Articles tagged with Blood
Researchers at the University of Pittsburgh have developed a unique method to detect antibodies in the blood, enabling simple diagnostic tests for diseases without known microbial causes. This approach successfully led to the detection of HIV antibodies and holds potential for diagnosing various conditions with just a single drop of bl...
Systemic glucocorticoids increase risk of life-threatening staph infections by 2.5 times, with higher doses associated with greater risk
A clinical trial showed that stem cells from umbilical cord blood significantly reduced Eczema Area and Severity Index scores by 50% in high-dose patients. Immune-related markers of atopic dermatitis also decreased, with persistent improvement throughout the 12-week follow-up period.
Pediatric leukemia patients exposed to higher concentrations of methotrexate are more likely to struggle with mental flexibility, organization, and related skills as long-term survivors. Brain imaging revealed changes in brain regions associated with executive functioning, including increased activity in the frontal lobe region.
A wearable artificial kidney has been shown to effectively clear waste products from the blood while maintaining electrolyte balance. The device, still requiring redesign for technical issues, offers an alternative to conventional hemodialysis, providing greater patient satisfaction and mobility.
Researchers found that female atrial fibrillation patients are less likely than men to receive blood thinning therapies. The study used a computerized decision support tool to review medical therapies for over 1,500 patients and found significant sex differences in treatment.
Researchers found progranulin levels in cerebrospinal fluid differ from those in blood, challenging its use as a biomarker for neurodegenerative diseases. This discovery sheds new light on the biological processes underlying Alzheimer's and other common neurodegenerative diseases.
Researchers analyzed untreated acute stroke patients and found no correlation between salvageable penumbra and time. However, they discovered a significant association between salvaged penumbra and collateral blood flow rerouting of the blocked arteries.
A new study from Harvard T.H. Chan School of Public Health finds that exposure to common flame retardant chemicals may increase the risk of thyroid disease in women, particularly post-menopausal women. Women with higher levels of these chemicals in their blood are more likely to develop thyroid problems.
Researchers found that combining TXA delivery methods reduced blood loss by 37% compared to IV alone following TKR. The study showed no thromboembolic complications, with one patient requiring a postoperative blood transfusion.
Researchers at Penn Vet found that a common blood test may also indicate hypercoagulability in animals. A study of hundreds of dogs found that shortened prothrombin time and activated partial thromboplastin time were associated with clinical signs of hypercoagulability, including clots and suspected pulmonary thromboembolism.
Researchers at the University of Copenhagen have identified a new gene linked to familial hypercholesterolemia, a genetic disorder causing very high blood cholesterol. High levels of lipoprotein(a) in the blood increase heart attack risk by five times.
A computerized decision support tool helps physicians and patients make informed decisions about blood thinning treatment to prevent strokes in individuals with atrial fibrillation. The tool, which takes into account patient characteristics and medical therapies, resulted in a significant reduction in deviations from recommended treatm...
Researchers at the University of Cincinnati developed a simple in-home screening device to monitor blood-clotting levels, reducing frequent lab tests and costs. The paper-based test stick can quickly reveal changes in coagulation properties, allowing patients to detect potential issues early.
Researchers found that patients treated with as-needed blood thinners and regular pulse monitoring had lower stroke risk compared to those taking long-term anticoagulation medications. The study showed minimal bleeding incidents and no strokes or transient ischemic attacks among participants.
A new study of over 10,000 patients with atrial fibrillation (AF) and those without found that AF patients treated with warfarin had higher rates of dementia, Alzheimer's disease, and vascular dementia. The study suggests that the efficacy of therapy is strongly associated with dementia risk.
Researchers at WashU Medicine have developed a newborn screening test for Niemann-Pick type C, a progressive neurodegenerative disease that typically isn't diagnosed until age 2. The test quickly identifies infants with NPC using a two-tiered testing strategy and measures levels of bile acid produced by the liver.
A small study by University of Florida researchers suggests that as we age, we may become more sensitive to pain and experience a quicker and higher magnitude inflammation. This could predispose older adults to chronic pain, making anti-inflammatory medication an early treatment option.
A study published in JAMA Internal Medicine found that young adults who made small dietary changes and engaged in regular physical activity successfully prevented weight gain. The 'small-change' group lost an average of 1.2 pounds over two to three years, while the 'large-change' group lost nearly 5.2 pounds.
