Researchers found that glial cells are activated by interferon gamma in response to pathogen invasion, releasing signals to attract immune cells to fight infection. In the absence of disease or injury, blocked activation led to tissue inflammation, highlighting their role in maintaining healthy intestinal tissue.
A survey of over 50,000 people found that around 11% experience abdominal pain when eating, with symptoms also affecting mental health and daily life. The study highlights the need for meal-related symptoms to be considered in diagnosis and treatment of functional gastrointestinal disorders.
Researchers identified predictive molecular biomarkers for non-response to anti-TNF and anti-integrin therapies in UC. Biomarkers in innate and adaptive immune systems, as well as proteolytic degradation, were found to be predictive of therapy non-response.
A new University of Illinois study found that dairy calves fed with high-protein starter feed had less fat in their body weight gain and more protein devoted to the development of the gastrointestinal system. Producers can improve calf health and productivity by feeding higher-protein starters.
A study of ancient insects has provided new insights into future biofuel production. The firebrats' unique digestive system has revealed the presence of lytic polysaccharide monooxygenases (LPMOs), a new class of enzyme that efficiently digests cellulose. This discovery could lead to the development of sustainable low-carbon fuels.
Researchers studied a 320-million-year-old fossil using X-ray microscopy, revealing evidence of its digestive system for the first time. The discovery sheds light on the early evolutionary history of echinoderms and highlights previously unknown differences between ancient and modern species.
A recent study published in Psychosomatic Medicine found that mental disorders and physical diseases often co-occur in teenagers. The strongest correlations were found between affective disorders (e.g. depression) and diseases of the digestive system, as well as anxiety disorders and arthritis. These associations highlight the need for...
A new surgical method combines laparoscopic-assisted colonoscopy with polypectomy, reducing recovery time and hospital stays. The procedure is less invasive than traditional methods, resulting in shorter discharge times, reduced blood loss, and faster recovery.
Research shows that crows can ingest and excrete infectious prions without being destroyed, posing a risk for the geographic spread of diseases. Crows may play a role in the transmission of prion-caused diseases through their feces.
Researchers found that a protein called hemagglutinin (HA) plays a crucial role in allowing the toxic protein to pass through the intestinal epithelial barrier. The study reveals a species-specific interaction between HA and E-cadherin, which disrupts cell-to-cell adhesion and allows the toxin to enter circulation.
Researchers have discovered a gene that helps clear mucous in the lungs and digestive system of people with cystic fibrosis. By correcting abnormal levels of this gene, they were able to prevent blockages and improve survival rates in mice with CF.
Researchers found that higher vitamin D levels were associated with a significant reduction in total cancer incidence and mortality, as well as specific types of digestive system cancers. Daily supplementation with at least 1500 IU of vitamin D may be required to optimize benefits on cancer risk.
Research by Scott McWilliams at the University of Rhode Island shows that birds' digestive systems adapt to meet changing energy demands during migration. Birds need sufficient protein to build their digestive tract, which can impact habitat management at key stop-over sites.
The UPMC Image Engine Project combines clinical images with medical records to improve patient care. The system allows clinicians to download and view full-size images for diagnosis and treatment, while maintaining patient confidentiality.