A recent study found that patients with inflammatory bowel disease (IBD) have a higher risk of heart failure hospitalization, with rates more than doubling during periods of activity. The research suggests that efficient IBD treatment may lower this risk, and highlights the need for cardiovascular risk assessment in these patients.
Researchers at Imperial College London have discovered a way to physically prove a 1934 theory that turned light into matter by smashing two particles of light together. The 'photon-photon collider' experiment uses existing technology to recreate a process important in the universe's first 100 seconds.
A new study suggests that a natural limiting switch exists in ocean systems, preventing the development of unchecked hypoxic areas. This cutoff switch is triggered by the formation of iron sulfides when oxygen levels approach zero.
A laboratory study found that e-cigarette vapor increases the virulence of drug-resistant bacteria like MRSA, making them more resistant to human cells and antibiotics. However, e-cigarettes also decrease the ability of human epithelial cells to kill these bacteria.
Scientists found that inhibiting COX-2, an immune protein causing inflammation, eliminated recurrent urinary tract infections in mice. COX-2 inhibitors, such as ibuprofen, showed promise in reducing susceptibility to repeat infections without increasing future risk.
Researchers from Loyola University Chicago found bacteria in the bladders of healthy women, challenging the common belief that normal urine is sterile. The study also revealed differences in bladder bacteria between healthy women and those with overactive bladder (OAB), which may contribute to OAB symptoms.
Two drugs, pirfenidone and nintedanib, have been found to slow the progression of idiopathic pulmonary fibrosis, a fatal lung disease. Researchers conducted multicenter clinical trials to test their efficacy.
New indicators of social and environmental well-being are being used to measure a nation's success beyond Gross Domestic Product (GDP). These include birth weight, hours slept, eyeglasses, city birds, washing machines, and teenage schoolgirls, highlighting the need for broader measures of societal progress.
A new study suggests that a simple urine test can detect blood clots in patients at risk, offering advantages over existing screening methods. The test evaluates fibrinopeptide B levels in urine, which are released when a thrombosis forms and then cleared by the body.
A study published in JAMA found that sepsis is a major contributor to hospital mortality, with approximately 1 in 2 to 3 deaths attributed to the condition. Most patients who died from sepsis had the condition present at admission. The study highlights the need for improved standardized care for patients with less severe sepsis.
The RELAX-AHF trial found that poor diuretic response is associated with worse in-hospital and post-discharge clinical outcomes. Patients who do not respond well to diuretics have less relief from dyspnoea and a higher risk of cardiovascular death or rehospitalisation.
A study presented at the Heart Failure Congress 2014 found that sleeping pills prescribed to heart failure patients with preserved ejection fraction (HFpEF) increase their risk of cardiovascular events. The study also showed that HFpEF patients who were prescribed high blood pressure medications had a lower risk of cardiovascular event...
Heart failure is a leading cause of hospital admission, particularly in older adults. The RELAX-AHF study found that worsening symptoms (worsening heart failure) during hospitalization can lead to longer stays and increased risk of readmission or death. Targeting worsening heart failure may help reduce these adverse outcomes.
Researchers at Mount Sinai present landmark studies on an immune response in prostate cancer tumors, effects of paternal age on live birth rates and treatment modalities for benign prostatic hyperplasia. The studies demonstrate complexities of immunotherapy and its impact on survival rates and fertility outcomes.
A study by Henry Ford Health found that 77 percent of super-frequent ED users have a substance abuse addiction. Researchers also discovered that pain-relief narcotics were the most commonly abused substances among women. Implementing case management strategies and funding for substance abuse programs may help alleviate the problem.
A new study shows that negative iron balance is a common occurrence in patients with acute heart failure and is associated with higher mortality rates. The researchers propose a new measure for iron deficiency, which takes into account both stored and utilised iron levels.
Researchers have discovered biomarkers that can detect Peripartum Cardiomyopathy (PPCM), a life-threatening disorder in pregnant women, allowing for early treatment and a significant reduction in mortality. The test aims to differentiate PPCM from normal pregnancy symptoms, enabling timely intervention.
A new glasses-free 3D projector design uses multiperspective technology to provide a cheaper alternative to holographic video, improving resolution and contrast. The system can also enhance conventional 2D video with increased brightness and sharpness, making it an attractive transitional technology for content producers.
Acupuncture at Yongquan acupoints induced stronger neuronal activation than sham points, increasing synaptic activity in areas involved in conscious thought. This may explain the improvement of patients with disorder of consciousness.
