Articles tagged with Blood
A new study published in the Journal of the American Heart Association found that Mexican American women are more likely to miss prescribed doses of stroke prevention medications. The study highlights sex-associated disparities in stroke care, particularly among racial and ethnic minorities.
A Baycrest study has found that high blood sugar may impair brain health even in people without diabetes. Researchers analyzed data from 146 healthy adults and found a correlation between high blood sugar levels and lower brain activity.
Researchers found that living in neighborhoods with low food access, contaminated drinking water, and proximity to Superfund sites increases PFAS levels in blood. The study provides evidence for addressing neighborhood-level factors in reducing racial and ethnic environmental health disparities.
Researchers developed a novel lentivirus-based gene therapy strategy in CD34+ hematopoietic progenitor cells, which showed therapeutic levels of expression of the anti-sickling beta globin protein. Cyclosporin improved transduction efficiency and preserved cell viability.
Researchers found that sacubitril-valsartan, a commonly prescribed heart failure medication, can help prevent heart damage related to chemotherapy treatment among high-risk cancer patients. The study highlights the importance of identifying patients at high risk for heart damage and suggests strategies for early intervention.
Research highlights edoxaban's effectiveness in reducing stroke and blood clots for patients after bioprosthetic heart valve replacement. Edoxaban was found to be equally or more effective than warfarin, with a predictable pharmacokinetic profile and reduced burden on patients.
A new AI program, PanEcho, has been developed to interpret echocardiography videos independently, reducing wait times and improving timely medical care. The program demonstrated accuracy in estimating continuous echocardiographic parameters and quantifying left ventricle dimensions and function.
A large-scale clinical trial found that intravenous infusion of exenatide during heart surgeries involving bypass did not significantly reduce the risk of death, stroke, or organ failure. The study included approximately 1,400 adults and a randomized, double-blind, placebo-controlled design.
A clinical trial found that combining two commonly recommended medications into a single pill lowered blood pressure and was safe among Indian adults. The study's results have significant meaning for South Asian adults, including those living in the US.
Research published in European Heart Journal reveals that taking an NSAID with anticoagulant medication increases the risk of internal bleeding. The study found a significant increase in bleeding risks for various organs, including gut, brain, lungs, and bladder.
The international SUMMIT trial found tirzepatide lowered the risk of worsening heart failure events and cardiovascular death in obese adults with preserved ejection fraction. Participants experienced improved health status, physical function, and exercise tolerance compared to placebo.
A recent study found that intensive systolic blood pressure reduction approaches can significantly reduce the risk of major cardiovascular events in adults with Type 2 diabetes. Lowering systolic blood pressure to less than 120mmHg led to a reduced risk of heart attack, stroke, and death from cardiovascular disease.
A recent study published at the American Heart Association's Scientific Sessions 2024 found that blood thinners did not reduce cognitive decline in adults younger than age 65 who have atrial fibrillation (AFib) but no other risk factors for stroke. The trial included over 1,200 participants and followed them for an average of 3.7 years...
Scientists use machine learning-based classifiers to differentiate lung cancer and noncancer based on urinary miRNA ensembles. The study reveals high specificity and sensitivity in detecting early-stage lung cancer, offering new hope for improved patient outcomes.
A study found that monochromatic infrared light combined with physical therapy significantly reduced pain and improved sleep quality in patients with peripheral diabetic neuropathy. The treatment was effective in reducing symptoms and improving functionality for patients with intense pain.
Researchers at the University of British Columbia have developed a groundbreaking coating that mimics natural blood vessels to reduce clotting and bleeding risks. The coating's unique properties prevent clot formation without disrupting normal blood functions, offering a promising alternative to high-risk blood thinners.
The American Heart Association has announced five health technology start-up companies as finalists in its 7th annual Health Tech Competition. The competition aims to drive technological advancements with the potential to transform heart and brain health patient outcomes.
Rice bioengineers create a mathematical model that challenges long-held assumptions about IL-12's behavior in the body, suggesting repeated doses cause immune cells to hoard IL-12 before it reaches the bloodstream. The findings have significant implications for IL-12 therapy design and may lead to more effective dosing regimens.
Researchers found that both methods restored blood circulation in about 30% of patients, with no difference in survival or quality of life. The study's results may impact future guidelines for cardiac arrest treatment.
A study led by WVU epidemiologist Bethany Barone Gibbs found that alternating sitting and standing at work reduces sedentary behavior but has no effect on lowering blood pressure. Prolonged static standing may even have negative effects on cardiovascular health due to a physiological mechanism called the muscle pump.
