A computer model of tuberculosis has shown that daily antibiotic regimens are more effective than once or twice a week in preventing drug-resistant strains. The study suggests that increasing the number of doses and improving drug properties can lead to significant improvements in treatment success rates.
A new vibration-based prevention technology has been shown to reduce apneic events and improve critical clinical parameters in prematurely born infants. The technology, tested in a neonatal intensive care unit, demonstrated a 50% reduction in apnea incidence and ameliorated oxygen desaturation events.
The study reveals that Yakutian horses developed their adaptations in less than 800 years, making it one of the fastest examples of adaptation in mammals. The genome analysis shows that the founders of modern Yakutian horses entered the region with Yakut horse-riders in the 13-15th century AD.
A recent study published in Infection Control & Hospital Epidemiology found that patients struggle to understand CMS hospital infection data, which is meant to help them make informed decisions. The authors recommend improving the way this data is presented to increase transparency and quality of care.
Researchers at the University of Geneva discovered that Hydra cells can modify their genetic program by overexpressing genes involved in nervous functions. This study sheds light on cellular plasticity, a phenomenon that could influence research into regenerative medicine and neurodegenerative diseases.
The Rochester Institute of Technology and Raytheon Vision Systems collaboration has received $2 million in NSF funding to develop new infrared detectors grown on silicon wafers. The technology is expected to increase discovery space for telescopes and expand its use to homeland security, remote sensing, and biomedical imaging.
Researchers found that older toddlers as young as 32 months prefer looking at average-weight figures over obese ones, with maternal anti-fat prejudice strongly correlated. This suggests that children absorb and display societal attitudes early on, highlighting the need to address weight-based prejudice.
A new study from the University of Maryland School of Public Health found that children exposed to Medicaid in early childhood have significant improvements in adult health. The research suggests that increased access to and use of healthcare services, as well as reduced family medical debt, contribute to better adult outcomes.
A new study provides a quantitative estimate of the effects of continental flood basalts on climate, vegetation, and oceans during the time of the dinosaurs. The researchers found that temperatures would cool by as much as 4.5 degrees Celsius due to volcanic gas emissions but return to normal within 50 years after an eruption ceased.
Researchers at EMPA have developed tandem solar cells that convert a larger portion of light energy into electricity, using polycrystalline thin films and semi-transparent perovskite film. The new process enables large area low-cost processing and flexible plastic or metal foils as substrates.
A NASA study found that exposure to microgravity inhibits the ability of mouse embryonic stem cells (mESCs) to differentiate and generate most cell lineages. This inhibition has significant implications for human tissue engineering and the use of stem cells to regenerate adult tissues.
Researchers found CTCs in 100% of patients with suspected tumors, but only 4% detected through peripheral blood. Portal vein samples provided more accurate tumor cell information, enabling better clinical decisions. The test could help predict patient outcomes and guide treatment options.
A QUT research found that sharing economy model could be developed to support people experiencing financial hardship by providing essential services like food relief. Clients who interacted with each other at the centre appreciated social value and gained useful knowledge, while stigma attached to seeking help was reduced.
Researchers discovered that army ant bridges can move to span large gaps and change position as needed, balancing a cost-benefit trade-off between colony benefits and worker sequestration. This finding has implications for developing swarm robotics for disaster relief and exploration.
Koutschan, Kauers, and Zeilberger's paper proved the remaining conjectured formula for plane partitions, a significant experimental contribution. The work has connections to statistical mechanics, representation theory, and combinatorics, showcasing the prize-winning paper's impact on mathematics.
Cancer occurs when cell signals are dysregulated, leading to abnormal growth. The RET protein plays a crucial role in kidney and nerve development, as well as many human cancers.
Tropical Storm Annabelle formed on Nov. 21 with NASA's Terra satellite capturing its development, intensified winds reaching up to 67 mph/108 kph. The storm weakened on Nov. 23 as cloud tops warmed, indicating a decrease in convection and tropospheric height.
Researchers discovered that IR25a plays a key role in entraining fruit fly brains to small changes in temperature. The study found that when temperature fluctuations were large, flies lacking IR25a could adapt, but when they were small, the flies struggled to synchronize their circadian clocks.
Researchers found that tardigrades have a massive amount of foreign DNA, with around 17.5% coming from non-tardigrade sources, primarily bacteria. This challenges conventional views on how DNA is inherited and raises new questions about the connection between foreign DNA and extreme environment survival.
Researchers at the University of Notre Dame have discovered a compound that accelerates diabetic wound healing, opening doors to new treatment options. The study found that combining an MMP-9 inhibitor with enzyme MMP-8 enhances healing even further.