Junior Professor Dr. Elisabetta Chicca and colleagues discover that imprecise digital and analog circuits are more efficient than precise ones in building artificial nervous systems. The study, published in Proceedings of the IEEE, reveals a new approach to designing autonomous cognitive systems with minimal power requirements.
The Skunk Fire in Arizona has grown to over 10,000 acres, driven by extremely dry fuels and low relative humidity. The fire is currently 20% contained and continues to spread to the north, with conditions making it difficult for firefighters to access the area.
A recent study found a significant correlation between US foreclosure crisis and rising suicide rates, especially among middle-aged adults. Foreclosures were found to affect not only individuals but also entire communities, exacerbating feelings of loss, shame, or regret.
The study found lung cancer rates declining in 47 of 52 populations among young women (30-49 years), while increasing in most countries among older women (50-74 years). Tobacco control efforts and increased awareness have contributed to the decline, but more needs to be done to curtail future deaths.
Researchers at Penn State will focus on developing plasma photonic crystals and plasma-embedded metamaterials that operate in the terahertz range, enabling applications such as antennas with beam steering and filter devices. The project aims to replace traditional metallic split-ring resonators with low-loss dielectric resonators.
Researchers urge caution when exploring/exploring the deepest parts of our oceans, highlighting the need for a 'happy balance' between use and environmental costs. The deep ocean is already experiencing impacts from human activities such as fishing, oil and gas development, and waste disposal.
Dr. Neal Meropol, Chief of Hematology and Oncology at Case Western Reserve University, is honored as an ASCO Fellow for his exceptional volunteer service and dedication to cancer care. He has served on the ASCO Board of Directors and various committees, contributing to the organization's mission to improve cancer care.
A study published in JAMA Surgery found that patients who underwent ureteroscopy had fewer repeat treatments and lower costs compared to those who received shock wave lithotripsy. The researchers suggest that the decision to choose one procedure over the other should be carefully considered by both doctors and patients.
Scientists have developed an early warning system to predict dengue infections for Brazil's 553 microregions during the football World Cup. The system estimates little risk of dengue outbreaks in southern and central capitals, but predicts a moderate risk in Rio de Janeiro and Salvador.
Researchers validated microbial translocation hypothesis in SIV-infected pigtail macaques, finding that sevelamer treatment reduced systemic LPS and activated peripheral CD4+ T cells. Sevelamer also lowered viral titers and coagulation biomarkers, suggesting a potential therapeutic strategy for HIV.
Caswell's work on matrix population models has had a significant impact on life history theory, conservation biology, climate studies, and the evolution of aging. He was recognized for his lifetime contributions to mathematical demographic analysis.
Researchers found that repeated-pulse transcranial magnetic stimulation at the Guangming point evokes distinct patterns in electroencephalogram signals compared to other nearby points. This study suggests a potential therapeutic application of this stimulation technique for modulating brain activity.
Researchers at Princeton University have discovered a new class of quantum materials that enable electrons to flow through the interior with minimal resistance. This breakthrough has significant implications for future technologies, including faster electronics and quantum computing.
Seven wildfires are still burning in San Diego County, California, with the Cocos Fire being the most active, spanning over 1,200 acres. The region is experiencing extreme drought conditions, and climate change is cited as a factor by the governor.
A study found that people enrolled in methadone treatment programs are receptive to HCV education and treatment. The research suggests that these facilities can provide sustained HCV treatment by linking care to substance abuse treatment, leading to improved adherence.
A recent study published in Human Reproduction found that men with male infertility are more likely to die sooner than those with normal semen quality, with a doubling of mortality risk. The study examined data from over 12,000 men aged 20-50 and found an inverse relationship between semen quality and mortality rate.
A new transgenic mouse model produces both essential omega-3 and omega-6 fatty acids on a carbohydrate diet. The Omega mouse has been bred to produce mice that express both genes, leading to significant increases in omega-3 levels and decreases in omega-6, with implications for human health.
The University of Louisville has received a three-year, $5.5 million grant from the Leona M. and Harry B. Helmsley Charitable Trust to develop new treatments and vaccines for various forms of cancer. Researchers will focus on plant-based pharmaceuticals and vaccines for cervical and colon cancer.
The Autism BrainNet consortium will collect, store and distribute brain tissue resources to understand the neurobiology and genetics of autism. Researchers have made important discoveries using donated brain tissue, showing structural differences in autistic brains and changes in gene expression.
Researchers developed herpes-loaded stem cells that significantly improved survival rates in mice with glioblastoma multiforme when applied to tumors. The treatment used mesenchymal stem cells as drug delivery vehicles, allowing oncolytic viruses to replicate and kill residual cancer cells.