Researchers have successfully integrated genome sequencing into newborn screening to identify hundreds of rare genetic disorders. This approach allows for earlier diagnosis and treatment, promoting health equity and reducing time to diagnosis.
A new clinical guideline from the American Stroke Association outlines strategies to support brain health and prevent stroke throughout a person's lifespan. The guideline recommends regular health screenings, identifying risk factors, lifestyle interventions, and medications to reduce the risk of a first stroke.
Researchers at USC found a link between per- and polyfluoroalkyl substances (PFAS) and kidney damage, which may be tied to dysregulation of the gut microbiome. The study, published in Science of the Total Environment, suggests that changes in gut bacteria and related metabolites can explain up to 50% of decreased kidney function.
Sweden has surpassed the UNAIDS and WHO targets for the HIV epidemic, with 96% diagnosed, 99% on treatment, and 98% having undetectable virus levels. The country's effective infrastructure and comprehensive data collection have made it possible to reach these ambitious targets.
A new study by Simon Fraser University researchers found that folic acid supplementation may weaken the link between blood-lead levels and autistic-like behaviors in children. The study suggests that adequate folic acid supplementation mitigates the neurotoxic effects of lead, reducing the risk of autism.
Researchers found that community-made videos can effectively encourage Black people to donate blood, with 90% of the target audience stating they would be convinced. The approach leverages emotional engagement and co-design with ethnic minorities to address health inequalities.
A history of COVID-19 can double the risk of heart attack, stroke or death for up to three years after diagnosis. Genetic analysis revealed individuals with non-O blood types were twice as likely to experience cardiovascular events.
A nonselective extracorporeal blood purification device reduced cardiac surgery-associated acute kidney injury in nonemergent patients. The study showed a significant reduction of AKI in the first 7 days after surgery.
A new study found that COVID-19 infection increased the risk of heart attack and stroke for up to three years after infection. The risk was higher among people with A, B or AB blood types compared to type O, according to researchers analyzing data in the UK Biobank.
A new study published in Journal of Biogeography finds that malaria-like blood parasites increase in prevalence with the number of bird species present, highlighting the importance of host diversity. The research also shows that parasites can spread more rapidly when they specialize in closely related or functionally similar bird species.
A non-invasive blood test measuring circulating tumor cells can predict treatment response, disease progression, and overall survival in men with metastatic prostate cancer. Patients with more CTCs had shorter median survival lengths and a greater risk of death.
A study published in Environmental Advances found a significant association between four types of PFAS and poor sleep in young adults. The researchers identified genes involved in the body's natural defenses and a hormone that regulates sleep, shedding light on the underlying mechanisms of PFAS' impact on sleep.
Researchers at the University of Virginia Health System have identified a crucial biological switch that regulates renin production in certain cells, allowing them to control blood pressure. This discovery provides important direction for future research into high blood pressure and cardiovascular disease treatment.
The 2024 guideline provides comprehensive recommendations for assessing cardiovascular disease risk and managing patients taking SGLT2-inhibitors. It also highlights the importance of judicious screening and evidence-based management of cardiovascular conditions before, during, and after noncardiac surgery.
A nationwide cohort study revealed a higher risk of placental problems, premature births, and severe bleeding in subsequent deliveries following uterine artery embolization. Babies born to mothers who underwent UAE also had a higher chance of major birth defects, particularly heart problems.
A recent clinical trial found that an IV iron treatment called ferric carboxymaltose works faster and better than oral iron tablets in treating anaemia during pregnancy. The study showed improved haemoglobin levels and iron correction with the IV treatment, with comparable side effects.
Researchers found that adopting an electronic patient management system for direct oral anticoagulants reduced off-label dosing by 8%, while also decreasing the rate of blood clots and strokes. The online dashboard, used at over 120 hospitals, highlights treatment optimization and improves patient safety.
A new study by University of Illinois Chicago researchers found that high levels of toxic metals in urine predicted faster increases in blood sugar. Individuals with highest arsenic exposure qualified as prediabetic 23 months earlier and diabetic 65 months earlier than those with lowest exposure.
A new preclinical blood test identifies adults most likely to develop severe respiratory conditions, including chronic obstructive pulmonary disease (COPD), by analyzing 32 proteins that accurately predict lung health data. The risk score indicates a high likelihood of hospital care, COPD development, and respiratory disease death.
Aston University researcher has developed a new method of analysing crystals in dehydrated blood samples using polarisation-based image reconstruction technique. The technique showed a 90% accuracy rate for early diagnosis and classification of cancer, making it less traumatic and risky for patients.
