Articles tagged with Saliva
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Researchers found that self-collected saliva samples can reliably detect SARS-CoV-2 genetic material at a rate similar to nasopharyngeal and oropharyngeal swabs. The study also showed that saliva samples remained stable for up to 24 hours, providing a cheaper and less invasive option for COVID-19 testing.
Researchers discovered that cowpea plants harbor receptors on their cells that can detect caterpillar saliva, triggering anti-herbivore defenses. The discovery sheds light on how plants activate their immune systems to defend against hungry insects.
A new study by UCF researchers found that people with congested noses and full sets of teeth are more likely to spread viruses like COVID-19. The study used computer-generated models to simulate sneezes in different types of people, finding that these features can increase the distance droplets travel and linger in the air.
A new paper in Cell Reports breaks down the details of how salivary glands collectively produce proteins found in saliva. The study identifies which proteins are produced by each type of gland and shows that individual cells within a single gland can secrete different proteins.
Researchers analyzed saliva samples from over 500 participants to identify microRNA levels that could indicate a concussion. The study found that measuring these molecules in saliva can aid diagnosis with high accuracy, potentially replacing current symptom scales and neurocognitive tests.
A yearlong study is being conducted to find the percentage of frontline workers positive for COVID-19, the duration of immunity, and whether antibodies produced protect against reinfection. The study aims to identify the most potent antibodies and develop effective vaccines using monoclonal antibodies.
A recent study by ETH Zurich researchers found that workplace interruptions lead to increased cortisol levels and physical stress. Participants who received chat messages from superiors during a task reported better emotional and cognitive responses to stress.
Scientists at the University of Technology Sydney have developed a highly sensitive saliva test for SARS-CoV-2 virus antigens, detecting presence in under 15 minutes. The test aims to identify contagious individuals before symptoms appear, enhancing contact tracing and disease management.
Researchers found that COVID-19 patients can retain antibodies in their saliva and blood for at least three months. The study used saliva and blood samples from over 100 patients to measure antibody levels, showing that IgG antibodies bind to the SARS-CoV-2 spike protein are detectable for 115 days.
Researchers found that IgG antibodies remain stable for up to 105 days after symptom onset in COVID-19 patients, while IgA and IgM antibodies decay rapidly. Saliva can be used as an alternative biofluid for antibody testing due to detectable levels of spike protein-specific antibodies.
Researchers discovered that speech generates conical airflow that can travel up to 2 meters in 30 seconds, emphasizing the importance of time and distance in transmission. Saliva filaments form on the lips during consonant sounds, breaking into microscopic droplets that spread pathogens.
Scientists at Hokkaido University developed a saliva test that detects asymptomatic COVID-19 cases with high sensitivity and specificity. The study found that saliva samples can accurately identify infected individuals without symptoms, reducing the risk of viral transmission to healthcare workers.
A membrane-based invention can concentrate virus content from urine or saliva samples, allowing for early detection of COVID-19. The technique is promising for pregnancy testing as well, with a sample analysis time of just five minutes.
Researchers developed a saliva test to diagnose heart attacks, showing strong agreement with blood tests. The test provides results in 10 minutes, compared to at least one hour for standard blood tests, and has the potential to save lives.
The Forsyth Institute is working with the NIH's RADx initiative to develop and deploy accurate, rapid COVID-19 point-of-care tests using saliva samples. The institute brings its expertise in salivary diagnostics and has been at the forefront of salivary research for decades.
Research found that frequent use of antimicrobial drugs in early life shifts bacterial profiles in saliva, with azithromycin having the strongest effect on girls. The study also showed that AM use is associated with a decrease in Paludibacter and pathways related to amino acid degradations.
A new study by ARUP Laboratories and University of Utah Health found that self-collected saliva and deep nasal swabs are equally effective in detecting SARS-CoV-2, the virus causing COVID-19. This discovery has important implications for patients and providers, offering a less invasive testing option.
A new method uses conductive polymer spray ionization mass spectrometry and machine learning to detect changes in metabolites in saliva samples from 373 volunteers. The diagnostic accuracy of the method is reported at 86.7%, suggesting a potential point-of-care test for oral squamous cell carcinoma.
Researchers discovered that even a gentle breeze can propel saliva droplets up to 18 feet in just 5 seconds. This finding has significant implications for health and safety distance guidelines and the transmission of airborne diseases.
