Articles tagged with Blood
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study found that high methylation levels in the Fragile X gene are associated with increased symptoms of depression and social anxiety in women with the premutation genetic abnormality. This blood test may help diagnose individuals at risk and initiate early treatment.
A recent NIH-funded study found that HIV can genetically evolve and replicate in the brain within four months of infection, with signs of inflammation or viral replication present in up to 30% of infected patients. The study suggests that early diagnosis and treatment are crucial to prevent potential brain damage.
Researchers found that a blood test immediately after heart surgery can predict postoperative stroke risk, with elevated BUN levels being the most powerful predictor. This study aims to better assess stroke risk and reduce incidents, disabilities, and expenses.
A study by Brigham and Women's Hospital found that routine potassium monitoring for healthy women taking spironolactone for acne does not change the course of treatment, but cumulatively costs $80,000. The researchers suggest ending routine testing to improve patient care experience and reduce healthcare spending.
A new study published in the New England Journal of Medicine found that routine thrombectomy during angioplasty for heart attacks does not provide a benefit and may increase the risk of stroke. The study included over 10,000 patients and randomly assigned half to receive angioplasty alone or with manual thrombectomy.
A large study has found that routine blood clot removal during heart attack treatment does not benefit patients and may increase the risk of stroke. The TOTAL trial involved over 10,700 patients and showed no differences in cardiovascular outcomes between those who received clot removal and those who did not.
A new study by UCLA researchers has shown the feasibility of a blood-based test for diagnosing Alzheimer's disease, offering a safer and more affordable alternative to current methods. The test uses blood protein panels to predict brain amyloidosis with modest accuracy.
Researchers found Antarctic octopods have high levels of haemocyanin, a blue oxygen transport protein, in their blood. This adaptation helps them supply oxygen to tissues at sub-zero temperatures.
Researchers at the University of Copenhagen have found a correlation between high levels of vitamin D and an increased risk of cardiovascular deaths, including strokes and coronary deaths. The study suggests that levels above 100 nanomol per liter may be detrimental to health.
Recent research suggests that irisin, believed to travel from muscle to fat tissue after exercise, may not exist in humans. New tests used in previous studies found antibodies were poorly vetted and nonspecific, leading to false positive results.
A recent study found that the apixaban-amiodarone combination significantly decreased stroke risk for patients with AFib who require both heart rhythm regulation and blood thinning medication. This alternative to warfarin offers a better option for managing high-risk atrial fibrillation.
Recent articles in JBJS publications examine the relationship between bisphosphonates and atypical femoral fractures. Prodromal thigh pain, radiolucent lines on X-rays, and prolonged bisphosphonate use are indicators of an impending fracture. Conservative management with discontinuation and weight-bearing is recommended.
The new guidelines increase the proportion of AFib patients recommended for drug therapy by 19%, particularly affecting women and people over 65, who now have a lower age threshold for stroke risk assessment.
Reversing international normalized ratio (INR) below 1.3 within 4 hours and maintaining systolic blood pressure less than 160 mm Hg at 4 hours were associated with lower rates of hematoma enlargement. Resuming anticoagulant therapy was linked to a lower risk of ischemic events without increased bleeding complications.
Researchers at Houston Methodist have developed magnetic nanoparticles that can destroy blood clots 100 to 1,000 times faster than a commonly used clot-busting technique. The nanoparticles are coated in albumin and loaded with the drug tPA, allowing it to reach the clot more effectively.
Researchers developed a customized genetic construct using tiny DNA minicircles to detect cancer in mice. The technique uses a protein called secreted embryonic alkaline phosphatase, which is not produced in adults but is present in embryos.
Researchers discovered that DPP-4 inhibitors stimulate insulin production and increase glucagon levels, providing protection against hypoglycaemia in mice. This finding could lead to new areas of application for existing diabetes drugs.
Researchers developed a model to predict who stands to gain most from diabetes-preventing drugs or lifestyle changes like exercise and weight loss. The model identified seven key factors: fasting blood sugar, A1C level, triglycerides, family history of high blood sugar, waist measurement, height, and waist-to-hip ratio.
Research suggests that exercising after a meal can lower blood sugar and fat levels, providing more benefits than exercising before dinner. The study found that resistance exercise performed after dinner had the most powerful effect on reducing glucose and fat levels.
Middle-aged women who engage in regular physical activity have lower risks of heart disease, stroke, and blood clots compared to inactive counterparts. Moderate physical activity levels appear to provide the greatest reduction in risk, with more frequent activity offering little additional benefit.
