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New research finds signal of decreased early post transplant survival in new heart transplant system

Researchers have identified a decrease in heart transplant survival rates following the implementation of a new donor allocation system in the US. The study found that patients receiving hearts are sicker than in previous systems, leading to an increase in post-transplant mortality.

SourceUniversity of Minnesota Medical School·JournalThe Journal of Heart and Lung Transplantation·DateNov 21, 2019

Improving the odds for patients with heart pumps

A new Yale study found a clear association between neurohormonal blockade therapy and increased survival and quality of life for patients with left ventricular assist devices. The study, which analyzed over 12,000 patients, showed a 56% survival rate for those taking NHB therapy compared to 43.9% for those not on the medications.

SourceYale University·JournalJAMA Cardiology·DateNov 19, 2019

Research award for project on heart transplantation

A recent study found that mitochondrial damage-associated molecular patterns (mtDAMPs) are released by DCD hearts following warm ischemia, correlating with subsequent contractile recovery. The research team aims to investigate the role of mtDAMPs in inflammatory responses and recovery of contractile function in cardiac grafts.

Artificial intelligence tool predicts life expectancy in heart failure patients

Researchers developed an AI algorithm based on electronic health records data that accurately predicted life expectancy for heart failure patients, achieving an 88% success rate. The model identified eight readily available variables to determine low- and high-risk of death, providing valuable insight for informed medical decisions.

SourceUniversity of California - San Diego·JournalEuropean Journal of Heart Failure·DateNov 13, 2019

The American Heart Association and the American College of Cardiology publish new joint 2019 Clinical Performance and Quality Measures for Adults with High Blood Pressure

The new 2019 Clinical Performance and Quality Measures for Adults with High Blood Pressure aim to accelerate translation of scientific evidence into clinical practice. The measures evaluate patient care in accordance with the 2017 Hypertension Clinical Practice Guidelines, including timeliness, safety, effectiveness, efficiency, equity...

Teaching preschool caregivers healthy behaviors may promote healthier habits in high-risk groups

A study in a multi-ethnic community found that teaching young adults healthy behaviors and showing them ultrasound images of plaque in their arteries improved their cardiovascular health. The FAMILIA Project showed significant benefits for caregivers who strictly adhered to simple education plans, reducing risk factors for heart disease.

Loosen up!

A study published in the Journal of Applied Physiology found that exercise can reduce artery stiffness associated with heart failure. Regardless of intensity level or duration, any type of physical activity was beneficial for heart health compared to no exercise at all.

SourceUniversity of Missouri-Columbia·JournalJournal of Applied Physiology·DateOct 22, 2019

Researchers discover how left-right information is integrated to correct organ positioning

Scientists from CSIC-UMH have discovered a molecular mechanism that ensures the right equilibrium needed in left-right signaling cascade during development, leading to correct heart positioning. This mechanism involves a transient wave of small molecules called microRNAs that travel along the left-hand side of the embryo.

SourceSpanish National Research Council (CSIC)·JournalDevelopmental Cell·DateOct 17, 2019

New findings enable more heart donations

A new study published in The Journal of Thoracic and Cardiovascular Surgery found that hearts from donors with acute stress-induced cardiomyopathy can be safely transplanted without affecting recipient outcomes. This breakthrough could lead to a significant increase in the supply of donor hearts, estimated at 20-30%.

SourceUniversity of Gothenburg·JournalJournal of Thoracic and Cardiovascular Surgery·DateSep 26, 2019

Bioengineers explore cardiac tissue remodeling after aortic valve replacement procedures

Researchers create biomaterial-based models of heart tissues to understand the impact of aortic valve replacement procedures on cardiac tissue remodeling. The study reveals key proteins associated with myofibroblast deactivation and offers potential for developing innovative therapies for fibrotic diseases of the heart.

SourceUniversity of Colorado at Boulder·JournalScience Translational Medicine·DateSep 11, 2019