Researchers developed a microchip to identify and separate baby mouse heart cells, allowing for the study of their physico-mechanical properties. The findings could provide insights into developing materials that repair heart tissue, with potential applications in cardiac patches, scaffolds, and hydrogels.
Researchers found that limiting fat release from fat cells during heart failure can reduce inflammation and improve cardiac function. In a study, mice treated with a drug blocking fat release showed better outcomes than control groups.
Research from the Smidt Heart Institute found that women have a lower normal blood pressure range compared to men, with systolic pressures above 110mmHg associated with increased risk of cardiovascular disease. The study's authors recommend reassessing blood pressure guidelines to account for sex differences.
The Texas Heart Institute has developed a breakthrough ex vivo benchtop system for evaluating the effects of ablation systems on excised tissues, shedding light on the need for esophageal temperature monitoring during HPSD ablation. The study highlights the importance of safety measures in clinical settings and paves the way for furthe...
A recent study found that drinking one or more cups of caffeinated coffee per day is associated with a decreased long-term heart failure risk. The analysis revealed a significant decrease in heart failure risk over time, ranging from 5-12% per cup per day of coffee consumption.
A new research program, led by health coaches at primary care clinics, has shown that lifestyle interventions can significantly improve heart disease risk factors. Participants experienced lower blood sugar levels, increased good cholesterol, and improved overall cardiometabolic risk scores.
Research from the Smidt Heart Institute found women are more likely to experience sudden death during nighttime hours, with a higher prevalence of lung disease and asthma. Prescribing physicians may want to be cautious when recommending brain-affecting medications to high-risk patients, especially women.
Researchers at Mayo Clinic have developed an AI-powered mobile EKG device that can rapidly and accurately determine a patient's QTc, identifying those at risk of sudden cardiac death from congenital long QT syndrome or drug-induced QT prolongation. The device achieved high sensitivity and specificity in detecting clinically meaningful ...
A study at Boston Children's Hospital found that a multidisciplinary ERAS program reduced opioid use, improved pain control, and expedited recovery for select congenital heart surgery patients. The program implemented strategies like early extubation, blood conservation, and smaller surgical incisions to enhance patient outcomes.
A recent study found a 53% decrease in adult cardiac surgery volume nationwide, with a 65% reduction in elective cases. The pandemic also led to an unexplained increase in deaths after coronary artery bypass grafting, with significant declines in case volume and patient outcomes.
Four leading cardiovascular organizations call for structural actions to reduce air pollutants' harmful exposure, highlighting healthcare providers' crucial role in preventing illnesses. The statement emphasizes the importance of integrating air quality into disease management approaches and educating the public on clean air's benefits.
Stroke survivors who completed a cardiac rehabilitation program focused on aerobic exercise improved their ability to transition from sitting to standing and walked further during a six-minute walking test. The program also showed improvements in leg strength and reduced fall risk.
Researchers at UBCO's Heart Valve Performance Lab have developed a novel bileaflet mechanical heart valve that functions like the real thing, improving blood flow and preventing clots. The design incorporates a slight twist to mitigate clotting risk and enhances overall performance.
A new report from Boston University School of Medicine identifies key research priorities for detecting undiagnosed AF, including developing evidence-based screening strategies and investigating diverse patient subgroups. The study aims to improve diagnosis, management, and prognosis of patients with undiagnosed AF.
The new scientific statement emphasizes the importance of mental health screening for people with or at risk for cardiovascular disease. Regular psychological therapy and mind-body programs can lead to better cardiovascular health, while negative psychological factors are associated with increased risk of heart disease.
A new study funded by the British Heart Foundation measures how sedentary behaviour affects health, particularly heart and circulatory conditions. Researchers analyzed data from 72,000 participants to understand the relationship between physical inactivity, sitting time, and sleep quality on health outcomes.
A new study found that people with abdominal aortic calcification (AAC) have a two to four times higher risk of future cardiovascular events. The more extensive the calcium buildup, the greater the risk.
Scientists at Temple University Health System have identified Kruppel-like factor 5 as a key protein driving both oxidative stress and toxic lipid accumulation in the heart. This discovery opens up new avenues for treating various types of cardiac disease, including diabetes and heart attack.
Researchers found that approximately half of AD cases are mild, while one-fifth are severe. Early intervention in the mild stage is crucial to slow decline and prevent progression.
A study of nearly 108,000 people found that moderate alcohol consumption is associated with a 16% increased risk of atrial fibrillation over 14 years. Regular drinking of even one small alcoholic drink per day may increase the risk, suggesting that low doses of alcohol can trigger atrial fibrillation.
