Research on weight loss and its health effects. Covers GLP-1 injections, companion digital programs, pregnancy guidelines, and asthma benefits.
A meta-analysis of 10 randomized clinical trials found that topiramate-treated patients lost 11.8 pounds more on average than placebo group members, with a higher success rate for weight loss over 28 weeks.
Participants lost similar weight and body fat, but the online group reported greater gains in behaviors promoting healthy lifestyles. They also showed increased confidence in physical activity, even in challenging situations.
Researchers at Johns Hopkins Medicine found that low-carb diets with higher fat content do not pose immediate risks to vascular health. Obese individuals who followed a low-carb diet showed no adverse changes in key measures of arterial health.
A year-long study of 439 overweight-to-obese postmenopausal women found that losing more than 15% of their body weight significantly increases circulating vitamin D levels. This effect is independent of dietary intake and is not linear, with more substantial increases found in those who lose greater amounts of weight.
A new mouse study has found that maintaining body fat rather than losing it can lead to longer lifespan in mice. The findings contradict the widely held view that weight loss is essential for extending life, suggesting that individuals with difficulty losing weight may benefit from dietary restriction more.
The study found that participants lost an average of 5.5% of their body mass, reduced waist circumference by 5.15%, and increased effort capacity by 15%. The program also showed a decrease in bad cholesterol and increase in good cholesterol.
Researchers found that bariatric surgery significantly improved glycemic control in obese patients with type 2 diabetes, even before significant weight loss occurred. The study suggests that biochemical and hormonal changes related to branched-chain amino acids may play a key role in this improvement.
A randomized trial found that overweight postmenopausal women who combined a low-fat, low-calorie diet with regular aerobic exercise shed nearly 11 percent of their starting weight. This study suggests that combining diet and exercise is more effective for weight loss than either method alone.
A study by Kent State University researcher John Gunstad found that bariatric surgery patients showed improved memory function 12 weeks after their operations. The researchers tested 150 participants and discovered a link between weight loss and enhanced cognitive abilities.
In a one-year clinical trial, an investigational combination of drugs achieved unprecedented weight loss of up to 10 percent in obese individuals. The study found significant reductions in blood pressure, hemoglobin A1C, and inflammatory markers, as well as improvements in cholesterol and triglycerides.
A new two-drug combination of phentermine and topiramate achieves more than double the weight loss of orlistat and compares favorably with emerging drugs. The treatment also improves blood pressure, lipids, glycaemia, and inflammatory markers.
Researchers found that eating high amounts of protein made men who were trying to lose weight feel fuller throughout the day. The study also showed that larger meals led to reductions in appetite and feelings of fullness, contrary to the common trend of eating smaller, more frequent meals.
Researchers found that increasing protein to 25% of total calories helps reduce late-night desires to eat and increases feelings of fullness. Lean cuts of pork are a high-protein food option that can be easily incorporated into daily meals.
A study published in The New England Journal of Medicine found that combining diet and exercise improves physical performance by 21% in obese seniors, compared to 12% with weight loss alone and 15% with exercise alone. This combination also leads to significant improvements in strength, balance, and quality of life.
A Kaiser Permanente study found that people who slept 6-8 hours a night and reported lower stress levels lost more weight. The study involved nearly 500 participants who were trying to lose at least 10 pounds, and those with the lowest stress levels and adequate sleep were most likely to succeed.
A study of 82 patients found gastric banding resulted in a mean excess weight loss of 42.8%, with 40% experiencing major complications and nearly half requiring band removal, despite a 60.3% patient satisfaction rate.
A new study published in Clinical Obesity reveals that bariatric surgery can result in significant weight loss in severely obese adolescents. The existing evidence suggests that bariatric surgery in older children results in significant weight loss and improvements in comorbidities and quality of life.
A recent study found that lifestyle intervention, including nutrition and physical activity components, is necessary to maintain or lose weight. Clinicians can effectively prevent further weight gain by providing guidance on healthy habits, leading to improved health status in overweight patients.
A study found that gastric bypass surgery resulted in greater weight loss and improved resolution of type 2 diabetes compared to sleeve gastrectomy and lap-band surgery. Additionally, patients who underwent gastric bypass experienced better quality of life outcomes.
Using amphetamines like Benzedrine and Dexedrine may increase the risk of developing Parkinson's disease, according to a new study. The research, which followed 66,348 participants in northern California, found that those who used these drugs were nearly 60% more likely to develop the condition.
