Articles tagged with Heart
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at Columbia University have used Electromechanical Wave Imaging (EWI) to localize cardiac arrhythmias more accurately than 12-lead ECGs alone, providing 3D visualization for easier anatomical location. The technique achieved a correct prediction rate of 96% compared to 71% for ECG.
Dr. Emelia J. Benjamin, a renowned researcher and educator, has been recognized with the Alliance for Academic Internal Medicine Diversity Award for her tireless efforts to promote ethnic, racial, and gender diversity within Boston University School of Medicine and Boston Medical Center.
A study by the American College of Cardiology found that people who took more steps daily, as tracked by their smart watch, had lower blood pressure on average. The research used data from over 638 participants who wore an Apple Watch for about five months.
Researchers at University of California San Diego School of Medicine identified a novel way to treat Danon disease using gene therapy, adding a specially designed gene that restores LAMP2 function. The treatment improved cardiac and liver function in mice with the disease, offering a new approach beyond heart transplants.
A case report published in HeartRhythm Case Reports describes a patient whose e-cigarette caused magnetic reversion in their implantable cardioverter-defibrillator, interrupting its ability to detect heart rhythm problems. The incident highlights the importance of keeping electronic devices away from medical-grade implants.
A study published in JAMA Cardiology found that individuals who maintain intermediate to ideal cardiovascular health for longer periods are 33% less likely to develop hypertension and other diseases. This suggests that promoting healthy behaviors throughout life may be beneficial for reducing the risk of chronic diseases and mortality.
Researchers at Florida State University have discovered new genetic variants that cause heart disease in infants, revealing novel insights into the role of a protein affecting blood pumping force. Understanding these interactions could lead to new treatments for both the specific disease and general heart disease.
A large-scale analysis of electronic health record data found that 60% of patients had controlled blood pressure, but only 12% received new medication when readings were high. Improving medication intensification rates could lead to significant improvements in blood pressure control.
Researchers found that consuming more than half a tablespoon of olive oil per day was associated with a 15% lower risk of cardiovascular disease and a 21% lower risk of coronary heart disease. Replacing butter, margarine, or dairy fat with olive oil also showed significant health benefits.
Researchers used PET myocardial perfusion imaging to quantify myocardial blood flow and flow reserve, successfully detecting cardiac allograft vasculopathy and predicting prognosis. The study found MFR had higher accuracy in predicting overall prognosis for cardiac transplant patients.
Preliminary research suggests that older adults can benefit from light-intensity physical activities such as household chores or casual walking, which can lower the risk of death from any cause. In contrast, sedentary time is associated with a higher risk of dying.
Researchers from King's College London develop a digital twin of the heart using computer models to improve diagnosis and prediction of future heart health. The Digital Twin can also inform daily lifestyle choices and provide early warnings for potential risks.
Preliminary research suggests that improved sleep patterns can lower the risk of heart attacks, strokes, and other cardiovascular diseases. Regular bedtimes and consistent sleep duration can also lead to healthier body weights.
An international team of researchers has identified genes related to cardiorespiratory function during acute periodic breathing, a condition that occurs in most humans at high altitudes. The study found that genetic variants affecting the response to insufficient oxygen impact the coordination between heart and lung functions.
For most people, moderate to vigorous physical activity is beneficial to overall cardiovascular health. However, intense exercise programs like marathons and triathlons can raise the risk of sudden cardiac arrest, atrial fibrillation, or heart attacks, particularly in inactive individuals with known or undiagnosed heart disease.
Research suggests that conventional cardiovascular disease risk factors are not associated with menopause age, but estrogen loss does compromise heart health. Women should be given hormone replacement therapy (HRT) to prevent this harm, according to specialists in a linked editorial.
Researchers identified a unique collection of gut bacteria associated with pulmonary arterial hypertension (PAH), predicting its presence with 83% accuracy. This discovery may lead to new therapies targeting the digestive system and improving PAH diagnosis.
Researchers developed a wirelessly powered, leadless pacemaker that can synchronize both sides of the heart, reducing complications associated with traditional pacemakers. The device has shown impressive clinical outcomes measures and is being further miniaturized for implantable use.
A new study led by pediatric cardiologist Brett Anderson aims to uncover the reasons behind health inequities in poor children who undergo heart surgery. The research will analyze data from 11 hospitals across New York state to identify mechanisms driving disparities in outcomes.
A study by Scripps Research Institute found that resting heart rates vary widely between individuals, with norms differing by up to 70 beats per minute. Despite this variability, rest heart rate remains relatively consistent over time, holding potential for early detection of health changes.
