A study published in JAMA Network found that combining folic acid with the hypertension medication enalapril significantly reduced the risk of first stroke among over 20,000 Chinese adults with high blood pressure. The treatment also showed significant reductions in ischemic stroke and composite cardiovascular events.
Self-expanding TAVR shows continued survival advantage over standard surgery in high-risk patients with severe aortic stenosis. At two years, TAVR had 4.8% more survivors than surgery, and lower rates of strokes and major cardiovascular events.
A novel anti-clotting therapy was compared to established anticoagulants in a Phase III trial, but showed similar efficacy and higher moderate to severe bleeding rates, leading to its early termination due to allergic reactions.
Patients taking evolocumab, a new class of cholesterol-lowering medications, were half as likely to die or experience a heart attack/stroke compared to those on standard care. The study found that patients treated with evolocumab had significantly lower rates of cardiovascular events and adverse effects.
The study found that transcatheter mitral valve repair was successful for 91.8% of patients and reduced mitral regurgitation to mild or less in 63.7%. Institutional experience had a bearing on procedural success but not major adverse outcomes.
A study by University of Exeter researchers found that artificial light at night inhibits flowering in certain plants and suppresses aphid populations. The low-intensity amber light was more detrimental to the pea aphid population than white light, highlighting complex interactions between predators and resources.
Researchers found daily rhythms in metabolism among microbial communities in different ocean habitats, with common photoautotrophs initiating a cascade effect. This work suggests that microbial communities behave similarly across entire ocean basins.
The study found that adding ticagrelor to aspirin therapy after a heart attack significantly reduced the rate of subsequent death from cardiovascular causes, with benefits appearing for nearly three years. The trial recruited 21,162 patients and showed a 15% reduction in cardiovascular death with both ticagrelor doses.
Two new studies present striking findings on depression's influence on cardiovascular health, with depressed patients facing nearly double the risk of dying from heart disease. Additionally, survivors of heart attacks are found to be at higher risk for certain cancers, including lung and bladder cancer.
A recent study reveals a significant association between hair disorders and susceptibility to dental caries. The research found that polymorphisms in hair keratins are associated with increased risk of dental defects and caries, highlighting the importance of keratin components in tooth enamel structure.
A study comparing CT angiography and functional stress tests found similar clinical outcomes and minimal cost differences over three years. The tests had the same rate of death, heart attacks, and hospitalizations, despite initial cost savings from CT angiography.
Researchers create detailed digital terrain models of Hawaiian lava flows using a kite-mounted camera and GPS system. The models reveal complex patterns of lava movement and challenge current interpretations of Martian surface features.
A large trial found that patients with symptoms of heart disease have similar outcomes regardless of whether they undergo a functional stress test or a computed tomographic scan. However, the scan may be better at ruling out the need for subsequent tests and procedures in patients who are free of heart disease.
Studies link energy drink consumption to increased resting blood pressure, while smoking is associated with a higher risk of fractured stents in limb arteries. Social habits also play a role in recovery from early-onset heart attacks in low-income urban communities.
A research team at the University of Arizona has discovered sulfide chondrules in meteorites, providing evidence for a new type of environment in the early solar system. The discovery sheds light on the formation of elements essential for life, such as carbon and oxygen.
A study by Mayo Clinic researchers found that energy drinks increase resting blood pressure, particularly in caffeine-naive individuals, doubling their blood pressure compared to a placebo.
A study published in Patient Education and Counseling journal found that the title and font of participant information sheets can significantly influence pregnant women's perceptions of written information. Pregnant women perceived a program as less complex and easier to understand when presented with an easy-to-read font, while traine...
Engineers from Penn and ExxonMobil have uncovered the molecular mechanisms behind a common anti-wear additive used in motor oil. The study reveals that the additive forms a 'tribofilm' through stress-activated growth, providing a cushion effect against wear and tear.
Tropical Cyclone Nathan is moving east and will track over warm water, leading to intensification in the next two days. The cyclone has slowed down and continued hugging the eastern coast of Queensland's Cape York Peninsula.
Columbia engineers invent nanoscale IC that enables simultaneous transmission and reception at the same frequency in a wireless radio, doubling data capacity. The technology, known as full-duplex radio integrated circuits (ICs), cancels transmitter echo and enables conversations to take half the amount of time.
New research from Rice University reveals that nearly 70 percent of evangelical Christians do not view the intersection of science and religion as being in conflict. A recent study found that only 21 percent of evangelicals see science and religion as entirely independent, while nearly half view them as complementary. The study's findi...