Researchers found that obese individuals with early-onset knee osteoarthritis who underwent weight loss via bariatric surgery experienced significant improvements in knee pain, stiffness, and physical function. Weight loss also improved quality of life and activities of daily living.
New research reveals obesity significantly impacts knee pain and function, but also improves with weight loss via bariatric surgery. Studies find increased risk of complications after hip and knee replacement surgery for super-obese patients, emphasizing the importance of weight management in treating knee arthritis.
A study found that African American men avoid doctor visits due to stress and lack of practical advice. The study suggests that physicians need to provide more support and resources to encourage men to follow medical recommendations.
A five-year study of 288 participants found that a combination of physical activity and weight loss improved mobility by 5-20% in older, obese adults. This counteracts the common belief that weight loss is unhealthy for older adults. Community-based programs can effectively provide seniors with poor mobility
A study of rhesus macaque monkeys found that oral contraceptives did not lead to significant weight gain or changes in food intake. In fact, obese monkeys lost weight and reduced body fat due to increased basal metabolic rate.
A new study published in Nutrition Journal found that consuming a large breakfast does not lead to increased calorie burn throughout the day. In fact, researchers discovered that individuals who had bigger breakfasts tended to consume fewer calories during lunch and dinner, offsetting the extra calories consumed at breakfast.
A deficiency in Toll-like receptor 2 leads to changes in gut bacteria resembling those of lean animals, suggesting a new way to manage weight and intestinal problems. This discovery builds on previous research demonstrating the protective effect of TLR2 deficiency against obesity.
A new study reveals that individuals with high leptin and low ghrelin levels are more likely to regain weight after dieting. Researchers analyzed the role of hormones in weight recovery and found a significant association between plasma levels of ghrelin, leptin, and insulin.
A recent study published in Obesity found that young adults with social connections to overweight friends and family members are more likely to have higher weight status. Researchers also discovered that these individuals who had close relationships with people trying to lose weight themselves were more motivated to do the same.
Women undergoing gastric band surgery reported significant improvements in urinary function and quality of life, while men experienced worsening erectile function. The study highlights the need for further research into the effects of weight loss surgery on urinary and sexual function.
A study published in the American Journal of Clinical Nutrition found no link between dairy consumption and increased risk of heart disease, stroke, or total mortality. The research also revealed that drinking three glasses of milk per day may lead to a reduced risk of cardiovascular disease.
A new study found that imposing higher taxes on sodas and sweetened drinks would generate significant revenue but result in only minor weight loss for most households. The tax's impact varies by household income, with middle-income groups experiencing the largest reductions in calories and weight.
Researchers at Harvard University project an estimated 42% of American adults will be obese by 2050, driven by the accelerating spread of obesity via social networks. The study found that non-obese individuals have a 2% chance of becoming obese annually, which increases with each obese social contact.
Two clinical trials show lifestyle interventions, including physical activity and structured weight loss programs, can result in significant weight loss. The studies found that intensive lifestyle interventions using a behavior-based approach can lead to clinically significant weight loss and improvements in cardiometabolic risk factors.
A study by Kerri N. Boutelle found that parent-only groups are a viable method for childhood obesity treatment, achieving similar results in child weight loss and other outcomes. The approach is more cost-effective and potentially easier for families, with further research planned.
Studies found that obese individuals have impaired autonomic function, leading to overeating. Obestatin levels were also linked to weight loss after bariatric surgery. Researchers hope to pursue obestatin as a potential indicator of surgery efficacy.
Researchers at the University of Colorado Anschutz Medical Campus found a nonprofit weight loss program to be effective in reducing and maintaining weight loss. The study followed thousands of people enrolled in TOPS for three years, with participants losing five to seven percent of their body weight and keeping it off.
A 12-week study of 86 overweight participants found that all three groups lost weight when consuming five to seven servings of potatoes per week. The results suggest that potatoes, when prepared in a healthy manner, do not contribute to weight gain and can be part of a weight loss program.
Two clinical trials show that intensive lifestyle interventions with diet, physical activity, and behavioral support can result in significant weight loss and improvements in cardiometabolic risk factors. The studies found that weight loss was more pronounced in the first six months, but similar at 12 months, with reductions in waist c...
A randomized controlled trial found that a structured weight loss program with free prepared meals, combined with one-to-one counseling, resulted in significant weight loss (up to 16 pounds) for participants. The program was maintained at two-year follow-up, suggesting long-term effectiveness.