Research found that patients with low vitamin D levels suffered larger areas of dead tissue resulting from obstruction of the blood supply compared to those with normal levels. Additionally, a 10 ng/mL reduction in vitamin D level was associated with a decreased chance for healthy recovery after stroke
A new biomarker in the blood has been identified that can predict the risk of developing dementia, allowing for more precise risk evaluation and earlier prevention efforts. The study involved 76,000 people and revealed a link between low levels of apolipoprotein E and increased dementia risk.
A new study by University of Pennsylvania researchers found that mosquitoes increase production of immune system proteins called leucine-rich repeat immune proteins (LRIMs) after feeding on blood, which helps fight off parasites that may be present in the blood.
Researchers developed a smartphone accessory that performs a lab-based blood test in just 15 minutes, detecting three infectious disease markers from a finger prick of blood. The device has a manufacturing cost of $34 and can be attached to any compatible smartphone for rapid diagnosis.
A large Canadian Medical Association Journal study found that combining trimethoprim-sulfamethoxazole with spironolactone more than doubles the risk of sudden death in older patients. The study suggests that physicians should consider alternative antibiotics for patients on spironolactone to reduce this risk.
The non-invasive first trimester blood test reliably detects Down syndrome in over 99% of cases, making it superior to other testing methods.
A new study finds that steroid therapy is associated with a nearly five-fold increase in venous thromboembolism events among IBD patients. Corticosteroid use was linked to a higher rate of venous thromboembolic events, even when combined with biologic therapies.
A new human study confirms that oral BPA exposure does not lead to high levels in the blood, contradicting earlier assumptions made by a dog study. The study found that the body inactivates most BPA molecules and eliminates them within 24 hours, with no evidence of accumulation.
Researchers found that mosquitoes respond weakly to human skin odor alone and require a fluctuating concentration of carbon dioxide to land on human skin. This suggests that upwind flight towards human odor may be used to locate dwellings rather than feeding sites.
A study found that both low and high blood calcium levels, as well as high phosphorus levels, are associated with an increased risk of premature death in dialysis patients. The study suggests that lowering these levels may improve patients' health, but further research is needed.
A study published in Anesthesiology found that positioning women on their side at 15 degrees does not reduce compression of the inferior vena cava as previously thought. Blood flow only partially increased at 30 degrees, challenging the long-held practice of tilting hips during labor.
Researchers at UCLA have found that a deficiency of the hormone hepcidin makes people with iron overload disease susceptible to Vibrio vulnificus infections. A medical form of hepcidin, minihepcidin, has been shown to cure the infection by restricting bacterial growth.
Researchers found a higher blood volume shift from the lower to upper body due to weightlessness, with lower blood pressure than anticipated. Blood pressure decreased by 10 mmHg, similar to high blood pressure medication, during long-duration spaceflight.
A new study in mice suggests that a blood-based biomarker for traumatic brain injury (TBI) may not be effective due to the complex glymphatic system. The researchers found that treatments and clinical approaches can disrupt waste removal, leading to unreliable protein levels in the blood.
A study published in Clinical Infectious Diseases demonstrated the pivotal data for T2Candida and T2Dx, detecting Candida species with 91.1% sensitivity and 99.4% specificity in 3-5 hours without blood culture. This technology has the potential to reduce costs, length of stay, and mortality rates associated with Candida infections.
Researchers developed a new scoring system to predict graft vs. host disease (GVHD) severity in bone marrow transplant patients. The Ann Arbor GVHD score uses biomarkers to determine treatment intensity and identify patients who may not respond to standard therapy.
Researchers have discovered that small changes in blood acidity can lead to inaccurate calcium level monitoring, resulting in higher PTH levels and increased risk of artery damage. This affects patients with chronic kidney disease, who already face a high risk of fatal calcification.
A study of over 80,000 women found a significant association between specific ABO blood groups and an increased risk of type 2 diabetes. Those with blood groups A, B, and AB had a higher risk compared to individuals with group O blood.
Researchers found that postoperative TRALI is significantly underreported but occurs in 1.4 percent of surgical patients, while TACO remains a risk at 4 percent, particularly in those with increased volume of blood transfused and advanced age. The studies provide new insights into the incidence of these life-threatening complications.
A new study suggests that measuring glial fibrillary acidic protein (GFAP) in the blood can predict the presence of intracranial lesions following mild traumatic brain injury. The study found GFAP to be a more reliable biomarker than S100β, which was not as effective in distinguishing between intracranial and extracranial lesions.
