Articles tagged with Brain
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Scripps Research scientists created an AI model called MovieNet that processes videos by mirroring brain processes, recognizing visual scenes and distinguishing subtle changes. This breakthrough has the potential to transform fields like medical diagnostics, autonomous driving and more.
Researchers at the University of Tokyo discover that the patterns of spontaneous activity and stimulus-evoked response are similar in lower visual areas of the cerebral cortex but gradually become independent as one moves to higher visual areas. This orthogonal relationship helps explain how sensory perception remains stable despite co...
Researchers will test the hypothesis that environmental manganese exposure is associated with the progression of Parkinson's symptoms and measure neuroinflammation in the brain using MRI scans. The study aims to inform environmental regulations for manganese worldwide and address an environmental justice concern.
A groundbreaking study reveals that macrophages within muscle spindles actively participate in motor control through fast neurotransmitter-mediated mechanisms. These immune cells help fine-tune muscle contractions, providing essential feedback to the nervous system and optimizing energy use during physical activity.
Dr. Seymour Reichlin's centennial celebration highlights his ongoing scientific impact, with recent collaborations yielding new insights into hormone therapies for cognitive enhancement and emotional homeostasis. His work has established neuroendocrinology as a distinct field, bridging neuroscience, endocrinology, and clinical medicine.
Scientists at the University of Texas at Austin and UCLA have created an e-tattoo that can measure brain activity using electroencephalography (EEG). The new method uses a camera to map the individual head's shape digitally, allowing for more precise sensor placement. This innovation could transform brain-computer interfaces, making th...
The American Heart Association warns hunters about the increased risk of heart attack and stroke due to exertion, cold temperatures, and excitement. Hunters should recognize symptoms, take breaks, and have a plan in case of emergencies. Learning Hands-Only-CPR can also save lives.
Researchers have discovered a specific type of body fat linked to abnormal proteins in the brain that are hallmarks of Alzheimer's disease. Higher levels of visceral fat were found to be associated with increased amyloid accumulation and higher PET levels of hallmark pathologic proteins.
Ken Perry, a UTA senior, has been recognized for his research on the connection between high-fat meals and cardiovascular health. He won two awards from the American Physiological Society for his work analyzing data collected from previous studies, which showed a correlation between high-fat consumption and changes in brain blood flow.
Researchers at ISTA and Columbia University developed a technique using adeno-associated viruses (AAVs) to track a frog's nervous system throughout its metamorphosis, shedding light on the neural circuit and behavior changes during this transition. The breakthrough can help usher amphibian neurobiology into a new era.
A team of scientists has pinpointed a critical neural circuit for female sexual rejection, revealing how the brain integrates signals to shape behavior. The ventromedial hypothalamus, specifically progesterone-sensitive neurons in the anterior VMH, play a crucial role in determining whether a female accepts or rejects mating attempts.
Knowing family health history is crucial for reducing heart attack and stroke risk. Experts recommend following Life's Essential 8 - five health behaviors and three health factors to lower genetic risks.
A groundbreaking microscopy method called TRISCO has enabled detailed three-dimensional RNA analysis at cellular resolution in whole intact mouse brains. The new method allows for the study of complex brain anatomy without sectioning, providing a powerful tool for brain research.
A new treatment combination of surgery and embolization for subdural hematomas has been shown to reduce the risk of follow-up surgeries. The procedure, which blocks specific blood vessels, resulted in a 4% recurrence rate compared to 11% without embolization.
Researchers at the University of Arizona Health Sciences have identified a potential new drug, PNA5, that targets cognitive symptoms in Parkinson's disease. The study found that PNA5 dials back inflammation in brain cells, which may prevent further degeneration and alleviate cognitive decline.
Researchers suggest that starting with smaller neural networks and using curriculum learning can improve performance and reduce the need for massive computing resources. This approach could lead to more resource-efficient and less energy-consuming AI systems.
A new study reveals that patients with Parkinson's disease who exhibit rest tremor have more dopamine preserved in the caudate nucleus, a part of the brain important for movement planning and cognition. This challenges traditional understanding of how dopamine loss relates to PD symptoms.
A new study found that individuals with Long Covid experience persistent functional impairment and poor quality of life, leading to significant economic burdens on patients and the economy. The study estimated that the economic cost of Long Covid could reach £20billion annually due to productivity losses and working days off.
Researchers have discovered a remarkably well-preserved fossil bird from the Mesozoic Era, which has been digitally reconstructed to reveal its brain structure. The discovery, named Navaornis hestiae, fills a 70-million-year gap in our understanding of how birds evolved and provides insights into their cognitive abilities.