Researchers found that acrylamide exposure damages the blood-cerebrospinal fluid barrier and impairs secretory and transport functions. This damage may underlie acrylamide-induced neurotoxicity and central and peripheral neuropathy.
Researchers have identified a new microRNA, hsa-miR-765, that suppresses expression of HMGA1 in prostate cancer cells, offering potential as a targeted therapy. The microRNA is activated by an FDA-approved anti-estrogen drug, fulvestrant.
A study by researchers at Stanford University reveals fundamental differences in parenting methods between Asian Americans and European Americans. Asian American 'tiger mothers' motivate their children through interdependence, allowing them to draw on connectedness with their mother for motivation. In contrast, European American parent...
A study found that young adults who smoked water pipes in hookah bars had significantly elevated levels of nicotine, cotinine, and tobacco-related cancer-causing agents in their urine. This may increase their risk for cancer and other chronic diseases.
Researchers found sildenafil's benefits for female mice modeling human heart failure varied with estrogen levels, but were generally ineffective. In contrast, male mice showed improved cardiac health due to sildenafil's effects on cGMP pathways independent of estrogen.
Adding camelina or safflower to crop rotations with winter wheat and summer fallow increases wind erosion risk in the Pacific Northwest. No-till fallow or planting another crop without a fallow year can help control blowing dust.
Researchers have published a study providing complete open access to detailed 3-D images of earthworms, enabling the analysis of rare museum specimens. The study uses micro-computed tomography (microCT) to digitize worm structures, opening possibilities for scanning millions of specimens from museum collections.
Researchers identify two new bacterial causes of pneumonia in chamois, highlighting risk of inter-species transmission with domestic animals. The combination of parasite infestation and harsh winter conditions weakened the immune systems of the affected animals.
Berkeley Lab researchers have developed a technique to modify graphene boron nitride heterostructures using visible light, preserving high electron mobility. This method enables p–n junctions and flexible doping profiles without sacrificing material quality.
A new method of making super tough fibers could be achieved by adding a slip knot to absorb additional energy, increasing its toughness from 44 to 1070 Joules per gram. The new approach allows ordinary polymers to reach unprecedented levels of resistance.
Researchers discovered that CCL28 and its receptor are key players in angiogenesis, a hallmark of rheumatoid arthritis. This finding provides strong evidence for the binding of CCL28 to joint-lining cells as necessary for blood vessel formation.
The Dresden 5G Lab, a collaboration between Technische Universität Dresden and over 500 scientists, aims to develop key technologies for the 5th generation of mobile communications. The lab will focus on reducing latency and increasing throughput, with applications in industries such as transportation, healthcare, and education.
A high school student's project found significant increases in nicotine on surfaces after vaping, even if the user wasn't exposed to the e-cigarette. The study also explored cognitive control in multitaskers and identified potential medications for various diseases.
University of Utah researchers developed a way to observe HIV budding without interfering with the process, showing ALIX's involvement in the late stages of virus replication. The study used digital camera and microscope technology to make movies and photos of the budding process.
Women who participated in a 5-week cognitive behavioral training program showed significant improvements in mood, emotional well-being, and stress management skills. The Relaxation Training group also reported reduced disruptions in social activities and increased confidence in using relaxation techniques.
Researchers found that mindfulness training can help Marines recover from stressful combat situations by reducing heart and breathing rates. The study suggests that incorporating meditative practices into pre-deployment training might be a way to reduce stress-related health conditions in the US military.
Between 2002 and 2012, magnet ingestions by children tripled in number and nearly doubled in severity, with a significant increase in high-risk injuries featuring multiple smaller magnets.
Rice University physicist Wei Li is searching for the smallest and hottest drop of 'quark soup' in the universe, a liquid of subatomic particles that only appears at temperatures above 2 trillion kelvins. He will use the world's most powerful particle accelerator, LHC, to study quark-gluon plasma.
The UT Arlington particle physics team has been awarded a $2.5 million, three-year Department of Energy grant to continue their work on the ATLAS experiment at the Large Hadron Collider. The grant represents a 25% increase in funding and recognizes the team's innovative ideas and research.
The Phase 3 trial demonstrated positive trends in lung function, as measured by relative change in % predicted FEV1, with a 2.5% average difference between ataluren and placebo in favor of ataluren. Additionally, there were 23% fewer pulmonary exacerbations in the ataluren group compared to placebo.
A recent study by the University of Pittsburgh Center for Vaccine Research has provided direct evidence of a major culprit behind poor outcomes for some HIV-infected individuals. The research suggests that blocking bacterial translocation can significantly slow HIV progression and reduce comorbidities such as heart disease.