Researchers at USask have discovered a new peptide that lowers lipid accumulation in human liver cells, offering new avenues for treating metabolic diseases. The finding is hopeful news as there's a lack of new therapies available for these diseases.
A University of Saskatchewan researcher is building tiny pseudo-organs from stem cells to help diagnose and treat Alzheimer's disease. These 'mini-brains' more accurately reflect a fully-fledged adult human brain, allowing for closer examination of neurological conditions.
The study provides insights into the genetic evolution and migration of chickpeas, offering a roadmap for improving the crop's nutritional value and climate resilience. Chickpeas are a main protein source for hundreds of millions of people worldwide, particularly in South Asia, Africa, and other parts of the world.
Researchers at USask discovered excessive sodium absorption in small airways of CF patients, providing new insights into the disease. The study's findings have the potential to improve life for people with CF who cannot benefit from existing medications.
Researchers at USask have sequenced the tepary bean genome to study its heat stress tolerance and disease resistance. The study aims to combine traits of tepary and common beans to create a more sustainable crop variety.
A new study by USask researchers found that a shorter form of a brain protein, Aβ38, halts damage-causing mechanisms of its longer counterpart, Aβ42. This discovery could help identify people at highest risk for developing Alzheimer's and slow or prevent its onset.
A new University of Saskatchewan study found that stretching is superior to brisk walking for reducing blood pressure in people with high blood pressure or at risk of developing elevated levels. Stretching resulted in bigger reductions in blood pressure across all three types of measurement.
USask researchers found that hydrogen peroxide-based disinfectants can raise airborne levels to 60% of the maximum allowed exposure level. Using soap and water or ventilation methods can mitigate risks, according to expert Tara Kahan.
A USask-led international team has sequenced the genomes of 15 wheat varieties representing breeding programs worldwide, enabling scientists to quickly identify influential genes. The results provide a comprehensive atlas of wheat genome sequences, which will accelerate breeding efficiency and meet future food demands.
A USask physicist is leading a world-first collaboration to develop a compact, precise magnetometer using diamond-based technology. The new device has potential applications in geological prospecting, medicine, and quantum computing.
Researchers at USask are conducting a groundbreaking study to investigate the impact of maternal cannabis use during pregnancy on fetal brain development. They will be testing the hypothesis that chronic exposure to high-THC cannabis leads to increased anxiety and reduced cognition in rat pups.
A USask study of 14 healthy individuals wearing face masks during strenuous workouts found no detrimental effects on performance and minimal impact on blood and muscle oxygenation. The researchers' findings support the safe use of face masks in indoor exercise facilities, making them safer for gym-goers and allowing sports to continue.
A global team of researchers found a record-setting smoke cloud from Australian wildfires that measured 1,000 kilometers across and remained intact for three months. The team's findings provide critical information on the impact of wildfires on the Earth's atmosphere, which is expected to increase due to climate change.
A University of Saskatchewan-led team has developed a mathematical model to identify the most resilient lentil varieties against climate change. The model uses factors like temperature and photoperiod to predict which lines will perform well in new regions, supporting global food security.
VIDO-InterVac has been awarded a grant to determine the effectiveness of several antiviral compounds against COVID-19 using a hamster model. The project aims to develop a safe solution to end the pandemic as quickly as possible.
A group of water scientists from 11 countries warns that the shift to monoculture crops and tree plantations can constrain soil-plant-water systems, leading to reduced ecological resilience. The authors emphasize the importance of biodiversity in maintaining healthy ecosystems.
Research published in Science Advances by a University of Saskatchewan-led team reveals an explosion of ancient life on the ocean floor nearly 540 million years ago. The study found evidence of animals actively engineering their ecosystem, constructing diverse burrows that may have laid the foundation for greater diversity in marine life.
A new genome sequencing technology has been used to decode the full genome of black mustard, providing insights into its genetic variation and traits. The research advances breeding of oilseed mustard crops and provides a foundation for improved breeding of wheat, canola, and lentils.
Researchers propose repurposing agtech labs for diagnostic testing in human pandemics. Sophisticated equipment used for crop and animal breeding can be easily adapted for tracing and detection. The approach aims to relieve pressure on limited health sector testing tools and speed up response measures.
A study by VIDO-InterVac researchers discovered that a Salmonella biofilm protein can cause autoimmune responses and arthritis in animals. Similar amyloid proteins have been associated with neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS.
A new AI-enabled gut-imaging device called SmartCap is being developed by the University of Saskatchewan to diagnose gastrointestinal cancers and bleeding. With its ability to generate location-specific data, SmartCap aims to improve diagnostic accuracy and potentially double cancer survival rates globally.
Researchers are investigating re-purposing of approved drugs to treat COVID-19 patients, evaluating highly promising therapeutics, and gathering information on effective interventions. The projects will help prepare for future outbreaks by analyzing best practices from across Canada.
Researchers at University of Saskatchewan are developing a unique saliva-based test to detect SARS-CoV-2 peptides in saliva, which is expected to be more sensitive, less invasive, and less expensive than current methods. The test aims to detect mild or asymptomatic COVID-19 cases and will be available by March 2021.
A USask-led partnership has been awarded $2.5 million to increase climate change education, training, and public awareness globally. The six-year Monitoring and Evaluation of Climate Change Education project will develop a standard set of quality education indicators and train students and policy makers.
A team of researchers has discovered a way to create a nitrogen-rich fertilizer using human waste, which could increase agriculture yields in developing countries and reduce groundwater contamination. The new method involves recycling nitrogen from urine through a process involving biochar and CO2 priming.