A new analysis from the Study of Women's Health Across the Nation (SWAN) finds that heart disease risk increases significantly as women enter menopause, with arterial stiffness rising by up to 7.5% within a year before and after the last menstrual period.
A clinical trial found that IV drugs can rapidly restore normal heart rhythm in patients with acute atrial fibrillation without sedation or shocks. The study showed that both drug-shock strategies were equally good at restoring normal heart rhythm and getting patients home the same day.
The American Heart Association's 2030 Impact Goals aim to increase healthy life expectancy globally, with targets of 67 years by 2030. Despite positive trends in cardiovascular health, the US faces challenges such as obesity and inadequate physical activity among youth.
A new study published in NEJM compares minimally invasive TAVR to traditional open-heart surgery and finds no statistically significant difference in mortality or disabling stroke rates. The study, involving over 2,000 patients, also shows improvements in disease-specific quality-of-life measures.
Sir Magdi Habib Yacoub has been honored with the 2020 Earl Bakken Scientific Achievement Award for his pioneering work in heart-lung transplantation and cardiothoracic surgery. He has performed over 2,500 heart transplants and 20,000 heart operations, transforming small hospitals into major transplant programs.
A University of Tsukuba study reveals that histamine, a key factor in inflammation, can control the severity of cardiorenal syndrome in mice. Histamine agonist drug prevents further damage in a mouse model of cardiorenal dysfunction, showing protective changes in gene expression.
Patients who undergo open heart surgery can be discharged in 3 days without increased risk of complications, according to a recent study. Enhanced recovery after surgery (ERAS) programs aim to improve patient-centered care and reduce hospital stays by up to 30%.
A recent study suggests that young and middle-aged adults with aortic valve disease may be better off with open heart surgery than TAVR. The research found lower stroke rates and better patient survival with surgical aortic valve replacement compared to TAVR.
A ClinGen panel validated three genes associated with long QT syndrome, disputing nine other genes linked to the condition. The study highlights the need for critical evaluation of gene-disease associations to prevent patient harm.
Researchers propose using prolonged breath-holding to target radiotherapy in patients with cardiac arrhythmias. The technique involves mechanical hyperventilation and is well-tolerated by patients with angina.
A new study from the Smidt Heart Institute found that women's blood vessels age faster and are more susceptible to high blood pressure earlier in life. The research highlights sex differences in cardiovascular physiology and disease, emphasizing the need for tailored treatment approaches.
A study of over 23,000 adult childhood cancer survivors found a significant decline in serious heart conditions and coronary artery disease risk since the 1970s. The decline is largely attributed to efforts to reduce toxic effects of treatment, including radiotherapy.
Scientists at Iowa State University restored much of the cardiac function in middle-aged flies, which experience many of the same heart maladies as middle-aged humans. By boosting a key genetic pathway called mTORC2, researchers almost fully restored heart function, showing promise for treating human heart disease.
Researchers found that relaxin upregulates sodium channels, improving electrical signaling in the heart, and reverses age-related reductions in cell adhesion molecules. This discovery may lead to new therapeutic potential for cardiovascular disease treatment.
Fulminant myocarditis, a rare condition causing severe inflammation of the heart, is increasingly being recognized due to advancements in technology. Early recognition, circulatory support, and maintenance of end-organ function can lead to favorable outcomes for patients with fulminant myocarditis.
A new study published in Annals of Thoracic Surgery found that many 'high-risk' donor hearts can be transplanted with similar survival rates as 'low-risk' donor hearts. The researchers, led by Dr. David Morales, used a risk-based matching system to match donors with recipients and found that the results were promising.
A cohort study found that preoperative N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations were independently associated with vascular death or myocardial injury at 30 days after surgery. Preoperative NT-proBNP thresholds improved discrimination and risk stratification for patients undergoing noncardiac surgery.
Patients transplanted with hepatitis C-positive donor hearts had comparable outcomes after one year compared to those receiving hearts from disease-free donors. The study suggests using such hearts can expand the donor pool, reduce wait times and improve patient survival rates.
Scientists reveal key details about how sodium channels power heartbeats and respond to heart rhythm drugs. The study provides a blueprint for understanding cardiac sodium channels, revealing characteristics that distinguish them from other ion channels.
A new study published in the Journal of the American Heart Association finds that heavy drinking can cause subclinical heart damage, increasing levels of blood biomarkers associated with inflammation and cardiac wall stretch. Heavy drinkers are more likely to experience cardiovascular disease than non-problem drinkers.
The American Heart Association suggests focusing on an overall heart-healthy dietary pattern that replaces saturated fats with polyunsaturated fats to maintain healthy LDL cholesterol levels. A nutrient-rich diet emphasizing fruits, vegetables, whole grains, and lean protein sources can help reduce the risk of heart disease.