A UCF team is exploring a novel approach to reduce COVID-19 transmission by making saliva heavier and stickier using candy or corn starch. The goal is to create a simple cough drop that can help sneeze and cough particles fall rather than float in the air, reducing transmission distance.
A new non-invasive method of monitoring diabetes uses saliva as a more convenient and sustainable alternative to traditional blood glucose testing. The research, published in PLOS ONE, achieved an accuracy rate of 95.2% using infrared platform technology.
A new study found that chlorhexidine mouthwash significantly increases the abundance of lactate-producing bacteria, leading to lower salivary pH and buffering capacity. This may increase the risk of tooth damage. The research also showed reduced microbial diversity in the mouth.
A molecular marker in saliva is associated with childhood obesity emergence in preschool-aged Hispanic children. Salivary methylation of the NRF1 gene predicted childhood obesity three years later, even after controlling for maternal BMI and behavioral factors.
Brazilian researchers found a correlation between salivary uric acid levels and body fat percentages in teenagers, suggesting a reliable biomarker for early detection of chronic diseases. The study identified the level of uric acid in saliva as a good predictor of body fat percentage.
A novel noninvasive technique using acoustofluidics analyzes saliva for the presence of human papilloma virus-16 (HPV-16), associated with oropharyngeal cancers. The test detected OPC in 40% of patients tested and 80% of confirmed cases, offering early detection, risk assessment, and screening.
Researchers discovered that human saliva is more watery and contains distinct protein profiles compared to chimpanzees and gorillas. The differences are attributed to varying diets, with human saliva being effective at breaking down starch and fat.
A simple saliva test can identify recent spice use in five minutes, helping health professionals diagnose and treat patients. The test also provides information on the type of spice used and concentration.
Researchers have developed a pacifier-based biosensor that tracks real-time glucose levels in saliva, allowing for non-invasive monitoring of newborns. The device could help diagnose and treat diabetes in infants, providing an alternative to continuous glucose monitoring currently only available in hospitals.
Human saliva has distinct differences in protein content and structure compared to other primates, with a waterier consistency and higher amounts of enzymes and proteins involved in digestion and defense. These findings suggest that our diet and evolutionary adaptations played a significant role in shaping our unique saliva.
Scientists discover two compounds that can dry up tick saliva, reducing feeding and potentially limiting pathogen transmission. The treatment effectively kills ticks within 12 hours, a significant timeframe for pathogen transmission.
A hand-held device measures heart disease biomarkers from saliva to predict risk of heart disease, failure or heart attack. The technology has been validated in the lab with high accuracy and could help millions of potential victims take preventative steps.
A new technique developed by researchers allows for the creation of tastier low-fat potato chips by analyzing physical characteristics. The method, called in vitro oral processing, measures chip properties from first bite to swallow, enabling food scientists to link physical measurements with sensory perceptions.
A University at Buffalo study reveals that eating bitter foods like broccoli can alter the taste of those foods, and diet composition affects saliva proteins. Repeated exposure to these foods changes the sense of taste, making them more palatable.
Researchers at Boston University School of Medicine identified salivary microRNAs that differentiate people with alcohol dependence from healthy controls. The study uses machine learning to predict alcohol dependency with high accuracy, offering potential for early diagnosis and treatment.
Researchers have found that the structure, concentration and interactions of tannins in wine influence dryness perception. Trained sensory panelists perceived Cabernet Sauvignon as dryer due to its higher tannin content, while added tannins didn't change dryness perception in Pinot Noir.
New research from UNC School of Medicine reveals that tick bites can cause an allergic immune response to alpha-gal, a sugar found in most mammal blood except humans, leading to red meat allergy syndrome (AGS). This challenges previous theories and suggests the risk of each tick bite may be higher than anticipated.
Researchers have identified three biomarkers in saliva samples to detect mild cognitive impairment and Alzheimer's disease. The study uses metabolomics to analyze over 6,000 compounds, showing promising results for a potential clinical test.
Researchers at Brigham and Women's Hospital developed an automated, low-cost tool to predict ovulation using AI-powered fern pattern detection. The device achieved over 99% accuracy in detecting ovulation and non-ovulation, offering a potential solution for family planning and fertility monitoring.
A study found a correlation between oral cancer progression and the abundance of specific proteins in tumor tissue and saliva. The discovery offers a new parameter for predicting disease progression and may help guide treatment choices.
A study reveals that cats' tongues use fine structures called papillae to aid grooming. The papillae wick saliva from the mouth and deposit it onto fur, regulating body temperature.
