A new HIV therapy has been shown to reduce viral replication and increase immune cells in individuals with advanced, drug-resistant HIV infection. The study found that nearly half of patients experienced viral load suppression at six months, making it a promising option for those with multi-drug resistance.
A NOAA-funded team of scientists from Scripps Institution of Oceanography and the University of Delaware discovered the missing 75-foot stern section of the USS Abner Read in 290 feet of water off Kiska Island. The finding sheds light on the little-known episode in WWII history where 71 US Navy sailors lost their lives.
A large population-based study identified variations in the tongue microbiota among community-dwelling elderly adults in Japan, showing an association with tooth conditions. The study found that a specific group of commensal bacteria were more predominant in those with fewer teeth and dental caries.
Research found that people who believe they were unwanted or unplanned pregnancies tend to have more insecure relationship styles as adults. This perceived birth status affects attachment styles, leading to increased anxiety and avoidance in relationships. The study suggests that revealing such information can increase insecurities and...
Researchers have gained new understanding of how autophagosomes seal off waste material, with a key role identified for ESCRT complexes. This breakthrough could lead to new cancer treatments by inhibiting autophagy closure.
Researchers at the University of Delaware discovered that plants emit scent cues when under attack by insects, recruiting birds to provide a food source while defending crops. The study used Play-Doh larvae and dispensers to replicate plant volatiles, finding that birds were attracted to these cues more strongly than to a control measure.
Researchers uncover evidence of prehistoric embalming process in ancient Egyptian mummy dating back to 3700-3500 BC. The 'recipe' contained antibacterial agents used in similar proportions as later Egyptian embalmers, revealing a wider geographical use of these balms.
Researchers at the University of Missouri-Columbia found that grouping children by similar social abilities, rather than disability or disorder, leads to better behavior outcomes. This approach allows peers to learn from and support each other in improving their social skills.
Researchers have developed a novel statistical method called AA9int to evaluate gene-to-gene interactions associated with cancer and other complex diseases. This approach identifies combinations of genetic variants for predicting cancer risk and prognosis, increasing our understanding of the biological mechanisms of cancer development.
NASA-NOAA's Suomi NPP satellite detected Tropical Depression 14E in the Eastern Pacific Ocean on August 14. The depression is moving west at 14 mph and is expected to become a tropical storm over the next few days, with gradual strengthening forecast.
Researchers at Utah State University have developed a new flavonoid molecule that can release carbon monoxide in a controlled manner, triggering cancer cell death and reducing inflammation. The unique molecules are trackable, targetable, and triggerable using visible light.
A study by Arizona State University found that 99% of science students appreciate instructor humor, which improves the classroom experience, reduces stress, and enhances relationships. However, men and women have different preferences for what is considered funny or offensive.
A social-psychological study at Goethe University Frankfurt reveals that while social class influences behavior, the communication situation plays a more significant role in shaping behavior towards counterparts from different social classes. The study found that individuals exhibit solidarity with those from lower social classes and a...
A recent study found that installing wildlife crossing structures over highways has increased the success rate of pronghorn crossings, reducing wildlife-vehicle collisions by 70 percent. Pronghorn adapted to using these structures within four years, increasing their crossing success rates and decreasing stress levels.
Researchers have discovered a potential alternative to liver transplant for patients with acute liver failure, which is triggered by liver injury and can be life-threatening. A new therapy using anti-cancer drugs has been shown to regenerate the liver in mouse models, preventing death from liver injury.
A new chemical compound has been developed and tested by scientists at the University of Huddersfield, which attracts vulnerable cancer cells while leaving healthy cells untouched. The compound contains ruthenium and is showing promising results in laboratory tests.
The study will recruit 400 newborns with a wide variety of possible genetic disorders, comparing whole genome sequencing to targeted genomic sequencing for accuracy and effectiveness. The researchers aim to determine if the targeted panel can be safely integrated into newborn care, eliminating ethical dilemmas and saving healthcare costs.
Researchers have identified 85 genes essential for fission yeast cells to maintain their ability to divide after being starved of nitrogen. The study sheds light on the genetic network required for resting cells like cancer stem cells to reactivate and has potential applications in developing new therapies to treat cancer. This discove...
Researchers used data from robotic floats to find that open water near Antarctica releases more carbon dioxide than thought, contradicting previous studies. The study aims to improve our understanding of the Southern Ocean's role in regulating the global climate.
A new study found widespread logging permit fraud in the Brazilian Amazon, which is undercutting conservation efforts and threatening high-value timber species like ipe. The researchers discovered a deliberate overestimation bias of these species, indicating corruption or simple misidentification.
