Articles tagged with Blood
A new study has identified alpha-1-antichymotrypsin as a blood protein marker that can predict delayed recovery of concussion in children. The study found that children with low levels of alpha-1-antichymotrypsin were more likely to experience delayed recovery, highlighting the potential for early diagnosis and targeted treatment.
Studies at the University of Gothenburg found a clear shift in arterial disease risks in diabetes, with decreases in central organ diseases like heart attack and stroke, but increases in peripheral vessel complications. Closer monitoring of long-term blood sugar levels can reduce peripheral arterial disease risk by 30-50%.
New data suggest that blood-based colorectal cancer screening tests could lead to more cases and deaths than established methods, despite improving outcomes for unscreened individuals. The tests are predicted to be less effective and more costly, making them unsuitable replacements for current screening programs.
Scientists have discovered six proteins that can accurately diagnose tuberculosis (TB). The breakthrough study paves the way for a simple blood test to detect the bacteria, which could prevent millions of cases annually. TB is the world's deadliest infectious disease, killing over one million people each year.
A multi-institutional team is creating innovative technologies to reduce complications associated with left ventricular assist devices (LVADs), including infection, thrombosis, stroke, and bleeding. The new LVAD will deliver a physiological response to changes in the recipient's activity levels using a 'smart' Maglev drive technology.
Researchers found that daily cranberry extract consumption for 28 days improved running speeds by 1.5% and reduced post-exercise blood lactate levels. The study also showed increased muscle oxygenation rates and slower deoxygenation.
A new study finds that e-cigarette users with a limited smoking history experience similar DNA changes to specific cheek cells as smokers. The researchers also found that some smoking-related epigenetic changes remain more stable after giving up smoking, suggesting that e-cigarettes may not be completely safe.
Researchers at Rensselaer Polytechnic Institute have developed a patented process to produce heparin in the lab, offering a consistent and safe supply of the essential medicine. The discovery has the potential to revolutionize the production of heparin, reducing reliance on animal-derived sources and addressing global supply chain issues.
Researchers analyzed molecular data from brain tissue and blood of individuals who committed suicide, identifying risk markers for novel therapeutic targets. The study found alterations in the prefrontal cortex and inhibitory neurotransmitters, highlighting potential new approaches for preventing suicidal behavior.
Tulane University researchers have developed a CRISPR-based platform for diagnosing nontuberculous mycobacteria (NTM) infections, allowing for accurate results in as little as two hours. The blood test can identify over 93% of patients with an NTM infection, enabling rapid treatment plans and reducing the risk of complications.
Researchers found associations between prenatal vitamin and metal exposures and epigenetic aging biomarkers in early life. A one standard deviation increase in essential metals was associated with lower Horvath EAA at birth, while arsenic was linked to greater EAA at birth and in childhood.
Researchers at the University of Virginia Health System are developing a technique to 'paint' tiny nanoparticles on transplanted veins to prevent blockages, potentially sparing patients from repeated surgeries. This approach could significantly reduce the number of vascular reconstructions performed annually in the US.
Researchers at Staffordshire University and the University of Hull studied bloodstain patterns in microgravity, revealing unique challenges for forensic investigators. The study found that amplified surface tension and cohesion cause blood droplets to stick to surfaces, leading to slower spread rates and altered shapes.
A new study has revealed a molecular fingerprint of biological aging, shedding light on why people age differently. The researchers identified 25 metabolites that can reflect biological age, known as the Healthy Aging Metabolic (HAM) Index, which was found to be more accurate than other aging metrics.
A U.S.-Canadian research collaboration identified common blood changes as a risk factor for acute kidney injury (AKI) in over 1 in 5 hospitalized adults. The discovery may lead to new, more effective treatments for AKI and prevent its progression to end-stage renal disease.
Research from UCSF found COVID antigens lingering in blood up to 14 months and tissue samples for over two years after infection. The persistence of these fragments may drive long COVID symptoms and associated risks.
Researchers at XPANCEO and Nobel laureate Konstantin S. Novoselov unveil new properties of rhenium diselenide and rhenium disulfide, enabling novel light-matter interaction. This breakthrough has huge potential for integrated photonics, healthcare and AR applications.
Researchers at Aarhus University have developed a new cell-based assay to measure total cortisol levels accurately, improving diagnosis and treatment of stress-related illnesses and chronic conditions. This method has the potential to reduce misdiagnoses and side effects, enabling more precise treatment.
The new guidelines recognize the aorta as an independent organ, bundling its treatment with other specialties. This holistic approach improves treatment outcomes for patients with aortic rupture and other serious diseases.