NeuroMechFly v2 simulates how a fruit fly navigates through its environment while reacting to sights, smells, and obstacles. The model can track moving objects visually or navigate towards an odor source, while avoiding obstacles in its path, enabling researchers to study brain-body coordination and animal intelligence.
Researchers found that non-invasive stereotactic radiosurgery significantly improves tumor control and reduces symptoms such as tinnitus, cranial nerve deterioration, and vestibular dysfunction. Early treatment can prevent tumors from growing over time and spare patients from irreversible problems.
Researchers at Tel Aviv University discovered a variant of TMEM16F protein that enhances the spread of Parkinson's pathology, potentially leading to new treatments. The study found that cells with the mutation secrete more pathological α-synuclein, which can form Lewy bodies and damage brain cells.
A study from Tohoku University reveals that astrocytic manipulation affects the fate of long-term memory, with acidifying astrocytes preventing memories from being remembered and alkalinizing astrocytes preserving them. The findings suggest a parallel process of short-term and long-term memory formation.
A study of socially and economically vulnerable older adults found that African Americans have twice the odds of unrecognized cognitive impairment as White patients. Approximately 82% of Black patients had undiagnosed dementia or mild cognitive impairment, compared to 64% of White patients.
Researchers found that people systematically underestimate their wrist mobility in three out of four hand movements, with an average underestimation of ten degrees. This distortion is believed to protect against injury by preventing overshooting and allowing for small corrections during movement.
A study led by WVU epidemiologist Bethany Barone Gibbs found that alternating sitting and standing at work reduces sedentary behavior but has no effect on lowering blood pressure. Prolonged static standing may even have negative effects on cardiovascular health due to a physiological mechanism called the muscle pump.
A new study led by CAMH shows that a combination of therapies can slow cognitive decline in older adults with conditions increasing the risk of dementia. Participants receiving Cognitive Remediation plus transcranial direct current stimulation experienced slower cognitive decline compared to those receiving a control intervention.
The study found that brain responds rapidly to face-like features, even in ambiguous black-and-white stimuli. Face-likeness affects unconscious processing, and images with high degree of facial likeness are detected faster than those without.
A study found that 4.6% of Nigerian participants with COVID-19 experienced neurologic symptoms, with some still experiencing symptoms two years after their initial episode. Researchers plan to treat these patients using similar techniques used in the US, aiming to alleviate their suffering.
Researchers have unveiled a complex interplay between liver X and thyroid hormone receptors that regulates critical brain functions and protects against neurodegeneration. LXRs play a crucial role in regulating thyroid hormone function in the brain, while both receptors are essential for normal brain development and maintenance.
A recent study published in Neurology has found an association between poor sleep quality and signs of brain aging in late middle age. People with difficulty falling or staying asleep, as well as those who wake up early morning, had more signs of poor brain health
Researchers grew personalized brain organoids from patients with a rare form of autism spectrum disorder to study its impact on brain development. The study revealed that microRNAs play a crucial role in determining the fate of developing brain cells, and an experimental drug may reverse critical cellular signs of autism.
A team of researchers at Penn State College of Medicine has developed a high-resolution 3D atlas of the developing mouse brain, providing a comprehensive view of brain development and structure. The atlas, published in Nature Communications, will help researchers understand neurodevelopmental disorders and analyze large-scale data sets.
A recent study found a potential link between air pollution and cognitive impairment, with fine particulate matter exposure correlating with declined cognitive processing time. Systemic inflammation, driven by an increase in monocytes, may act as a key intermediary linking PM2.5 exposure to impaired cognitive function.
A new study found that transcranial direct current stimulation (tDCS) is a safe and effective treatment for depression when administered at home. Researchers reported significant improvements in depression severity and remission rates compared to a placebo control group.
Researchers at the University of Helsinki studied brain activity of people watching a live dance performance, finding that dance experience affects brain functions associated with movement visualization and social interaction. The study also showed that experts in dance or music displayed stronger synchrony with the performance.
A new study by Penn State researchers reveals that individuals with co-occurring depression and concussion experience more severe symptoms than those with single conditions. The study also found disrupted brain connectivity among participants with both conditions, suggesting a potential need for personalized treatment approaches.
Researchers aim to develop small molecule drugs to target neuroinflammation in the brain, which contributes to cognitive decline. The goal is to slow or even cure Alzheimer's disease, offering a potential game-changer for the therapeutic landscape.
Scientists have identified a novel molecular mechanism underlying brain cell communication, regulating excitatory synapse maturation and contributing to anxiety disorders. The study reveals the TrkC-PTPσ complex governs synaptic protein phosphorylation, leading to abnormal synapse organization and behavioral defects in mice.
Brain cells called OPCs (oligodendrocyte precursor cells) play a crucial role in shaping neural circuitry by pruning unnecessary synapses. This process is essential for the brain's functioning and has been linked to both glioma brain cancer and Alzheimer's disease.
