Articles tagged with Weight Loss
A 12-week study found that intermittent fasting, especially time-restricted eating, leads to greater weight loss and reduced abdominal subcutaneous fat compared to a nutrition education programme. This study suggests that this strategy can be an effective method for improving cardiovascular health in people with obesity problems.
A systematic review of randomized controlled trials found GLP-1 RAs and co-agonists to be effective for weight loss in adults with obesity, including promising options not yet FDA-approved. The study also showed similar safety profiles across agents, with mild gastrointestinal side effects being the most common.
A recent survey found that nearly half of U.S. adults plan to start a new diet in 2025, with the most common diets being low-calorie and low-carbohydrate options. However, plant-based diets have been shown to be effective for weight loss without restricting or counting calories, and also reduce the risk of obesity-related diseases.
Engaging in 30 minutes of aerobic exercise per week modestly reduces body weight, waist circumference, and body fat measures. Aerobic training exceeding 150 minutes per week may be needed for clinically important reductions.
A study published in PLOS Biology found that individuals with and without obesity prefer high-calorie foods, regardless of their taste or texture. The researchers used a large group of healthy volunteers to compare food preferences among three groups: individuals with obesity, post-bariatric surgery patients, and non-obese controls.
A cross-sectional study found substantial projected annual savings from weight loss among U.S. adults with obesity, particularly for Medicare and employer-based insurance. The estimated reduction in healthcare spending is substantial, offering a potential benefit for individuals with obesity.
A new type of gastric balloon has been designed to help people lose weight by making them feel too full to overeat. The balloon can be inflated and deflated as needed, and animal studies have shown that it can reduce food intake by 60 percent before meals.
A new study led by Weill Cornell Medicine found that tirzepatide reduced the risk of diabetes in obese and prediabetic patients by more than 90% after 176 weeks. The treatment also showed significant weight loss and improved blood sugar control.
A cohort study found that nearly half of participants who consumed alcohol at baseline decreased their alcohol use after initiating anti-obesity medication treatment. The medications, such as naltrexone and glucagon-like peptide-1 receptor agonists (GLP-1 RAs), may have properties that lead to reduced cravings for alcohol.
A systematic review of 18 randomized controlled trials found that drinking enough water can help with weight loss and prevent kidney stones. Drinking eight cups a day significantly decreased the likelihood of getting another kidney stone, while six cups a day helped adults lose weight.
A study estimates that approximately one-third of eligible US adults without diabetes were excluded from clinical trials supporting GLP-1 and GLP-1/GIP medications. The FDA should consider updating labeling to advise caution on generalizing these medications' safety and effectiveness to excluded populations.
A new study finds that replacing meat and dairy products with plant-based foods leads to a 92% reduction in hot flashes in postmenopausal women. The study also shows weight loss in both healthy and unhealthy plant-based diets, suggesting even 'unhealthy' plant-based foods can be beneficial.
A study of U.S. adults on anti-obesity medications found that 25% reported wasting more food since taking the drugs, while changes in diet and eating habits appeared to offset some of this waste, particularly among those who consumed more vegetables.
Research suggests that lifestyle modifications and metformin do not improve atrial fibrillation (AFib) burden or progression when compared to standard care. In contrast, weight loss and exercise resulted in decreased AFib symptoms in patients with the condition.
The study aims to confirm initial findings suggesting that increased step counts correlate with improved health indicators, such as reduced body fat and lower insulin levels. By establishing a model, the team hopes to provide healthcare professionals with a tool to recommend tailored walking goals for their patients.
Studies published in JACC found that anti-obesity drugs such as tirzepatide and semaglutide improved cardiac structure and function, as well as reduced cardiac risk biomarkers with lifestyle interventions. These findings suggest that these treatments may have a transformative impact on cardiovascular health beyond weight loss.
The international SUMMIT trial found tirzepatide lowered the risk of worsening heart failure events and cardiovascular death in obese adults with preserved ejection fraction. Participants experienced improved health status, physical function, and exercise tolerance compared to placebo.
Scientists have discovered a new weight loss drug target that increases calorie-burning and lowers appetite without causing nausea. The discovery could lead to a new therapy for millions of people with obesity and type 2 diabetes.
A study by the University of Gothenburg found that unclear procedures and distribution of responsibilities among healthcare workers can lead to poor oral health in older adults in nursing homes. The researchers suggest that a more structured process can promote communication and awareness of good oral health practices.
A team of researchers has discovered a previously unknown metabolic pathway involving beta-hydroxybutyrate (BHB), a key ketone body. This finding suggests that ketones have additional roles in the body's metabolic landscape, potentially influencing appetite suppression and weight regulation under ketosis conditions.
