Articles tagged with Blood
A new study suggests that measuring glial fibrillary acidic protein (GFAP) in the blood can predict the presence of intracranial lesions following mild traumatic brain injury. The study found GFAP to be a more reliable biomarker than S100β, which was not as effective in distinguishing between intracranial and extracranial lesions.
Researchers identified rare APOA5 gene mutations linked to high triglycerides and increased heart attack risk. The study found that these mutations also raise LDL receptor mutation prevalence, underscoring the role of triglyceride metabolism in early-onset heart attacks.
Researchers at UC Berkeley have developed a new organic optoelectronic sensor that can accurately measure blood-oxygen levels and is thin, flexible, and disposable. The device uses red and green light to detect changes in oxygen saturation levels, making it potentially cheaper and more convenient than conventional pulse oximeters.
A new Rutgers-led research study found that patients with heart disease who receive transfusions during surgeries do just as well with smaller amounts of blood. The study measured overall mortality and found no evidence of increased mortality from cardiovascular disease or severe infection due to the amount of blood given after surgery.
A new study shows racial disparities in Medicare Advantage persist across the US, except in Western states, where control of key health measures is higher for black seniors. In contrast, Eastern and Midwestern states show significant gaps between white and black seniors.
A new study published in PLOS Medicine found that even within the normal BMI range, excess fat has a negative impact on cardiometabolic risk markers. The researchers used Mendelian randomization to assess the effect of BMI increases on metabolic abnormalities in 12,664 young adults.
Researchers identified a modified host protein as a potential risk factor for plasma cell dyscrasis. Individuals with high levels of SUMO-modified HSP90 are at increased risk of developing multiple myeloma and other related diseases.
A study of over 1.4 million patients found that longer surgical procedures are associated with a higher risk of developing blood clots, including deep vein thrombosis and pulmonary embolism. The study also identified three common procedures as risk factors for blood clots.
A world-first breakthrough drug therapy for treating battle casualties is being developed by James Cook University scientists in Australia, with potential to save thousands of soldiers' lives and has widespread civilian applications.
Research suggests that spices and herbs, such as cinnamon and garlic, can lower triglyceride levels in the blood, which can lead to a reduced risk of heart disease. The use of high-antioxidant spice blends may be a potential way to reduce calorie intake without sacrificing flavor.
Researchers have identified a new protein, THSD7A, that turns the immune system against itself in kidney disease called membranous nephropathy (MN). This discovery enables the development of a blood test to diagnose MN, which can reduce the need for kidney biopsies by up to 85%.
A specialized ambulance staffed with a neurologist and equipped with a computed tomographic scanner increased the percentage of stroke patients receiving thrombolysis within the golden hour, reducing time to treatment by 24.5 minutes. This approach improved short-term outcomes without increasing risks for mortality.
A new study found that offering a $50 cash reward through a lottery-style incentive increased the completion rate of stool tests for colon cancer screening among veterans. The test helps detect early signs of abnormal growths or cancer in the colon and is recommended annually for people over 50.
The UCI team has created a new technology called Integrated Comprehensive Droplet Digital Detection (IC 3D) that can detect bacterial invaders in blood samples with unprecedented speed and accuracy. In as little as 90 minutes, IC 3D can identify bacteria at single-cell sensitivity without the need for cell culture.
The PRESERVE study aims to determine the safety and effectiveness of IVC filters in preventing pulmonary embolism. It will enroll 2,100 patients at over 60 centers across the US and assess patient outcomes every six months for up to two years.
A study by Linköping University found that a single compound in blood, trans-4,5-epoxy-(E)-2-decenal, is as attractive to large carnivores as the entire blood smell. Researchers discovered this through gas chromatography and mass spectrometry techniques.
Researchers found that elderly men with low DHEA levels were at a greater risk of developing coronary heart disease events over a five-year period. The study suggests that high DHEA levels may be a biomarker of good health in elderly men.
A Queensland University of Technology study found that over 70% of people in two Chinese cities are unaware of the blood alcohol limits for driving. The new laws have led to a drop in alcohol-related crashes, but limited awareness may contribute to offending rates.
Researchers at the University of California, San Diego, propose a new surgical intervention that combines the first and second steps of single-ventricle heart surgery. This approach aims to reduce the workload on the patient's heart, increase blood flow to the lungs, and improve oxygen delivery.
Researchers at Stanford University School of Medicine have found a direct link between oxytocin levels in blood and cerebrospinal fluid and anxiety. Low oxytocin levels are correlated with high anxiety scores, suggesting that oxytocin may be a biomarker for anxiety and a potential therapeutic target.