A study found that people with prediabetes who prefer to be active and alert later in the day tend to have higher body mass indices compared to those with morning preferences. This association is partly due to lack of sufficient sleep, which can increase the risk of obesity and diabetes.
Researchers found that RUNX proteins bind to DNA damage sites and co-regulate the recruitment of DNA repair protein FANCD2. This discovery could lead to the development of synthetic-lethal approaches to attack RUNX-deficient cancers, including solid tumours of the breast and leukemia.
Researchers at Mount Sinai have successfully restored vision in mice by activating retinal stem cells, which could lead to treatments for patients with blinding diseases. The study found that new rod photoreceptor cells were generated and integrated into the existing retinal structure, restoring function of the visual pathway.
The study discovered that patients' primary motivations behind cosmetic procedures are physical health, psychological well-being, and aesthetic appearance. Patients primarily pursue these procedures to look younger, fresher, and more confident.
A review by Yale psychologist Yarrow Dunham suggests that ingroup bias is a natural phenomenon driven by membership in a social group, explaining why people favor their own group over others. This bias may have evolved to boost group living and social learning.
A study published in Nature Scientific Reports found that nuclear DNA analysis can highlight genetic differences between sardine populations, contradicting previous conclusions based on mitochondrial DNA analysis. This new understanding has significant implications for fisheries management and conservation strategies.
A new OU study shows that climate warming accelerates temporal turnover rates of soil bacterial and fungal communities, affecting ecosystem predictability. The research finds divergent succession of microbial communities under climate warming, with reduced stochasticity and dynamic drivers.
Researchers use light patterns to control bacterial swimming speed and shape, creating 'microbricks' for building microscopic devices. The genetically modified bacteria can be used as living propellers to transport small biological cargoes.
A new drug repurposing study has identified two commonly prescribed medications that may increase the risk of heart disease. Hydroxychloroquine, an anti-rheumatic drug, was found to be associated with lower rates of coronary artery disease, while carbamazepine, a medication for epilepsy and neuropathic pain, may increase the risk.
Researchers have identified three known SNAREs and a new protein Ykt6 as essential for the fusion of autophagosomes with vacuoles, allowing for efficient cellular waste recycling. This breakthrough study sheds light on the molecular mechanisms underlying autophagy, a vital process in maintaining cellular homeostasis.
Researchers at Washington State University discovered that cancer-fighting drugs can slow or stop fungal infections in plants by activating genes used to defend against pathogens. The study showed two different results from the applications of DNA-specific drugs on pea tissue, with differing mechanisms of action.
Scientists at Michigan State University have discovered a navigational gene in glass catfish that responds to magnetic waves, which may one day be used to treat Parkinson's and epilepsy. The gene, called the electromagnetic-perceptive gene, can be activated using magnets and has shown promise in controlling movement in mice.
Researchers have discovered a link between MUC16 gene mutations and higher tumor mutation loads in gastric cancer patients, which may improve response rates to immunotherapy. The study's findings could open up new treatment options for up to 38% of gastric cancer patients.
A study published in JAMA Network Open found that physicians who showed unburied empathy during care conferences had more effective conversations with families, leading to better patient outcomes. The researchers recommend slowing down, using the 'NURSE' mnemonic, and avoiding transitions like 'but' to improve empathetic communication.
A team of astronomers led by George Becker found that 12.5 billion years ago, the most opaque region in the universe had relatively little matter. The discovery sheds light on how galaxies formed and altered their surroundings in the early universe.
Tropical Storm Bebinca continues to linger near Hainan Island as seen in NASA-NOAA's Suomi NPP satellite image on August 14. The storm is expected to make landfall in northern Vietnam with maximum sustained winds near 35 knots.
A recent study published in Molecular & Cellular Proteomics has uncovered changes in TB strains that make them vulnerable to other antibiotics. The research also reveals a potential target for developing new drugs against isoniazid-resistant tuberculosis.
Researchers at Scripps Research have found an enzyme, YRSACT, that increases megakaryocyte production, the precursors to platelets. This discovery offers a new therapeutic option for treating thrombocytopenia, a condition characterized by low platelet counts and increased risk of internal bleeding.
A study by the Technical University of Munich found that European trees' wood density has decreased continuously since 1870, despite increased growth. The decrease in wood density is attributed to factors such as rising temperatures and nitrogen input from agriculture and industry, affecting forest ecosystems.
A new method predicts mean air temperature will be abnormally high in 2018-2022, higher than figures inferred from anthropogenic global warming alone. This is due to a low probability of intense cold events and a high probability of heat events, leading to increased tropical storm activity.
