Articles tagged with Weight Loss
A technology-assisted health coaching intervention called Goals for Eating and Moving (GEM) was tested in a cluster-randomized controlled trial involving 19 primary care teams. The study found that patients receiving the GEM intervention did not show significant weight loss compared to those receiving enhanced usual care, highlighting ...
A new study found that up to 10 million people in the US could qualify for Medicare-covered semaglutide injections, depending on their level of cardiovascular risk. Those with higher risk scores would be eligible for full or partial coverage, potentially expanding access to this life-saving medication.
A new study from Lund University found that a starch and sucrose-reduced diet is as effective in reducing IBS symptoms as the current recommended FODMAP diet. The study showed significant improvements in 75-80% of patients, with greater weight loss and reduced sugar cravings in the reduction group.
A study found that every 1% decrease in BMI leads to a 4% reduction in cardiovascular risk. Blood sugar control also lowers the risk of chronic kidney disease independently of weight change.
Two studies found breastfeeding after breast cancer diagnosis is safe and feasible for young patients with specific genetic variations, as well as hormone receptor-positive breast cancer survivors. A third study shows a telephone-based coaching program can significantly increase physical activity in overweight patients, potentially imp...
A retrospective cohort study of 3,389 patients with obesity found that semaglutide and liraglutide were associated with significant weight reduction at 1 year. The study suggests that persistent medication coverage, dosage, treatment indication, and patient sex are important factors in determining weight loss outcomes.
A Cleveland Clinic study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide. The study found that medication's active agent, dosage, treatment indication, and persistence with the medication were associated with weight change.
A study by the University of Gothenburg found that only 3% of lifestyle advice recommendations have positive effects in practice. The researchers suggest alternative community-based interventions for improving public health. The new guideline aims to help policymakers evaluate the effectiveness of such interventions.
Researchers found that semaglutide and tirzepatide led to significant weight loss (9.1% and 21.4%, respectively) and improved blood sugar control in patients with type 1 diabetes. Weight loss was associated with reduced insulin dose, indicating improved insulin resistance.
The SURPASS-4 trial found that tirzepatide improved blood glucose control and weight loss in adults with type 2 diabetes. Higher doses of tirzepatide and female patients were associated with better long-term outcomes, including reduced risk of cardiovascular events.
A phase 1 trial found that a new oral weight loss drug, Amycretin, resulted in significant weight loss of up to 13% over three months. The drug targets both amylin and glucagon-like peptide-1 (GLP-1) biology, leading to appetite regulation and reduced hunger.
Research highlights the positive impact of bariatric surgery on controlling high blood pressure in people with obesity. Combining data from 18 randomized controlled trials involving over 1,300 participants, studies found that weight-loss surgery consistently improved blood pressure control and lowered cardiovascular disease risk.
A new Penn study analyzing data from over 3,500 participants in clinical trials found no increased risk of depressive symptoms, suicidal thoughts, or suicidal behavior among individuals taking semaglutide for weight management. The study's findings provide assurance that the medication does not increase the risk of mental health issues...
A post hoc analysis found semaglutide treatment did not increase the risk of developing depression or suicidal ideation and was associated with a small reduction in depressive symptoms. Monitoring for mental health concerns is essential for individuals with obesity to receive proper support and care.
New studies show semaglutide reduces all-cause death, CV death, and non-CV death in people with overweight or obesity and established cardiovascular disease. The medication also improves heart failure symptoms and physical limitations in those with obesity-related HFpEF, regardless of sex.
A recent study led by Brigham and Women's Hospital found that semaglutide reduced deaths from cardiovascular disease and infections, including COVID-19, in obese and overweight patients. The study involved over 17,000 participants and showed a 19% lower overall death rate compared to placebo.
A KKH study found that exclusively breastfed women with high body mass index (BMI) lost more weight than those with a healthy BMI pre-pregnancy, with an average weight loss of 200 grammes. Women who practiced exclusive breastfeeding retained less postnatal weight compared to mixed feeding or formula feeding.
A new study estimates that 1 in 7 Medicare beneficiaries with elevated body mass index (BMI) may qualify for semaglutide, a popular weight loss medication. The study found that maximum annual costs to Medicare could exceed $10 billion if different definitions of cardiovascular risk are considered.
A study published in Annals of Internal Medicine found that approximately 61% of Medicare-eligible adults have a BMI of 27 or higher, making them eligible for semaglutide. However, the number of patients who will be eligible depends on how cardiovascular disease is defined, with narrow definitions resulting in only 3.6 million people b...
A large-scale study investigated the relationship between childhood obesity and immune-mediated skin diseases (IMSDs), such as atopic dermatitis and psoriasis. The study found that obese children were more likely to develop these conditions, with changes in body weight affecting their risk of developing these diseases.