Researchers have identified a hybrid form of the common house mosquito in eastern Austria that can transmit exotic diseases such as West Nile virus. The hybrid mosquitoes can act as bridge vectors, picking up pathogens from their original host birds and potentially transmitting them to other birds or humans.
Patients treated with stent retrievers within 2.5 hours of symptom onset had a 91% chance of functional independence, compared to 81% for those treated between 2.5-3.5 hours. Inter-facility transfer times can significantly delay treatment.
Patients on warfarin have poor knowledge about diet and drug interactions, which can lead to fatal side effects. Experts recommend consistent monitoring and education to improve patient outcomes.
Researchers at the University of Tokyo developed an ultrathin, ultraflexible, protective layer that enables creation of electronic skin displays. The technology allows for wearable electronic devices to be attached to the body without damaging them.
Researchers have developed a potentially life-saving drug therapy called ALM that can reduce internal blood loss by up to 60% in traumatic injuries. The treatment, administered intravenously, has shown promise in treating shock and stabilizing vital organs.
A new generation of blood thinners can significantly reduce the risk of stroke in patients with atrial fibrillation without requiring frequent monitoring. However, careful consideration must be given to individual patient factors such as age and kidney function before prescribing these medications.
Researchers are testing blood samples from patients with myasthenia gravis to determine the presence of two new antibodies, agrin and LRP4. The study aims to characterize their clinical symptoms and develop treatment strategies for double-negative patients.
Researchers at Marshall University have found that blocking small cell lung cancer tumors' blood supply can delay their growth and regrowth after treatment. Synthetic molecules like MG624 show promise in delaying cancer relapse and improving patient outcomes.
A University of Virginia study found that false beliefs about biological differences between black and white people contribute to undertreated pain among black patients. White medical students and residents who held these false beliefs showed lower pain ratings and less accurate treatment recommendations for black patients.
Researchers have found a link between lead contamination in Flint's soil and elevated blood levels in local children, particularly in low-income areas. The study suggests that soil lead is an additional factor contributing to the city's ongoing water crisis.
A study found that marathon runners with 'salty' sweat had lower electrolyte levels in their blood despite proper hydration and nutrition. This suggests that sweat electrolyte concentration can impact physiological conditions during long-distance events.
A study by University of Pittsburgh Graduate School of Public Health suggests that middle-aged black women have higher levels of a protein in their blood associated with heart disease risk. The research recommends routine blood testing for this population to determine heart disease risk and potentially start therapies.
A new study published in JAMA Neurology detected evidence of concussions in patients up to 7 days after injury using a simple blood test. The discovery could greatly expand the window for diagnosing concussions, especially in children who experience delayed symptoms.
Higher concentrations of BPA in pregnant mothers' blood are associated with an increased risk of preterm birth. The study found that women with higher BPA levels were more likely to deliver their babies early compared to those with lower levels.
Researchers identified biological markers in blood samples from latently infected individuals that can predict the risk of developing active TB. These biomarkers may enable targeted therapies to prevent illness in high-risk individuals.
A new technique enables rapid and accurate measurement of bacteria levels in packaged food and medical samples without physical contact. The method uses tunable diode laser absorption spectroscopy and can provide real-time analysis, reducing the risk of food poisoning and improving blood quality.
A new study analyzing 50 years of hemophilia care data found significant disparities in outcomes between men with severe and mild forms of the disease. Men with severe hemophilia were more likely to experience physical limitations, disability, and frequent bleeding despite access to effective therapies. The study emphasizes the need fo...
Researchers found nearly half of AF patients at the highest stroke risk were not prescribed oral anticoagulants, highlighting a significant treatment gap. The study emphasizes the need to address barriers to anticoagulant prescription and optimize risks versus benefits for these high-risk patients.
Researchers have found a correlation between hypogonadism and high Gleason scores in prostate cancer patients. This association could help predict patient outcomes before surgery, allowing for more targeted treatment strategies.
New Cornell research reveals genetic cues from male mosquitoes affect female reproductive tract gene expression, influencing blood feeding, egg development, and immune defense. This study aims to develop novel strategies for controlling mosquito populations to fight diseases like Zika virus.
Researchers at the University of Granada have developed a non-invasive method to detect celiac disease in children aged 2-4. The test uses capillary blood and detects disease markers, allowing for early diagnosis without the need for blood extraction or intestinal biopsy.
