Articles tagged with Blood
Researchers have uncovered the molecular mechanism that regulates how the heart pumps blood, with titin protein identified as key player. The study's findings could lead to new medications more effectively treating heart failure.
The Zika virus is primarily transmitted by Aedes mosquitoes, which also spread dengue and chikungunya viruses. Physicians should be aware of symptoms in travelers returning from affected regions and consider Guillain-Barré syndrome and microcephaly as potential complications.
Researchers at Tel Aviv University have developed a new blood test that can determine an individual's vulnerability to stress and PTSD. The test combines genetic testing with brain imaging to identify a specific alteration in the expression of microRNA miR-29c, which is linked to slow recovery from stress.
A new investigation by The BMJ questions the validity of a pivotal trial supporting rivaroxaban's approval, citing concerns over a faulty blood clotting test device. Doctors and scientists are now calling for an independent investigation and access to original trial data to clarify the drug's benefits and harms.
A follow-up study found most vaccinated children maintained anti-hepatitis A antibodies until age 15-16 years, suggesting protection for at least 30 years. The findings support current US vaccine recommendations and do not require booster doses.
A comprehensive review reveals frequent opportunities for HCV exposure in Ghana, including traditional practices like circumcision and home births. The study found a substantial genetic diversity of HCV-2, confirming its long epidemic history in the country.
A study of nearly 1 million Ontario adults found that preoperative laboratory tests were conducted prior to approximately 30% of low-risk surgical procedures. The rate of these tests varied significantly among institutions, with some performing them in over 98% of cases and others in none.
Researchers at Wake Forest Baptist Medical Center found an association between obesity and the formation of blood clots in children and adolescents. Obesity was a statistically significant predictor of blood clot formation in juveniles, contributing to increased incidence of pediatric venous thromboembolism.
A recent study from the University of Eastern Finland found that a common gene mutation in healthy children improves blood lipid profiles while raising liver values. The TM6SF2 gene mutation was associated with lower triglyceride and LDL cholesterol levels, as well as higher ALT values indicative of changes in liver metabolism.
A recent study published in Circulation found that cangrelor reduces the odds of major adverse cardiovascular events by 35 percent and stent thrombosis by 61 percent in women compared to standard therapy. The research provides important reassurance on the safety and efficacy of blood thinners in women.
Men with high urate levels have a lower risk of developing Parkinson's disease, according to a study published in Neurology. The study found that men with the highest urate levels were nearly 40% less likely to develop the disease.
The study reveals that the source of stem cells used for hematopoietic stem cell transplantation in patients with bone marrow failure varies worldwide. Bone marrow is predominantly used in the Americas and Europe, while cord blood and peripheral blood stem cells are more commonly used in other regions.
A new study found that a blood test monitoring dead cancer cell DNA is superior at tracking the severity and potential spread of metastatic melanoma. This non-invasive test detected cancer recurrence in 85% of patients, compared to 54% with the current standard test.
Researchers at Cedars-Sinai are working on a new risk assessment tool to identify patients susceptible to sudden cardiac arrest. The goal is to predict those at risk for the fatal heart rhythm malfunction, which claims 350,000 lives annually in the US.
A quick screening method has been used to identify and test promising anti-Ebola drugs. The method, which allows for the evaluation of candidate drugs and comparison of antiviral effectiveness, has shown potential in reducing the emergence of drug resistance and increasing confidence in experimental results.
Researchers have developed a blood test to predict the development of preeclampsia, enabling early diagnosis and prevention of complications. The test measures the ratio of serum sFlt-1 to PlGF proteins, allowing for reliable prediction within one week.
A $13.5 million funding award from the Patient-Centered Outcomes Research Institute (PCORI) will support a study analyzing the safety and effectiveness of three blood-thinning drugs used to prevent post-surgery blood clots in patients undergoing hip and knee replacement.
Researchers found that infusing a small amount of IL-17A can prevent or reverse diabetic nephropathy in animal models. The therapy also reduced high levels of fat in the blood and aided survival and regeneration of key kidney cells, including podocytes and epithelial cells.
Researchers have identified two genetic variants, ABCA7 and MA4A6A, associated with brain atrophy in Alzheimer's disease. The study found that protein levels in the blood produced by these genes could be used as biomarkers for diagnosis and potential treatment.
A study published in the Journal of the American Society of Hematology found that women on blood thinners can take hormone-containing contraception or hormone replacement therapy without an increased risk of blood clots or uterine bleeding. The study analyzed data from 1,888 women and showed similar incidence rates of blood clots and a...