A new study published in Frontiers in Nutrition found that a low-fat vegan diet reduces advanced glycation end-products (AGEs) by 73%, associated with an average weight loss of 13 pounds. The reduction came mainly from excluding meat, added fats, and dairy products.
A new study by UC Riverside demonstrates that calorie restriction does not significantly reduce voluntary exercise in mice. Researchers found that mice continued to run at similar levels regardless of the amount of food they ate, challenging the long-held belief that dieting drains workout energy. The study's findings have implications...
A new study by Charles Sturt University in Australia found that exposure to pro-anorexia content on TikTok leads to decreased body image satisfaction and increased internalization of beauty standards. Women who spend more time on the app are also more likely to experience disordered eating behaviors.
A new study published in Acta Paediatrica reports on the physical and psychological state of 19 children and 7 women who were released from Hamas captivity. The returnees suffered from various health complications, including gastrointestinal pathogens and infectious diseases, as well as trauma and poor hygiene-related issues.
Researchers found that Megamonas degrades intestinal myo-inositol, enhances lipid absorption, and contributes to obesity. The study suggests potential strategies for future obesity management by illustrating the bacterium's mechanism.
A USC study found that prescription fills for semaglutide increased by over 400% between 2021 and 2023, with most prescriptions going to privately insured patients. The study suggests that this may worsen disparities in diabetes and obesity outcomes among Medicaid and Medicare recipients.
The number of semaglutide prescriptions filled reached 2.6 million in 2023, with Wegovy accounting for most fills since its approval in June 2021. Most Wegovy fills were among commercially insured populations, despite the disproportionate burden of obesity in Medicaid and Medicare Part D.
Experts advocate for incorporating normalization of blood sugar regulation into diabetes prevention strategies. Studies show that weight loss-induced prediabetes remission can significantly reduce the risk of developing type 2 diabetes, especially when combined with lifestyle changes.
A recent study published in JAMA Pediatrics found that meal-replacement therapy paired with financial incentives resulted in a greater reduction in body mass index compared to MRT alone. The study enrolled 126 adolescents and found that the combination treatment led to a significant decrease in BMI and total body fat mass.
A special issue of the Journal of the Academy of Nutrition and Dietetics explores the effects of various fasting regimens on body weight, cardiometabolic disease risk, and sleep. The study found that time-restricted eating can result in clinically meaningful weight loss and reduction in liver enzymes in adolescents with type 2 diabetes.
Researchers analyzed fecal samples from fat cats undergoing different dietary changes and found striking similarities to human studies, particularly in the presence of short-chain fatty acids. The study suggests that feline gut microbiome shifts may correlate with metabolic outcomes and provide valuable insights for obesity treatment.
Severe obesity can alter metabolism and psyche, leading to impulsive behavior and a willingness to take risks. A study found that massive weight loss improved glucose metabolism and mood, allowing for more metabolically driven decision-making.
A new study found that low energy availability among female athletes impairs performance by up to 18% in short-term tests and increases systemic stress, compromising immune function. Athletes who restrict their food intake experience muscle loss and decreased physical performance.
A review article by Uppsala University researchers highlights the global issue of malnutrition in the sick and elderly, affecting up to 50% of hospital patients in Sweden. Simple measures such as counselling, dietitian collaboration, and nutritional drinks can reverse malnutrition and improve quality of life.
A new study found that surgical weight loss significantly reduces widespread pain in Black and Hispanic patients, with the greatest benefit seen within the first three months after surgery. However, disparities persist, with these groups still experiencing a higher pain burden than the general population.
Researchers found that mice lacking certain signal molecules produced during exercise had reduced oxygen consumption and fat burning, leading to increased susceptibility to weight gain. In humans, those producing more of these alternative versions consumed less oxygen and had lower body fat.
Tirzepatide was associated with significantly greater weight loss than semaglutide in adults with overweight or obesity. Future studies are needed to explore differences in other outcomes.
A new study found that patients prescribed semaglutide for diabetes or weight loss have a higher risk of developing NAION, a potentially blinding eye condition. The study revealed a significant risk increase in diabetic and overweight/obesity patients taking semaglutide.
A new mouse study suggests that elenolic acid can lower blood sugar levels and promote weight loss in obese mice with diabetes. The compound was found to induce the release of metabolic hormones GLP-1 and PYY, leading to improved glucose regulation and insulin sensitivity.
Researchers found that people who achieved weight loss and prediabetes remission had a 76% lower risk of developing type 2 diabetes compared to those who only lost weight. This suggests that normalization of blood sugar levels should be included as a therapeutic goal in guidelines to improve diabetes prevention.