A systematic review found that weight-loss interventions were associated with improvements in some polycystic ovary syndrome (PCOS) symptoms, including improved menstrual frequency. The interventions also showed a clinically significant improvement in metabolic markers and hormonal balance.
A study of 260 teens who underwent bariatric surgery at age 13-19 found that over half demonstrated sustained weight loss and resolution of conditions like type 2 diabetes. After 10 years, 55% of participants with type 2 diabetes remained in remission.
A study found that increasing ketones through a keto diet or supplements can change menstrual frequency and intensity in pre-menopausal women. The research suggests that the presence of ketones, rather than weight loss, may regulate women's health.
Medically induced weight loss with GLP-1 receptor agonists can lead to substantial muscle loss, compromising physical strength and immune function. The authors emphasize the need for a multimodal approach combining medication with exercise and nutritional interventions to preserve muscle mass.
A recent study found that the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) as anti-obesity medications more than doubled from 2022 to 2023, while rates of metabolic bariatric surgery dropped by one quarter. This shift in treatment options has implications for access to comprehensive multidisciplinary care for obesity.
A study conducted by Hiddo L. Heerspink at the University Medical Center Groningen found that Ozempic reduced protein in urine by 52% and decreased kidney inflammation by 30%, as well as lowering blood pressure and reducing a key measure of heart failure
Two studies found that bariatric surgery is more cost-effective in the long term compared to GLP-1 RA weight loss drugs alone. Combining both treatments is even more cost-effective. The use of GLP-1 RA before surgery appears safe and may be a novel approach to treating obesity.
The EAT2 study, led by Dr. Ursula White, investigates the lasting health effects of short-term weight gain and loss on fat tissue and overall health. Participants will undergo a dietary intervention program followed by an eight-week weight loss treatment.
A systematic review and meta-analysis found that weight-loss surgery reduces pancreatic cancer risk among individuals with obesity by 44%, and among those with both obesity and type 2 diabetes by 79%. The study suggests that metabolic-bariatric surgery may play a crucial role in reducing the risk of pancreatic cancer.
A recent study by The Jackson Laboratory reveals that reducing calorie intake can significantly extend the lifespan of mice, with the most robust animals living the longest. However, the researchers found that losing weight on these diets had a negative impact on lifespan in humans.
A recent study discovered 14 'skinny genes' associated with significant weight loss in response to regular exercise. Participants who carried more of these genes lost up to 5kg during an eight-week period. Exercise was found to be crucial for unlocking the full potential of these genes, emphasizing the importance of lifestyle changes.
A new study from the University of Waterloo suggests that men and women should eat different breakfasts to lose weight. The research found that men's metabolisms respond better to high-carbohydrate meals after fasting, while women are better served by higher-fat meals.
A randomized controlled trial found that time-restricted eating (TRE) led to greater improvements in glucose control, weight loss, and fat reduction compared to standard nutrition counseling in adults with metabolic syndrome. TRE resulted in a lower risk of muscle mass loss during weight loss.
A new study finds that preventive health technologies can support healthy routines but also lead to compulsive usage, ultimately harming users. Consumers' experiences with these technologies vary, from increased engagement to reduced interest and obsessive behavior.
A new study demonstrates the potential of semaglutide in treating hidradenitis suppurative (HS) in people with obesity. The results show marked improvements in patient outcomes across several key measures, including reduced flare frequency, improved quality of life, and better glycaemic control.
A new study found that up to 10 million people in the US could qualify for Medicare-covered semaglutide injections, depending on their level of cardiovascular risk. Those with higher risk scores would be eligible for full or partial coverage, potentially expanding access to this life-saving medication.
A technology-assisted health coaching intervention called Goals for Eating and Moving (GEM) was tested in a cluster-randomized controlled trial involving 19 primary care teams. The study found that patients receiving the GEM intervention did not show significant weight loss compared to those receiving enhanced usual care, highlighting ...
A new study from Lund University found that a starch and sucrose-reduced diet is as effective in reducing IBS symptoms as the current recommended FODMAP diet. The study showed significant improvements in 75-80% of patients, with greater weight loss and reduced sugar cravings in the reduction group.
A study found that every 1% decrease in BMI leads to a 4% reduction in cardiovascular risk. Blood sugar control also lowers the risk of chronic kidney disease independently of weight change.
Two studies found breastfeeding after breast cancer diagnosis is safe and feasible for young patients with specific genetic variations, as well as hormone receptor-positive breast cancer survivors. A third study shows a telephone-based coaching program can significantly increase physical activity in overweight patients, potentially imp...
