomarkers in blood samples that can predict mortality from any disease within five years. The study used NMR spectroscopy to analyze over 17,000 healthy individuals and found that these biomarkers were independent of traditional risk factors, indicating a general frailty in the body.
The updated guideline recommends oral anticoagulants for people with nonvalvular atrial fibrillation to prevent stroke. The new drugs are at least as effective as established treatment and have a lower risk of bleeding, making them suitable for many previously undertreated patients.
Researchers found an antibody to KIR4.1 protein in the blood of people with multiple sclerosis (MS) years before symptoms appeared, suggesting a potential role in disease development. The study's findings may help detect MS earlier, enabling better treatment and prevention strategies.
A simple blood test can identify 85% of post-surgical heart attacks, which often go undetected due to a lack of symptoms. Heart attacks are the leading cause of death within 30 days of surgery, with 10% mortality rate.
African-Americans are 39 times more likely to die from a stroke after an infection compared to other ethnic groups. Infection promotes blood clot formation and fat buildup in arteries, contributing to higher stroke mortality rates among blacks.
Scientists have successfully engineered dermo-epidermal skin grafts that contain functional blood and lymphatic capillaries, which can rapidly supply tissue fluid and prevent accumulation. This breakthrough could improve wound healing and organ structure of these skin grafts.
Researchers discovered that valproic acid activates AMPK, which reduces fat accumulation in the liver and lowers blood sugar levels in obese mice. Treated mice showed decreased blood sugar levels and a stabilization of weight.
A study involving 186 Type II diabetes patients found that health coaching significantly improved oral health by reducing biological markers for periodontitis by 50% and long-range blood sugar levels. The coaching group also showed increased self-efficacy in handling illness and health issues.