Researchers have discovered that a nodosaur, an armoured dinosaur, primarily ate fern leaves, with 88% of its stomach contents composed of chewed leaf material. The team found evidence of specific fern species, including those that grow in fire-scarred landscapes, suggesting the dinosaur adapted to exploit post-fire vegetation.
Microbeam radiation therapy (MRT) uses high-energy X-ray beams to target tumors while sparing healthy tissue. The research team has identified the optimal energy range and developed a precise measurement detector technique to ensure safety and effectiveness for human treatment.
A University of Saskatchewan research team has discovered that bat cells can persistently infect with MERS coronavirus for months due to adaptations from both the bat and virus. This unique 'super' immune system in bats allows coronaviruses to remain long-term without causing harm, suggesting stresses on bats may contribute to species ...
The University of Saskatchewan's VIDO-InterVac has been awarded $23 million to fast-track COVID-19 vaccine development. The funding will support pre-clinical testing and two phases of clinical trials, with the goal of making a safe and effective vaccine available as early as next spring.
A recent study highlights large gaps in the cannabis genome, with less than 50% accurately mapped and 10-25% unmapped. The research aims to develop a molecular breeding program for cannabis comparable to other crops, with potential applications in human and animal health.
VIDO-InterVac will receive $12 million in federal funding to construct a pilot-scale vaccine manufacturing facility and $11.3 million for continued operational funding, enabling the development of a human vaccine for COVID-19.
A University of Saskatchewan research team has been awarded nearly $1 million to develop animal models and test vaccine candidates for the new coronavirus. The project aims to identify suitable animal models to replicate human disease, with a goal of developing a pan-coronavirus vaccine.
Researchers used a virtual flight simulator to compare the effects of two pesticides on locusts, finding that the newer sulfoxamine pesticide does not impair motion detection ability at low dosages. The study suggests that the pesticide may be safer than current neonicotinoid options for agriculture use.
A University of Saskatchewan study found that endangered Colombian poison frog hybrids originated from natural breeding between two known species, rather than human activity. The research confirms the genetic diversity of the frogs benefits the ecosystem.
A new study by the University of Saskatchewan has found that the likely culprit of the Minamata poisoning is alpha-mercuri-acetaldehyde, a mercury waste product not previously identified. This organic mercury species was discharged directly from the Chisso Corporation's chemical factory and contaminated Minamata Bay.
Researchers found that pregnant women in poor countries with lower access to education and employment are more likely to experience stillbirths. The study mapped global patterns of stillbirth rates and identified 37 countries with high rates, including Nigeria and Pakistan.
The first major literary work developed as an app, The Canterbury Tales features a 45-minute audio performance of the General Prologue, along with digitized original manuscripts. New research reveals previously unknown information about the tales' characters and context.
Researchers have discovered that the Canadian tundra was once home to a vibrant, temperate forest, featuring plants such as birch, alder, and elms. The ancient plant fossil record provides valuable insights into how ecosystems responded to greenhouse climates in the past.
A study by the University of Saskatchewan has discovered that liquid crystal monomers from LCDs are present in nearly half of household dust samples, with 90% of these chemicals showing concerning properties. The findings raise concerns about the potential toxicity of these monomers to humans and the environment.
Research reveals that gentoo penguins adapted to a diet of fish and squid, while chinstrap penguins continued to eat krill exclusively, making them more susceptible to climate change impacts. Human activities since the 1930s have led to significant declines in chinstrap penguin populations.
A study published in PLOS Pathogens found that mild Zika virus infection in fetuses can lead to abnormal brain development and impaired immunity in young animals. The research provides new insights into the potential outcomes of Zika virus infection and could point to new prevention and treatment strategies.
New research at the University of Saskatchewan reveals that neonicotinoid pesticides can cause weight loss and delayed migration in wild birds, threatening their survival. Birds exposed to these insecticides suffered significant negative consequences, including appetite suppression and longer stopover times.
Research finds that older stands of trees protect legacy carbon from burning, while younger stands do not. This shift could change boreal forests from a carbon sink to a source, exacerbating climate change. The study's findings have global implications for future climate scenarios.
A study by the University of Saskatchewan found that medicinal cannabis oil containing CBD and THC can reduce or end seizures in children with severe, drug-resistant epilepsy. The research team tested a dosage regimen that showed significant improvements in quality of life for the children, with some experiencing complete seizure freedom.
Research by an international team including the University of Saskatchewan has found toxic metals in European eels' ovaries, potentially jeopardizing their reproductive success. The metals, including mercury and copper, are concentrated in the eels' bodies during their journey to spawning grounds.
Research led by the University of Saskatchewan found a significant increase in extreme downpours globally over the past 50 years, coinciding with intensifying global warming. The study used thousands of rain records to analyze precipitation extremes, revealing a clear upward trend in torrential rain events across various regions.
Researchers at the University of Saskatchewan found that low-frequency magnetic stimulation improved cognitive and motor function in rodents with concussions. The therapy also protected the brain from future degeneration and restored normal sleep patterns.
A USask-led research team is developing an artificial portable kidney that can be worn by patients with renal failure, reducing hospital visits and healthcare costs. The team aims to create a highly efficient dialysis membrane that mimics the human kidney's filtering properties.
A rapidly expanding invasive species, wild pigs are threatening Canada's environment and agriculture. The species has spread across the country, from British Columbia to Ontario and Quebec, causing significant risks to farming and livestock production.
Research by the University of Saskatchewan found that exposure to inflammation during pregnancy alters brain development, predisposing offspring to psychiatric illness like schizophrenia. Young adult rats exposed to a simulated viral infection displayed abnormal behavior, reduced working memories, and altered fear responses.