Articles tagged with Blood
A new study has revealed a molecular fingerprint of biological aging, shedding light on why people age differently. The researchers identified 25 metabolites that can reflect biological age, known as the Healthy Aging Metabolic (HAM) Index, which was found to be more accurate than other aging metrics.
A U.S.-Canadian research collaboration identified common blood changes as a risk factor for acute kidney injury (AKI) in over 1 in 5 hospitalized adults. The discovery may lead to new, more effective treatments for AKI and prevent its progression to end-stage renal disease.
Research from UCSF found COVID antigens lingering in blood up to 14 months and tissue samples for over two years after infection. The persistence of these fragments may drive long COVID symptoms and associated risks.
Researchers at XPANCEO and Nobel laureate Konstantin S. Novoselov unveil new properties of rhenium diselenide and rhenium disulfide, enabling novel light-matter interaction. This breakthrough has huge potential for integrated photonics, healthcare and AR applications.
Researchers at Aarhus University have developed a new cell-based assay to measure total cortisol levels accurately, improving diagnosis and treatment of stress-related illnesses and chronic conditions. This method has the potential to reduce misdiagnoses and side effects, enabling more precise treatment.
The new guidelines recognize the aorta as an independent organ, bundling its treatment with other specialties. This holistic approach improves treatment outcomes for patients with aortic rupture and other serious diseases.
A study of routine fecal occult blood testing found a significant decrease in colorectal cancer mortality in Sweden. The association between screening and reduced mortality is expected to be higher due to co-existing testing and delayed diagnoses.
Researchers at the University of Waterloo have developed a rapid blood testing method that can detect fentanyl and other opioids in under three minutes, making it twice as quick as traditional approaches. This new technique has the potential to save lives by quickly identifying overdoses.
Researchers found that pulse oximeters underestimate blood pumping and overestimate resistance, affecting treatment decisions. Direct blood oxygen measurement is crucial for accurate guidance, especially for Black patients already at higher risk.
A new blood test uses the biomarker BD-tau to predict functional outcomes in patients after ischemic stroke. Higher levels of BD-tau are associated with more severe outcomes.
Researchers from Brigham and Women's Hospital propose innovative solutions to address the global blood crisis, including civilian walking blood banks and intraoperative auto-transfusion. These short-term strategies aim to increase access to blood transfusion in rural settings, where millions of people lack basic medical care.
Researchers developed a test to predict which heart attack patients are likely to experience dysfunction after receiving mechanical pumps. The test measures pulmonary vascular compliance and its adaptability, helping doctors prevent right ventricle failure.
Researchers identify a promising prognostic biomarker for lung cancer using circulating tumor DNA-based minimal residual disease detection. The study found that this method can effectively guide treatment decisions and predict recurrence risk, potentially modifying the lung cancer treatment paradigm.
Researchers at Uppsala University have developed a tool that uses standard blood test results to identify individuals at increased risk of having a heart attack within six months. The study analyzed data from 169,053 individuals and identified 90 molecules linked to a first heart attack.
Researchers found that injecting a substance to block an artery and combining it with surgery significantly reduced the risk of repeat surgery for patients with subdural hematomas. The study, published at the American Stroke Association's International Stroke Conference, showed a nearly 3-fold reduction in re-operation rates.
Researchers identified blood proteomic markers associated with hepatocellular carcinoma (HCC) in patients with cirrhosis. The study found a set of biomarkers, including TGF-β driven mechanistic biomarkers and Myostatin and Pyruvate Kinase M2, which may stratify risk for HCC.
A new blood test developed by Indiana University School of Medicine has identified biomarkers that can objectively measure schizophrenia severity and predict future risk. The test enables personalized treatment matching, reducing uncertainty and improving patient outcomes.
Researchers found that positioning stroke patients with large vessel ischemic strokes at 0-degrees resulted in significant improvements in neurological function compared to those with 30-degree head positioning. This approach optimized blood flow through the narrowed artery and improved collateral arteries, leading to better outcomes.
Johns Hopkins researchers have made progress toward developing a blood test to identify disease-associated changes in the brain linked to postpartum depression and other psychiatric disorders. They identified 26 placental mRNAs present in maternal blood only during pregnancy, which reflected changes occurring inside the tissues.
Researchers found that adding blood thinners to clot-busting medications for ischemic strokes did not improve physical function at 90 days post-stroke. The study, MOST, enrolled 514 patients and analyzed the effectiveness of two blood-thinning medications.
