Scientists at the University of Birmingham have identified a mechanism that led to some patients experiencing deadly clotting following Covid-19 vaccination. The team found that Platelet factor 4 (PF4) activates the c-Mpl-Jak2 pathway in platelets, triggering clot formation.
Researchers developed an environmental risk score to assess ALS risk and survival using a blood sample, associating several individual pollutants with disease risk. A mixture of pesticides in the blood significantly increased ALS risk, with those in the highest group having twice the risk as those in the lowest.
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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A new study published in JAMA Network Open found time-restricted eating to be safe and effective for people with Type 2 diabetes, helping them lose weight and control blood sugar levels. Participants who followed the time-restricted eating plan had an easier time sticking to it than those on a calorie-reduced diet.
A recent study by the University of Gothenburg found no correlation between post-COVID condition and ongoing viral infection or active brain damage. The study analyzed 25 participants with confirmed post-COVID condition, six without residual symptoms, and 17 control subjects, revealing undetectable SARS-CoV-2 antigens in all samples.
A new study published in the University of East Anglia shows that automated insulin delivery technology can help pregnant women with type 1 diabetes better manage their blood sugars. The technology, known as Hybrid Closed-Loop or Artificial Pancreas, helps to substantially reduce maternal blood sugars throughout pregnancy.
A new neighborhood-based care model has been shown to be effective in treating hepatitis C among injection drug users and those experiencing homelessness. The study found that 92% of participants had undetectable levels of the virus after treatment, with 84% achieving sustained virologic response.
The Center for Advancing Point of Care Technologies (CAPCaT) has received a five-year, $8.9 million award from the NIH to develop innovative point-of-care health technologies. The program aims to address heart, lung, blood and sleep disorders in underserved populations.
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers mapped mosquito's tree of life, revealing how the insects chose their hosts and evolved disease transmission. The findings suggest mosquitoes started out feeding on amphibians and later moved to other groups as they flourished.
A new AI tool developed at Vanderbilt University Medical Center accurately identified pediatric patients at high risk for blood clots. However, the study found no difference in outcomes between the treatment and control groups, suggesting that clinicians may need to overcome reluctance to accept blood-thinning therapy recommendations.
A smart brain-wave cap can diagnose stroke in ambulances, allowing for prompt treatment and potential lifesaving. The cap uses EEG tests to recognize large ischemic strokes, directing patients to specialized hospitals for mechanical removal of blood clots.
A new technique to control severe bleeding in injured patients has been found to increase the risk of death. The REBOA treatment was tested in a clinical trial involving 90 adult trauma patients, but it did not show the expected benefits.
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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A new blood test has been developed to measure the levels of critical omega-3 fatty acids in the bloodstream, providing a convenient way to assess cardiovascular and cognitive health. The Omega-3 Index (O3I) is derived from two key fatty acids, EPA and DHA, which can be obtained only from certain dietary sources.
Red blood cell transfusions were common in ICU patients globally, with overlapping reasons for use despite differing clinical contexts. The three most common triggers for transfusion (hypotension, tachycardia, hemodynamic instability) were largely consistent across regions.
A new study found that hybrid closed-loop technology significantly improved maternal blood sugars in pregnant women with type 1 diabetes. Women who used the technology spent more time within the target range for pregnancy blood sugar levels, gained less weight, and had fewer complications.
A new American Heart Association advisory introduces the concept of cardiovascular-kidney-metabolic (CKM) syndrome, which affects nearly every major organ. The approach highlights the importance of screening for CKM-related conditions and addressing social factors to prevent progression.
Researchers have developed a human vascular organoid model that accurately mimics the damage caused by SARS-CoV-2, revealing clues for a potential COVID-19 treatment. The study identified a long-acting monoclonal antibody targeting factor D as a promising approach to mitigate severe vascular damage and thrombosis associated with COVID-19.
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Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
Researchers developed a low-cost, ultrasensitive blood test to detect a highly specific biomarker for multiple common cancers. The test showed promise for early cancer detection and disease monitoring, detecting levels of the biomarker in the blood of patients with many types of cancers.
A large-scale clinical study confirms the validity of the Vienna Prediction Model in identifying low-risk patients with venous thromboembolism who may not require long-term blood thinning. The model's accuracy was found to be 5.2% after one year for patients with a low relapse risk, but adjustments were made to correct imprecision.
Researchers have developed a wearable sensor patch capable of continuously monitoring vancomycin levels, a critical antibiotic used to treat severe bacterial infections. The sensor system detects changes in vancomycin concentration using aptamers and gold wires, providing real-time measurements for effective treatment.
