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A new reagent makes living brains transparent for deeper, non-invasive imaging

Researchers at Kyushu University develop a new tissue-clearing reagent, SeeDB-Live, enabling repeated, reversible, and real-time imaging of living brains at greater depth and clarity. This breakthrough allows scientists to visualize neural activity in living mice and brain slices, offering new insights into brain dynamics and function.

SourceKyushu University·JournalNature Methods·TypeExperimental study·DateMar 12, 2026
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Oncotarget | Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients

Researchers developed predictive models using serum microRNAs to identify patients at risk of requiring early palliative care. The study used serum samples from 178 patients with various types of cancer and found that miRNA-based models had higher accuracy than clinical models in predicting referral to a palliative care unit.

SourceImpact Journals LLC·JournalOncotarget·TypeObservational study·DateDec 29, 2022

U of T researchers identify how cells move faster through mucus than blood

A study published in Nature Physics reveals that specialized cell movement may explain the progression of cancer and cystic fibrosis. Cells with ruffled edges sense viscosity and adapt to increase their speed, moving faster through mucus than blood. This discovery sheds light on disease mechanisms and potential treatments.

SourceUniversity of Toronto·JournalNature Physics·TypeExperimental study·DateJul 25, 2022