Researchers found a four-fold increase in immune response when people alternate arms during two-dose vaccinations. The study showed improved immunity to the original and omicron variants after three weeks and persisted beyond 13 months.
Researchers discovered a new role for Mfsd7c in exporting excessive choline from the brain. The study suggests that targeting this protein could lead to therapeutic interventions for Alzheimer's disease and other neurological disorders.
A study of over 1,700 adult patients found that gastric bypass and sleeve surgeries have few short-term complications and are equivalent in terms of risk. The results suggest that patients and doctors can choose between the two procedures without worrying about short-term surgical risks.
Researchers developed an AI algorithm to monitor patient variables and predict sepsis before symptom onset. The tool resulted in a 17% reduction in mortality rates.
A study found rectal examinations offer no advantages over PSA blood tests for detecting prostate cancer. The research analyzed data from 85,738 participants and concluded digital rectal examination alone or with PSA is not more effective than the PSA test.
A team of researchers from MIT and the Broad Institute developed two types of injectable molecules called 'priming agents' that can boost DNA levels in blood samples, allowing for earlier cancer diagnosis and more sensitive detection of tumor mutations. The approach could also help improve detection of cancer recurrence.
Researchers developed an AI-driven algorithm that accurately predicts death and complications after percutaneous coronary intervention (PCI). The tool uses patient feedback to provide a patient-centered, individualized risk prediction score.
Researchers discuss reductive carboxylation of glutamine as a potential target in acute myeloid leukemia (AML), an aggressive cancer with poor patient outcomes. The approach aims to weaken tumor cell survival mechanisms, potentially leading to novel therapies and improved patient outcomes.
Sezáry syndrome patients face a vicious circle where cancer and treatment weaken the immune system, allowing bacteria like S. aureus to thrive. Eliminating these bacteria may make cancer cells more susceptible to anti-cancer drugs.
Researchers found that small declines in blood lead levels were associated with long-term cardiovascular health improvements, including reductions in systolic blood pressure and markers of hypertrophic cardiomyopathy and heart failure. This study suggests that even small decreases in blood lead levels can have meaningful health outcomes.
The review discusses the optical aspects of QPAT, including mathematical models for light propagation and interaction with biological tissues. The authors outline two approaches to estimating chromophore concentrations from absorbed optical energy density data, highlighting the challenges associated with practical implementation, such ...
Researchers found a decade-long decline in blood lead levels among American Indian adults was correlated with long-term cardiovascular health benefits, including reduced systolic blood pressure. The study suggests that even small decreases in blood lead levels can have meaningful health outcomes.
Research finds that people with higher HIV viral loads have higher recombination rates, enabling the virus to diversify and evade the immune system. This study contributes to a deeper understanding of how recombination drives HIV evolution.
A biorobotic heart with a silicone robotic pump system can mimic the structure and function of a healthy or diseased heart. The device allows surgeons and researchers to demonstrate various interventions while collecting real-time data, bridging gaps between current simulators and animal studies.
Researchers discovered that fruit bats have a genetic system controlling blood sugar levels, allowing them to consume up to twice their body weight in sugary fruit daily. The study's findings may lead to the development of better insulin- or sugar-sensing therapies for people with diabetes.
New research reveals that the age at which individuals are tested for VWD significantly affects their diagnosis, with older patients more likely to be misdiagnosed. The study also found that as people with VWD get older, they respond better to treatment, potentially reducing medication and side effects.
A recent study in Uganda found that asymptomatic individuals with low-level malaria infections had highly variable parasite dynamics and species present. Frequent sampling every other day or daily was sufficient to detect a proportion of infections similar to daily testing, but less frequent tests may miss up to one-third of cases.
A new study found that COVID-19 infection can lead to persistent brain injury markers in the blood even months after recovery from hospitalization. Patients with neurological complications during the acute phase of the illness showed robust biomarker evidence of ongoing neuroglial injury.
A new study from the University of Gothenburg reveals that night owls are more likely to develop artery calcification than early risers. The research, which examined data from over 771 middle-aged participants, suggests that circadian rhythms play a crucial role in cardiovascular disease.
Researchers found rivaroxaban associated with nearly 40 bleeding events per 100 patients over a year, while apixaban had similar bleeding events as warfarin but more major bleeds. Apixaban also showed lower mortality rates compared to the other medications.
Researchers at Johns Hopkins Medicine have identified six protein markers that can predict and manage acute kidney injury (AKI), a condition marked by serious inflammation. The study's findings offer hope for non-invasive assessments of AKI, potentially reducing the need for invasive kidney biopsies.
