Articles tagged with Blood
The PRESERVE study aims to determine the safety and effectiveness of IVC filters in preventing pulmonary embolism. It will enroll 2,100 patients at over 60 centers across the US and assess patient outcomes every six months for up to two years.
A Queensland University of Technology study found that over 70% of people in two Chinese cities are unaware of the blood alcohol limits for driving. The new laws have led to a drop in alcohol-related crashes, but limited awareness may contribute to offending rates.
A study by Linköping University found that a single compound in blood, trans-4,5-epoxy-(E)-2-decenal, is as attractive to large carnivores as the entire blood smell. Researchers discovered this through gas chromatography and mass spectrometry techniques.
Researchers found that elderly men with low DHEA levels were at a greater risk of developing coronary heart disease events over a five-year period. The study suggests that high DHEA levels may be a biomarker of good health in elderly men.
Researchers at the University of California, San Diego, propose a new surgical intervention that combines the first and second steps of single-ventricle heart surgery. This approach aims to reduce the workload on the patient's heart, increase blood flow to the lungs, and improve oxygen delivery.
Researchers at Stanford University School of Medicine have found a direct link between oxytocin levels in blood and cerebrospinal fluid and anxiety. Low oxytocin levels are correlated with high anxiety scores, suggesting that oxytocin may be a biomarker for anxiety and a potential therapeutic target.
Patients with atrial fibrillation taking dabigatran are at a higher risk of major and gastrointestinal bleeding compared to warfarin users. The study found that African-Americans and patients with chronic kidney disease were more likely to experience major bleeds.
A team of UBC researchers has developed a synthetic antidote that can reverse the effects of all types of heparin used in clinics. The breakthrough has significant implications for cardiothoracic surgery and anticoagulant-related bleeding problems.
A recent study found that robotically assisted coronary artery bypass grafting (CABG) surgery is a safe and feasible alternative to traditional bypass surgery, reducing complications and hospital stays. The procedure uses robotic precision to perform precise incisions with less blood loss and cosmetic scarring.
A new blood test has been developed to diagnose early onset Alzheimer's disease, detecting changes in the brain two decades before symptoms appear. The test shows high accuracy in predicting AD risk and has the potential to improve treatment options.
Researchers at the University of Washington have developed an iPhone app called BiliCam to determine the severity of jaundice in newborns without drawing blood. The app has the potential to improve healthcare in the US and save thousands of lives in low-resource countries.
Researchers found that shutting off blood supply to an arm or leg before cardiac surgery reduces heart muscle energy production and activates protective protein Akt. This technique, called RIPC, has the potential to protect the heart during future cardiac surgeries.
Researchers at UBC have developed a novel method to test for vitamin B12 deficiency, which can be done with just one drop of blood. The new method is sensitive enough to detect B12 levels in newborn babies and large populations, offering a convenient alternative to traditional blood tests.
Research at the University of Missouri discovered that thermal paper receipts from cash registers are a significant source of bisphenol A (BPA) in humans. The study found that subjects who handled thermal paper and then touched their faces or food experienced rapid BPA absorption, leading to high blood levels.
A study found that thermal receipt paper can transfer high amounts of BPA to hands and blood levels after handling, particularly in women. This raises concerns about the potential health risks associated with prolonged exposure to BPA through daily activities.
Researchers at Emory University School of Medicine have identified a protein called urokinase-type plasminogen activator or uPA that helps brain cells recover from injuries induced by loss of blood flow. The study found that treating mice with uPA after an experimental stroke can improve their recovery of motor function.
A new agent has been developed to treat overdoses using peritoneal dialysis, which can extract up to a hundred times more toxins from the body than conventional alternatives. This method is especially effective for treating serious liver disease, including cases involving ammonia accumulation in the blood.
The Surgical Trauma Series examines the biological mechanisms and clinical implications of large-scale trauma. Researchers discuss the systemic immune response to trauma, its association with reduced resistance to infection, and the role of ageing in influencing survival rates.
Researchers at Kansas State University discovered a protein in caterpillar blood that helps insects detect fungal infections and trigger immune responses. The findings may lead to new ways to control disease transmission from insects to humans and animals, as well as novel methods for biocontrol of agricultural insect pests.
Annual incidences of venous thromboembolism range from 0.75 to 2.69 per 1,000 individuals globally. Hospital-acquired cases contribute significantly to years lost due to ill-health.
A new technique called slug flow microextraction allows for the quick detection of drugs and monitoring of medical conditions using only a small sample of biological fluid. The method involves extracting target molecules from the sample and analyzing them with mass spectrometry, resulting in results in just minutes.
