Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
Researchers at McMaster University have developed an antidote that reverses the effects of two new blood thinners, apixaban and rivaroxaban, within minutes. This breakthrough may help save lives by quickly reversing bleeding complications in emergency situations.
A new study found that short bursts of high-intensity exercise improved cholesterol, blood sugar, and weight among Type 2 diabetes patients. Researchers compared the effects of 30 minutes of lower-intensity exercise to three months of high-intensity exercise in 10-minute bursts, finding a significant difference in outcomes.
Researchers found that individuals with better blood sugar control after consuming barley kernel bread had a different balance of gut microbes. The study suggests the importance of individualized dietary guidelines based on gut microbiota. Further studies are planned to confirm the findings and develop combination products with Prevote...
Scientists found that asymptomatic people can infect mosquitoes with dengue virus, representing three-quarters of all dengue infections. This challenges existing theories and highlights the potential for these individuals to contribute to the spread of the virus.
Researchers are developing a simple, inexpensive blood test that can detect the risk of Alzheimer's disease in individuals with Down syndrome. The test aims to identify people who will develop the disease before cognitive symptoms appear.
The FIGHT study found that liraglutide, a type-2 diabetes drug, did not improve the clinical stability or pumping action of the heart in patients with advanced heart failure. Researchers discovered no significant favorable effects of liraglutide on heart function or quality of life among participants.
A new blood test has been developed to detect foetal blood group, sex, and genetic conditions in unborn babies with high accuracy. The test is non-invasive and costs a fraction of traditional amniocentesis tests.
A lack of sufficient sleep reduces the body's sensitivity to insulin, impairing blood sugar regulation and increasing diabetes risk. The study found that insufficient sleep impairs insulin sensitivity, leading to a reduced ability to regulate blood sugar levels.
Italian scientists discover higher blood levels of zonulin in patients with non-coeliac gluten sensitivity (NCGS) and irritable bowel syndrome (IBS), suggesting a role for the protein in developing these conditions. The findings may lead to new treatment strategies for NCGS and IBS.
A pharmacy-led glycemic control program is linked to improved outcomes for surgical patients with diabetes, including fewer complications and readmissions. Patients in the program had better blood sugar control, reduced hospital readmissions, and lower medical costs.
Researchers found that fitter men performed better mentally than less fit men by using parts of their brains in the same way as in their youth. Aerobic fitness was associated with higher left-PFC activity and faster reaction times, indicating older adults who use a more youth-like brain perform better.
Researchers at the University of South Carolina have developed a new technique called 'steam thermography' that can detect blood spots in crime scenes more effectively than luminol. The method uses thermal imaging and a hand steamer to highlight where blood is present, even in highly diluted samples.
A large registry study of almost 50,000 patients in Sweden found that transfusion with stored blood does not influence patient outcomes after heart surgery. The study provides firm reassurance that current blood storage practices are safe.
Researchers at UCSB have discovered a mechanism by which secreted proteins age and turn over, shedding light on a crucial aspect of health and disease. The discovery identifies over 600 proteins with molecular signs of aging and turnover, including regulators of proteolysis, blood coagulation, and immunity.
A team of researchers at the University of Virginia Health System is exploring the link between glucose metabolism and heart function. They aim to identify a therapeutic window where intervention can prevent cardiac dysfunction and subsequent heart failure.
Scripps Health cardiology experts will share leading-edge techniques for improving heart care during the annual Transcatheter Cardiovascular Therapeutics (TCT) symposium. Matthew Price, M.D., will present on the WATCHMAN left atrial appendage closure device, an alternative to blood thinners for stroke prevention.
Researchers found that people with a common genetic variant in MTNR1B may be more at risk for developing type 2 diabetes when taking melatonin close to mealtimes. The study suggests that genetics can impact blood sugar control, highlighting the need for caution when taking melatonin near meal times.
A new study from the Cedars-Sinai Heart Institute shows that about 15% of patients with bioprosthetic aortic heart valves develop blood clots on the leaflets, which can impair valve motion. However, anti-coagulation medications like Warfarin quickly resolve the issue for all patients, regardless of the type of valve or procedure.
Researchers at the University of British Columbia have created a self-propelled powder that can deliver coagulants against severe blood flow to treat trauma-related bleeding. The innovative particles use gas-generating calcium carbonate micro-particles to propel clotting agents deep into damaged tissue.
Researchers found that sedentary time was associated with higher risks of heart and diabetes problems, regardless of exercise levels. The study suggests that reducing sedentary time can be beneficial for Hispanic adults' overall health.
