A study of 41 untrained women aged 35-50 with mild high blood pressure found a significant reduction in blood pressure and body fat percentage after 15 weeks of football training. The researchers also found that women like playing football even if they have no previous experience, leading to the creation of their own football club.
Researchers from LLNL and MIT have created ultra-lightweight and stiff mechanical metamaterials using additive micro-manufacturing processes. The new materials exhibit properties not found in nature, maintaining a nearly constant stiffness per unit mass density across more than three orders of magnitude in density.
Researchers discovered a genetic partnership between KRAS and YAP1, enabling cancer cells to survive in the absence of KRAS. This 'escape mechanism' must be blocked alongside shutting down oncogene KRAS to kill tumor cells.
Researchers have identified skulls with a mix of Neandertal and primitive traits, providing new insights into human evolution. The findings support the accretion model hypothesis, suggesting that Neandertals developed their defining features in stages, not all at once.
A 6200-year-old schistosomiasis parasite egg discovered in Syria's Tell Zeidan grave suggests ancient agricultural irrigation systems may have spread the disease. The find, dating back a thousand years earlier than previous discoveries, highlights how human technology can exacerbate disease burdens.
The International Space Station's third annual research conference recognized three notable technology applications in 2013. The SPHERES-Slosh investigation demonstrated improved spacecraft designs by simulating fluid movement in microgravity, while a laser communication system was tested for high-speed transmission between the space s...
Researchers at Weizmann Institute identify microRNA molecule miR135 linked to serotonin system and its role in depression and anxiety disorders. Higher levels of miR135 found in healthy mice resistant to chronic stress, while low levels associated with depressed behavior and weaker response to antidepressants.
A study by Penn Medicine researchers found a common genetic link among patients with pemphigus vulgaris, a blistering skin disease. The researchers identified a particular gene, VH1-46, that was used by PV antibodies across all four patients, suggesting common mechanisms for developing the disease.
Researchers have developed a new monkey model for AIDS using pigtailed macaques, which can cause full-blown AIDS in primates. The model allows for the study of HIV-1's interaction with host antiviral defenses and has the potential to improve prevention and treatment research.
A computer-designed protein, BINDI, was engineered to trigger self-destruction of Epstein-Barr-infected cancer cells. It suppressed tumor growth and enabled mice with EBV-positive lymphoma to live longer.
The BICEP2 collaboration has published nuanced findings on microwave sky patterns, suggesting possible primordial gravitational waves. However, they acknowledge the presence of galactic dust as a potential explanation for the signals.
A susceptibility gene for type 1 diabetes has been found to regulate self-destruction of the cell's energy factory. Researchers discovered that this pathway could be targeted for prevention and control of type-1 diabetes and may extend to treatment of other metabolic-associated diseases.
Research from the University of Texas MD Anderson Cancer Center found that African American women with early-stage invasive breast cancer were 12% less likely to receive axillary sentinel lymph node biopsy, a minimally invasive technique. The study also showed that those who received older, more invasive axillary lymph node dissection ...
Researchers have discovered a rapidly moving gas streamer blocking X-rays from the galaxy's nucleus, indicating a significant decrease in radiation. This phenomenon may regulate the growth of both the supermassive black hole and its host galaxy.
A study analyzing 563,281 hemodialysis patients found significant racial and ethnic differences in hospitalization rates. Younger black patients, older black patients, and older Hispanic patients had increased hospitalization rates compared to whites of similar ages, highlighting the need for targeted interventions.
A team of researchers has developed an algorithm that can determine whether a video is running forward or backward with 80% accuracy. The algorithm analyzes subtle visual cues and identifies regions of frames to make its judgments, potentially leading to more realistic graphics in gaming and film.
A growing number of colorectal cancer deaths in Europe necessitates an increase in nurse endoscopy training, with regular screening reducing the risk by 20-30%. UEG and ESGENA are working together to standardize training requirements and improve workforce availability.
Researchers at Albert Einstein College of Medicine will study how breast cancer cells move and spread in the body. They aim to develop a test that predicts which breast cancer tumors will metastasize, based on the presence of a trio of cells called a tumor microenvironment of metastasis.
Researchers have developed a clinically relevant mouse model for squamous cell lung cancer, driven by the misregulation of genes sox2 and lkb1. The discovery uncovers new treatment strategies and provides insights into potential targeted therapies.
Researchers at Princeton University used a computer model to explore water as it freezes, finding that it can exist in two liquid phases of different densities. The dual nature of water could lead to better understanding of how it behaves at cold temperatures found in high-altitude clouds.