Researchers have developed a cost-effective and easily reproducible point-of-care testing device that can accurately measure cortisol levels in the blood. The device uses iridium oxide nanoparticles to improve stability, sensitivity, and selectivity, allowing for commercial use.
Researchers used genetic method Mendelian randomization to show high levels of fasting insulin cause reduction in Lp(a), rather than the other way around. Low Lp(a) is unlikely to be a risk factor for type 2 diabetes, independent of pre-existing hyperinsulinaemia and insulin resistance.
Researchers have found that natural killer cells instinctively recognize and attack the XPO1 protein, which drives cancer growth. By targeting this protein, scientists may be able to activate more killer cells to destroy cancer cells. The study suggests that this approach could lead to personalized cancer treatment with less side effects.
A recent study found that the epigenetic age of a tissue is influenced by the frequency and activity of its stem cells. Stem cells in skin and intestine had a higher rate of division, resulting in a younger epigenetic age compared to those in muscle and blood.
Researchers at Pennington Biomedical are conducting a 12-week study to examine the impact of soy on blood sugar, mood, and energy levels. Participants will receive meals with or without activated soy flour and undergo various tests, including insulin sensitivity and bone density assessments.
Researchers developed an air-powered computer that sets off alarms when certain medical devices fail, preventing blood clots and strokes. The device uses air to issue warnings, reducing costs and improving safety in healthcare settings.
A new study from Murdoch Children's Research Institute has identified changes in certain blood proteins that can predict bronchopulmonary dysplasia (BPD) in preterm babies. By combining these protein changes with gestational age, birth weight, and sex, clinicians can make more accurate predictions of BPD risk within 72 hours of life.
Scientists have developed a new compound, ZTA-261, which selectively binds to the thyroid hormone receptor beta (THRβ) to treat lipid disorders. Mice administered the drug showed decreased lipid levels in the liver and blood with fewer side effects compared to existing compounds.
A University of Michigan-led study found that higher levels of metals in blood and urine are associated with a greater risk for ALS and shorter survival. Occupational exposure to metals was also linked to increased metal levels, emphasizing the need for accounting for environmental factors when evaluating overall exposure risk.
A national multicenter study found that younger women and those with non-malignant diseases had a higher chance of successful pregnancies after allogeneic hematopoietic cell transplantation. The study analyzed data from 2,654 women who underwent transplantation between 2003 and 2018.
A clinical trial found that fish oil supplements slowed neuronal integrity breakdown in older adults with the APOE4 gene variant, a risk factor for Alzheimer's disease. The study showed no benefit for all older adults, but suggested omega-3 fatty acids may be useful for prevention.
Researchers discovered elevated levels of neurofilament light chain protein in Parkinson's disease and dementia with Lewy bodies, suggesting potential early detection methods. The study found different protein patterns between the prodromal stage and established diseases.
A study by Michigan Medicine found that over- or under-dosing anticoagulants can result in serious health conditions, most often occurring after the initial prescription. The researchers evaluated five years of prescribing data and found that nearly 70% of alerts to off-label dosing occurred during a follow-up visit.
A head-to-head comparison of six commercial blood tests found that some are accurate enough to replace spinal taps and brain scans in patients with cognitive impairment. The analysis, led by Suzanne Schindler at Washington University School of Medicine, identified reliable tests for diagnosing Alzheimer's disease.
A recent study published in ESC Heart Failure found that kidney dysfunction can be used as a criterion to stratify patients requiring implantable defibrillators. The research identified two key independent predictors for the risk of sudden cardiac death: left ventricular ejection fraction and estimated glomerular filtration rate.
Researchers studied Alzheimer disease blood biomarkers and found a strong association with incident all-cause dementia risk. Biomarker levels increased with age and were linked to dementia starting in midlife.
Researchers found high diagnostic accuracy for identifying Alzheimer's disease using amyloid probability score 2 blood test and p-tau217 levels. The study suggests blood tests could influence clinical care, warranting further evaluation.
A recent study has identified a blood protein called fibrin as the root cause of developmental delays and brain damage in preterm infants. The researchers found that fibrin interferes with a cell-signaling pathway essential for neuron creation, particularly in the cerebellum.
Researchers found a significant association between the KIT M541L variant and mastocytosis diagnosis in patients with systemic and cutaneous mastocytosis. The variant was identified in 19 individuals, mostly diagnosed with systemic mastocytosis, but without significant differences in symptomatology.
A recent study at the University of Missouri discovered that oxytocin and corticotropin-releasing hormone cause the brainstem to become overactive, leading to hypertension. This finding can help develop targeted drugs to reduce high blood pressure in sleep apnea patients.