A study found that people scoring well on the Life's Simple 7 checklist for a healthy heart have lower risk of developing heart failure. The measures include managing blood pressure, cholesterol, and sugar levels, as well as getting physically active, eating better, losing weight, and quitting smoking.
A new study by Cedars-Sinai Medical Center found that more than half of patients who experience sudden cardiac arrest ignore key symptoms prior to the event. These symptoms often include chest pain, shortness of breath, and palpitations, occurring up to a month before the fatal heart rhythm malfunction.
Researchers found that maintaining potassium levels low in an insect's blood is crucial for survival during cold exposure. The study, published in Scientific Reports, suggests that the Malpighian tubules play a key role in regulating salt balance in insects.
A 14-year study found that annual screening with a blood test utilizing the Risk of Ovarian Cancer Algorithm (ROCA) significantly reduced mortality from ovarian cancer, particularly in women without evidence of cancer at study entry. The results showed a 20% reduction in risk of dying from ovarian cancer.
Researchers at New York University found that individuals with autism have unstable blood vessels, disrupting brain function and circulation. The study identified a correlation between angiogenesis and neurogenesis, potentially leading to novel therapeutic interventions.
A small study found that watching horror movies significantly increased blood coagulant factor VIII levels in young and healthy adults, suggesting a physiological response to fear. The researchers argue that this increase is an evolutionary adaptation to prepare the body for blood loss during life-threatening situations.
A study from the University of Pennsylvania found that the CAP2 gene is responsible for cardiac conduction disease in mice, leading to sudden cardiac death. The researchers also discovered that the gene's absence affects the heart's ability to contract and regulate blood flow.
Researchers have found novel mechanisms to inhibit chikungunya virus at multiple stages of infection, including entry and release from cells. The discovery could lead to the development of a single vaccine that protects against multiple alphaviruses.
A Johns Hopkins study suggests that individualized report cards improve VTE prevention efforts, increasing correct therapy use and resident performance. The approach also boosted trainee morale, with a significant spike in resident satisfaction scores.
A large US study found that over half of patients with controlled type 2 diabetes receive more tests than recommended guidelines, leading to overtreatment and potential patient harm. The study also highlights fragmented care coordination as a possible reason for repeat tests.
Researchers at UC San Diego are investigating DNA methylation in the blood as a potential signature for Parkinson's disease. The study, funded by the Michael J. Fox Foundation, aims to improve early diagnosis and treatment of the chronic movement disorder.
A new study has found that combining the blood thinner warfarin with certain diabetes medications increases hospitalizations for falls, altered mental state, and insulin shock among Medicare patients. The study's findings have significant implications for patient safety and healthcare costs.
A systematic review of 440 participants found that nail varnish affects oxygen saturation measurements by up to 2%, but this is within error margins and not significant in clinical practice. Modern devices with high-performance LED technology can accurately measure oxygen saturation despite nail varnish.
Researchers have discovered a blood test for the SNTF protein, which may predict long-term cognitive impairments in concussion patients. The study suggests that even mild concussions can cause permanent damage to brain wiring, leading to cognitive impairment.
Research led by Johns Hopkins Bloomberg School of Public Health finds that blood from preschoolers contains molecular evidence of prenatal smoking exposure, detectable 5 years post-birth. The study uses epigenetic analysis to identify a signature associated with smoking during pregnancy, which may also be linked to other toxins and hea...
Researchers at UC Santa Barbara have developed an insulin pill using novel drug delivery technology that shows early promise as a form of diabetes therapy. The pill's oral delivery system could circumvent the discomfort associated with injections, leading to improved patient compliance and potentially more effective treatment.
A large-scale study of newly arrived refugee children in the US has identified key public health concerns, including hepatitis B, tuberculosis, and parasitic worms. The study suggests that existing medical screening guidelines remain relevant but recommends further analysis and resource allocation for refugee populations.
Researchers at McMaster University have developed an antidote that reverses the effects of two new blood thinners, apixaban and rivaroxaban, within minutes. This breakthrough may help save lives by quickly reversing bleeding complications in emergency situations.
Researchers developed a new therapy by pairing snake venom with nanofibers to promote localized blood clotting at wound sites. The therapy, tested on rats treated with heparin, shows promise for making surgery safer for human patients on blood thinners.
Researchers found that individuals with better blood sugar control after consuming barley kernel bread had a different balance of gut microbes. The study suggests the importance of individualized dietary guidelines based on gut microbiota. Further studies are planned to confirm the findings and develop combination products with Prevote...
