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Once-weekly exenatide injection improves blood sugar control more than daily oral sitagliptin or pioglitazone and induces more weight loss (DURATION-2 study)

The DURATION-2 study found that once-weekly exenatide improved HbA1c levels by 1.5% compared to 0.9% for sitagliptin and 1.2% for pioglitazone, with significant weight loss in the exenatide group. The findings suggest that exenatide should be considered as an adjunct to metformin for improving glucose control and weight loss.

SourceThe Lancet_DELETED·JournalThe Lancet·DateJun 26, 2010

Once weekly exenatide for type 2 diabetes is more convenient and induces better blood sugar control and more weight loss, than standard second-line treatment of daily insulin glargine

A 26-week randomized study found that once-weekly exenatide significantly improved blood sugar control, inducing a mean weight loss of 2.6kg per patient, compared to insulin glargine's lesser effect and mean weight gain of 1.4kg. The treatment also had lower rates of hypoglycemia and a progressive decrease in bodyweight.

SourceThe Lancet_DELETED·JournalThe Lancet·DateJun 24, 2010

Body-image distortion predicts onset of unsafe weight-loss behaviors

Research by University of Illinois expert Janet Liechty finds that body-image distortion is a better screening tool to identify non-overweight girls at risk for unsafe weight-loss practices. Girls with distorted body-image are more likely to resort to dieting and extreme methods, increasing their risk of continued use.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalJournal of Adolescent Health·DateJun 17, 2010

A doctor's referral for better fitness

Research by NiCole Keith highlights the need for physicians to consider physical activity levels a vital sign, similar to height and blood pressure. Regular discussions about exercise habits can help reduce stigma and promote healthy behaviors, leading to better weight management outcomes.

Asking 'why' instead of 'how' helps consumers achieve goals of saving money or losing weight

A new study found that focusing on the abstract reasons behind a goal leads to better decision-making and a higher likelihood of taking advantage of unexpected opportunities. By adopting a mindset that considers 'why' rather than just 'how', individuals can overcome obstacles and achieve their objectives more effectively.

SourceUniversity of Chicago Press Journals·JournalJournal of Consumer Research·DateMay 18, 2010

Shape up the quick way

A new study published in the International Journal of Behavioral Medicine found that losing weight quickly, rather than gradually, is associated with larger long-term weight losses and reduced risk of weight regain. Women who lost weight at a faster rate were more likely to achieve clinically significant weight loss and maintain their ...

SourceSpringer·JournalInternational Journal of Behavioral Medicine·DateMay 6, 2010

Managing the emotions behind eating

Researchers at Temple University's Center for Obesity Research are developing a new weight loss treatment that incorporates skills to address emotional eating. The program helps participants recognize and manage emotional triggers, such as boredom, frustration, or sadness, to break the cycle of overeating.

The remarkable effects of fat loss on the immune system

A recent study published in the Journal of Clinical Endocrinology Metabolism found that modest weight loss can reverse many of the damaging changes seen in immune cells of obese people. This reversal is achieved through an 80% reduction of pro-inflammatory T-helper cells and reduced activation of other circulating immune cells.

SourceResearch Australia·JournalThe Journal of Clinical Endocrinology & Metabolism·DateApr 19, 2010

Weight loss diets significantly reverse arterial clogging -- Ben-Gurion University study

A two-year study led by Ben-Gurion University researchers found that moderate weight loss significantly reverses carotid artery atherosclerosis, reducing the risk of strokes and heart attacks. The study compared low-carbohydrate, low-fat and Mediterranean diets, showing improved results for those with greater weight loss.

Study examines outcomes after bariatric surgery revisions

A study of 56 patients who underwent revisional bariatric surgery found a higher risk of complications compared to the initial procedure. Patients experienced significant weight loss and resolution of nutritional complications, but also faced serious issues like internal leakage and pneumonia.

SourceJAMA Network·JournalArchives of Surgery·DateFeb 15, 2010

New research identifies modifiable risk factors for heart disease

Emerging research reveals that post-menopausal women experience adverse changes in lipid profiles around the time of their final menstrual period, independent of age. Conversely, quitting smoking before or after a heart attack significantly improves long-term survival rates, with reductions comparable to those from lifestyle changes an...

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateDec 11, 2009

Investigators identify successful weight control strategies for adolescents

A new study published in the Journal of the American Dietetic Association found that adolescents who successfully lost weight reported using six or more healthy weight control behaviors, such as eating more fruits and vegetables and exercising regularly. In contrast, those who did not lose weight relied less on structured behavior stra...

SourceElsevier Health Sciences·JournalJournal of the American Dietetic Association·DateDec 1, 2009

Mood improves on low-fat, but not low-carb, diet plan

A one-year study found that participants on a low-fat diet experienced improved mood and well-being compared to those on a high-fat, low-carbohydrate diet. The study suggests that the low-carb diet may have detrimental effects on mood due to its structured nature and potential social challenges.

SourceJAMA Network·JournalArchives of Internal Medicine·DateNov 9, 2009