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Researchers learn how to steer the heart -- with light

A team of researchers from Oxford and Stony Brook universities has developed a way to precisely control electrical waves in heart cells using light. This allows for fine control over wave speed, direction, and orientation, enabling unprecedented direct control of organ-level function without manipulating individual cells.

SourceUniversity of Oxford·JournalNature Photonics·DateOct 19, 2015

Blood clots may complicate aortic valve replacements

A new study from the Cedars-Sinai Heart Institute shows that about 15% of patients with bioprosthetic aortic heart valves develop blood clots on the leaflets, which can impair valve motion. However, anti-coagulation medications like Warfarin quickly resolve the issue for all patients, regardless of the type of valve or procedure.

SourceCedars-Sinai Medical Center·JournalNew England Journal of Medicine·DateOct 5, 2015

Predicting arrhythmias so as to prevent them

Scientists have discovered a method to predict certain types of cardiac arrhythmias, allowing for potential prevention and improved heart health. The researchers used mathematical modeling to analyze the transition from normal to abnormal heartbeat patterns in embryonic chicken cells.

SourceMcGill University·JournalProceedings of the National Academy of Sciences·DateSep 28, 2015

What powers the pumping heart?

Scientists have identified 500 novel membrane proteins that play a critical role in normal heart function and may help uncover new information about heart failure and arrhythmias. The research focuses on protein Tmem65, which regulates communication between cardiac contractile cells.

SourceUniversity of Toronto·JournalNature Communications·DateSep 25, 2015

Extracorporeal life support is 'bridge-to-life' for patients with sudden onset cardiogenic shock

Researchers found that patients with acute cardiogenic shock who received extracorporeal life support had better cardiac recovery rates compared to those with chronic conditions. The study showed a 59% survival rate for patients in the acute group, while only 14% survived in the chronic group.

SourceAmerican Association for Thoracic Surgery·JournalJournal of Thoracic and Cardiovascular Surgery·DateAug 20, 2015

Surgeons refine procedure for life-threatening congenital heart defect

Researchers analyzed 43 patients with hypoplastic left heart syndrome (HLHS) who underwent either an arterial or venous shunt as part of the hybrid palliation procedure. The study found that the arterial shunt group showed better pulmonary arterial growth, shorter surgical times, and higher oxygen saturations at discharge. However, no ...

SourceAmerican Association for Thoracic Surgery·JournalJournal of Thoracic and Cardiovascular Surgery·DateAug 13, 2015

Early surgery for mitral regurgitation, before clinical triggers emerge, has best outcomes

A study published in the Journal of Thoracic and Cardiovascular Surgery found that delaying surgery for severe mitral regurgitation until symptoms appear doubles the risk of postoperative mortality and heart failure. Early surgery, on the other hand, provides the best long-term outcomes, with lower mortality and congestive heart failur...

SourceAmerican Association for Thoracic Surgery·JournalJournal of Thoracic and Cardiovascular Surgery·DateAug 11, 2015

Southern diet could raise your risk of heart attack

A recent study published in Circulation found that a traditional Southern-style diet is associated with a higher risk of heart disease. Researchers analyzed data from over 17,000 adults and found that those who consumed foods conforming to the Southern dietary pattern had a 56% higher risk of heart disease compared to those who ate it ...

SourceAmerican Heart Association·JournalCirculation·DateAug 10, 2015

Can we restart the heart?

San Diego State University researchers have developed a way to use biotechnology to rejuvenate cardiac progenitor cells, which replicate indefinitely into new heart cells. By overexpressing an enzyme associated with cancer cell growth, they've shown promise in increasing cell proliferation and lifespan in mice, as well as human tissue.

SourceSan Diego State University·JournalBiological Chemistry·DateJul 29, 2015

One in 4 patients with defibrillators experiences boost in heart function over time

A Johns Hopkins-led study of 1,200 people with implanted defibrillators shows that within a few years, one-quarter experienced substantial improvements in heart function, reducing the risk of arrhythmia and device shocks. Improved heart function was primarily attributed to concurrent use of heart failure medications and pacemakers.

SourceJohns Hopkins Medicine·JournalJournal of the American College of Cardiology·DateJul 27, 2015

Societies issue recommendations for left atrial appendage occlusion

The American College of Cardiology has released recommendations for the implantation of left atrial appendage occlusion devices, which may lower the risk of stroke in patients with atrial fibrillation. The new guidelines emphasize team-based care and the need for robust clinical data on outcomes for patients treated with these devices.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateJun 29, 2015

Lower heart rate variability turns women off

A new study published in Applied Psychophysiology and Biofeedback found a significant link between lower heart rate variability and sexual dysfunction in women. Women with below-average heart rate variability were more likely to report sexual arousal problems and overall sexual difficulties.

SourceSpringer·JournalApplied Psychophysiology and Biofeedback·DateJun 17, 2015

Tiny heart, big promise

Researchers at Children's Hospital Los Angeles identified a new source of cells that can develop into coronary vessels and found the signaling protein CXCL12 guiding this process. The study may have clinical relevance, helping diagnose abnormal coronary vessels and developing interventional strategies to prevent heart attacks.

SourceChildren's Hospital Los Angeles·JournalDevelopmental Cell·DateMay 26, 2015

Activity after ICD implantation may predict survival

Researchers found that patients with higher activity levels after ICD implantation had a 40% lower risk of death at four years compared to those with lower activity. The study analyzed over 98,000 patients and showed that even small increases in activity were associated with a significant reduction in mortality.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateMay 15, 2015