Researchers identify modifiable determinants of cerebral blood flow (CBF) and arterial transit time (ATT) in older adults. A higher BMI was associated with lower CBF and longer ATT, while cardiorespiratory fitness linked to longer ATT in specific brain regions.
Researchers identified AM-101 as a potential new way to enhance radiation therapy for patients with lung cancer that has spread to the brain. The drug's ability to activate GABA(A) receptors increases autophagy in lung cancer cells, making them more sensitive to radiation treatment.
Researchers found that people with schizophrenia who experience auditory hallucinations have impaired brain processes, including a 'broken' corollary discharge and 'noisy' efference copy. This impairment may contribute to the loss of ability to distinguish reality from fantasy.
Researchers at CNIO propose a new treatment for brain metastasis by targeting pro-tumour astrocytes with immunotherapy. They identified TIMP1 as a biomarker to predict when immunotherapy is effective, and a clinical trial is underway to test the therapeutic efficacy of silibinin inhibition.
A new study published in Scientific Reports reveals the importance of foot movement in early infant development and interaction. By using machine and deep learning techniques, researchers found that AI can accurately classify five-second clips of 3D infant movements, with foot movements showing the highest accuracy rates.
Research from Trinity College Dublin found that lower sustained attention in adolescence can predict a larger increase in cigarette and cannabis use by age 23. The study suggests using early biomarkers like sustained attention to identify vulnerable adolescents and guide targeted interventions.
Researchers at Fujita Health University have discovered critical impairments in purine metabolism and ATP recycling in patients with Parkinson's disease. The study highlights the importance of enhancing ATP production to slow disease progression and improve quality of life.
Endomimetics is developing a Bionanomatrix coating to accelerate aneurysm occlusion and minimize thrombus formation in brain aneurysm patients. The coating promotes endothelialization through five synergistic elements, reducing inflammatory responses and platelet adhesion.
A new genetic labeling tool has revealed patterns in brain extracellular matrix (ECM) in mice, including differences in matrix deposition on various neuron types. The tool allows for detection of changes in ECM over time, providing insights into brain development and function.
A study published in Brain Communications found that heatwaves can trigger more seizures in individuals with severe epilepsy. Researchers used intracranial electroencephalography to track brain activity during heatwaves and non-heatwave periods, revealing a significant increase in seizure frequency during hot weather.
A study published in the journal Brain shows that increases in protein levels with new Alzheimer's drugs can explain the slowing of cognitive impairment at least as well as the reduction in amyloid plaques. The researchers found that higher levels of a critical brain protein correlate equally well with cognitive benefits.
New research reveals that human-dog interactions synchronize brain activity, particularly in the frontal and parietal regions. Dogs with autism-associated genetic mutations show reduced synchronization, but treatment with LSD reverses this effect.
Newly developed tools enable selective labeling and manipulation of synapses, advancing understanding of learning, memory, and neurological disorders. The review highlights promising molecular actuators and optogenetic approaches to unravel synaptic function mysteries.
A new library of healthy participants' neuroimaging data has been created to aid in the diagnosis and treatment of traumatic brain injury (TBI). The Normative Neuroimaging Library consists of data from approximately 1900 individuals, providing a comprehensive dataset for clinicians and researchers.
A Trinity scientist has won an ERC Starting Grant to investigate the role of microglia in brain disorders. The project aims to create a detailed map of how these immune cells change during brain damage, disease, or repair, with the goal of developing methods to control and rejuvenate neuropathology.
Researchers investigate how hypernatremia affects microglial responses and evaluate potential therapies. Microglia's response to hyperosmotic stress is found to be associated with NFAT5 expression and NO production.
A recent study demonstrates how real-time haptic feedback can enhance interoceptive awareness, improving mental and physical health. Participants showed improved accuracy in heart rate discrimination tasks after receiving haptic feedback, suggesting a deeper connection between the mind and body.
A recent study suggests that synaptic plasticity is a collective action, where the behavior of one synapse influences others. The researchers found that strong competition among neighboring spines affects their dynamics and influences the direction and extent of plasticity. Understanding how neurons manage synaptic resources may contri...
Researchers mapped 1.65 million cells from 437 aging brains, identifying two distinct paths of cellular change that lead to either Alzheimer's disease or alternative brain aging. These findings offer new insights into the development of Alzheimer's and how it differs from healthy brain aging.
Researchers at Bar-Ilan University used a novel motion simulator to study rodent navigation in dark environments. The study found that rats use airflow cues, combined with their sense of balance, to enhance their self-motion perception. This breakthrough sheds light on the mechanisms behind sensory processing and brain function.