Researchers have developed biologic pacemaker-like cells using stem cells from fat, offering an alternative treatment for conduction system disorders and cardiac repair after a heart attack. The new cell type can adapt to the body and respond to physiological changes, eliminating the need for regular maintenance by a physician.
A team of researchers has identified the ADAMTS19 gene as a key player in aortic valve disease, a common congenital condition affecting two percent of the population. The study provides new insights into the molecular mechanisms behind the disease and could lead to more effective treatments.
Research shows air pollution harms hearts in humans and marine species through similar mechanisms, with PM2.5 being a major contributor to increased risk of coronary heart disease and stroke. The study highlights the importance of reducing air pollution to protect human health.
The European Society of Cardiology reports that middle-income countries in Europe are disproportionately affected by cardiovascular disease, with higher mortality rates and more years lost due to CVD. The statistics highlight the need for targeted prevention policies and improved access to modern healthcare facilities.
Geriatric conditions like frailty and cognitive impairments can worsen in cardiac intensive care units, even with excellent heart care. Early mobilization and addressing polypharmacy may improve patient outcomes.
A study of over 4,700 participants found a strong link between elevated sCD14 levels and increased risk of dementia, as well as brain atrophy and decline in executive functions. The researchers hope that sCD14 could serve as a useful biomarker for assessing cognitive decline and dementia risk.
A $1 million international study aims to develop a new therapeutic treatment for people who have suffered heart attacks with extensive cardiac damage. The project, led by UniSA Professor Janna Morrison, explores whether changing the expression of a specific molecule can repair cardiac damage.
A study presented at EuroEcho 2019 found that bariatric surgery significantly improved subclinical heart function, reversing abnormal heart structure and function in obese individuals. The surgery also led to improvements in type 2 diabetes, hypertension, and dyslipidaemia, resulting in a lower risk of cardiovascular disease.
Research presented at EuroEcho 2019 found that common heart drugs may reduce cardiotoxicity in cancer patients, particularly those with breast or haematological cancer. The study suggests these medications should be considered as part of routine care for this patient group.
Changes in heart rate due to low oxygen conditions during pregnancy may predict future heart health, according to research published in the Journal of Physiology. The study used sheep models to examine the impact of chronic hypoxia on fetal heart development and identified potential markers for long-term heart disease risk.
A recent study in Nature sheds new light on heart treatment controversy by showing that stem cell therapy triggers an acute inflammatory response to enhance mechanical properties of injured areas. Injecting living or dead stem cells into the heart's infarct region provides a modest benefit to heart function after a heart attack.
A recent study published in Pediatric Research suggests that early use of breast milk could play a vital role in preventing heart disease in prematurely born infants. The study found that exclusively human milk-fed preterm-born adults had smaller heart chambers and relatively lower blood pressure compared to those who were formula fed.
A new gene therapy aims to 'switch off' genes that promote cardiovascular disease by reducing fatty material buildup in arteries. The treatment, developed at the University of Sheffield, has the potential to slow or stop the progression of heart disease.
Researchers at the University of Birmingham are exploring how mast cells play a role in DVT, a condition that affects tens of thousands of people in the UK each year. By studying mast cells in mice and humans, they hope to develop new medicines that can reduce the risk of bleeding while preventing the condition.
Studies on mice suggest that a neuropeptide αCGRP has beneficial effects on the heart in patients with high blood pressure. Physical activity increases αCGRP levels, which help prevent pathological heart remodeling and cardiac dysfunction. However, long-term use of αCGRP blockers may be hazardous for these patients.
Researchers from Stanford University successfully recorded a blue whale's heart rate for the first time using an electronic sensor attached to the whale's flipper. The data suggests that the whale's heart is operating at its limit, which may explain why blue whales have never evolved to be bigger.
Researchers have identified a decrease in heart transplant survival rates following the implementation of a new donor allocation system in the US. The study found that patients receiving hearts are sicker than in previous systems, leading to an increase in post-transplant mortality.
Leslie Gonzalez, a Texas Heart Institute perfusion student, has been awarded the prestigious Perfusion Without Borders scholarship. She will travel with The Novick Cardiac Alliance to Medellin, Colombia in February 2020, gaining experience on global perfusion practices and preparing for lifelong involvement in mission work.
Emelia J. Benjamin, a renowned researcher and cardiologist, has received two prestigious awards from the American Heart Association for her significant contributions to clinical cardiology and her dedication to mentoring young investigators. She is recognized for over 600 publications and substantial NIH grant support.