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Resuscitation science tip sheet

Research presented at the American Heart Association's Scientific Sessions 2014 found that implementing pre-arrival telephone CPR guidelines in Arizona increased bystander CPR rates by 41% and survival rates by 42%. The study also showed that women are more likely to survive sudden cardiac arrest compared to men.

Getting to the heart of the heart

Researchers at Johns Hopkins University have captured images of the complex, revealing the connection between some genetic mutations and electrical abnormalities in the heart. The study provides a starting point for designing therapies to treat conditions such as long QT syndrome and Brugada syndrome.

SourceJohns Hopkins Medicine·JournalNature Communications·DateNov 5, 2014

Heart's own immune cells can help it heal

Researchers found that beneficial immune cells originate in the embryonic heart and can promote regeneration, while harmful macrophages come from the bone marrow. Blocking the influx of bone marrow-derived macrophages protects the resident macrophages, allowing them to promote repair and reduce inflammation.

SourceWashU Medicine·JournalProceedings of the National Academy of Sciences·DateOct 30, 2014

Stress may be harder on women's hearts than men's

Researchers found that mental stress can cause reduced blood flow to the heart in women, leading to ischemia, a prevalent component of cardiovascular disease. The study suggests sex distinctions in how the body responds to mental stress, with women experiencing increased negative emotions and decreased positive feelings.

SourceDuke University Medical Center·JournalJournal of the American College of Cardiology·DateOct 13, 2014

Modest acute changes in cardiac biomarkers and electrocardiogram findings following thoracic radiation therapy

Researchers found modest acute changes in cardiac biomarkers and electrocardiogram findings following thoracic radiation therapy, but no clinically significant cardiac events. The study suggests that longer follow-up and increased dose range may reveal the impact of radiation on late RT-related toxicity.

SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateSep 24, 2014

Variability keeps the body in balance

The study, published in the Proceedings of the National Academy of Sciences, uses control theory to analyze heart rate data from athletes and found that a healthy heart must maintain certain patterns of variability during exercise to keep the body in balance. This variability is essential for maintaining homeostasis and preventing fati...

SourceCalifornia Institute of Technology·JournalProceedings of the National Academy of Sciences·DateSep 22, 2014

2014 ESC/ESA Guidelines on non-cardiac surgery: Cardiovascular assessment and management

The 2014 ESC/ESA Guidelines provide recommendations for cardiovascular assessment and management in non-cardiac surgery, aiming to reduce complications. The guidelines cover risk assessment models, biomarkers, anticoagulants, statins, aspirin, and beta-blockers to mitigate cardiac risk in patients undergoing non-cardiac surgery.

SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·DateAug 1, 2014

Dementia patients more likely to get implanted pacemakers, says Pitt study

A study by University of Pittsburgh researchers found dementia patients are more likely to receive a pacemaker for atrial fibrillation than those without cognitive impairment, despite being diagnosed with less aggressive interventions. The likelihood was highest among dementia patients, even after accounting for clinical factors.

Healing the heart with fat

Researchers discovered that a particular EPA metabolite, 18-hydroxyeicosapentaenoic acid (18-HEPE), plays a crucial role in protecting against cardiovascular diseases. This metabolite was produced by immune cells and confirmed its heart-protective effects.

SourceRockefeller University Press·JournalJournal of Experimental Medicine·DateJul 21, 2014

Adults can undo heart disease risk

A Northwestern Medicine study found that adults who adopt healthy lifestyle behaviors in their 30s and 40s can control and potentially reverse coronary artery disease. The study also showed that losing healthy habits as they age leads to a measurable negative impact on heart health.

SourceNorthwestern University·JournalCirculation·DateJun 30, 2014