Scientists found that asymptomatic people can infect mosquitoes with dengue virus, representing three-quarters of all dengue infections. This challenges existing theories and highlights the potential for these individuals to contribute to the spread of the virus.
A new study found that short bursts of high-intensity exercise improved cholesterol, blood sugar, and weight among Type 2 diabetes patients. Researchers compared the effects of 30 minutes of lower-intensity exercise to three months of high-intensity exercise in 10-minute bursts, finding a significant difference in outcomes.
Researchers are developing a simple, inexpensive blood test that can detect the risk of Alzheimer's disease in individuals with Down syndrome. The test aims to identify people who will develop the disease before cognitive symptoms appear.
A new blood test has been developed to detect foetal blood group, sex, and genetic conditions in unborn babies with high accuracy. The test is non-invasive and costs a fraction of traditional amniocentesis tests.
The FIGHT study found that liraglutide, a type-2 diabetes drug, did not improve the clinical stability or pumping action of the heart in patients with advanced heart failure. Researchers discovered no significant favorable effects of liraglutide on heart function or quality of life among participants.
A lack of sufficient sleep reduces the body's sensitivity to insulin, impairing blood sugar regulation and increasing diabetes risk. The study found that insufficient sleep impairs insulin sensitivity, leading to a reduced ability to regulate blood sugar levels.
Italian scientists discover higher blood levels of zonulin in patients with non-coeliac gluten sensitivity (NCGS) and irritable bowel syndrome (IBS), suggesting a role for the protein in developing these conditions. The findings may lead to new treatment strategies for NCGS and IBS.
A pharmacy-led glycemic control program is linked to improved outcomes for surgical patients with diabetes, including fewer complications and readmissions. Patients in the program had better blood sugar control, reduced hospital readmissions, and lower medical costs.
Researchers found that fitter men performed better mentally than less fit men by using parts of their brains in the same way as in their youth. Aerobic fitness was associated with higher left-PFC activity and faster reaction times, indicating older adults who use a more youth-like brain perform better.
Researchers at the University of South Carolina have developed a new technique called 'steam thermography' that can detect blood spots in crime scenes more effectively than luminol. The method uses thermal imaging and a hand steamer to highlight where blood is present, even in highly diluted samples.
A large registry study of almost 50,000 patients in Sweden found that transfusion with stored blood does not influence patient outcomes after heart surgery. The study provides firm reassurance that current blood storage practices are safe.
Researchers at UCSB have discovered a mechanism by which secreted proteins age and turn over, shedding light on a crucial aspect of health and disease. The discovery identifies over 600 proteins with molecular signs of aging and turnover, including regulators of proteolysis, blood coagulation, and immunity.
A team of researchers at the University of Virginia Health System is exploring the link between glucose metabolism and heart function. They aim to identify a therapeutic window where intervention can prevent cardiac dysfunction and subsequent heart failure.
Scripps Health cardiology experts will share leading-edge techniques for improving heart care during the annual Transcatheter Cardiovascular Therapeutics (TCT) symposium. Matthew Price, M.D., will present on the WATCHMAN left atrial appendage closure device, an alternative to blood thinners for stroke prevention.
Researchers found that people with a common genetic variant in MTNR1B may be more at risk for developing type 2 diabetes when taking melatonin close to mealtimes. The study suggests that genetics can impact blood sugar control, highlighting the need for caution when taking melatonin near meal times.
A new study from the Cedars-Sinai Heart Institute shows that about 15% of patients with bioprosthetic aortic heart valves develop blood clots on the leaflets, which can impair valve motion. However, anti-coagulation medications like Warfarin quickly resolve the issue for all patients, regardless of the type of valve or procedure.
Researchers at the University of British Columbia have created a self-propelled powder that can deliver coagulants against severe blood flow to treat trauma-related bleeding. The innovative particles use gas-generating calcium carbonate micro-particles to propel clotting agents deep into damaged tissue.
Researchers found that sedentary time was associated with higher risks of heart and diabetes problems, regardless of exercise levels. The study suggests that reducing sedentary time can be beneficial for Hispanic adults' overall health.
A new treatment involving the removal of a protein called sFlt-1 from the blood has shown promise in prolonging pregnancy in women with preeclampsia. Pregnancy continued for an average of 8 days and 15 days in treated women, compared to just 3 days in untreated women.
Researchers at the University of Montreal developed rapid and inexpensive medical diagnostic tests using DNA molecules. The new technology detects protein markers linked to various diseases and can be used to build point-of-care devices for quick medical diagnosis, potentially impacting global health.