A new review of 45 years of medical literature found relatively few cases of meperidine-associated seizures, with coexisting conditions often contributing to the increased risk. The study concludes that meperidine's role as an effective anti-shivering agent should continue to be explored.
The BK polyomavirus often causes complications after kidney transplantation due to immunosuppressive drugs like Tacrolimus. Researchers have found that Tacrolimus directly activates virus replication, while Sirolimus inhibits it, providing a rationale for clinical trials.
A recent study found that oily waste containing natural radionuclides can strongly alter the microbial community in soil, selecting for resistant species and affecting community function. The long-term effects of such contamination on soil health and function are still unclear.
A new process removes contaminants from oil sands wastewater using sunlight and nanoparticles, offering a more effective and inexpensive alternative to conventional treatment methods. The technology breaks down persistent pollutants into individual atoms, completely removing them from the water.
Researchers measured thermal expansion of ceramics and silicon in a precise temperature range, revealing significant deviations from reference values. The results are crucial for future space missions like JWST and SPICA.
A study published in the journal Brain found that amyloid plaques around blood vessels in the brain can disrupt astrocyte function, leading to reduced cerebral blood flow. This could account for symptoms such as memory lapses, impaired decision-making, and personality changes associated with Alzheimer's disease.
The EORTC trial 26101 found that bevacizumab treatment in progressive glioblastoma patients did not confer a survival advantage despite prolonged progression-free survival. The combination of bevacizumab and lomustine may prolong PFS but does not impact overall survival.
Scholz has made significant contributions to seismology, bridging laboratory studies of rock mechanics with fundamental research on crustal-scale deformation. He has developed influential models for earthquake prediction and helped create regional seismic hazard maps.
Researchers have found that infertile animals appear to be protected from neurodegeneration in a study using C. elegans worms. The study, which appears online now, showed that infected worms display hallmarks of neurodegeneration similar to those seen in humans, but infertile animals resist this process.
Researchers at Case Western Reserve University have developed a stem cell treatment that mediates an immune response to spinal cord injury, reducing tissue damage and preserving function. The treatment, involving multipotent adult progenitor cells (MAPCs), was effective in preventing the cascade of immune responses that often lead to l...
A CU research study found that Latino patients on dialysis prefer aggressive care and earlier discussions about end-of-life decisions. The study highlights the importance of delivering palliative care in a culturally sensitive way to meet the needs of this growing segment of the US population.
A recent study published in Annals of Internal Medicine found that breastfeeding significantly lowers the risk of developing type 2 diabetes after gestational diabetes. Women who exclusively or mostly breastfed for at least two months after giving birth were half as likely to develop type 2 diabetes within two years after delivery.
Researchers at Stanford University School of Medicine discovered that genetic material from ancient viral infections is critical to human development. Blocking the production of a specific RNA molecule stops development in its tracks, they found.
In Gipuzkoa province, bird poaching continues to pose a threat to biodiversity conservation, with dozens of birds arriving at rehabilitation centers with firearm-inflicted wounds. Researchers analyzed data from 2006 to 2013 and found that the spatial distribution of shot birds was concentrated around fixed hunting stands.
A study found that young women who survived heart attacks or strokes had higher mortality rates from cardiovascular events, with an increased risk of cardiac and cerebral events. The researchers followed up with 226 women who had a heart attack, 160 women who had ischemic stroke, and 782 comparison patients for nearly 19 years.
Scientists warn that seismic surveys may cause behavioural changes and physical harm to turtles, including auditory damage and entanglement in gear. Researchers call for more research to address knowledge gaps and propose preventative measures to minimize the impact of seismic surveys on marine turtle populations.
Research led by Johns Hopkins Bloomberg School of Public Health finds that blood from preschoolers contains molecular evidence of prenatal smoking exposure, detectable 5 years post-birth. The study uses epigenetic analysis to identify a signature associated with smoking during pregnancy, which may also be linked to other toxins and hea...
A randomized controlled trial found that vitamin D supplementation did not reduce the number or severity of colds in adults with mild-to-moderate asthma. Achieving normal levels of vitamin D made no difference in cold frequency or severity, contradicting previous findings.
A new RAND Corporation study highlights the urgent need to improve short-term and long-term approaches to education for Syrian refugee children. The report recommends increasing instructional time, teacher training, and expanding school monitoring to address the crisis. Meanwhile, host countries face significant challenges in integrati...
A new study suggests that adding seaweed to processed foods such as frozen pizzas and hot dogs can reduce cardiovascular disease risk. Seaweed is rich in beneficial compounds like potassium salts, umami flavor, and dietary fiber, which may help regulate blood pressure and satiety.
