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Atomic-scale simulation of antiarrhythmic drug interaction with cardiac cells

Researchers at UC Davis developed a novel simulation that provides insights into vital atomic-scale drug-cardiac cell interactions. The study advances the development of new antiarrhythmic drugs targeting voltage-gated sodium channels, which can help predict individual patient responses to drug therapy.

SourceUniversity of California - Davis Health·JournalProceedings of the National Academy of Sciences·DateFeb 6, 2019

Predicting leaky heart valves with 3D printing

Researchers at Harvard University have developed an integrated 3D printing and valve sizing system to predict leaky heart valves during aortic valve replacement procedures. The system uses CT scan data to create physical models of individual patients' aortic valves, allowing cardiologists to determine the perfect replacement valve size.

SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalJournal of Cardiovascular Computed Tomography·DateDec 10, 2018

Racial disparities in sudden cardiac death rates cannot be explained by known risk factors

A study published in the Journal of the American College of Cardiology found that black patients remain at significantly higher risk for sudden cardiac death even after adjusting for income, education, smoking, and other risk factors. The researchers suggest that unknown genetic factors may be contributing to these disparities.

SourceUniversity of Pennsylvania School of Medicine·JournalJournal of the American College of Cardiology·DateNov 12, 2018

An end to arachnophobia 'just a heartbeat away'

A new study found that exposing people with phobias to their fear at the exact time of their heartbeats significantly reduces phobia severity. Researchers combined computerized therapy with online heart rhythm measurements to treat patients with spider phobia, showing improved anxiety levels and reduced physiological responses.

SourceUniversity of Sussex·JournalPsychosomatic Medicine·DateOct 30, 2018

Donor hearts at increased disease risk offer better survival rates for transplant recipients

Researchers found that accepting an organ from a donor at higher risk of disease transmission offers a higher one-year survival rate for candidates on the heart transplant list. Patients who decline such offers may wait longer or become too ill to undergo the procedure, resulting in higher mortality rates.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateOct 29, 2018