A new class of proteins called E3 ubiquitin ligases has been shown to reduce drug-seeking behaviors in a preclinical study. Smurf1, one of these proteins, is targeted to prevent cocaine addiction relapse.
Challenges facing ID physician scientists include inadequate funding for fellowship opportunities and steep compensation disparities, leading to a decline in trainees pursuing careers as physician researchers. To address this, medical societies recommend expanded mentorship, training opportunities, and workforce diversity measures.
Researchers at Rice University and the University of Houston created models to predict the output of custom-built genetic circuits, enabling unprecedented precision in programming microorganisms. The models can be used to design microbes for complex environments, such as the gut microbiome or soil, and improve the controllable manufact...
A study from the Francis Crick Institute found that chemicals produced by vegetables like kale and broccoli can prevent colon cancer in mice. The research discovered that these compounds activate a protein called AhR, which helps protect against inflammatory responses to gut bacteria.
A new study published in Rheumatology indicates that exposure to secondhand smoke in childhood increases the risk of developing rheumatoid arthritis as an adult. The study found that passive smoking during childhood can lead to an increased risk of arthritis and earlier onset, even in non-smokers.
Researchers have created new 'switches' that respond to light using combined light-sensitive molecules with layers of graphene and other 2D materials. This technology could lead to programmable applications in smart electronics, sensors, and flexible devices.
A NASA team, led by Emily Wilson, is launching a low-Earth-orbiting CubeSat mission called Mini-Carb to measure atmospheric greenhouse gases. The mini-LHR instrument, made of commercial parts, can simultaneously measure carbon dioxide, water vapor, and methane in the atmosphere's limb.
Researchers discovered elephants' ability to resist cancer stems from the 'zombie LIF6' gene, which kills cells poised to become cancerous. This strategy may inspire new treatments for humans by mimicking the gene's behavior or activating its existing copies.
A new study finds that only a few areas in Africa are suitable for palm oil production without harming primate populations, raising concerns about the industry's impact on conservation. The research highlights the need for sustainable practices and policy initiatives to mitigate large-scale deforestation.
A randomized clinical trial found that a pill containing low doses of three antihypertensive drugs resulted in a greater percentage of patients achieving their target blood pressure goal. The study included 700 patients in Sri Lanka who were not receiving treatment or taking one medication.
Researchers found that a small fraction of protons in neutron-dense objects significantly impact their stiffness, mass-to-size ratio, and cooling process. Protons are believed to determine several properties of the star due to their high energy content.
A new study using data from diving robots reveals that Antarctic winter seas exhale significantly more carbon dioxide than previously believed. The Southern Ocean is currently near neutral with respect to removal of carbon from the atmosphere, contrary to previous studies.
A study by Ulrike Rohn and Mats Nylund reveals that TV audiences create value through sharing activities, including distribution, interaction, and audience circulation. Successful TV providers must provide a platform for audience input, stimulate engagement, and promote viral sharing.
A phase 1 clinical trial at the University of Colorado Cancer Center has shown promising results, with 72% 2-year survival in heavy smokers. The combination of olaparib, cetuximab, and radiation was found to be synthetically lethal for cancer cells, leading to enhanced cell death.
A new study reveals severe declines in mountain hare populations on Scottish grouse moors, with numbers decreasing by nearly 5% every year from 1954 to 1999. The decline accelerated dramatically between 1999 and 2017, with counts in 2017 showing less than one percent of original levels.
A new uncertainty relation has been discovered, linking the precision of temperature measurements to quantum mechanics. This discovery establishes a connection between quantum uncertainty and the accuracy of nanoscale thermometers.
A study reveals a widening wage gap between hospital CEOs and medical staff, with CEO salaries increasing by 93% while doctor and nurse wages rose by 26-15%. The cost-burden of nonclinical workers contributed to the growth in healthcare costs, with nationwide expenditures reaching $3.2 trillion in 2015.
Researchers detected higher levels of chemical substances in Africanized honeybee brains than in gentler strains, triggering irascible behavior. The compounds also regulate food intake and digestion in flies and mice, illustrating molecular mechanisms underlying different species' behavior evolution.
The grant enables researchers to detect and identify a wide range of molecules from diverse samples. The instrument will also support the university's goal of increasing participation by underrepresented groups in STEM education and research.
Researchers have discovered new genes that may contribute to the development of Alzheimer's disease, a complex condition characterized by neurodegeneration and memory decline. The study identified rare variations in genes associated with an inflammatory response and changes in protein production.