A new treatment involving the removal of a protein called sFlt-1 from the blood has shown promise in prolonging pregnancy in women with preeclampsia. Pregnancy continued for an average of 8 days and 15 days in treated women, compared to just 3 days in untreated women.
Researchers at the University of Montreal developed rapid and inexpensive medical diagnostic tests using DNA molecules. The new technology detects protein markers linked to various diseases and can be used to build point-of-care devices for quick medical diagnosis, potentially impacting global health.
A Phase 2 open-label study found that brentuximab vedotin achieved a high response rate, including complete remissions, in older Hodgkin lymphoma patients unfit for chemotherapy. The treatment was generally well-tolerated, with peripheral sensory neuropathy being the most common adverse event.
Researchers found that intoxication and distractions further impair driving abilities, even at low blood alcohol levels. The study suggests reducing the legal limit may not be enough to ensure safe driving.
Research found that gut bacteria contribute to differences in body fat (BMI), blood lipids such as triglycerides and HDL, but have little relationship with bad cholesterol. The study used deep sequencing technology to identify 34 types of bacteria associated with these changes.
Researchers found a new biomarker in ceramides that may help diagnose and treat episodic migraine. Women with episodic migraine had lower levels of ceramides in their blood compared to those without headaches.
A new review presents a patient-specific plan to predict blood loss and address it, highlighting the commonality of anemia in surgical practice. The approach relies on detecting and treating anemia before surgery, reducing blood loss during surgery, and optimizing management after surgery.
Forensic examiners can use blood or teeth samples to estimate an individual's age with great accuracy, helping track down criminals or identify human remains. Researchers at KU Leuven developed a test based on four age-associated DNA methylation markers, achieving margins of error of 3.75 years for blood and 4.86 years for teeth.
A new study of DCD liver transplantations found no significant correlation between donor age and organ survival. The results suggest that stringent donor and recipient selection can help expand the donor pool for life-saving liver transplantation, making aged DCD organs more viable.
A Kaiser Permanente study found that introducing electronic order entry and care-decision support in emergency departments led to a significant increase in the timely administration of clot-dissolving treatments for patients with acute ischemic stroke. The technology helped minimize errors while improving patient outcomes.
A new study led by King's College London found that preserving the natural structure of dietary fibre during food production can help slow blood sugar levels after a meal. This could lead to the development of 'diabetic-friendly' foods with slower energy release and prolonged fullness.
A new study found that a commonly used diabetes treatment provides protection against terminal blood loss. Researchers identified how the medication works at a cellular level to prevent shock and death from massive blood loss.
A study in the Journal of Stroke and Cerebrovascular Diseases explores the pros and cons of general anesthesia versus conscious sedation for stroke patients undergoing minimally invasive surgery. The authors conclude that an anesthesiologist or anesthesia care team should be present to provide sedation, regardless of the approach used.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that interrupting sedentary behavior with short walking breaks can improve children's blood sugar levels. This benefit was observed even after a sugary drink was consumed, suggesting potential long-term benefits for metabolic health.
The Wyss Institute has developed an improved blood-cleansing device that can treat sepsis by removing pathogens and toxins from the bloodstream. The new device uses a genetically engineered pathogen-capturing protein to bind all types of live and dead infectious microbes, including bacteria, fungi, viruses, and toxins.
Researchers have identified phytol and coumarin as key compounds responsible for repelling mosquitoes in traditional sweetgrass. The study, presented at the American Chemical Society meeting, demonstrates a scientific basis for the folklore of using sweetgrass to deter biting insects.
Researchers found that vitamin D supplements improved vitamin D levels and reduced falls in a five-month trial. The study suggests vitamin D may help maintain muscle integrity and strength, reducing the risk of falls in vulnerable populations.
Researchers have developed a new probe that can detect blood clots in any part of the body using positron emission tomography (PET). The probe, called FBP8, contains copper-64 and has shown promise in detecting blood clots in rats, paving the way for future human trials.
A team of international researchers led by Massachusetts General Hospital has identified the DCHS1 gene as the cause of the common form of mitral valve prolapse, a heart valve disorder that affects nearly 2.5 percent of the population. The study reveals that mutations in this gene lead to defects in the formation of the mitral valve.
A study published in JAMA Ophthalmology has found associations between lower blood manganese levels and higher blood mercury levels with a greater risk of glaucoma diagnosis. The research suggests that trace metals may play a role in the pathogenesis of glaucoma, and future investigations could explore potential neuroprotective effects.
