The Affordable Care Act (ACA) offers significant benefits for diabetes patients, including non-exclusion of pre-existing conditions and access to preventive services. The law also authorizes the creation of the National Diabetes Prevention Program, delivering evidence-based lifestyle change programs to prevent type 2 diabetes.
Researchers at the University of Cincinnati have discovered a therapy that reverses new onset Type 1 diabetes in mouse models. The treatment targets the innate immune system and boosts activity of TLR4, preserving insulin-producing beta cells. This approach may hold promise for treating Type 1 diabetes in humans.
A post-hoc analysis of patients with type 2 diabetes found that intensification of insulin therapy with Januvia (sitagliptin) 100 mg once-daily resulted in lower incidence of nighttime hypoglycemia compared to placebo. This is a positive finding for treatment approaches aimed at lowering nocturnal hypoglycemia.
A study published in Diabetes Care found that a diet rich in canola bread resulted in reduced blood glucose levels and significant reductions in LDL cholesterol. The benefits were most pronounced for those with the highest HbA1c scores, suggesting that canola oil may be a valuable addition to treatment plans.
A retrospective cohort study found patients taking JANUVIA and metformin initiated insulin therapy at a slower rate than those taking a sulfonylurea and metformin. The study suggests that real-world data may provide insight into the effects of different oral treatment regimens on the initiation of insulin use.
Researchers found that periodic fasting can convert bad cholesterol in fat cells to energy, reducing the risk of diabetes and metabolic problems. After 10-12 hours of fasting, the body starts scavenging for other sources of energy, pulling LDL cholesterol from fat cells and using it as energy.
A study found that improving diet quality by 10% over four years reduced the risk of type 2 diabetes by about 20%. This benefit was independent of other lifestyle changes such as weight loss or increased physical activity. Improving diet quality alone has significant health benefits.
A new theory proposes that stimulating mitochondrial function and superoxide production can improve markers of renal, cardiovascular, and nerve dysfunction in diabetes. This approach may help promote tissue healing and is linked to improved outcomes for diabetic kidney disease.