Researchers found that pairing leptin with a minor amount of exercise revived the hormone's ability to fight fat, preventing weight gain in obese rats. The study suggests that low-level exercise triggered a metabolic change that cleared the way for leptin to work effectively.
A study of 5,840 people found a connection between low birth weight, excessive weight gain during adolescence and young adulthood, and an increased risk of developing heart disease. Chronic inflammation, measured by C-reactive protein levels, may play a key role in this association.
A study of 36 freshmen at Auburn University found that students gained an average of 1.9 pounds during the first semester and 4.8 pounds for the entire freshman year, with some losing weight altogether.
A study published in JAMA found that individuals who received monthly tips from trained counselors regained less weight than those using a custom-built weight-loss Web site or self-directed approach. The average weight regain was 9 pounds for the counseling group, compared to 12 pounds for both the web site and self-directed groups.
Obese women should not be encouraged to gain at least 15 pounds during pregnancy, according to Saint Louis University obstetrician Raul Artal. Engaging in physical activity and proper diet can help prevent health issues like hypertension and diabetes.
Scientists at University College London have identified two cell proteins that relax the gut and help accommodate large meals. The P2Y1 and P2Y11 receptor proteins could provide a new approach to combatting weight gain by preventing stomach expansion.
Researchers found that rats given artificial sweetener saccharin consumed more calories, gained weight, and did not compensate later. The study suggests that breaking the connection between sweetness and high-calorie food can confuse the body's ability to regulate intake.
A study by Paul Williams found that quitting exercise can lead to significant weight gain, especially at lower intensity levels. Resuming exercise after an hiatus is often not enough to reverse the weight gain, highlighting the importance of consistent and year-round physical activity to maintain a healthy weight.
A weight control program has been shown to reduce weight gain and improve cholesterol levels in patients taking antipsychotic medication. The study found that participants who engaged in regular physical activity and healthy eating experienced significant improvements in their lipid profile and body mass index.
Researchers found that lipoic acid supplements reduced atherosclerotic lesion formation by 55% in mice, lowered triglycerides, and helped normalize metabolic processes. The supplements may be useful as a preventive mechanism before advanced cardiovascular disease develops.
A randomized controlled trial suggests that combining lifestyle intervention with metformin is the most effective treatment for antipsychotic-induced weight gain. Participants who received this combination therapy experienced significant reductions in body mass index, waist circumference, and insulin resistance. In contrast, those who ...
A University of Wisconsin-Madison study reveals a genetic basis for why high-carb diets lead to weight gain. The SCD-1 gene in the liver is responsible for synthesizing fatty acids, and when this gene is active, mice on high-carb diets store excess energy as fat.
A community-based weight control program, Girls Health Enrichment Multisite Studies (GEMS), demonstrated a significant reduction in the prevalence of obesity among 8-10 year old African-American girls for up to two years. The program's success was attributed to changes in dietary intake and education.
A new study by University of Michigan researchers found that fear of weight gain is a significant obstacle to quitting smoking for many women, who often have unrealistic body images and eating problems. Despite this, most weight-concerned smokers can be successful in kicking the habit with help.
A new analysis from Northwestern University found that consistently high levels of physical activity in young adulthood can stabilize body mass index (BMI) over 20 years. Participants who reported at least 30 minutes of vigorous activity a day gained 14 pounds less over 20 years than those with low activity levels.
A Mayo Clinic study found that modest weight gain in lean, healthy young adults impairs blood vessel function, but shedding the weight restores proper functioning. Visceral fat is a key predictor of this disorder, also known as endothelial dysfunction, which can lead to heart attacks and strokes.
Researchers at the University of Cincinnati have discovered a new molecular target that may help develop drugs to reduce fat transport in adipocytes and prevent obesity. Knocking out a specific cell receptor called LRP1 has been shown to decrease fat storage and weight gain in genetically altered mice.
Research suggests that weight gain throughout adulthood, rather than maintaining a stable weight, may increase the risk of breast cancer after menopause. Women who gained weight during certain life stages were more likely to develop breast cancer compared to those with stable weights.
A Saint Louis University study suggests severely obese women should lose weight during pregnancy, while obese women who are pregnant should gain less weight. Limiting weight gain reduces the risk of preeclampsia, cesarean delivery, and has babies with normal birth weights.
A study found that mothers who gained weight between their first and second pregnancies were more likely to have a baby boy. The researchers analyzed data from over 220,000 women and discovered a significant association between increased maternal weight gain and an increased male-to-female sex ratio in the second pregnancy.
