Add BrightSurf on Google Email

Predictive value of resting pd/pa for fractional flow reserve assessed with monorail pressure microcatheter in real-world practice

Resting Pd/Pa showed poor agreement with hyper-emic FFR, but specific thresholds (0.96 or greater for normal FFR and 0.82 or less for abnormal FFR) provided excellent sensitivity and specificity. These findings have implications for real-world practice in assessing coronary artery disease.

SourceCardiovascular Innovations and Applications·JournalCardiovascular Innovations and Applications·DateAug 15, 2019

Damaged hearts rewired with nanotube fibers

Researchers at Texas Heart Institute and Rice University have developed biocompatible nanotube fibers that can bridge damaged heart tissues and deliver electrical signals to restore heart function. The fibers were shown to be effective in restoring conduction in preclinical models, even without the presence of a pacemaker.

How HIV infection may contribute to wide-ranging metabolic conditions

A study published in PLOS Pathogens found that HIV-infected cells release a viral protein called Nef, impairing cholesterol metabolism and triggering inflammation in uninfected bystander cells. This impairment causes the formation of excessive lipid rafts and triggers inflammation, potentially contributing to various co-morbidities ass...

SourcePLOS·JournalPLOS Pathogens·DateJul 25, 2019

Study finds key metabolic changes in patients with chemotherapy-associated cardiotoxicity

Researchers at Beth Israel Deaconess Medical Center found that metabolites associated with energy powerhouse mitochondria changed differently in patients who developed heart dysfunction compared to those who did not. Citric acid and aconitic acid levels differentiated the two groups of patients.

SourceBeth Israel Deaconess Medical Center·JournalJournal of Cardiovascular Translational Research·DateJul 18, 2019

CNIC scientists identify an essential protein for correct heart contraction and survival

A team of CNIC scientists identified SRSF3 as crucial for proper heart function and found that its loss leads to reduced expression of genes involved in contraction. Further research revealed that SRSF3 controls the alternative processing of mTOR, a major regulator of cell metabolism, which is essential for heart health.

Researchers developing new treatment that could protect people with cardiovascular disease

Researchers have developed a new medical therapy that could protect people with cardiovascular disease by boosting the body's natural defences. The treatment, which is based on a peptide called apelin, has shown promising results in mice and humans, reducing mortality rates and improving health outcomes.

SourceUniversity of Alberta Faculty of Medicine & Dentistry·JournalProceedings of the National Academy of Sciences·DateJun 13, 2019

US soldiers have worse heart health than civilians

A new study found that US soldiers have worse cardiovascular health compared to civilians of similar ages, particularly in blood pressure. The researchers, who analyzed data from over 263,000 active duty Army personnel and a representative civilian population, aimed to identify areas for improvement.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateJun 5, 2019

Sleepless nights linked to high blood pressure

A study published in Psychosomatic Medicine found that a bad night's sleep can lead to a spike in blood pressure, even on the following day. Researchers wore portable blood pressure cuffs and actigraphy monitors on participants to measure the impact of sleep efficiency on cardiovascular health.

SourceUniversity of Arizona·JournalPsychosomatic Medicine·DateJun 4, 2019

Beta blockers reduce stress-induced irregular heart rhythm

A new study by Yale researchers found that beta blockers can minimize the impact of negative emotions on heart rhythm in individuals with a history of atrial fibrillation. The medication reduced the risk of AFib episodes triggered by stress and anger, while still having an effect on those taking beta-blockers.

SourceYale University·JournalHeartRhythm Case Reports·DateJun 4, 2019

New research addresses incidence of atrial fibrillation after aortic valve replacement

Researchers found that approximately 50 percent of hospitalizations for both TAVI and surgical aortic valve replacement were associated with the development of new atrial fibrillation. Hospitalizations with new atrial fibrillation had higher odds of in-hospital stroke and in-hospital death compared to those without, highlighting the ne...

SourceUniversity of Alabama at Birmingham·JournalJAMA Internal Medicine·DateJun 3, 2019

SCAI releases multi-society endorsed consensus on the classification stages of cardiogenic shock

A new five-stage system defines cardiogenic shock based on narrative patient descriptions, physical findings, and biochemical/hemodynamic markers to facilitate rapid assessment and communication between providers. The consensus aims to standardize vocabulary, recognize risk for adverse outcomes, and inform interventions.

SourceSociety for Cardiovascular Angiography and Interventions·JournalCatheterization and Cardiovascular Interventions·DateMay 20, 2019

Novel technique reduces obstruction risk in heart valve replacement

Researchers developed a novel technique called LAMPOON to prevent left ventricular outflow tract obstruction, a common complication of transcatheter mitral valve replacement. The study found that the new method increased treatment options for high-risk patients and achieved better survival rates compared to other methods.

SourceNIH/National Heart, Lung and Blood Institute·JournalJournal of the American College of Cardiology·DateMay 20, 2019