Patients with atrial fibrillation taking dabigatran are at a higher risk of major and gastrointestinal bleeding compared to warfarin users. The study found that African-Americans and patients with chronic kidney disease were more likely to experience major bleeds.
A team of UBC researchers has developed a synthetic antidote that can reverse the effects of all types of heparin used in clinics. The breakthrough has significant implications for cardiothoracic surgery and anticoagulant-related bleeding problems.
A recent study found that robotically assisted coronary artery bypass grafting (CABG) surgery is a safe and feasible alternative to traditional bypass surgery, reducing complications and hospital stays. The procedure uses robotic precision to perform precise incisions with less blood loss and cosmetic scarring.
A new blood test has been developed to diagnose early onset Alzheimer's disease, detecting changes in the brain two decades before symptoms appear. The test shows high accuracy in predicting AD risk and has the potential to improve treatment options.
Researchers at the University of Washington have developed an iPhone app called BiliCam to determine the severity of jaundice in newborns without drawing blood. The app has the potential to improve healthcare in the US and save thousands of lives in low-resource countries.
Researchers found that shutting off blood supply to an arm or leg before cardiac surgery reduces heart muscle energy production and activates protective protein Akt. This technique, called RIPC, has the potential to protect the heart during future cardiac surgeries.
Researchers at UBC have developed a novel method to test for vitamin B12 deficiency, which can be done with just one drop of blood. The new method is sensitive enough to detect B12 levels in newborn babies and large populations, offering a convenient alternative to traditional blood tests.
Research at the University of Missouri discovered that thermal paper receipts from cash registers are a significant source of bisphenol A (BPA) in humans. The study found that subjects who handled thermal paper and then touched their faces or food experienced rapid BPA absorption, leading to high blood levels.
A study found that thermal receipt paper can transfer high amounts of BPA to hands and blood levels after handling, particularly in women. This raises concerns about the potential health risks associated with prolonged exposure to BPA through daily activities.
Researchers at Emory University School of Medicine have identified a protein called urokinase-type plasminogen activator or uPA that helps brain cells recover from injuries induced by loss of blood flow. The study found that treating mice with uPA after an experimental stroke can improve their recovery of motor function.
A new agent has been developed to treat overdoses using peritoneal dialysis, which can extract up to a hundred times more toxins from the body than conventional alternatives. This method is especially effective for treating serious liver disease, including cases involving ammonia accumulation in the blood.
The Surgical Trauma Series examines the biological mechanisms and clinical implications of large-scale trauma. Researchers discuss the systemic immune response to trauma, its association with reduced resistance to infection, and the role of ageing in influencing survival rates.
Researchers at Kansas State University discovered a protein in caterpillar blood that helps insects detect fungal infections and trigger immune responses. The findings may lead to new ways to control disease transmission from insects to humans and animals, as well as novel methods for biocontrol of agricultural insect pests.
Annual incidences of venous thromboembolism range from 0.75 to 2.69 per 1,000 individuals globally. Hospital-acquired cases contribute significantly to years lost due to ill-health.
A new technique called slug flow microextraction allows for the quick detection of drugs and monitoring of medical conditions using only a small sample of biological fluid. The method involves extracting target molecules from the sample and analyzing them with mass spectrometry, resulting in results in just minutes.
Researchers found that high-sensitivity troponin T and N-terminal pro-B-type natriuretic peptide levels strongly predict heart failure in individuals with mild to severe kidney disease. These biomarkers may indicate subclinical cardiovascular changes, contributing to the development of heart failure.
Researchers found that Montmorency tart cherry juice lowered blood uric acid levels and increased specific anthocyanin compounds, which may help alleviate joint pain and inflammation associated with conditions like gout. The study also detected increased C-reactive protein in the bloodstream after consuming tart cherries.
Researchers found that oleate, a common dietary fat, restored proper metabolism of fuel in an animal model of heart failure. This improvement enabled the heart muscle to access energy more efficiently and reduced toxic fatty byproducts.
Biennial colorectal cancer screening in France's Cote-D'Or region increased the rate of diagnosis of high-risk pre-cancerous adenomas by 89%. The study also found that fecal occult blood testing may be more efficient than colonoscopy for high-risk patients.
A new blood test identifies 9 RNA markers tied to depression, predicting who will benefit from therapy and providing the first objective, scientific diagnosis. The test also shows biological effects of cognitive behavioral therapy, offering personalized medicine approach to people suffering from depression.