Researchers at the University of Pittsburgh have developed a novel embryo-like model, heX-Embryoid, which replicates key features of early human development, including blood cell generation. The model has been shown to produce structures similar to blood islands and detect progenitors of red blood cells, platelets, and white blood cells.
A phase III trial has found that personalised treatment for chronic lymphocytic leukaemia (CLL) can improve survival and remission rates. The trial showed that individualising therapy based on regular blood tests significantly improved progression-free and overall survival in patients with previously untreated CLL.
A new study published in the Journal of the American Heart Association found that many couples around the world share high blood pressure. The research analyzed data from over 50,000 couples in four countries and found a strong association between partners' blood pressure status.
Researchers at Temple University Health System report that the BASHIR Endovascular Catheter reduces blockages in lung arteries and correlates with improved right ventricle function, suggesting better survival outcomes. The catheter also shows significantly lower bleeding rates compared to other devices.
The discovery of fossilized male mosquitoes in 30 million-year-old amber suggests that males were also hematophagous, feeding on blood. This finding helps narrow the 'ghost-lineage gap' for mosquitoes and complicates our understanding of the evolution of blood-feeding habits.
Researchers have developed a device that detects glucose and adenosine monophosphate biomarkers in saliva with high sensitivity, enabling easy at-home health monitoring. The electrochemical aptamer-based biosensor is simple, accurate, and stable, making it suitable for use without laboratory equipment.
A literature review found that prioritizing circulation before the airway in trauma patients with major blood loss leads to improved outcomes, including lower mortality rates. This approach, known as CAB, has gained acceptance over the ABC model and is now being recommended by the American College of Surgeons.
Extracellular vesicles have been found to transport bacterial products into human cells, alerting the immune system and potentially affecting physiology. This discovery explains a key mechanism by which bacteria impact our health, with implications for both infections and normal bodily functions.
Forensic scientists have discovered that the protrusions from bloodstains, known as 'tails', contain valuable information about a blood drop's origin. By analyzing these tails, analysts can reconstruct the impact angle and speed of the drop, helping to determine whether a victim was standing or sitting at the time of injury.
Researchers at Texas A&M University have developed a miniature, injectable glucose biosensor and wearable device that enables user-friendly, minimally-invasive continuous glucose monitoring. The device addresses challenges associated with existing CGMs, including size and skin tone compatibility.
A study of over 2,300 patients found that HIV-1 neutralizing antibody response decreases over time but highly potent broadly neutralizing antibodies remain detectable. This finding suggests a possible permanent vaccine response and is an important step toward developing an effective HIV-1 vaccine.
Scientists at the University of Leicester have made a groundbreaking discovery about how cholesterol in our diet is absorbed into our cells. The research, published in Science, highlights the role of two proteins called Aster B and Aster C in transporting cholesterol from the intestine to the bloodstream.
A three-year intensive treatment strategy to lower systolic blood pressure below 120mmHg significantly reduced cardiovascular events, including heart attack, stroke, and death, compared to standard treatment. The study found that participants in the intensive group experienced fewer major vascular events and deaths over a two-year period.
A phase 4 clinical trial found that apixaban, an anti-clotting medication, reduced the rate of stroke and blood clots in adults with implanted heart devices experiencing short bouts of asymptomatic, irregular heart rhythms. The study suggests that these individuals may benefit from receiving an anticoagulant.
A global study found that apixaban reduced the risk of stroke and blood clotting by 37% in patients with device-detected atrial fibrillation, also known as sub-clinical atrial fibrillation (SCAF). The medication also reduced fatal or disabling stroke by 49%.
A new therapeutic, lepodisiran, has shown promising results in reducing lipoprotein(a) levels to undetectable levels for nearly one year. The study found that the medication is safe and effective in lowering Lp(a) levels by more than 94%.
A new anti-clotting medication, abelacimab, has significantly reduced bleeding among people with atrial fibrillation who are at risk of stroke. The AZALEA-TIMI 71 trial found that abelacimab substantially reduced bleeding compared to the current standard of care use of direct-acting oral anticoagulants.
A four-year blood-pressure intervention significantly reduced the risk of developing dementia among adults with high blood pressure, compared to those who received usual care. The study found that lowering systolic blood pressure to less than 130 mm Hg and diastolic blood pressure to less than 80 mm Hg reduced dementia risk.
A single dose of zilebesiran safely and effectively lowered systolic blood pressure in people with mild-to-moderate high blood pressure for up to six months. The study found significant reductions in daytime and nighttime systolic blood pressure, as well as low rates of adverse events.