Researchers developed a new technology to test new drugs against liver diseases by recreating the real human liver environment. The model consists of live liver cells in an artificial blood vessel system, allowing for controlled testing and monitoring.
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A significant breakthrough sheds light on Parkinson's disease mechanisms, revealing that mitochondrial DNA damage triggers the spread of debilitating symptoms. The researchers' findings offer promising potential for innovative treatments and diagnostics.
A new approach is being developed to identify sepsis in newborn babies, with the potential to transform sepsis testing. The Neosepsis project aims to reduce neonatal deaths in Uganda by providing a quick and reliable test using a small drop of blood.
A pharmacist-led intervention has been shown to improve medication adherence among Latinos with type 2 diabetes, leading to significant reductions in blood sugar levels. The study found that patients who interacted with a pharmacist had an average 0.45% reduction in blood sugar, while systolic blood pressure remained unchanged.
A large study of 74,471 patients found that those who quit smoking after percutaneous coronary intervention (PCI) have comparable rates of heart attacks, strokes, and deaths to non-smokers. However, heavy smokers showed no improvement in cardiovascular outcomes.
Over 75% of hospitalized AKI patients lack proper follow-up kidney health testing after discharge. Less than 25% have kidney function monitored with blood and urine tests within 90 days of discharge.
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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A new study from Uppsala University has found that women with a high genetic predisposition for blood clots are six times more likely to develop a blood clot during the first two years of using contraceptive pills. This knowledge could be used to identify women at risk and counsel them on alternative methods of contraception.
A study of 20,048 British-Bangladeshi and British-Pakistani women found that those with the Factor V Leiden gene mutation who used oestrogen had more than double the risk of blood clotting. The presence of obesity, high blood pressure, high cholesterol, and kidney disease significantly increased this risk.
A new study found that only one out of four recommended screening tools for sepsis is reliable, with NEWS-2 accurately predicting 72.2% of all sepsis cases. The study also highlights the need for better awareness and more frequent use of effective screening tools to improve early sepsis recognition and survival rates.
Dr. Hung Nguyen is studying how medium chain fatty acid foods like coconut oil and avocados affect GVHD severity and mortality in transplant patients. His goal is to develop a dietary approach that reduces inflammation and corticosteroid use, improving patient outcomes for blood cancers.
A study at the Technical University of Munich found that people with long Covid experience altered blood vessels in the eye, which could be used to diagnose the condition. Persistent inflammatory responses were also linked to symptom severity and chronic inflammation.
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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A new study suggests that cerebral amyloid angiopathy (CAA), a common cause of spontaneous brain hemorrhages, can be transmitted via blood transfusion. Patients who received blood from donors with CAA were more than twice as likely to suffer a brain hemorrhage themselves.
Researchers found that patients with HPV-positive cancers develop recurrent disease significantly later than those that were HPV-negative, and also are more likely to spread to the lungs. A new, highly sensitive blood test has been developed to detect cancer earlier, using a framework for combining routine blood testing and imaging.
Researchers found that pregnant mice experiencing copy number variation (CNV) showed similarities to aging, with biomarkers and genetic effects appearing during pregnancy and reversing after delivery. This study aims to revolutionize aging treatment by investigating the mechanisms behind post-labor rejuvenation.
Patients taking non-selective beta-blockers for knee pain have a 54% reduced risk of undergoing total knee arthroplasty. Prolonged use and high adherence to treatment also showed strong protective effects.
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Researchers discover compound Urolithin A restores mitochondrial function in hematopoietic stem cells, rejuvenating blood reconstitution capability and improving immune system function. The study shows promising results in aging mice, paving the way for potential interventions targeting age-related health conditions.
A Michigan Medicine study found that pulmonary embolism death rates remained unchanged over the past decade, with higher mortality rates among men, Black patients, and those from rural areas. The study analyzed over 100,000 deaths related to pulmonary embolism between 2006 and 2019.
Research at Columbia University's Mailman School of Public Health detected significant levels of metals in the blood and urine of marijuana users, suggesting that marijuana is a source of lead and cadmium exposure. Measurements reported by participants showed higher lead levels in blood and urine among exclusive marijuana users compare...
A nationwide study found that modern blood thinners (NOACs) reduce the risk of serious bleeding by up to 45 percent compared to traditional drug Waran. Apixaban, a NOAC substance, is associated with a lower risk of bleeding in both short and long-term treatment.
Researchers have identified four specific factors that can predict atrial fibrillation, a condition that increases stroke risk by up to five times. The team developed an easy-to-use tool for doctors to identify high-risk patients, which may lead to targeted treatment and reduced future strokes.
