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Decoding the gut with snRNA-seq: insights into immunity and nutrient absorption in wild boars and domestic pigs

Researchers created a comprehensive single-nucleus transcriptomic atlas of the pig intestine, identifying 19 major cell types and 58 cellular subtypes. This study provides valuable insights into the mechanisms by which neurons regulate inflammatory responses and the molecular basis for stronger immune functions in wild boars.

SourceScience China Press·JournalScience China Life Sciences·DateSep 28, 2025

Comprehensive metagenomic survey reveals vast gut microbiome diversity and antibiotic resistome across 14 mammal species on the Tibetan Plateau

This comprehensive metagenomic survey reveals vast gut microbiome diversity, with 21,902 species-level genome bins identified. The study also uncovers a significant reservoir of previously uncharacterized microbes and identifies high-risk antibiotic resistance genes across 14 mammal species.

SourceScience China Press·JournalScience China Life Sciences·DateSep 25, 2025

Benchmark study tracks trends in dog behavior

A new Virginia Tech study analyzes four years of owner-reported data from over 47,000 dogs to establish a baseline for understanding dog behavior on a large scale. The research reveals that dogs are adaptable and shows no substantial changes in behavioral profiles despite the COVID-19 pandemic.

SourceVirginia Tech·JournalPLOS One·DateSep 10, 2025

What can prairie dogs teach us about wildfire management?

Research suggests that black-tailed prairie dogs can reduce wildfire behavior by altering landscape features and promoting the growth of fire-resistant vegetation. By incorporating prairie dog activity into fire behavior models, land managers could develop more effective strategies for prevention and mitigation.

SourceUniversity of Arizona·JournalBioScience·TypeLiterature review·DateAug 25, 2025

RNA immunity: An overlooked antiviral defense in mammals

Emerging evidence highlights the involvement of extracellular RNAs in the antiviral defense process, with microRNAs binding viral genomes via base-pairing interactions to inhibit expression. RNA immunity represents a complementary arm of the mammalian immune system, functionally independent of traditional protein-based defenses.

SourceScience China Press·JournalScience Bulletin·DateAug 7, 2025

Animal behavior: Dog TV viewing habits vary by personality

Research found that dog TV viewing habits differ by personality, with excitable dogs more likely to follow on-screen objects and fearful dogs reacting to car horns or doorbells. The study, published in Scientific Reports, suggests that engaging with TV could provide dogs with an enriching experience.

SourceScientific Reports·JournalScientific Reports·TypeObservational study·DateJul 17, 2025

Gut morphology, not just diet or phylogeny, shapes mammalian gut microbiomes

Researchers analyzed over 1,400 gut microbiome samples from 292 mammalian species to find distinct gut microbiomes corresponding to different gut morphology types. These microbiomes were grouped into three enterotypes: Fusobacterium in simple-gut species, UCG-005 in foregut fermenters, and Prevotella in hindgut fermenters.

SourceScience China Press·JournalScience China Life Sciences·TypeMeta-analysis·DateJul 10, 2025

Feral-free zones spark small mammal boom in Australian desert

A 26-year study found that removing feral animals like cats and foxes from a reserve sparked an ecological transformation, favoring the growth of smaller rodents like Bolam's mouse and spinifex hopping mouse. Larger species like plains mouse and stripe-faced dunnart also surged in population after five to nine years.

SourceUniversity of New South Wales·JournalProceedings of the Royal Society B Biological Sciences·TypeExperimental study·DateJul 10, 2025

New discovery in small primate could pave the way for im-proved stem cell therapies

Researchers have discovered adult stem cells from a non-human primate that closely resemble human biology, offering new potential treatment targets for diseases. The discovery uses a novel computational method to identify the optimal animal model, reducing animal usage and paving the way for more effective stem cell therapies.

SourceAarhus University·JournalNature Communications·TypeExperimental study·DateJul 8, 2025

Do red squirrels and dormice get along?

A study by University of Göttingen researchers found that mixed deciduous-conifer forests promote coexistence between red squirrels and dormice. The team observed both species living side by side in these forests, suggesting a potential role for mixed forest management in supporting biodiversity.

SourceUniversity of Göttingen·JournalEuropean Journal of Wildlife Research·TypeObservational study·DateJul 3, 2025

Safely navigating treetops thanks to a scaly tail

Researchers from Empa's Soft Kinetic group studied the rare scaly-tailed squirrels' unique bodily structure, discovering that their thorn-covered scales help them maintain position and grip onto tree bark. The study aims to inform robotics by adopting morphological structures and behaviors honed through millions of years of evolution.

SourceSwiss Federal Laboratories for Materials Science and Technology (Empa)·JournalJournal of The Royal Society Interface·TypeExperimental study·DateJul 2, 2025

Chicago’s rodents are evolving to handle city living

Researchers found that chipmunks' skulls became larger but teeth shorter due to increased human food availability. Voles' auditory bullae decreased in size possibly to dampen environmental noise. These changes demonstrate the profound impact of humans on wildlife and their environment.