New research reveals that breastmilk and saliva interact to regulate the oral microbiome of newborn babies, boosting innate immunity. The combination releases antibacterial compounds that inhibit the growth of both harmless and harmful microorganisms.
A recent study by scientists at the Institut Pasteur has demonstrated that tiger mosquitoes (Aedes albopictus) can transmit the yellow fever virus. The research found that the virus can adapt to this species, which is widely present in urban and forest areas, posing a major public health threat.
Salivary proteins could be part of a feedback loop that influences food taste and dietary choices. Researchers found that drinking bitter foods altered saliva protein composition, which corresponded to changes in sensory ratings.
A study found that ginger's 6-gingerol increases the enzyme sulfhydryl oxidase 1 in saliva, breaking down malodorous sulfur-containing compounds and reducing bad breath. Citric acid, on the other hand, makes people less sensitive to salt by increasing sodium ion content in saliva.
Researchers explored using saliva for early assessment of lung cancer and detection of stress hormones, enzyme levels, and developmental disease biomarkers. Saliva liquid biopsy shows promise in detecting circulating tumor DNA of lung cancer with high performance.
The symposium highlighted new discoveries about oral exRNA biology, providing insights into saliva's unique fraction of exogenous RNA. Researchers discussed leveraging salivary extracellular RNA to improve research and practice in the field of dental and oral health.
Researchers found that proteins in saliva reflect high blood sugar levels in young patients with type 1 diabetes, allowing for early prediction of complications. A potential new preventive treatment has been identified using gene database searching.
Researchers found that ultra-high-strength MRI releases high levels of mercury from amalgam fillings, but lower strength MRI does not cause significant leakage. The study suggests further research is needed to evaluate the relationship between high-field MRI and mercury release.
Researchers at Baylor College of Medicine found that mosquito saliva alone can trigger long-lasting immune responses in humanized mice, including activation of T helper cells and diverse cytokine levels. The study offers insights into developing effective strategies to prevent mosquito-borne diseases.
Researchers at Broad Institute of MIT and Harvard have developed a new tool that enables clinicians to quickly diagnose patient samples and track epidemics using CRISPR-based SHERLOCK. The platform can detect viruses directly in bodily fluids, eliminating the need for lab equipment and trained personnel.
Researchers found epigenetic changes in saliva linked to childhood trauma and autism spectrum disorder, suggesting saliva as a potential biomarker. The study aimed to identify early markers of abuse-related deaths and ASD diagnosis, providing insights into the impact of early life experiences on health outcomes.
Researchers discovered that blowflies use a unique mechanism called 'bubbling' to cool down, moving a droplet of saliva in and out of their mouths to promote evaporation. This behavior helps lower the insect's body temperature by up to 8°C below ambient temperature, with a significant impact on its flight muscles and brain.
New research finds that fungi in healthy adults' gut samples correspond to species present in saliva, foods, or experimental diets. These fungi pass through the GI tract as part of digestion rather than colonizing.
The symposium presented new discoveries about oral exRNA biology, including its use as a biomarker for diagnosing disease and tracking its progression. The study of salivary proteome and its diagnostic applications was funded by the National Institute of Dental and Craniofacial Research.
Researchers at Boston University School of Medicine discovered that histatin-5 in saliva stiffens ETEC pili, preventing infection. This finding opens up new avenues for prevention and treatment of enteric infectious diseases.
Researchers found that certain microRNAs in saliva can accurately identify concussions and predict symptom duration. The study's findings suggest that measuring microRNAs could lead to a more fact-based diagnosis and treatment of concussion patients, ultimately improving care and outcomes.
Pioneering UH researcher Chandra Mohan proposes a simpler salivary test to diagnose lupus, potentially replacing invasive blood tests. Saliva samples from people with SLE harbor antibodies and proteins that could be used as biomarkers for the disease.
A study found that people who can easily taste salt have differing amounts of salivary proteins than those who are less sensitive. This could lead to the development of more palatable low-sodium foods.
Researchers aim to detect synthetic opioids, heroin, and a heroin substitute in saliva samples from inmates, arrestees, and DUI suspects. This study could save time and money by using a single sample for multiple drug tests.
Researchers found that people exposed to more sandfly bites had higher anti-saliva IgG immune responses and a greater risk of developing cutaneous leishmaniasis. This study provides insights into the mechanisms governing resistance or susceptibility to Leishmania parasite transmission.