Articles tagged with Brain Tissue
A new imaging technique, using second harmonic generation microscopy, allows for the observation of microtubule polarity in living brain tissue. This enables researchers to study neuronal development and repair, as well as neurodegenerative diseases such as Alzheimer's.
A study by Purdue professor Howard Zelaznik and colleagues suggests that stroke victims may retain some motor skills thought to be lost to cerebellar damage. The research found that patients with cerebellum damage struggled with tasks requiring a start-stop nature, but retained ability in continuous rhythmic motions.
Researchers found lower concentrations of amino acid N-acetylaspartate in the right hippocampus of males with bipolar disorder. The study suggests a progressive nature of the disease, with decreasing levels of NAA seen over time.
Research found extensive changes in brain processing of simple motor movements in patients with all three illnesses. The primary motor cortex took over hand motion control in some cases, while others relied on the cerebellum for coordination.
Researchers at Columbia University have found that astrocytes can degrade beta-amyloid proteins, a key component of Alzheimer's plaques, suggesting potential therapeutic targets for the disease. The study suggests activating astrocyte activity may be beneficial in reducing plaque buildup and improving treatment outcomes.
A study on infant rats suggests that high-fat diets and increased production of uncoupling protein 2 (UCP2) may protect the newborn brain from seizure-induced cell injury. The ketogenic high-fat diet is shown to work in human children to prevent or reduce seizures, sparking new research into its potential benefits.
The iScope system provides a platform for researchers to study mouse brain tissue samples and advance understanding of complex traits such as dyslexia and schizophrenia. By enabling real-time access to high-resolution images and genetic data, the iScope facilitates international collaboration and accelerates discoveries in neuroscience.
Key findings from brain bank research highlight the importance of standardized protocols and consideration of quality-related factors. The use of brain banks has led to a better understanding of alcohol-induced brain shrinkage, with potential implications for prevention and reversal of this condition.
A new study confirms the link between exercise and brain changes in aging humans using high-resolution MRI. Fitness slows down age-related decline in brain density, particularly in gray and white matter.
A mild brain injury can make brain cells vulnerable to the immune system's attack, leading to worsening of Alzheimer's and other neurodegenerative diseases. Researchers discovered that drugs targeting specific immune proteins could reduce neural damage in these conditions.
Researchers found that a synthetic antioxidant, AEOL 10150, significantly reduced brain tissue destruction and neurological deficits in mice after stroke. The compound protected potentially salvageable tissue surrounding the damaged cells.
A study by Johns Hopkins Medicine finds that Ecstasy use can cause severe brain dopamine deficits and potentially lead to parkinsonism in humans. The researchers administered MDMA to squirrel monkeys and observed significant neuronal injury.
Researchers found that blocking interleukin-1 can prevent additional brain tissue damage, suggesting a new potential treatment for traumatic brain injury and neurodegenerative diseases. By inhibiting IL-1, macrophage activation is reduced, leading to less inflammation and cell death.
Researchers have designed rough-surfaced, fuzzy polymers to mesh with neurons, improving contact with brain tissue. The polymers' unique surface can fine-tune electrical signal conduction, enabling more efficient neural communication for brain-computer interfaces.
A simple urine test can predict Alzheimer's disease by detecting increased brain oxidative damage in the form of isoprostanes in urine. The test may help doctors diagnose the disease earlier, allowing for slower progression and better treatment response.
A new study confirms that binge drinking can cause neuronal damage in the brain. Damage to the olfactory bulb occurred after just two days of 'binge drinking', while other regions were damaged after four days. The study suggests that alcohol-induced brain damage occurs during intoxication, not withdrawal.
A new technique uses cognitive testing to locate vital brain vessels, allowing for safer embolization procedures. In a study of 14 patients, 12 showed no significant neurological damage after targeted vessel treatment, while 2 required alternative approaches.
A new study has discovered subtle normal appearing brain tissue changes in first-degree relatives of patients with familial and sporadic Multiple Sclerosis (MS). These changes were not detectable using conventional MRI, but a new test called magnetization transfer imaging revealed the damage.
A study found that prolonged abstinence from alcohol can lead to partial reversal of structural brain damage, particularly in the frontal lobes and cerebellum. This suggests that brain function can improve with abstinence, offering hope for recovering alcoholics.
A new study published in the Journal of Neurosurgery found that mild head injuries can cause permanent damage to the brain, with effects not felt for months. The research suggests that repetitive head injuries may be a factor in neurodegenerative diseases like Alzheimer's.
Scientists at UCLA and NIMH detected a spreading wave of gray matter loss in schizophrenic patients, which engulfed the brain over five years, leading to worse symptoms. The study's findings may aid early detection and treatment, as well as inform future medication development.
Researchers have developed a new radiation therapy technique that shows significant improvement over traditional methods in treating brain tumors in infants. The treatment uses high-intensity synchrotron sources to confine x-rays to extremely narrow slices, resulting in reduced damage to surrounding tissue.
Research found that prenatal brains metabolize alcohol differently than adult brains, leading to a rapid accumulation of toxic acetaldehyde. The study suggests that drinking alcoholic beverages during pregnancy can be particularly damaging to the fetus, especially the fetal brain.
Researchers have developed a new way to monitor brain damage in stroke patients, which could increase the number of eligible patients for clot-breaking treatments. The test combines cognitive assessments with MRI scans to identify patients with salvageable brain tissue.
A leading forensic toxicologist suggests that cocaine abuse may be behind some deaths in custody, rather than police brutality. The expert's neurochemical test detects a unique brain signature associated with excited delirium (ED), which can cause sudden death due to cardiac arrest.
A study by Oregon Health Sciences University found that healthy older adults lose brain tissue at a relatively constant rate, not accelerating with age. The research suggests that it's possible to age normally without a rapid decline in brain health.
A protein called osteogenic protein-1 (OP-1) may speed the recovery of stroke patients by rewiring damaged brain cells. The experiment used rats and showed that OP-1 helped them recover lost movement in their limbs quickly, outperforming those in a control group.
Researchers found significant brain tissue loss in individuals with bipolar and unipolar depression, which may help understand the causes of mood disorders. The study's findings provide new information for developing more effective treatments.
The University of Maryland Medical Center now offers a new therapy to prevent stroke disability using the FDA-approved drug Activase. This clot-busting treatment is administered intravenously and can significantly reduce disability risk for patients who receive it within three hours after symptom onset.