SourceField Museum·JournalIntegrative and Comparative Biology·DateJun 26, 2025

The purrfect gene

A study published in PLOS One reveals that cats' purring behavior is linked to genetic variation, specifically the short-type androgen receptor gene. Cats with this gene exhibit higher owner-assessed purring scores than those with the long-type gene.

SourceKyoto University·JournalPLOS One·TypeObservational study·DateMay 29, 2025

Gelada monkeys understand complex "conversations" involving distress calls and prosocial comforting responses, exhibiting surprise when such vocal exchanges are manipulated to violate their expectations

In a study published in PLOS, gelada monkeys demonstrated an understanding of complex vocal exchanges involving distress calls and prosocial comforting responses. The monkeys exhibited surprise when such vocal exchanges were manipulated to violate their expectations.

SourcePLOS·JournalPLOS One·DateMay 14, 2025

Piecing together the brain puzzle

A new microscopy method, LICONN, developed by ISTA scientists and Google Research, can reconstruct mammalian brain tissue with all synaptic connections between neurons. This technique uses standard light microscopes and hydrogel to achieve high resolution and opens up possibilities for visualizing complex molecular machinery.

SourceInstitute of Science and Technology Austria·JournalNature·TypeImaging analysis·DateMay 7, 2025

Beyond the double helix: Alternative DNA conformations in ape genomes

A team of researchers has comprehensively predicted the location of non-B DNA structures in great apes using newly available telomere-to-telomere genomes. The study suggests that non-B DNA is enriched in these segments and may play a role in genetic diseases and cancer, with potential new functions discovered.

SourcePenn State·JournalNucleic Acids Research·TypeExperimental study·DateApr 24, 2025

Yonatan Stelzer earns the 2025 ISSCR Outstanding Young Investigator Award for his breakthrough approaches to addressing fundamental problems in mammalian development

Dr. Yonatan Stelzer has made significant contributions to understanding epigenetic mechanisms and embryonic development, challenging conventional knowledge with innovative approaches. His research aims to establish fully data-driven quantitative models of spatiotemporal processes in mammals.

Protected habitats aren’t enough to save endangered species

A recent study published in PLOS Biology found that even within protected habitats, tropical species are still vulnerable to threats from beyond their borders. Human population density and habitat disturbance in surrounding areas can lead to a decline in species richness by up to 1% per 16 persons per square kilometer.

SourcePLOS·JournalPLOS Biology·TypeObservational study·DateFeb 13, 2025

Comprehensive global study shows pesticides are major contributor to biodiversity crisis

A comprehensive global study reveals pesticides are a major contributor to the biodiversity crisis, affecting over 800 species of plants, animals, fungi, and microbes. The research highlights the need for policies and practices to reduce pesticide use, including regenerative agriculture and Integrated Pest Management.

SourceUK Centre for Ecology & Hydrology·JournalNature Communications·TypeMeta-analysis·DateFeb 13, 2025

Macaque monkeys can learn to associate pictures with sounds and words, even when the words are then spoken by new individuals, showing impressive abilities to learn cross-modal associations

In a groundbreaking study, macaque monkeys demonstrated the ability to form connections between visual images and auditory signals, as well as verbal cues. This remarkable capacity for cross-modal learning was observed even when the spoken words were presented by new individuals.

SourcePLOS·JournalPLOS One·DateFeb 12, 2025

Syrian hamsters reveal genetic secret to hibernation

Researchers at Hokkaido University have identified a key gene, glutathione peroxidase 4 (Gpx4), that enables Syrian hamsters to survive extreme cold by limiting cellular damage. The discovery could lead to new treatments for human health, such as improving organ preservation and using hypothermia as a therapeutic tool.

SourceHokkaido University·JournalCell Death and Disease·TypeExperimental study·DateSep 30, 2024

Fitness loss through spontaneous mutations will not impact viability of human populations in the near future

A new study using a mammal model suggests that fitness loss through spontaneous mutations will not significantly affect human populations. The research indicates that even without natural selection, the rate of fitness decline is not a cause for concern, providing reassurance about human viability in the near future.

SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateSep 26, 2024

What’s for dinner? Scientists unearth key clues to cuisine of resident killer whales

Researchers analyzed DNA in fecal samples to determine the diet of Alaska and southern resident killer whales. They found that both populations prefer salmon, but differ in when they switch to hunting other fish species. The study provides key insights into the delicate balance between regional abundance of different fish species.

SourceUniversity of Washington·JournalRoyal Society Open Science·TypeObservational study·DateSep 19, 2024

How zebrafish map their environment

Researchers have found evidence for place cells in zebrafish brains, allowing them to create internal maps of their environment. The brain region, telencephalon, is also thought to be analogous to the mammalian hippocampus and plays a key role in spatial orientation, social networks, and memory.

SourceMax-Planck-Gesellschaft·JournalNature·DateSep 3, 2024