Ileum

Terminal ileum intubation and biopsy in routine colonoscopy practice

The study found that terminal ileum intubation significantly increases the diagnostic yield for inflammatory bowel disease, anemia, abdominal pain, and chronic diarrhea. Routine ileal biopsy is recommended during colonoscopy for patients with abnormal mucosal findings or red-flag symptoms.

Diagnosing pediatric Crohn disease with radiomic and clinical data

A radiomic-based model using T2-weighted MRI data achieved high accuracy in diagnosing pediatric Crohn disease, outperforming expert radiologists. The model was ensembled with clinical data to further improve performance.

$3.6 million grant backs effort to better treat Crohn’s disease

Researchers at UVA Children's will use a sophisticated computer model to better understand and treat Crohn's disease, which can have lifelong consequences for young patients. The team hopes to identify biological markers or metabolic signatures that can be used for early diagnosis and personalized medicine.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

No IgA leads to intestinal inflammation in mice

Researchers from Tokyo Medical and Dental University found that IgA deficiency causes substantial inflammation in the ileum of mice, making them susceptible to disease. The study reveals IgA plays a protective role in maintaining gut health by regulating microorganisms.

Scientists explain why Crohn disease is localized to specific regions of the gut

Researchers found that intestinal bacteria in the terminal ileum activate p40 expression, leading to chronic inflammation and predisposing this region to Crohn's disease. The study provides a molecular explanation for why Crohn's disease often affects the small intestine.