The US is facing a severe shortage of cybersecurity professionals, with demand far outpacing supply, particularly in the federal government. The RAND Corporation study calls for reforms, including waiving civil service rules and increasing funding for education programs to address the issue.
Researchers estimate that medication management and counseling by a pharmacist can reduce readmissions by up to 20%. The study, funded by the National Association of Chain Drug Stores Foundation, pairs high-risk patients with community pharmacists to review medications and provide guidance on managing complex disease states.
Researchers mapped a gene variant among Greenlanders that markedly increases the risk of developing type 2 diabetes. The gene variant is primarily found in Greenlanders and explains 15% of cases in the country.
A study found that stories praising honesty, such as the tale of George Washington, inspire children to tell the truth. In contrast, cautionary tales like 'The Boy Who Cried Wolf' had no effect on honest behavior.
The SHINES project, led by UC Riverside Professor Jing Shi, will investigate new ultrathin films, nanostructured composites, and electrical signal transport. The four-year project aims to advance fundamental advances in energy production, storage, and use.
A new study suggests that bipolar children have unique brain activity patterns compared to adults, particularly in emotional face recognition and cognitive tasks. The research provides insight into potential targeted treatments for pediatric bipolar disorder.
Empa researchers have developed a microstructure that gathers sunlight on the photoelectrode surface, allowing it to absorb all the energy in the beam. This innovative structure is inspired by the eyes of moths, which collect as much light as possible while reflecting as little as possible.
Research reveals that nearly 70% of females ages 15-19 live away from their native villages, leading to a significant outmigration of young people from the highlands. This trend threatens to create graying ghost towns at the top of the world, with population decline predicted to reach 50-60% in the next five decades.
Researchers developed a new, non-destructive method to identify many types of inks on various papers and surfaces. The tip-enhanced Raman spectroscopy (TERS) technique can analyze organic colorants with high sensitivity and spatial resolution, making it suitable for preserving valuable cultural heritage treasures.
Researchers have discovered a new concept for particle separation, leveraging horizontal levitation of non-magnetic particles in a magnetic field. The technique exploits differences in density and magnetic susceptibility to separate glass and pyrite particles.
Researchers found that aircraft can contribute less to global warming by flying routes that avoid forming distinctive condensation trails, or contrails. By doing so, they emit more carbon dioxide but may have a smaller overall climate impact due to the cooling effect of contrails.
A randomized trial found that telephone-based weight loss advice reduced breast cancer recurrence risk by lowering weight and inflammation. Postmenopausal women with breast cancer who received lifestyle coaching via phone achieved comparable sustained weight loss to in-person consultations.
Understanding the structure and movement within molecular factories in microorganisms enables researchers to design and engineer systems for producing novel drugs. The discovery provides a blueprint for redesigning microbial assembly lines, holding promise for developing new medicines.
A study found that over 50% of minors have exchanged explicit text messages, with most unaware of the legal ramifications. Researchers highlight the need for education and specific laws to address this issue. The study revealed a significant relationship between awareness of legal consequences and sexting behavior as minors.
Families whose first child was diagnosed with autism spectrum disorder had lower birth rates compared to control families. Women who changed partners also experienced a stronger reduction in reproductive behavior.
Researchers developed a novel theory of how neurons work together during complex movements, revealing a balance between excitatory and inhibitory signals. The new model can accurately reproduce multidimensional movement patterns and may aid in the understanding of brain dynamics.
Researchers have developed a technique to produce soft machines made of elastic materials and liquid metals using a custom-built 3D printer. The technique enables the creation of strain gauges that can detect high strains and deform with almost any material, making it suitable for wearable technology and sensory skin.
The new journal, Research in the Mathematical Sciences, covers applied math, pure math, and theoretical computer science. It aims to publish high-quality original articles and seminal papers on emerging areas of mathematical research.
Two low-cost, car battery-sized Canadian nanosatellites are part of the BRITE-Constellation project, monitoring brightness and color variations of brightest stars. The satellites will uncover clues about star origins, including our Sun and Earth.
Researchers have discovered hundreds of non-coding RNAs in the developing and adult lungs that regulate gene expression by controlling DNA scaffolding. These 'genomic dark matter' RNAs, including NANCI and LL34, play critical roles in lung development and may underlie human diseases such as Brain-Lung-Thyroid Syndrome.