A new study led by Katharine McBride explores the perspectives of 28 Aboriginal women from five different communities across central and southern Australia, identifying 10 attributes that either keep or put their heart at risk. These include identity as an Aboriginal woman, healthy body and life, connectedness within family and communi...
Researchers at NTNU have used CRISPR to strengthen muscle cells and replicate positive exercise effects in heart-diseased rats. This gene therapy approach holds promise for treating heart disease without the need for daily medication.
A team of researchers at the University of South Florida has discovered that Sesn2 protein, which protects the heart from stress, diminishes in levels over time, weakening the heart and increasing the risk of heart attack. This finding holds promise for developing new therapeutic treatments to maintain healthy cardiac function.
The American Heart Association recommends using existing data in electronic health records to adjust health targets and provide better preventive care. Improving the nation's cardiovascular health requires reinforcing prevention efforts and leveraging expertise from multidisciplinary healthcare professionals.
Researchers analyzed data on over 45,000 patients hospitalized for their first heart attack between 2002-2016. The study found that women were older and faced more risk factors than men, which put them at a higher risk of developing heart failure after a heart attack. Women also had lower rates of prescribed medications and revasculari...
A study published by the American Heart Association found that older women who spend more waking hours in sedentary behaviors have an increased risk of heart failure serious enough to require hospitalization. Breaking free from prolonged sitting or lying down can help prevent this serious condition.
A systematic review and meta-analysis of PubMed, Embase, and the Cochrane Library reveals that patients with masked hypertension (MH) may have a similar risk of target organ damage as those with sustained hypertension (SH). This suggests that clinicians should consider target organ damage when managing MH.
Research presented at American Heart Association Scientific Sessions 2020 found that Black and Hispanic patients are more likely to be hospitalized with COVID-19 than white patients. Nonwhite men with cardiovascular disease or risk factors also face a higher risk of death from COVID-19.
The American Heart Association's COVID-19 Cardiovascular Disease Registry found significant racial and ethnic differences in treatment and outcomes for patients hospitalized with COVID-19. Hispanic patients were more likely to have lower health insurance, while Black patients had higher rates of obesity and required more ventilator sup...
Researchers found that high-risk patients recovering from cardiac surgery who wore a continuous cardiac monitor had a 10-fold higher incidence of atrial fibrillation than those with usual care. This suggests that post-operative atrial fibrillation persists even after hospitalization, requiring prompt treatment and surveillance.
Adults with healthy sleep patterns had a 42% lower risk of heart failure compared to those with unhealthy sleep patterns, according to the study. The researchers analyzed data from 408,802 UK Biobank participants and found that healthier sleep habits were independently associated with reduced risk of heart failure.
Researchers found that people with Type 2 diabetes still have a 21% higher risk for cardiovascular disease and 31% higher risk for heart failure hospitalization. Optimizing five key cardiovascular risk factors can help reduce this impact, according to the American Heart Association.
The ALPHEUS trial found no significant difference in periprocedural heart attack and complications between ticagrelor and clopidogrel in patients undergoing elective PCI. The study suggests that ticagrelor should be reserved for acute coronary syndrome cases, not those with stable heart conditions.
Researchers found that rivaroxaban is comparable to warfarin in preventing events in patients with bioprosthetic mitral valves and atrial fibrillation. Rivaroxaban was also shown to be superior to warfarin for a subgroup of patients with recent mitral valve replacement.
Brigham researchers present findings on the effectiveness of lipid-lowering therapies in reducing cardiovascular events and deaths in both younger and older patients. Additionally, a study reveals that over 80% of heart failure patients are eligible for recently FDA-approved SGLT2 inhibitor therapy.
A recent study published in the American Heart Association's Scientific Sessions found that fish oil and vitamin D supplements did not increase or decrease the risk of developing atrial fibrillation. The trial involved 25,119 adults aged 50 and older and followed them for five years. No significant differences were found between those ...
The award recognizes Dr. Kamel's research on atrial dysfunction and stroke prevention, as well as Dr. Yeh's work in clinical interventional cardiology and cardiovascular health care policy. Their contributions have substantially advanced our understanding of cardiovascular disease and outcomes.
A study of patients with acute heart failure found that intravenous iron replacement reduced hospital readmissions by 26% after just one or two injections. Iron deficiency is a common complication, and correcting it may be an effective strategy for preventing recurrent hospitalizations.
Researchers from EPFL have successfully produced a mouse heart organoid in its early embryonic stages using mouse embryonic stem cells. The study mimics the early stages of heart development in the embryo, preserving crucial interactions necessary for embryonic organogenesis.
Recent studies have revealed that cardiovascular adverse events, such as heart failures and arrhythmias, are common in cancer patients treated with CDK 4/6 inhibitors. These agents have significantly improved survival rates for breast cancer patients but come with a risk of cardiac damage.