A new study shows racial disparities in Medicare Advantage persist across the US, except in Western states, where control of key health measures is higher for black seniors. In contrast, Eastern and Midwestern states show significant gaps between white and black seniors.
Researchers identified rare APOA5 gene mutations linked to high triglycerides and increased heart attack risk. The study found that these mutations also raise LDL receptor mutation prevalence, underscoring the role of triglyceride metabolism in early-onset heart attacks.
Researchers at UC Berkeley have developed a new organic optoelectronic sensor that can accurately measure blood-oxygen levels and is thin, flexible, and disposable. The device uses red and green light to detect changes in oxygen saturation levels, making it potentially cheaper and more convenient than conventional pulse oximeters.
A new Rutgers-led research study found that patients with heart disease who receive transfusions during surgeries do just as well with smaller amounts of blood. The study measured overall mortality and found no evidence of increased mortality from cardiovascular disease or severe infection due to the amount of blood given after surgery.
A new study published in PLOS Medicine found that even within the normal BMI range, excess fat has a negative impact on cardiometabolic risk markers. The researchers used Mendelian randomization to assess the effect of BMI increases on metabolic abnormalities in 12,664 young adults.
Researchers identified a modified host protein as a potential risk factor for plasma cell dyscrasis. Individuals with high levels of SUMO-modified HSP90 are at increased risk of developing multiple myeloma and other related diseases.
A study of over 1.4 million patients found that longer surgical procedures are associated with a higher risk of developing blood clots, including deep vein thrombosis and pulmonary embolism. The study also identified three common procedures as risk factors for blood clots.
A world-first breakthrough drug therapy for treating battle casualties is being developed by James Cook University scientists in Australia, with potential to save thousands of soldiers' lives and has widespread civilian applications.
Research suggests that spices and herbs, such as cinnamon and garlic, can lower triglyceride levels in the blood, which can lead to a reduced risk of heart disease. The use of high-antioxidant spice blends may be a potential way to reduce calorie intake without sacrificing flavor.
A new study found that offering a $50 cash reward through a lottery-style incentive increased the completion rate of stool tests for colon cancer screening among veterans. The test helps detect early signs of abnormal growths or cancer in the colon and is recommended annually for people over 50.
Researchers have identified a new protein, THSD7A, that turns the immune system against itself in kidney disease called membranous nephropathy (MN). This discovery enables the development of a blood test to diagnose MN, which can reduce the need for kidney biopsies by up to 85%.
A specialized ambulance staffed with a neurologist and equipped with a computed tomographic scanner increased the percentage of stroke patients receiving thrombolysis within the golden hour, reducing time to treatment by 24.5 minutes. This approach improved short-term outcomes without increasing risks for mortality.
The UCI team has created a new technology called Integrated Comprehensive Droplet Digital Detection (IC 3D) that can detect bacterial invaders in blood samples with unprecedented speed and accuracy. In as little as 90 minutes, IC 3D can identify bacteria at single-cell sensitivity without the need for cell culture.
The PRESERVE study aims to determine the safety and effectiveness of IVC filters in preventing pulmonary embolism. It will enroll 2,100 patients at over 60 centers across the US and assess patient outcomes every six months for up to two years.
A Queensland University of Technology study found that over 70% of people in two Chinese cities are unaware of the blood alcohol limits for driving. The new laws have led to a drop in alcohol-related crashes, but limited awareness may contribute to offending rates.
A study by Linköping University found that a single compound in blood, trans-4,5-epoxy-(E)-2-decenal, is as attractive to large carnivores as the entire blood smell. Researchers discovered this through gas chromatography and mass spectrometry techniques.
Researchers found that elderly men with low DHEA levels were at a greater risk of developing coronary heart disease events over a five-year period. The study suggests that high DHEA levels may be a biomarker of good health in elderly men.
Researchers at the University of California, San Diego, propose a new surgical intervention that combines the first and second steps of single-ventricle heart surgery. This approach aims to reduce the workload on the patient's heart, increase blood flow to the lungs, and improve oxygen delivery.
Researchers at Stanford University School of Medicine have found a direct link between oxytocin levels in blood and cerebrospinal fluid and anxiety. Low oxytocin levels are correlated with high anxiety scores, suggesting that oxytocin may be a biomarker for anxiety and a potential therapeutic target.
Patients with atrial fibrillation taking dabigatran are at a higher risk of major and gastrointestinal bleeding compared to warfarin users. The study found that African-Americans and patients with chronic kidney disease were more likely to experience major bleeds.