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Do lifetime body weight patterns affect kidney cancer risk?

New research suggests that maintaining a healthy weight throughout life and losing weight later in life may reduce the risk of kidney cancer. Higher BMI at various ages across adulthood was associated with increased risks of developing different types of kidney cancer, including renal cell carcinoma, papillary RCC, and chromophobe RCC.

SourceWiley·JournalCancer·DateMar 24, 2025

Weight loss protects – even when weight is regained

A Swedish study of over 1,300 participants found that losing a significant amount of weight still offers protection against health issues like cancer and cardiovascular disease, even if some weight is regained. However, regaining weight can increase the risk of microvascular disease and other health problems.

SourceUniversity of Gothenburg·JournalThe Lancet Regional Health - Europe·TypeObservational study·DateMar 21, 2025

Weight loss increases risk of death for obese adults

A recent study published in Heart journal found that extreme weight fluctuations significantly increase the risk of death among obese individuals with cardiovascular disease. Both weight loss and gain above 10kg raise mortality risk, highlighting the importance of maintaining a stable weight even within the obese range.

SourceAnglia Ruskin University·JournalHeart·TypeData/statistical analysis·DateMar 12, 2025

Study finds tonsil removal not linked to undesirable weight gain, contrary to popular belief

Researchers found no correlation between adenotonsillectomies and undesirable weight gain in children with mild sleep-disordered breathing. The study used data from a clinical trial involving 458 children and showed that adenotonsillectomy improved symptoms, blood pressure, and quality of life but not primary neurodevelopmental outcomes.

SourceMichigan Medicine - University of Michigan·JournalJAMA Otolaryngology–Head & Neck Surgery·TypeRandomized controlled/clinical trial·DateDec 11, 2024

Anti-obesity drugs, lifestyle interventions show cardiovascular benefits beyond weight loss

Studies published in JACC found that anti-obesity drugs such as tirzepatide and semaglutide improved cardiac structure and function, as well as reduced cardiac risk biomarkers with lifestyle interventions. These findings suggest that these treatments may have a transformative impact on cardiovascular health beyond weight loss.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateNov 18, 2024

A mother’s health problems pose a risk to her children

A recent study found that children born to mothers with polycystic ovary syndrome (PCOS) are at a higher risk of lower birth weight, shorter stature, and smaller head circumference. The researchers believe that the placenta's inability to meet the baby's demands due to PCOS-related hormonal imbalances may be the cause.

SourceNorwegian University of Science and Technology·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateNov 5, 2024

Feeding practices play a central role in infants’ rapid weight gain, UNC Greensboro researchers find

A UNC Greensboro study of 299 women and their infants found that obesogenic feeding practices, such as watching TV while feeding or formula-feeding, are strongly correlated with rapid infant weight gain. The researchers also found that mothers' prenatal psychological risk increases the likelihood they will engage in these unhealthy pra...

SourceUniversity of North Carolina at Greensboro·JournalPediatric Obesity·TypeObservational study·DateOct 24, 2024

New drug approach could underpin future weight loss therapies, study indicates

A new study suggests that a hydrogen sulfide-generating molecule targeting mitochondria can significantly slow weight gain and reduce liver fat accumulation in mice. The treatment, AP39, inhibits key metabolic pathways associated with obesity and inflammation, offering a promising new option for treating metabolic diseases.

SourceUniversity of Exeter·JournalPharmacological Research·TypeExperimental study·DateOct 10, 2024

Obese children are more likely to develop skin conditions related to the immune system

A large-scale study investigated the relationship between childhood obesity and immune-mediated skin diseases (IMSDs), such as atopic dermatitis and psoriasis. The study found that obese children were more likely to develop these conditions, with changes in body weight affecting their risk of developing these diseases.

SourceElsevier·JournalJournal of Investigative Dermatology·TypeData/statistical analysis·DateAug 21, 2024

Obesity-induced inflammation increases the secretion of extracellular vesicles from adipose tissue

Research from the University of Eastern Finland found that obesity-induced inflammation increases the secretion of extracellular vesicles from human adipocytes, which may contribute to the detrimental health effects of obesity. Visceral adipose tissue secretes more extracellular vesicles than subcutaneous adipose tissue.

SourceUniversity of Eastern Finland·JournalJournal of Translational Medicine·DateAug 19, 2024

When you eat may impact your overall health, nutrition experts say

A special issue of the Journal of the Academy of Nutrition and Dietetics explores the effects of various fasting regimens on body weight, cardiometabolic disease risk, and sleep. The study found that time-restricted eating can result in clinically meaningful weight loss and reduction in liver enzymes in adolescents with type 2 diabetes.

SourceElsevier·JournalJournal of the Academy of Nutrition and Dietetics·TypeExperimental study·DateJul 18, 2024

Weight gain in young and middle-aged adults is linked to poor heart health in older age

A major study found that people who gained excess weight from their 20s onwards had less healthy hearts by the time they were in their 60s. The researchers linked weight gain in young and middle-aged adults to enlarged hearts that pump blood less well, over and above the effect of being overweight in later years.

SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·TypeObservational study·DateJul 16, 2024

Medication choice may affect weight gain when initiating antidepressant treatment

A study of over 183,000 adults found that certain antidepressants can cause significant weight gain or loss, while others have little to no effect. Bupropion was consistently associated with the least weight gain among 8 first-line antidepressants, which may impact medication adherence and patient treatment decisions.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeNews article·DateJul 1, 2024

Myths about intermittent fasting, debunked

Research debunks four common myths about intermittent fasting: it does not lead to a poor diet, cause eating disorders, excessive lean muscle mass loss, or affect sex hormones. Studies show both types of intermittent fasting (alternate-day and time-restricted) are safe despite popular misconceptions.

SourceUniversity of Illinois Chicago·JournalNature Reviews Endocrinology·DateJun 24, 2024

Research shows GLP-1 receptor agonist drugs are effective but come with complex concerns

Research shows that GLP-1 receptor agonist drugs are highly effective for weight management and Type 2 diabetes treatment, but they come with complex considerations such as dosages, side effects, and comparisons between specific drugs. Experts caution against overusing these drugs or viewing them as a universal cure-all for obesity.

SourceUniversity of Chicago Medical Center·JournalHealth Affairs Scholar·DateJun 5, 2024

Intermittent fasting shows promise in improving gut health, weight management

A new study highlights the benefits of intermittent fasting and protein-pacing on gut health, weight loss, and metabolic responses. Participants showed improved diversity of the gut microbiota, decreased symptoms of gastrointestinal problems, and increased beneficial microbes linked to a lean body type.

SourceArizona State University·JournalNature Communications·TypeRandomized controlled/clinical trial·DateMay 28, 2024