Researchers found that high-sensitivity troponin T and N-terminal pro-B-type natriuretic peptide levels strongly predict heart failure in individuals with mild to severe kidney disease. These biomarkers may indicate subclinical cardiovascular changes, contributing to the development of heart failure.
Researchers found that Montmorency tart cherry juice lowered blood uric acid levels and increased specific anthocyanin compounds, which may help alleviate joint pain and inflammation associated with conditions like gout. The study also detected increased C-reactive protein in the bloodstream after consuming tart cherries.
Researchers found that oleate, a common dietary fat, restored proper metabolism of fuel in an animal model of heart failure. This improvement enabled the heart muscle to access energy more efficiently and reduced toxic fatty byproducts.
Biennial colorectal cancer screening in France's Cote-D'Or region increased the rate of diagnosis of high-risk pre-cancerous adenomas by 89%. The study also found that fecal occult blood testing may be more efficient than colonoscopy for high-risk patients.
A new study has provided clinical guidelines for selecting the best oral blood thinner for patients suffering from deep vein thrombosis. The study, published in JAMA, analyzed 45 randomized trials involving nearly 45,000 patients and found no major differences in effectiveness and safety among eight anticoagulant therapies.
A new blood test identifies 9 RNA markers tied to depression, predicting who will benefit from therapy and providing the first objective, scientific diagnosis. The test also shows biological effects of cognitive behavioral therapy, offering personalized medicine approach to people suffering from depression.
Researchers have identified a novel drug target, Kir7.1, that induces acute and sustained uterine contractions to treat postpartum haemorrhage (PPH), a major global cause of maternal mortality. The treatment bypasses biochemical pathways exhausted during prolonged labour, promising effective treatment at low doses.
Research on Korean adults finds that prolonged work hours are linked to a higher risk of developing coronary heart disease. Employees working 61-80 hours per week face a 42-94% increased likelihood of disease development within 10 years.
The biospleen device uses magnetic beads coated with genetically engineered MBL proteins to remove pathogens and toxins from the blood. In laboratory tests, it filtered out over 90% of key sepsis pathogens within five hours.
A new app-device can quickly and accurately measure two key signs of sepsis, a leading cause of death worldwide. The device has the potential to save over 6 million children in developing countries, where sepsis accounts for 60-80% of all deaths.
A recent study found that individuals with blood type AB are 82% more likely to develop cognitive impairment and dementia than those with other blood types. High levels of factor VIII, a protein related to clotting, were also linked to increased risk of memory problems.
A new study uses genetically modified plants to teach the immune system to tolerate clotting factors, reducing the risk of antibody formation. The treatment, which involves feeding mice with plant capsules, has shown promising results and may offer a cost-effective alternative to current treatments.
A new study found lower testosterone levels in men with sudden cardiac arrest and higher estradiol levels in both men and women were associated with increased risk. The research suggests that hormone levels may play a role in predicting patients' likelihood of suffering from the usually fatal condition.
Researchers found that contaminated blood cultures can serve as diagnostic predictors for more targeted antibiotics. The study showed that highly resistant skin germs could indicate high mortality rates for the actual disease-causing bacteria.
A new study published in Circulation found that low-dose aspirin significantly reduces the risk of new venous blood clots and cardiovascular events. The treatment is especially useful for patients who cannot take long-term anticoagulant medications due to expense or bleeding risks.
Researchers found that Deformed Wing Virus (DWV) is the most affected virus species by Varroa infestation, while Kashmir Bee Virus (KBV) peaks two years after initial infestation and disappears. The study highlights the importance of beekeeper awareness, mite monitoring, and efficient Varroa control.
Researchers found MSCs in patient's blood after severe trauma, suggesting they are released from bone marrow into bloodstream following organ damage. The study provides conclusive evidence for the mobilization and migration of MSCs in humans.
Researchers have identified a 52-character biological signal specific to bacterial infection in newborns' DNA, enabling early detection and diagnosis. This breakthrough could lead to the development of a single-drop blood test, limiting antibiotic overuse and tackling drug resistance.
A study found that delaying cardioversion for more than 12 hours after atrial fibrillation diagnosis increases the risk of strokes and blood clots. Patients with delayed treatment had a higher incidence of thromboembolic complications, highlighting the importance of prompt correction.
Severely overweight patients with hypoventilation can experience low blood oxygen levels during air travel. Experts recommend a pre-flight hypoxic challenge test for better preparedness and potential use of supplemental oxygen or non-invasive ventilation.