A study of routine fecal occult blood testing found a significant decrease in colorectal cancer mortality in Sweden. The association between screening and reduced mortality is expected to be higher due to co-existing testing and delayed diagnoses.
Researchers at the University of Waterloo have developed a rapid blood testing method that can detect fentanyl and other opioids in under three minutes, making it twice as quick as traditional approaches. This new technique has the potential to save lives by quickly identifying overdoses.
Researchers found that pulse oximeters underestimate blood pumping and overestimate resistance, affecting treatment decisions. Direct blood oxygen measurement is crucial for accurate guidance, especially for Black patients already at higher risk.
A new blood test uses the biomarker BD-tau to predict functional outcomes in patients after ischemic stroke. Higher levels of BD-tau are associated with more severe outcomes.
Researchers identify a promising prognostic biomarker for lung cancer using circulating tumor DNA-based minimal residual disease detection. The study found that this method can effectively guide treatment decisions and predict recurrence risk, potentially modifying the lung cancer treatment paradigm.
Researchers from Brigham and Women's Hospital propose innovative solutions to address the global blood crisis, including civilian walking blood banks and intraoperative auto-transfusion. These short-term strategies aim to increase access to blood transfusion in rural settings, where millions of people lack basic medical care.
Researchers developed a test to predict which heart attack patients are likely to experience dysfunction after receiving mechanical pumps. The test measures pulmonary vascular compliance and its adaptability, helping doctors prevent right ventricle failure.
Researchers at Uppsala University have developed a tool that uses standard blood test results to identify individuals at increased risk of having a heart attack within six months. The study analyzed data from 169,053 individuals and identified 90 molecules linked to a first heart attack.
Researchers identified blood proteomic markers associated with hepatocellular carcinoma (HCC) in patients with cirrhosis. The study found a set of biomarkers, including TGF-β driven mechanistic biomarkers and Myostatin and Pyruvate Kinase M2, which may stratify risk for HCC.
Researchers found that injecting a substance to block an artery and combining it with surgery significantly reduced the risk of repeat surgery for patients with subdural hematomas. The study, published at the American Stroke Association's International Stroke Conference, showed a nearly 3-fold reduction in re-operation rates.
A new blood test developed by Indiana University School of Medicine has identified biomarkers that can objectively measure schizophrenia severity and predict future risk. The test enables personalized treatment matching, reducing uncertainty and improving patient outcomes.
Researchers found that positioning stroke patients with large vessel ischemic strokes at 0-degrees resulted in significant improvements in neurological function compared to those with 30-degree head positioning. This approach optimized blood flow through the narrowed artery and improved collateral arteries, leading to better outcomes.
Johns Hopkins researchers have made progress toward developing a blood test to identify disease-associated changes in the brain linked to postpartum depression and other psychiatric disorders. They identified 26 placental mRNAs present in maternal blood only during pregnancy, which reflected changes occurring inside the tissues.
Researchers found that adding blood thinners to clot-busting medications for ischemic strokes did not improve physical function at 90 days post-stroke. The study, MOST, enrolled 514 patients and analyzed the effectiveness of two blood-thinning medications.
Researchers found a four-fold increase in immune response when people alternate arms during two-dose vaccinations. The study showed improved immunity to the original and omicron variants after three weeks and persisted beyond 13 months.
Researchers discovered a new role for Mfsd7c in exporting excessive choline from the brain. The study suggests that targeting this protein could lead to therapeutic interventions for Alzheimer's disease and other neurological disorders.
A study of over 1,700 adult patients found that gastric bypass and sleeve surgeries have few short-term complications and are equivalent in terms of risk. The results suggest that patients and doctors can choose between the two procedures without worrying about short-term surgical risks.
Researchers developed an AI algorithm to monitor patient variables and predict sepsis before symptom onset. The tool resulted in a 17% reduction in mortality rates.
A study found rectal examinations offer no advantages over PSA blood tests for detecting prostate cancer. The research analyzed data from 85,738 participants and concluded digital rectal examination alone or with PSA is not more effective than the PSA test.
A team of researchers from MIT and the Broad Institute developed two types of injectable molecules called 'priming agents' that can boost DNA levels in blood samples, allowing for earlier cancer diagnosis and more sensitive detection of tumor mutations. The approach could also help improve detection of cancer recurrence.
Researchers developed an AI-driven algorithm that accurately predicts death and complications after percutaneous coronary intervention (PCI). The tool uses patient feedback to provide a patient-centered, individualized risk prediction score.