A new study suggests that blocking endocannabinoids, the brain's internal versions of marijuana's psychoactive chemicals, may trigger early Alzheimer's deficits. A-beta, a substance strongly suspected to play a key role in Alzheimer's, impairs learning and memory by blocking endocannabinoids' beneficial action in the brain.
A neuroscientist proposes a novel explanation for habituation, which allows the brain to filter out insignificant environmental stimuli. The 'negative-image model' explains how repeated activation of neurons leads to increased inhibition, altering responses in individuals with autism spectrum disorders.
A new study reveals that astrocytes can monitor and respond to nearby neural activity, but only when primed by the fight-or-flight chemical norepinephrine. This ability suggests that astrocytes may help control the brain's ability to focus.
The article highlights the persistent issues with STEM pipeline diversity, citing data showing that underrepresented minority students are less likely to graduate and enter STEM careers. Researchers Andrew G. Campbell and Stacy-Ann Allen-Ramdial propose four ideas to improve the pipeline, including aligning culture and climate, partner...
A study by Harvard Medical School found that antidepressant prescriptions for young people dropped after FDA warnings, leading to a relative increase in suicide attempts. The researchers suggest that better communication between the FDA, media, and physicians is needed to ensure patients receive appropriate treatment.
A new study published in Menopause found that calcium and vitamin D supplements can lead to high levels of calcium in the blood and urine in some older women. The risk was higher for those with lower initial calcium levels and increased age.
Researchers at the University of Leicester discovered that human sweat can corrode brass objects' antimicrobial properties within an hour of contact. This corrosion reduces their effectiveness in killing bacteria and other microorganisms.
The war on terror is incorporating medicine into warfare, undermining population health and exacerbating global health inequities. Humanitarian and health workers face profound moral distress due to being treated as tools in the war on terror.
Scientists at Southeast University propose a scheme to control optical steady behavior in GaAs quantum well structures via nonradiation coherence. The study reveals multi-stability and optical bistability, with the ability to convert between these states by adjusting phase differences in polarized electric fields.
The I-Corps at NIH pilot program aims to train business-minded biotech researchers to evaluate their scientific discoveries for commercial potential. The program will provide tools and resources to prospective entrepreneurs, including real-time interactions with potential customers and supplemental funding.
A recent study by Dartmouth-Hitchcock Norris Cotton Cancer Center found that 22 out of 552 women had their tumor type incorrectly classified using conventional HER2 testing. The study confirmed the importance of accurate HER2 testing, as incorrect classification can have significant implications for treatment decisions.
Researchers at Harvard University discovered that many birds targeted by the Common Cuckoo have evolved recognizable egg patterns to distinguish their own eggs from those laid by cuckoo cheats. These signatures provide a strong defense against cuckoo mimicry, helping host birds reject foreign eggs and protect their broods.
A UCSF study found that families with an autistic child are one-third less likely to have more children. The study analyzed California state health records and found that reproductive stoppage, or the decision not to have more children due to a genetic disorder, is a real phenomenon.
Researchers have discovered a new quantum mechanism that triggers the emission of tunable light at terahertz frequencies, enabling unprecedented efficiency. This breakthrough uses asymmetric 2D nanostructures to enhance light emission in a challenging spectral range.
Research from UT Southwestern Medical Center found that a level of 'healthy' inflammation is necessary to prevent fatty liver and metabolic diseases. Inflammation helps remodel fat tissue, preventing the buildup of excess lipids in other tissues.
A new study published in Neurology suggests that group doctor visits can benefit individuals with muscle diseases, improving their quality of life. Participants who received group visits scored higher on a quality of life test compared to those who had individual appointments.
Researchers discovered the protein SerRS acts as a brake on new blood vessel growth and pairs with c-Myc to promote proper vascular development. The study found that SerRS suppresses VEGFA transcription by recruiting SIRT2, a partner enzyme that had never been linked to angiogenesis.
Researchers have developed laser-written light-guiding systems for efficient commercial use. The technology allows embedding sensors, including temperature and biometric sensors, into Gorilla Glass to create new real estate in phones. This could enable secure transactions using infrared light and more compact devices.
Researchers at UEA identified a vulnerable gate in Gram-negative bacteria's outer membrane that prevents the transport of barrier-building blocks, making bacteria susceptible to death. This breakthrough could lead to new generation drugs targeting the protective barrier instead of the bacteria itself.
The Columbia Engineering team found a critical security problem in Google Play, where developers store their secret keys in their apps, making them vulnerable to malicious attacks. The discovery was made using a new tool called PlayDrone, which downloaded over 1.1 million Android apps and identified thousands of secret keys.