A new study published in the Journal of Human Lactation has found that exclusively breastfed newborns tend to lose less weight than formula-fed infants, which may be at risk of early overfeeding. Supplemented breastfed infants had similar weight loss patterns to exclusively breastfed newborns.
A genetic metabolic defect in the liver can lead to obesity in some individuals, a study published in Metabolism reveals. The defect impairs the body's ability to burn fat, leading to increased hunger and overeating.
Researchers at Georgetown University Medical Center have found a mechanism to manipulate fat in targeted areas using simple chemical injections. This breakthrough could lead to better control of metabolic syndrome and revolutionize human cosmetic and reconstructive plastic surgery.
A family-based weight management program improved outcomes for overweight children compared to traditional weight counseling, reducing body fat and increasing insulin sensitivity. The study found significant differences in BMI, body weight, and cholesterol levels between the two groups after 12 months.
Researchers found that mice without CD38 were protected from high-fat diet-induced obesity and glucose intolerance. The study suggests that a CD38 deficiency has a protective effect against obesity, highlighting the importance of genes in regulating body weight.
A study by University of Virginia researchers found that mice lacking the Nocturnin gene were resistant to weight gain on a high-fat diet and had normal liver fat levels. This discovery may lead to new treatments for inhibiting obesity and its effects on health.
Researchers found that improving communication and patient involvement led to significant weight gain among Alzheimer's patients, who also displayed improved intellectual abilities. The study aimed to measure weight changes in patients with moderate and severe dementia.
A large-scale study found that calcium and vitamin D supplements can slow weight gain in postmenopausal women. The benefits are most pronounced in those who weren't already meeting the daily recommended amount of calcium.
A study of over 8,300 runners found that maintaining vigorous exercise helps prevent extreme weight gain, a significant risk factor for high blood pressure, diabetes, and other diseases. Regular running reduces waist circumference and hip size in women, while also combating age-related weight gain.
A synthetic drug activates PPAR-d, the master regulator of fat metabolism, making mice resistant to weight gain and increasing their endurance. This breakthrough could lead to a new approach in treating human metabolic syndrome, which includes obesity-related health issues.
Female ixodid ticks exhibit remarkable weight gain following mating, with some species increasing in size up to 100 times their original size. This phenomenon is linked to the tick's unique lifestyle and reproductive strategy, which involves prolonged feeding periods and specialized signals triggered by copulation.
A recent study published in Preventive Medicine found that frequent self-weighing is not associated with depression in women. The research suggests that daily weight monitoring can lead to lower BMI levels and less weight gain, making it a potentially beneficial practice for adults.
A study of 31 long-term diet studies found that only a small minority of participants achieved sustained weight loss, while the majority regained weight. Exercise was found to be a key factor in maintaining weight loss, and dieting may even lead to negative health effects.
A new study found that pregnant women who gain excessive or adequate weight are four times more likely to have an overweight child. The study suggests reevaluating current pregnancy weight guidelines, as excessive weight gain during pregnancy can influence child health and increase the risk of obesity.
Researchers found that overweight teens who lost weight engaged in significantly more moderate to vigorous physical activity (7.6 hours/week for females, 11.7 hours/week for males) and spent less time watching TV compared to those who gained or maintained weight. This study provides valuable insights into behaviors associated with succ...
The Stanford University School of Medicine study found that the Atkins diet was the most effective for weight loss among four popular diets. The women on the Atkins diet lost more weight and experienced greater improvements in cholesterol and blood pressure compared to those on other diets. The simplicity and high protein content of th...
A new study suggests that skipping breakfast and consuming frequent fast food lead to an increased risk of weight gain in adolescents as they enter adulthood. Researchers analyzed data from over 20,000 teens and found a significant increase in both behaviors and associated weight gain during this critical period.
A study published in Nicotine & Tobacco Research found that naltrexone significantly improved smoking cessation rates for women, with a 49% increase in success rates compared to men. The medication reduced cravings and withdrawal symptoms, leading to a higher likelihood of quitting smoking.
A study published in The Lancet found that weight gain during the interpregnancy period is strongly associated with major maternal and perinatal complications. Women who gained 3 or more BMI units were at increased risk of stillbirth, large-for-gestational-age births, and caesarean delivery.
A new study found that an increase in body mass index (BMI) between first and second pregnancies is associated with adverse outcomes, including maternal complications and perinatal complications. Women who gained a modest amount of weight between pregnancies experienced increased risks of gestational diabetes and stillbirth.
New research published by the American Physiological Society found that brains of rats bred to be lean are more sensitive to orexin A, a chemical that stimulates appetite and physical activity. This suggests a biological basis for being a couch potato, where fidgeting and other minor movements can burn calories and aid weight control.