A recent study published in Annals of Internal Medicine found that sleep loss limits fat loss. When dieters got adequate sleep, they lost more than half of their weight as fat, but when they cut back on sleep, only one-fourth of their weight loss came from fat.
Researchers at the University of Gothenburg developed a new equation to calculate energy requirements for underweight COPD patients, leading to more accurate nutritional approaches. The study found that this method can help patients stop losing weight and even gain weight.
A study by Duke University Medical Center found that doctors' communication styles significantly impact patients' weight loss success. Physicians who used a more motivational and empathic approach helped patients lose an average of 3.5 pounds, while those using a judgmental style saw little change.
Researchers discovered that Maf protein promotes osteoblast differentiation in mice, reducing bone formation and increasing fat cell generation with age. Additionally, studies found defective immune cells in patients with type 1 diabetes and suggested these cells could be a viable target for treatment.
Researchers at the University of Missouri found that resistance training during weight regain can maintain health gains, including reduced risks for diabetes and heart disease. Participants who performed supervised resistance training three times a week maintained improvements in cardiorespiratory fitness and strength.
Researchers found that participants who consumed the most milk products lost more weight on average than those with low or no milk consumption. Higher blood levels of vitamin D also predicted successful weight loss.
Researchers found that bariatric surgery significantly improves lipoprotein profiles in women within a year, reducing the risk of cardiovascular disease. Significant weight loss also leads to improvements in glucose homeostasis and lower mortality rates.
Reading food labels can improve weight loss chances for middle-aged Americans, with women and overweight/obese individuals seeing better success rates. The analysis also highlights the value of standardized nutrition facts on packaged foods and calls for posting nutritional information in restaurants and vending machines.
A new study found that higher baseline leptin and lower ghrelin plasma levels before dieting may predict weight regain in individuals. The research suggests that personalized weight-loss programs targeting appetite hormones could improve long-term success rates.
A new study published in the Journal of Consumer Affairs suggests that observing food labels and exercising regularly can lead to significant weight loss. The research found that women between the ages of 37-50 are more likely to read food labels, which increases their chances of losing weight.
Only one in six Americans who have ever been overweight or obese successfully maintains their weight loss, according to a new study. The researchers found that women, adults aged 75-84, and non-Hispanic whites were more likely to achieve long-term weight management.
Researchers have identified a critical regulatory switch in mesenchymal stem cell lineage allocation, which could lead to the development of new treatments for obesity and osteoporosis. The 'Sprouty' protein has been shown to regulate body fat and bone mass, with potential applications for weight loss and bone density improvement.
A new study found that the magnitude of loyalty reward programs affects consumers' perceptions of their progress. Smaller step-sizes elicit strikingly different reactions, with those closer to the reward feeling they have made more progress.
A new clinical trial confirms that drinking two 8-ounce glasses of water before meals helps people shed more pounds than those who do not drink water. The study found that water drinkers lost about 15.5 pounds over 12 weeks, while non-water drinkers lost about 11 pounds.
A study examines the impact of energy drink consumption on athletic performance and body composition, finding that caffeine is a key contributor to performance enhancement, while weight loss benefits are uncertain and may be linked to diminishing returns.
A pilot study found that reducing musculoskeletal pain by 20-30% is a key motivator for weight loss. The study, published in the journal Work, suggests that immediate health benefits can inspire overweight individuals to shed extra weight and commit to keeping it off.
A combination treatment of naltrexone and bupropion, along with diet and exercise, has been shown to reduce body weight by 5% or more in people with obesity. The study found that patients who received the treatment experienced significant weight loss, with those in the highest dosage group losing up to 6.1kg over 56 weeks.
A Kaiser Permanente Center for Health Research study found that participants who logged on to an interactive weight management website consistently maintained the most weight loss. Those who used the site at least once a month for two-and-a-half years kept off an average of nine pounds of their original weight loss.
Researchers found that obese people preferred public health interventions perceived as non-judgmental and empowering. Participants were less likely to view stigmatizing or shaming approaches as effective. Non-commercial techniques, such as personalised care planning and long-term support systems, were also supported.
A six-month weight loss intervention program improved flushing symptoms in overweight and obese women with menopause-related hot flushes. The study found that decreases in weight, BMI, and abdominal circumference were associated with improvements in self-reported hot flushes.