Researchers discuss reductive carboxylation of glutamine as a potential target in acute myeloid leukemia (AML), an aggressive cancer with poor patient outcomes. The approach aims to weaken tumor cell survival mechanisms, potentially leading to novel therapies and improved patient outcomes.
Sezáry syndrome patients face a vicious circle where cancer and treatment weaken the immune system, allowing bacteria like S. aureus to thrive. Eliminating these bacteria may make cancer cells more susceptible to anti-cancer drugs.
Researchers found that small declines in blood lead levels were associated with long-term cardiovascular health improvements, including reductions in systolic blood pressure and markers of hypertrophic cardiomyopathy and heart failure. This study suggests that even small decreases in blood lead levels can have meaningful health outcomes.
The review discusses the optical aspects of QPAT, including mathematical models for light propagation and interaction with biological tissues. The authors outline two approaches to estimating chromophore concentrations from absorbed optical energy density data, highlighting the challenges associated with practical implementation, such ...
Researchers found a decade-long decline in blood lead levels among American Indian adults was correlated with long-term cardiovascular health benefits, including reduced systolic blood pressure. The study suggests that even small decreases in blood lead levels can have meaningful health outcomes.
Research finds that people with higher HIV viral loads have higher recombination rates, enabling the virus to diversify and evade the immune system. This study contributes to a deeper understanding of how recombination drives HIV evolution.
A biorobotic heart with a silicone robotic pump system can mimic the structure and function of a healthy or diseased heart. The device allows surgeons and researchers to demonstrate various interventions while collecting real-time data, bridging gaps between current simulators and animal studies.
Researchers discovered that fruit bats have a genetic system controlling blood sugar levels, allowing them to consume up to twice their body weight in sugary fruit daily. The study's findings may lead to the development of better insulin- or sugar-sensing therapies for people with diabetes.
New research reveals that the age at which individuals are tested for VWD significantly affects their diagnosis, with older patients more likely to be misdiagnosed. The study also found that as people with VWD get older, they respond better to treatment, potentially reducing medication and side effects.
A recent study in Uganda found that asymptomatic individuals with low-level malaria infections had highly variable parasite dynamics and species present. Frequent sampling every other day or daily was sufficient to detect a proportion of infections similar to daily testing, but less frequent tests may miss up to one-third of cases.
A new study found that COVID-19 infection can lead to persistent brain injury markers in the blood even months after recovery from hospitalization. Patients with neurological complications during the acute phase of the illness showed robust biomarker evidence of ongoing neuroglial injury.
A new study from the University of Gothenburg reveals that night owls are more likely to develop artery calcification than early risers. The research, which examined data from over 771 middle-aged participants, suggests that circadian rhythms play a crucial role in cardiovascular disease.
Researchers found rivaroxaban associated with nearly 40 bleeding events per 100 patients over a year, while apixaban had similar bleeding events as warfarin but more major bleeds. Apixaban also showed lower mortality rates compared to the other medications.
Researchers at Johns Hopkins Medicine have identified six protein markers that can predict and manage acute kidney injury (AKI), a condition marked by serious inflammation. The study's findings offer hope for non-invasive assessments of AKI, potentially reducing the need for invasive kidney biopsies.
Researchers at the University of Pittsburgh have developed a novel embryo-like model, heX-Embryoid, which replicates key features of early human development, including blood cell generation. The model has been shown to produce structures similar to blood islands and detect progenitors of red blood cells, platelets, and white blood cells.
A phase III trial has found that personalised treatment for chronic lymphocytic leukaemia (CLL) can improve survival and remission rates. The trial showed that individualising therapy based on regular blood tests significantly improved progression-free and overall survival in patients with previously untreated CLL.
A new study published in the Journal of the American Heart Association found that many couples around the world share high blood pressure. The research analyzed data from over 50,000 couples in four countries and found a strong association between partners' blood pressure status.
The discovery of fossilized male mosquitoes in 30 million-year-old amber suggests that males were also hematophagous, feeding on blood. This finding helps narrow the 'ghost-lineage gap' for mosquitoes and complicates our understanding of the evolution of blood-feeding habits.
Researchers at Temple University Health System report that the BASHIR Endovascular Catheter reduces blockages in lung arteries and correlates with improved right ventricle function, suggesting better survival outcomes. The catheter also shows significantly lower bleeding rates compared to other devices.
Researchers have developed a device that detects glucose and adenosine monophosphate biomarkers in saliva with high sensitivity, enabling easy at-home health monitoring. The electrochemical aptamer-based biosensor is simple, accurate, and stable, making it suitable for use without laboratory equipment.