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Researchers found a significant increase in pediatric trauma admissions during the COVID-19 pandemic, with younger patients and falls from moderate heights being more common. Blood alcohol levels were also higher in patients aged 14-18 years old, suggesting targeted interventions to curb alcohol use may be needed
A new study from Texas A&M University finds a correlation between secondhand smoke exposure and higher blood lead levels in children. The research suggests that education and mitigation efforts can further protect kids and adolescents from lead exposure, building on past success of lead removal initiatives.
Scientists have identified platelet factor 4 (PF4) as a common messenger for the cognitive benefits of young blood transfusion, exercise, and the longevity hormone klotho. Studies show that PF4 calms down the aged immune system, reducing inflammation and promoting brain plasticity and cognition.
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Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers analyze ancient documents to shed light on the health of Vlad III, the legendary inspiration behind Count Dracula. The study reveals potential signs of respiratory problems and a condition that could have caused him to cry blood.
Researchers examine translational studies on peripheral surrogates of tumor burden, including circulating tumor DNA, miRNA, and HPV-specific antibodies, to inform chemotherapy and immunotherapy strategies. These biomarkers show promise as prognostic and predictive markers of response to treatment.
Researchers at West Virginia University are tracing the cause of diabetic heart disease using diabetic animal models to examine mitochondrial function. They hope to understand how faulty protein import affects the mitochondria and explore potential treatments to improve energy production and reduce cardiovascular risk.
Researchers have made a significant discovery in gene therapy, showing that genetically engineered blood stem cells can be created while still in the bone marrow. This approach eliminates the need for chemotherapy and transplantation of corrected cells, cutting costs and improving access to critical treatments.
Research by the Peter Doherty Institute found that inflammation alters plasma composition, hindering parasite maturation. This work reveals a new mechanism slowing down malaria parasite development in the bloodstream.
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A team of researchers developed a novel method that leverages temporal characteristics of blood pulse to estimate heart rates with improved accuracy, especially in scenes with ambient light fluctuations. The proposed method showed a 36.5% improvement in estimation accuracy compared to conventional methods.
A new drug formulation designed for treating children with HIV has shown safety, tolerability, and effectiveness in a study published in The Lancet HIV. The formulation contains three medications and was found to suppress HIV levels below 200 copies/mL in 98% of participants.
Research analyzed seven international studies and found a continuous increase in blood pressure measures with both low and high alcohol intake. Low levels of alcohol consumption were linked to detectable increases in blood pressure levels, which may lead to a higher risk of cardiovascular events.
The study reveals altered magnitudes and coherence between oscillations in brain vasculature and brain waves in older adults. This finding has significant implications for the assessment of Alzheimer's disease and monitoring of neurodegenerative disorders.
Researchers developed a blood test to detect nerve injury in MS and found it works for children, even when symptom-free. The test measures neurofilament light chain levels, which reflect nerve cell injury.
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A new study from the University of Missouri found that poverty, low health literacy, cultural beliefs, lack of infrastructure, and political issues hinder diabetes self-management for Haitian migrants. The researchers suggest targeted interventions, such as community gardens and healthcare education through local priests.
Researchers develop a new technique to detect circulating tumor cells in blood, overcoming noise issues with existing methods. The dual-ratio approach enhances penetration range and accuracy, paving the way for quicker diagnosis of metastasis.
New studies show cow colostrum can reduce infant formula use and strengthen mother's milk in premature babies, providing essential nutrients like amino acids. Researchers hope to optimize cow colostrum product for critical first few weeks after birth.
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Researchers discovered bimetallic tartrate complexes with unique structures, formed by insufficient ligand, leading to improved sensor characteristics for microbiosensors. The study showcases the potential of laser-induced chemical liquid phase deposition for creating nanostructures with various applications.
A study published in Diabetes journal has discovered neurons in the brain that can detect and respond to changes in blood sugar levels. This discovery may help doctors reduce blood sugar levels in patients with diabetes by targeting these neurons.
Researchers at the University of Wisconsin-Madison found that ticks can harbor transmissible amounts of the protein particle causing CWD, potentially spreading the disease between deer. The study also suggests that better land stewardship and tick management could help manage CWD populations.
Researchers discovered that using fat-free mass for gentamicin dosage calculation yields more effective results than traditional methods. This method is particularly beneficial for premature babies, who have weaker kidneys and require adjusted dosing.
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A deep learning-based model developed in 7,105 patients predicted 30-day all-cause mortality in patients with CAP with AUCs ranging from 0.77 to 0.80. The model showed higher specificity than the CURB-65 score at the same sensitivity.