Researchers discovered a mutated ANGPTL4 gene that lowers triglyceride values in the blood, reducing the risk of coronary disease. This breakthrough may lead to new medications that simulate the effect of this mutation, providing a concrete goal for future research.
Researchers identified 12 classes of drugs and 4 main mechanisms that can cause small arteries to constrict in response to cold, limiting blood supply. A recent study published in British Journal of Clinical Pharmacology highlights the need for further investigation into this condition.
Researchers found significant differences in blood clot structure between adults and neonates, which may pose an increased risk of thrombosis in newborns. The study suggests that using adult fibrinogen in neonatal patients may be detrimental to their health, highlighting the need for more effective treatment strategies.
Researchers linked high C-Reactive Protein levels to increased ischemic stroke risk, identifying gene variations that drive these risks. A new discovery may allow doctors to predict patients' risk of having a second stroke using a commonly performed blood test and their genetic profile.
Researchers found that TXA reduced the need for a blood transfusion by more than 50% in hip and knee replacement surgery. Topical versus intravenous administration of TXA showed similar effectiveness in reducing blood loss and transfusion rates.
The risk of catching Ebola from a survivor is very low, with most body fluids cleared within weeks apart from semen. Studies found that infected blood is the most infectious, but social contact poses little risk.
Researchers found that wealthier seniors in Ontario were prescribed a new blood thinner more often than poorer seniors, but access improved when the drug was covered by publicly funded plans. The study highlights socioeconomic barriers to accessing new medications and calls for timely reimbursement decisions by provinces.
A new medication called idarucizumab reverses the blood-thinning effects of dabigatran in patients with brain hemorrhage, allowing for quicker treatment and reducing complications. The study showed that idarucizumab effectively reversed dabigatran's anticoagulant effects in 90% of patients.
A phase-3 clinical trial has demonstrated the effectiveness of clot-busting therapy in reducing mortality and post-stroke disability in patients with severe intraventricular hemorrhage. The treatment significantly reduced death rates by 10% and improved functional recovery in patients with larger clots.
Researchers found that brain imaging can accurately predict patient outcomes and identify those who may benefit from clot removal up to 18 hours after symptom onset. This approach could improve treatment eligibility and outcomes for ischemic stroke patients.
Researchers found that people with migraines with aura are more likely to have strokes caused by blood clots in the heart or brain's blood vessels. Migraine with aura patients were 2.4 times more likely to have an ischemic stroke, and three times more likely to have a cardio-embolic stroke.
The 'NewSTEPs 360' program aims to improve timeliness measures in newborn screening, resulting in more infants receiving early treatment for rare but serious conditions. The initiative provides quality improvement training and technical assistance to selected states, aiming to reduce delays in diagnosis and save lives.
Researchers tested a peptide vaccine targeting Ang II in rats, finding high levels of anti-Ang II antibodies protected against stroke-induced brain damage. The vaccine also showed potential for long-term blood pressure reduction, offering a promising therapy for hypertension and stroke prevention.
A large nationwide study found that testosterone treatment improved sexual desire and function, as well as mood and depressive symptoms, in men with low testosterone levels. The treatment also showed no significant increase in cardiovascular issues.
Researchers found three genetic variants linked to increased blood clot risk in African Americans, affecting thrombomodulin expression. Approximately 36% of Africans carry these variants, doubling their risk for venous thromboembolism.
Researchers analyzed data from 10 Michigan hospitals to show significant variation in peripherally inserted central catheter (PICC) use, with nearly one in four PICCs removed within five days. The study also found wide variation in complication rates, including serious and life-threatening events such as blood clots and infections.
Researchers at Umea University have found that the protein FGF21 redistributes fatty acids through two mechanisms, leading to improved pharmaceutical treatment options for obesity-related diseases. The study also shows that FGF21 can activate the enzyme Lipoprotein lipase, increasing the hydrolytic cleavage and uptake of blood lipids.
A new study has identified four genes associated with leptin levels, providing insight into the complex relationship between body fat and hunger. The findings have important implications for understanding obesity and developing targeted treatments.
Researchers have deciphered the genome of the blacklegged tick, revealing secrets to its success as a disease vector. The study identifies genes and protein families that shed light on why ticks excel at spreading pathogens, providing potential targets for new interventions.
A recent study from Lund University found that barley can rapidly improve people's health by reducing blood sugar levels and risk for diabetes. The special mixture of dietary fibres in barley stimulates the increase of good bacteria and the release of important hormones.