Researchers have discovered a mechanism linking inhaled diesel pollution to respiratory distress by activating airway sensory nerves. The study found that diesel particles activate the TRPA1 channel, leading to increased oxidative stress and exacerbating respiratory conditions such as asthma.
The new quality measures aim to improve detection and treatment of childhood obstructive sleep apnea (OSA) by tracking the quality of services provided by clinicians. The measures, endorsed by the American Association of Sleep Medicine, focus on five desirable processes for pediatric patients with suspected OSA.
Acute kidney injury affects 13 million people annually and contributes to 1.7 million deaths. Experts believe it can be nearly eliminated in 10 years with current treatments costing $150 per patient. The Lancet Commission proposes a three-pronged strategy to raise awareness, improve diagnosis, and invest in sustainable infrastructure.
Researchers found significant increases in blood pressure during nighttime hours among participants exposed to prolonged periods of shortened sleep. The study, conducted at Mayo Clinic, used a controlled protocol to mimic the effects of sleep loss on the body.
The MMS mission will provide the first three-dimensional views of reconnection occurring in Earth's magnetosphere, releasing bursts of energy that can reach billions of megatons of TNT. Scientists expect the mission to help them better understand magnetic reconnection and its impact on modern technological systems.
A new flu vaccine that includes four strains of inactivated influenza has been found to be more protective than a similar vaccine containing only three strains. The addition of the fourth strain increases the chance the vaccine will match the circulating flu B strains without compromising protection against other strains.
The NCCN Clinical Practice Guidelines in Oncology provide evidence-based recommendations for smoking cessation in patients with cancer. Combining pharmacologic therapy and counseling is the most effective approach, leading to improved cancer treatment effectiveness and decreased recurrence.
A study found that guanabenz, a blood pressure medication, enhances an innate cellular protective response and prevents myelin loss in animal models of multiple sclerosis. The drug's unique mechanism provides protection against MS by reducing inflammation and preserving myelin levels.
The American Academy of Sleep Medicine published new quality measures for five common sleep disorders, promoting high-quality, patient-centered care. The measures aim to aid in evaluating the quality of care for conditions like restless legs syndrome, insomnia, and obstructive sleep apnea.
The FASEB MARC Program conferred $1,850 to 1 student and postdoctoral awardee from underrepresented groups, aiming to increase their engagement in biomedical research. The program seeks to promote diversity and inclusion in the scientific community.
An interdisciplinary team has developed a new method to analyze the structure of long bones, providing insights into human evolution and functional morphology. The study focused on the big toe's impact on gait and locomotion, revealing structural differences between humans, chimpanzees, and gorillas.
Researchers at the University of Copenhagen have made a groundbreaking discovery by bonding positively charged phosphorus atoms with positively charged hydrogen ones. This finding may revolutionize our understanding of how biologically important molecules like DNA and proteins form properly.
The FASEB MARC Program awarded Crystal Rogers from the California Institute of Technology $1,000 to attend the West Coast SDB Regional Meeting. The program aims to increase diversity in biomedical research by supporting underrepresented groups.
Tropical Cyclone Olwyn made landfall near Cape Cuvier in Western Australia, with NASA's Terra satellite capturing an image of the storm shortly after landfall. The cyclone was located about 43.5 miles southeast of Denham, moving south-southeast at 16 mph.
A cross-sectional analysis of 3,255 US non-smokers found a significant association between environmental tobacco smoke exposure and an increased risk of moderate/severe periodontitis. Serum cotinine levels were used to classify participants as exposed to ETS, with results showing a higher odds ratio among exposed individuals.
Researchers found that Nodal protein promotes melanoma cell growth and survival, leading to improved treatment outcomes with anti-Nodal antibody combinations. The study provides hope for patients with metastatic melanoma, a disease with limited treatment options.
A new study reveals that invasive species like Asian carp use landmarking to find mates by congregating at easily identifiable locations. This strategy allows them to reproduce even when population densities are low, posing a significant threat to conservation efforts.
Researchers studied a simple three-cell network within the roundworm brain and found that the collective state of the neurons determines the likelihood of movement towards an odor. The study suggests that nervous systems have internal patterns of activity that are as important as external signals in generating behaviors.
A recent study found that female mice are more attracted to the odor of healthy males than unhealthy males. However, they also choose to mate with unhealthy males, defying expectations and suggesting alternative factors at play in their mating behavior.