Researchers used supercomputing to simulate protein motion over a huge range of timescales, revealing self-similar dynamics and out-of-equilibrium phenomenon. This breakthrough has significant implications for advancing energy and medical sciences.
Research suggests that wild pumpkin and squash were initially used for non-food purposes, such as containers and tools, before humans discovered their edible value. The loss of megafauna allowed wild plants to grow in new environments, leading to the evolution of palatability.
A new CHOP study finds that teaching problem-solving skills and leadership opportunities to elementary school-aged African-American girls can lower relational aggression. The Friend to Friend program improved social problem-solving knowledge and decreased relational aggression in urban minority girls, with positive effects lasting at l...
A computer simulation model projected that universal HCV testing and treatment in prisons could reduce HCV transmission in the general community, prevent liver-related deaths and cancer, and become highly cost-effective over 30 years. This would benefit not only the prison population but also society as a whole.
A study published in ZooKeys reveals patterns of chromosome numbers in antlion lacewings and an owlfly, indicating a possible common ancestor. The researchers found that some antlion species have higher chromosome numbers than expected, which may be ancestral traits.
The American College of Physicians recommends prescribing generic medications when available, as it improves health outcomes, reduces harm, and eliminates wasteful practices. Generic substitution can lead to better long-term medication adherence and save patients $1.4 billion annually.
A team of researchers used a non-invasive method to extract protein from medieval parchment samples, identifying the use of multiple mammal species in some manuscripts. The study resolves a long-standing controversy over the origin of 'uterine vellum' and sheds new light on medieval manuscript production techniques.
A new RAND Corporation study found that hiding tobacco products at convenience stores significantly reduces teenagers' susceptibility to future cigarette use. Researchers created a power wall with hundreds of tobacco products and had teens visit a replica store to shop while the product visibility was in one of three random locations.
Researchers at Duke University have created a technique for monitoring neurons in action with a time resolution of about 0.2 milliseconds, allowing for the first holistic view of neural activity in mammalian brains. This breakthrough enables scientists to study how brain activity translates into specific thoughts and behaviors.
A new study from the University of Maryland School of Public Health examined why African American and Hispanic women have higher rates of unintended pregnancies than White women. Researchers found that unique factors such as maternal age, income, health insurance status, US born status, and educational level contributed to these dispar...
Scientists have observed unusual seismic wave speeds that suggest the frozen olivine structure within the flat-slab slab has vanished and been replaced by a new unexpected structure. This implies that slabs are weak enough to deform internally in the upper mantle over time.
A new mattress device has been shown to reduce apneic events by 50% and improve breathing stability in preterm infants, with potential benefits for hospital stays and long-term cognitive development.
A recent study by the University of Chicago has found that loneliness triggers fight-or-flight stress signaling, leading to increased production of white blood cells and impaired antiviral responses. This shift in monocyte output contributes to loneliness' associated health risks, including premature death.
Researchers at Stanford University School of Medicine have identified a new class of RNA molecules that act as powerful tumor suppressors by inhibiting the cancer-causing protein KRAS. The study found that these RNAs, called SNORD50A/B, are deleted in over a quarter of common human cancers, leading to poorer survival rates for patients.
A new study published in the Journal of AAPOS found that children with amblyopia read more slowly than those with normal vision or strabismus. Amblyopic children exhibited about 35% more forward eye movements during reading, contributing to their slower reading speed.
A new study from the University of Nebraska-Lincoln found that children taking ADHD medications experience significant sleep problems, including delayed sleep onset and poor quality sleep. The researchers recommend frequent monitoring by pediatricians and consideration of behavioral treatments to minimize these adverse effects.
Typhoon In-fa has become elongated to the northeast with powerful thunderstorms surrounding its cloud-filled eye. The storm is expected to weaken over the next couple of days and approach the island of Iwo To, Japan on Nov. 26.
Researchers at the University of Florida have developed genetically modified citrus trees that exhibit enhanced resistance to greening, reducing disease severity and even remaining disease-free after 36 months. The study, published in PLOS ONE, used a gene isolated from Arabidopsis to create the new trees.
Late-treatment HIV patients with low CD4 levels progress to AIDS at high rates if immune response isn't recovered. However, if viral load is undetectable and CD4 counts rise above 200, mortality and progression decrease.
A report by the General Medical Council reveals that medics from different backgrounds perform better or worse due to multiple factors influencing their performance. The review highlights the importance of addressing differential attainment to create a level playing field for all candidates.