Physicians at Johns Hopkins have developed blood and saliva tests that accurately predict the recurrence of HPV-linked oral cancers. The tests screen for DNA fragments of the human papillomavirus shed from cancer cells, with accuracy rates of up to 70% in some patients.
Researchers from University of Southern Denmark and Aarhus University have discovered how the PAI-1 protein behaves, revealing a unique shape change mechanism. This knowledge allows for better control over coagulation, reducing risk of bleeding or blood clots.
A hospital used the ACS NSQIP database to identify a link between postoperative isolation and increased risk of venous thromboembolism. By implementing measures such as designated ambulation areas and spirometer use, the hospital was able to reduce VTE rates and save an estimated $10,000 to $16,000 per potentially affected patient.
A new study led by Dr. Marc Rodger finds that low molecular weight heparin (LMWH) has no positive benefits for pregnant women, and may even cause harm by increasing bleeding and reducing access to anesthesia during childbirth. The study's results are a significant relief for many women who had been prescribed the treatment for decades.
A new analysis compares various anticoagulants after different types of orthopedic surgery. Aspirin may be a suitable option for preventing blood clots in patients undergoing hip or knee replacements, but anticoagulation therapy is more beneficial for those who have undergone hip fracture repairs.
Researchers at Saint Louis University discovered that deleting disordered sections of a protein's structure reveals the molecular mechanism of blood clotting. By crystallizing prothrombin, they found that the deleted version is activated to thrombin faster and provides key information on the mechanism of prothrombin activation.
Researchers found that blood clots are rare in children undergoing spine operations, and most patients can be safely monitored without anti-clotting medication. High-risk groups include children with congenital scoliosis or spinal curvatures part of a syndrome, as well as older children.
Researchers from UCL and the Mayo Clinic argue that labelling people with moderately high blood sugar as pre-diabetic has no health benefits. The term could create significant burdens on healthcare systems without conferring any long-term health benefits.
A recent study of over 500,000 Danish women found no increased risk of venous thromboembolism following quadrivalent HPV vaccination. The research, published in JAMA, used data from national registers to evaluate the potential link between the vaccine and blood clots.
A study by Brown University researchers found that Rhode Island's Lead Hazard Mitigation Law has significantly reduced blood lead levels in children living in compliant buildings. However, only 20% of properties covered by the law were in compliance, with average lead levels still above 5 micrograms per deciliter in noncompliant homes.
A recent study found that even low levels of lead in children's blood are associated with increased risk of behavioral and emotional problems. As blood lead levels increase, so do the problems, highlighting the importance of reducing lead exposure in children.
A study of Chinese preschoolers found associations between moderately elevated blood lead concentrations and teacher-reported behavioral problems. The study suggests that further examination is needed to clarify the biological effects of environmental lead exposure on children's behavior.
Researchers found that people with a specific gene variation have lower blood lipids and a reduced risk of arteriosclerosis. The study, based on two large population studies, suggests that inhibiting apolipoprotein C3 could be an effective target for new drugs to prevent cardiovascular disease.
Researchers discovered four rare APOC3 gene mutations that lower blood triglyceride levels and reduce the risk of coronary artery disease by 40%. The study suggests a powerful strategy for developing new drugs against heart disease.
Researchers developed biomarkers from whole blood gene expression profiles to predict disease status at 12 months in children with newly diagnosed JIA. The study found strong predictive properties for disease status after four months of therapy, and identified different mechanisms of response in RF positive patients.
A new assay can detect toxic prions in blood samples from humans with variant Creutzfeldt-Jakob Disease (vCJD) and asymptomatic animals. The test, developed by French researchers, was tested on vCJD patients and non-infected controls, accurately identifying infected individuals.
Researchers found that persons with lower blood vitamin D levels were twice as likely to die prematurely as those with higher levels, regardless of bone disease risks. The study supports previous findings on low vitamin D being hazardous and provides reassurance on safe dosing up to 4,000 IU/day.
A recent study found that frequent use of permanent dyes and perming treatments may expose hairdressers to banned aromatic amines, linked to increased cancer risk. The researchers recommend protective measures such as wearing gloves to minimize skin exposure.
Researchers at Mount Sinai Hospital discovered that a protein called Sirtuin1 (SIRT1) is essential for maintaining healthy aging of blood stem cells. The study found that loss of SIRT1 leads to impaired regeneration and resembles aged, defective stem cells in mouse models.