A cross-sectional study of 1,309 children found a significant association between low birth weight and the development of enamel defects. The study suggests that prenatal hypertension and prematurity may also contribute to the severity of these defects.
New research highlights poor connectivity of protected area networks in Southeast Asia, preventing lowland species from responding to climate change. Many low-lying PAs are isolated and not well connected to cooler forested areas at higher elevation.
NASA's Aqua satellite captures image of Tropical Storm Bavi showing strong thunderstorms and a thick band of storms north of the center. The Joint Typhoon Warning Center forecasts strengthening to hurricane-force on March 16 after passing over Guam.
A genetically engineered immunotoxin called DT2219 has shown safety and clinical effectiveness in a phase I trial for patients with relapsed/refractory B-cell malignancies. Two patients achieved durable objective responses, highlighting the potential of this new treatment approach.
Researchers report significant recovery after a single dose of an experimental treatment targeting interleukin-23, a key immune signaling protein in psoriasis. The study found nearly all patients experienced dramatic improvement in their symptoms, with an average 80% reduction in skin lesions.
Scientists have created global-scale maps of Mercury's surface chemistry, revealing previously unrecognized geochemical terranes with distinct compositions. The presence of these terranes has important implications for the planet's history and evolution.
A new study reveals that at least 2.3 million people may have died prematurely from kidney failure in 2010 due to lack of access to life-saving treatment. The researchers predict that the number of patients needing dialysis or transplantation will more than double to 5.4 million by 2030.
François Légaré, an INRS researcher, has been awarded the 2015 Herzberg Medal for his work in ultrafast molecular imaging. His research team made significant breakthroughs in dynamic imaging, capturing images of molecular reactions at unprecedented resolution.
A Kaiser Permanente study found that expanding blood pressure screenings to non-primary care settings can help identify more patients with high blood pressure and improve management. The study reported that patients identified with hypertension in non-primary care settings were more likely to be older, male, and non-Hispanic white.
The European technical report presents aquatic effect-based monitoring tools to address chemical pollution in surface waters, including bioassays and biomarkers for detecting toxic effects. These tools support the Water Framework Directive's goal of achieving a 'good status' for all Europe's surface waters by 2015.
Tropical Cyclone Pam is a powerful storm in the Southern Pacific Ocean, with hurricane-force winds affecting several provinces in Vanuatu. The storm's eye was captured by NASA's Aqua satellite, showing a 15 nautical mile wide eye just east of Vanuatu.
Scientists identified Blue13 genotype for the first time in Spain, indicating more aggressive and resistant strains of Phytophthora infestans. The detection has significant implications for potato producers, who must adapt to evolving disease patterns and develop new blight-resistant varieties.
Researchers at the Max Planck Florida Institute for Neuroscience will investigate a newly discovered circuit in the visual cortex using novel imaging technologies. The project aims to understand how this circuit processes visual information and interacts with other neural circuits.
Researchers have found that the length of Klf4 mRNA affects iPS cell reprogramming, with shorter forms leading to incomplete reprogramming. Longer forms result in more complete reprogramming and higher protein expression levels.
Researchers from General Atomics and Princeton Plasma Physics Laboratory made a major breakthrough in controlling heat bursts in fusion reactors. They found that tiny magnetic fields can create two distinct responses, allowing more heat to leak out and preventing intense heat bursts.
Researchers discovered that Valacyclovir can reduce HIV-1 levels independently of herpes infection, promising new avenues for drug development. The study's findings suggest the potential for a broader range of HIV-fighting drugs and could inform the design of new agents based on Valacyclovir's molecular structure.
Researchers at Benaroya Research Institute have discovered that chitin, previously thought to be absent in vertebrates, is endogenously produced in fishes and amphibians. This finding challenges longstanding biological assumptions and opens up new avenues for biomedical applications.
A study led by Massachusetts General Hospital investigators suggests that bariatric surgery can significantly reduce the risk of asthma attacks in obese patients. Significant weight reduction after surgery resulted in a half reduction in serious asthma-associated events, including emergency department visits and hospitalizations.
Researchers at the University of Arizona discovered how cells know to rush to a wound and heal it, shedding light on mechanisms of cell migration. They found that biomechanical stress and biochemical signaling orchestrate this process, which can be regulated and manipulated to create new tissues.
A study found that listening to classical music enhances gene activity related to learning, memory, and synaptic function, while down-regulating genes associated with neurodegeneration. Musically experienced participants showed the most significant effects, suggesting familiarity plays a key role in music-induced changes.