A study found that TB patients underweight at diagnosis who gain less than 5% weight during the first two months of treatment have a significantly increased risk of disease relapse. This association holds even among those with abnormal chest x-rays and positive sputum cultures after 2 months of anti-tuberculosis treatment.
A new anti-obesity vaccine has shown promising results by slowing down weight gain and reducing body fat in animal models. The vaccine, targeting the hormone ghrelin, allowed rats to maintain normal eating habits while gaining less weight and accumulating less fat.
A recent study published in JAMA Network found that weight gain since early adulthood is associated with an increased risk of breast cancer in postmenopausal women. Women who gained 55 pounds or more after age 18 were at a 45% increased risk, while those who lost 22 pounds or more and maintained their weight had a 57% lower risk.
Researchers found that a single bout of overeating from supersizing a fast-food meal can result in significant hidden financial costs, including increased energy needs, medical care, and vehicle expenses. The study's findings suggest that these costs can outweigh the initial savings of upsizing a meal, making it a less affordable option.
A large study of 68,183 middle-aged women found that those who slept 5 hours or less per night were more likely to experience major weight gain and become obese over 16 years. The researchers didn't find a link between sleep duration and physical activity levels.
A study found that women in low-income food-insecure households are 50% more likely to be obese and gain at least 10 pounds in a year compared to those in fully secure households. Researchers propose modifying food assistance programs and nutrition education to address this issue.
Researchers found that women who gained more than 60 pounds during adulthood were almost twice as likely to have ductal type tumors and more than 1.5 times more likely to have lobular type cancers. The risk for metastatic disease increased with weight gain, particularly among those who gained over 60 pounds.
Researchers found that a patient's prepregnancy weight is the strongest predictor of birth weight in the next pregnancy. Dr. Robert Blaskiewicz advises overweight moms to lose weight after their first pregnancy and avoid gaining weight between pregnancies.
Scientists studying social stress in Syrian hamsters found that subordinates eat more and gain weight after being defeated by a dominant hamster. This model can help researchers understand human stress-induced obesity.
A newly discovered enzyme in the brain, CPT1c, plays a crucial role in managing hunger and satiety. Mice lacking this gene eat less but gain more weight on high-fat diets due to their brain's inability to regulate energy balance.
A new study provides evidence that consuming three servings of low-fat dairy foods per day can aid in weight loss and promote overall health. The research, consistent with the 2005 Dietary Guidelines for Americans, highlights the benefits of dairy consumption on body weight.
Researchers have identified a new target for obesity treatment by discovering a small molecule that activates the G protein-coupled receptor GPR119, leading to reduced food intake and weight gain in rats. The compound, PSN632408, also shows promise in improving lipid profiles and insulin sensitivity.
A study published in Pediatrics found that children who underwent surgery for obstructive sleep-disordered breathing (OSDB) due to enlarged adenoids experienced a significant increase in excess weight, averaging 13% over 12.6 months. This weight gain may be linked to reduced motor activity and poor sleep quality after the surgery.
A Rutgers University study found that college students experience average weight gain of seven pounds during their first year, primarily resulting from consuming excess calories. The researchers recommend adopting a balanced diet and increasing exercise to prevent weight gain and associated health risks.
Scientists studied mice lacking POMC gene to understand obesity and fat distribution. The research shows that cortisol levels are not the sole factor, but rather part of a chain of hormonal signals associated with obesity. Glucocorticoids were found to accelerate weight gain and diabetes in treated mice.
Researchers dispelled the myth that eating late at night causes weight gain. Female rhesus monkeys on a high-fat diet gained 5% more weight after having their ovaries removed, showing ovarian hormones play a role in weight balance. The study found no correlation between late-night eating and weight gain.
In a study published in Biology Letters, researchers found that male monkeys of two species experience a 10% weight gain when their mates are pregnant. This gain is likely due to hormonal changes, including increased prolactin and estrogen levels. The study's findings could provide insights into human fathering behavior and motivate me...
Researchers have discovered a new key area in the brain that responds to the fat hormone leptin, which plays a crucial role in resisting high-fat-diet-induced obesity. The ventromedial hypothalamus (VMH) region, previously thought to only be involved in appetite regulation, was found to also respond to leptin and is essential for maint...
The Women's Health Initiative Dietary Modification Trial found that a low-fat, high-carbohydrate diet did not result in weight gain among postmenopausal women. Instead, participants lost about 5 pounds initially and weighed less than the control group after 9 years.