A recent study found that Black and non-white heart patients experience significant disparities in care and outcomes compared to their white counterparts. These disparities include lower rates of early treatment methods, longer hospital stays, and higher death rates.
Research finds that many transgender people who receive hormone therapy already have unaddressed heart disease risk factors, including high blood pressure and high cholesterol. The study highlights the need for improved access to healthcare and cardiovascular screening for this population.
Two studies presented at the American Heart Association's Scientific Sessions 2020 found that marijuana use is associated with a higher risk of stroke and post-procedure bleeding after PCI. However, marijuana smokers also experienced a decreased risk of acute kidney injury compared to non-users.
A study of over 11,000 middle-aged male African American veterans found that higher fitness levels reduced the risk of developing atrial fibrillation by 30-50%. The research suggests engaging in physical activity can be an effective preventive measure for cardiovascular disease.
A recent study published at the American Heart Association's Scientific Sessions 2020 found that U.S.-born Black women have a higher risk of developing preeclampsia compared to Black women who immigrated to the country. The study analyzed data from nearly 4,000 Black women in Boston and found that foreign-born Black women had a 26% low...
Researchers found a significant association between ozone levels and out-of-hospital cardiac arrest, with a 1% increased risk for every 12 parts per billion increase in ozone. The study also showed that the relationship was present even at concentrations below the EPA air quality standard.
A study found that consuming chili pepper was associated with reduced risk of cardiovascular disease and cancer mortality, including a 26% relative reduction in cardiovascular mortality. Researchers analyzed data from over 570,000 individuals and found significant reductions in all-cause, cardiovascular, and cancer mortality rates.
A study of hospitalized COVID-19 patients with atrial fibrillation/flutter found a significantly higher risk of death and ICU mortality. However, meta-analyses examining the effect of renin-angiotensin-aldosterone system inhibitors on COVID-19 outcomes showed no increased risk of contracting COVID-19 or dying from the illness.
A 12-week standing intervention program significantly reduced sitting time and increased standing time among overweight, sedentary Latinas. The program, tailored to cultural and family-oriented aspects of Latino communities, resulted in an average reduction of 71 minutes daily sitting and an increase of nearly 50 minutes per day standing.
Dr. Ann Marie Schmidt has made critical contributions to understanding the connections between heart disease and diabetes through her discovery of the RAGE receptor. Her work aims to develop targeted treatments for obesity and its complications, with the potential to impact hundreds of millions of lives worldwide.
Dr. Michelle A. Albert is recognized for her groundbreaking research on cardiovascular population research, addressing social determinants of health and health disparities in vulnerable populations. Her work aims to improve cardiovascular health and reduce health inequities globally.
Dr. Nanette K. Wenger is being recognized for her long-term record of successful teaching and mentoring of the next generation of faculty researchers, educators, and healthcare professionals. Her work has significantly improved patient outcomes, particularly in women's heart health.
Researchers have developed AI algorithms to decipher waveform bio signals from the heart and brain, identifying individuals at risk for cardiovascular death. By analyzing these signals during sleep, they can detect hidden signatures indicating homeostatic imbalance or early onset of potentially fatal diseases.
A UConn researcher has identified a suite of genes and regulatory elements critical to normal heart development using genome science technology. The study found over 100,000 regulatory sequences active during human heart development, including more than 13,000 that had never been annotated as active before.
A collaborative team developed an organs-on-a-chip system to monitor heart toxicity from breast cancer drugs. The dual-organ system closely mimics bodily tissues and provides evidence that the interplay between the heart and breast cancer tissues influences cell function and disease progression.
A new study from the University of Copenhagen reveals that people doing hard physical work have a 55-per cent higher risk of developing dementia. Despite previous findings suggesting physical activity reduces dementia risk, this study highlights the importance of 'good' form of physical activity.
Researchers report a promising emerging treatment that combines medications with temporary use of an artificial heart pump to reverse structural damage in the heart. In a multicenter study, 40 advanced heart failure patients were treated with this protocol, resulting in high rates of LVAD removal and improved cardiovascular health.
A study published in Radiology: Cardiothoracic Imaging demonstrates the safety of performing MRI exams in patients with non-MR compatible cardiac devices, including those who are pacemaker-dependent or have abandoned leads. The results showed no adverse events and improved diagnosis and treatment plans for patients.
A new imaging technique has been developed that allows scientists to study the tiny details of a whole animal heart in 3D. This technique may lead to new insights into congenital heart disease and improve survival rates for people born with heart defects. The study reveals structural differences between healthy and defective heart cell...
A new research letter found that clinicians gave more patients temporary mechanical pumps under the new policy, moving them up the transplant list. This could lead to a higher likelihood of prioritizing male patients over females.