A study published in JAMA Surgery found that women who underwent Roux-en-Y gastric bypass surgery had a faster increase in blood alcohol concentration and reported greater feelings of drunkenness. This alteration in alcohol metabolism increases the risk of developing alcohol use disorders, highlighting the need for public awareness.
Replacing time spent sitting with standing can lower blood sugar and cholesterol levels, according to a new study. Standing for two hours a day was associated with improved waist circumference and reduced risk of metabolic disorders.
A new blood test can predict the severity of traumatic brain injuries and identify patients who may benefit from extra therapy. The test measures brain-derived neurotrophic factor (BDNF) levels in the blood, which can help doctors advise patients on treatment and monitor their recovery.
Researchers at Johns Hopkins Medicine found that nearly half of hospital-acquired blood clots were not preventable despite proper use of preventive therapies. The study suggests that measuring prevention efforts, rather than just numbers of clots, is essential to accurately penalize hospitals.
Researchers at the University of Montreal successfully block apoC-III gene expression, demonstrating significant decreases in triglyceride levels. This breakthrough could lead to precise interventions for severe hypertriglyceridemia, reducing cardiovascular risks.
A new study has found that biomarkers, specifically phosphatidylethanol (PEth), are significantly higher in binge drinkers than moderate drinkers. PEth levels were positively correlated with the number of drinks consumed and self-assessment survey scores.
Researchers at Children's Hospital Los Angeles have shown improved outcomes in using stem cell transplantation to treat juvenile myelomonocytic leukemia (JMML), a rare form of chronic blood cancer. The study found that half of patients can be cured from their disease, and a potential standard conditioning regimen has been identified.
A recent study published in The Journal of Experimental Biology found that boa constrictors rapidly shut down the circulation of their victims. The snakes cut off the blood supply to vital organs, causing cardiac arrest and death within seconds. This discovery sheds new light on the mechanisms of snake constriction.
More adults are visiting doctors for anticoagulant treatment due to the popularity of new direct oral anticoagulants (DOACs), which have fewer food and drug interactions than warfarin. The study found that DOACs have risen to nearly match the use of warfarin, with 57% of anticoagulant visits related to warfarin use in 2014.
A 10-point questionnaire, known as the Alcohol Use Disorders Identification Test (AUDIT), is more effective than measuring blood alcohol level in detecting patients with at-risk drinking behaviors. The study found that up to 50% of trauma patients have alcohol in their bloodstream, and brief interventions can lead to a 50% reduction in...
Hereditary angioedema type III is caused by a mutated blood protein factor XII that leads to excessive bradykinin production and vessel leakage. Researchers have identified a natural inhibitor that can block the mutated protein, providing hope for a new treatment.
A large-scale study of over 30,000 men found no link between testosterone therapy and venous thromboembolism. The study suggests that testosterone therapy is not associated with an increased risk of blood clots in veins, which is a common cardiovascular illness.
Researchers found a new treatment approach for blood clots that allows patients to go home the same day, reducing hospital stays and costs. The treatment, rivaroxaban, also reduces recurrent thrombosis and bleeding rates.
A new drug, patiromer, significantly reduced serum potassium levels in patients with diabetic kidney disease and hyperkalemia. The study found that patiromer maintained normal potassium levels over 52 weeks, with minimal discontinuations due to adverse events.
Researchers at the University at Buffalo School of Public Health and Health Professions will examine diver physiology during and after underwater activities. The study aims to develop Navy diving protocols to prolong endurance and make missions safer for divers.
Patients with a first episode of pulmonary embolism who received 6 months of anticoagulant treatment showed reduced risk of additional blood clots and major bleeding when treated for an additional 18 months. However, this benefit was not sustained after discontinuation of therapy.
The American Heart Association/American Stroke Association recommends the use of brain stent retrievers in certain patients undergoing acute ischemic strokes. The devices can restore blood flow and reduce stroke damage when treated promptly, making them a valuable option for carefully selected patients.
The new consensus statement recommends drinking when thirsty to prevent hyponatremia, a potentially fatal condition caused by excessive fluid intake. The strategy aims to limit drinking in excess and develop hyponatremia while providing sufficient fluid to prevent dehydration.
A University of Kentucky researcher is developing an artificial blood technology for mosquitoes, which can help sustain colonies in resource-limited areas and combat diseases like malaria. The approach involves sterilizing mosquitoes using a bacterium and has already shown promising results in controlling Asian tiger mosquito populations.
A new study found that certain pollutants penetrate further into the feto-maternal system, causing harm to fetuses. The research analyzed pollutant levels in cord blood and maternal tissues, revealing heavy metals like mercury and lead easily pass through the placental barrier.