A retrospective cohort study of 3,389 patients with obesity found that semaglutide and liraglutide were associated with significant weight reduction at 1 year. The study suggests that persistent medication coverage, dosage, treatment indication, and patient sex are important factors in determining weight loss outcomes.
A Cleveland Clinic study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide. The study found that medication's active agent, dosage, treatment indication, and persistence with the medication were associated with weight change.
Researchers found that semaglutide and tirzepatide led to significant weight loss (9.1% and 21.4%, respectively) and improved blood sugar control in patients with type 1 diabetes. Weight loss was associated with reduced insulin dose, indicating improved insulin resistance.
A study by the University of Gothenburg found that only 3% of lifestyle advice recommendations have positive effects in practice. The researchers suggest alternative community-based interventions for improving public health. The new guideline aims to help policymakers evaluate the effectiveness of such interventions.
The SURPASS-4 trial found that tirzepatide improved blood glucose control and weight loss in adults with type 2 diabetes. Higher doses of tirzepatide and female patients were associated with better long-term outcomes, including reduced risk of cardiovascular events.
A phase 1 trial found that a new oral weight loss drug, Amycretin, resulted in significant weight loss of up to 13% over three months. The drug targets both amylin and glucagon-like peptide-1 (GLP-1) biology, leading to appetite regulation and reduced hunger.
Research highlights the positive impact of bariatric surgery on controlling high blood pressure in people with obesity. Combining data from 18 randomized controlled trials involving over 1,300 participants, studies found that weight-loss surgery consistently improved blood pressure control and lowered cardiovascular disease risk.
A post hoc analysis found semaglutide treatment did not increase the risk of developing depression or suicidal ideation and was associated with a small reduction in depressive symptoms. Monitoring for mental health concerns is essential for individuals with obesity to receive proper support and care.
A new Penn study analyzing data from over 3,500 participants in clinical trials found no increased risk of depressive symptoms, suicidal thoughts, or suicidal behavior among individuals taking semaglutide for weight management. The study's findings provide assurance that the medication does not increase the risk of mental health issues...
A recent study led by Brigham and Women's Hospital found that semaglutide reduced deaths from cardiovascular disease and infections, including COVID-19, in obese and overweight patients. The study involved over 17,000 participants and showed a 19% lower overall death rate compared to placebo.
New studies show semaglutide reduces all-cause death, CV death, and non-CV death in people with overweight or obesity and established cardiovascular disease. The medication also improves heart failure symptoms and physical limitations in those with obesity-related HFpEF, regardless of sex.
A study published in Annals of Internal Medicine found that approximately 61% of Medicare-eligible adults have a BMI of 27 or higher, making them eligible for semaglutide. However, the number of patients who will be eligible depends on how cardiovascular disease is defined, with narrow definitions resulting in only 3.6 million people b...
A KKH study found that exclusively breastfed women with high body mass index (BMI) lost more weight than those with a healthy BMI pre-pregnancy, with an average weight loss of 200 grammes. Women who practiced exclusive breastfeeding retained less postnatal weight compared to mixed feeding or formula feeding.
A new study estimates that 1 in 7 Medicare beneficiaries with elevated body mass index (BMI) may qualify for semaglutide, a popular weight loss medication. The study found that maximum annual costs to Medicare could exceed $10 billion if different definitions of cardiovascular risk are considered.
A large-scale study investigated the relationship between childhood obesity and immune-mediated skin diseases (IMSDs), such as atopic dermatitis and psoriasis. The study found that obese children were more likely to develop these conditions, with changes in body weight affecting their risk of developing these diseases.
A new study published in Frontiers in Nutrition found that a low-fat vegan diet reduces advanced glycation end-products (AGEs) by 73%, associated with an average weight loss of 13 pounds. The reduction came mainly from excluding meat, added fats, and dairy products.
A new study by UC Riverside demonstrates that calorie restriction does not significantly reduce voluntary exercise in mice. Researchers found that mice continued to run at similar levels regardless of the amount of food they ate, challenging the long-held belief that dieting drains workout energy. The study's findings have implications...
A new study by Charles Sturt University in Australia found that exposure to pro-anorexia content on TikTok leads to decreased body image satisfaction and increased internalization of beauty standards. Women who spend more time on the app are also more likely to experience disordered eating behaviors.
A new study published in Acta Paediatrica reports on the physical and psychological state of 19 children and 7 women who were released from Hamas captivity. The returnees suffered from various health complications, including gastrointestinal pathogens and infectious diseases, as well as trauma and poor hygiene-related issues.
The number of semaglutide prescriptions filled reached 2.6 million in 2023, with Wegovy accounting for most fills since its approval in June 2021. Most Wegovy fills were among commercially insured populations, despite the disproportionate burden of obesity in Medicaid and Medicare Part D.