A new study has provided clinical guidelines for selecting the best oral blood thinner for patients suffering from deep vein thrombosis. The study, published in JAMA, analyzed 45 randomized trials involving nearly 45,000 patients and found no major differences in effectiveness and safety among eight anticoagulant therapies.
Researchers have identified a novel drug target, Kir7.1, that induces acute and sustained uterine contractions to treat postpartum haemorrhage (PPH), a major global cause of maternal mortality. The treatment bypasses biochemical pathways exhausted during prolonged labour, promising effective treatment at low doses.
Research on Korean adults finds that prolonged work hours are linked to a higher risk of developing coronary heart disease. Employees working 61-80 hours per week face a 42-94% increased likelihood of disease development within 10 years.
The biospleen device uses magnetic beads coated with genetically engineered MBL proteins to remove pathogens and toxins from the blood. In laboratory tests, it filtered out over 90% of key sepsis pathogens within five hours.
A new app-device can quickly and accurately measure two key signs of sepsis, a leading cause of death worldwide. The device has the potential to save over 6 million children in developing countries, where sepsis accounts for 60-80% of all deaths.
A recent study found that individuals with blood type AB are 82% more likely to develop cognitive impairment and dementia than those with other blood types. High levels of factor VIII, a protein related to clotting, were also linked to increased risk of memory problems.
A new study uses genetically modified plants to teach the immune system to tolerate clotting factors, reducing the risk of antibody formation. The treatment, which involves feeding mice with plant capsules, has shown promising results and may offer a cost-effective alternative to current treatments.
A new study found lower testosterone levels in men with sudden cardiac arrest and higher estradiol levels in both men and women were associated with increased risk. The research suggests that hormone levels may play a role in predicting patients' likelihood of suffering from the usually fatal condition.
Researchers found that contaminated blood cultures can serve as diagnostic predictors for more targeted antibiotics. The study showed that highly resistant skin germs could indicate high mortality rates for the actual disease-causing bacteria.
A new study published in Circulation found that low-dose aspirin significantly reduces the risk of new venous blood clots and cardiovascular events. The treatment is especially useful for patients who cannot take long-term anticoagulant medications due to expense or bleeding risks.
Researchers found that Deformed Wing Virus (DWV) is the most affected virus species by Varroa infestation, while Kashmir Bee Virus (KBV) peaks two years after initial infestation and disappears. The study highlights the importance of beekeeper awareness, mite monitoring, and efficient Varroa control.
Researchers found MSCs in patient's blood after severe trauma, suggesting they are released from bone marrow into bloodstream following organ damage. The study provides conclusive evidence for the mobilization and migration of MSCs in humans.
Researchers have identified a 52-character biological signal specific to bacterial infection in newborns' DNA, enabling early detection and diagnosis. This breakthrough could lead to the development of a single-drop blood test, limiting antibiotic overuse and tackling drug resistance.
A study found that delaying cardioversion for more than 12 hours after atrial fibrillation diagnosis increases the risk of strokes and blood clots. Patients with delayed treatment had a higher incidence of thromboembolic complications, highlighting the importance of prompt correction.
Severely overweight patients with hypoventilation can experience low blood oxygen levels during air travel. Experts recommend a pre-flight hypoxic challenge test for better preparedness and potential use of supplemental oxygen or non-invasive ventilation.
Physicians at Johns Hopkins have developed blood and saliva tests that accurately predict the recurrence of HPV-linked oral cancers. The tests screen for DNA fragments of the human papillomavirus shed from cancer cells, with accuracy rates of up to 70% in some patients.
Researchers from University of Southern Denmark and Aarhus University have discovered how the PAI-1 protein behaves, revealing a unique shape change mechanism. This knowledge allows for better control over coagulation, reducing risk of bleeding or blood clots.
A hospital used the ACS NSQIP database to identify a link between postoperative isolation and increased risk of venous thromboembolism. By implementing measures such as designated ambulation areas and spirometer use, the hospital was able to reduce VTE rates and save an estimated $10,000 to $16,000 per potentially affected patient.
A new study led by Dr. Marc Rodger finds that low molecular weight heparin (LMWH) has no positive benefits for pregnant women, and may even cause harm by increasing bleeding and reducing access to anesthesia during childbirth. The study's results are a significant relief for many women who had been prescribed the treatment for decades.
A new analysis compares various anticoagulants after different types of orthopedic surgery. Aspirin may be a suitable option for preventing blood clots in patients undergoing hip or knee replacements, but anticoagulation therapy is more beneficial for those who have undergone hip fracture repairs.