A randomized clinical trial found that combining exercise with glucagon-like peptide-1 receptor agonist (GLP-1RA) treatment was the most effective weight loss strategy while preserving bone health. In contrast, GLP-1RA treatment alone reduced bone mineral density at clinically relevant sites.
Research reveals close relationship between midlife diet and healthy aging; Limiting ultra-processed foods may not improve diet quality. Baby-led weaning meets nutritional needs for healthy growth, while whole grains retain more nutrients during milling.
Research debunks four common myths about intermittent fasting: it does not lead to a poor diet, cause eating disorders, excessive lean muscle mass loss, or affect sex hormones. Studies show both types of intermittent fasting (alternate-day and time-restricted) are safe despite popular misconceptions.
Women with obesity-related heart failure experienced greater weight loss and improved HF symptoms compared to men. Semaglutide improved HF-related symptoms, physical limitations, exercise function, reduced inflammation, and lower blood pressure across both sexes.
A randomized clinical trial found that an intermittent fasting plan consisting of two nonconsecutive fasting days and five days of meal replacement diet improved glycemic outcomes and weight loss in the short term compared to metformin or empagliflozin. The study suggests a promising initial intervention for type 2 diabetes management.
A list of evidence-based nutritional recommendations has been developed to assist clinicians in treating patients with anti-obesity medications. The recommendations aim to improve nutritional needs within the context of reduced food intake, and include ongoing monitoring of dietary intake and nutritional status.
In individuals with a diabetes duration of 10 years or less, bariatric metabolic surgery was associated with greater weight loss and reduced mortality compared to first-generation GLP-1RAs. No differences were observed between treatment modalities in patients with longer diabetes duration.
Research published in the Stroke journal found that teenage women who were overweight or obese had a higher risk of ischemic stroke before age 55. The study analyzed data from over 50 years and suggested that even temporary excess weight may have long-term health effects.
Research shows that GLP-1 receptor agonist drugs are highly effective for weight management and Type 2 diabetes treatment, but they come with complex considerations such as dosages, side effects, and comparisons between specific drugs. Experts caution against overusing these drugs or viewing them as a universal cure-all for obesity.
Current medical training neglects to educate future doctors on how to encourage healthier eating habits and focuses on weight loss and BMI. Researchers advocate for small changes in medical education to address anti-obesity bias and promote cardiometabolic health, a stronger predictor of overall well-being.
A study suggests that women who underwent sleeve gastrectomy before pregnancy had children who gained more weight per month in the first three years of life. In contrast, those born to mothers who had Roux-en-Y gastric bypass surgery experienced slower weight gain. Researchers found this difference after adjusting for various factors, ...
A recent study funded by tirzepatide maker Eli Lilly Inc. found that the medication resulted in significant weight loss regardless of the number of obesity-related complications patients had at the outset. The study combined data from four trials involving over 4,700 subjects with obesity or overweight conditions.
A new study found that tirzepatide significantly reduced weight in Chinese adults with obesity, with both 10mg and 15mg doses showing clinical benefits. The treatment also demonstrated an acceptable safety profile.
Wake Forest University School of Medicine has received a $1.5 million grant to study bone microarchitecture in patients following bariatric surgery. The researchers will use high-resolution peripheral quantitative computed tomography (HR-pQCT) imaging to assess bone loss and muscle changes after weight-loss surgery.
A new study highlights the benefits of intermittent fasting and protein-pacing on gut health, weight loss, and metabolic responses. Participants showed improved diversity of the gut microbiota, decreased symptoms of gastrointestinal problems, and increased beneficial microbes linked to a lean body type.
Researchers at Pohang University of Science & Technology developed a hybrid porous structure using polyvinyl alcohol, enabling uniform lithium electrodeposition. The new design facilitated the transport of lithium ions, reducing 'dead Li' areas and internal short circuits, resulting in high stability after 200 charge-discharge cycles.
A national study found a significant increase in the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) among adolescents and young adults in the US. Female adolescents showed a higher increase in GLP-1RA usage compared to males, highlighting the need for education on potential safety risks during pregnancy.
Research presented at Digestive Disease Week 2024 reveals the risks associated with weight-loss drugs and alpha-gal syndrome. Studies found that GLP-1 weight loss drugs may increase the risk of biliary disease and gastroparesis, while an alpha-gal syndrome diagnosis is linked to GI symptoms in females.
A new American Heart Association scientific statement reveals significant gaps in the application of obesity research to patient care, with widespread adoption varying by healthcare professional and institution. The statement emphasizes the need for better implementation of evidence-based treatments and strategies, such as lifestyle mo...
A new study led by UT Health San Antonio found that long-term ketogenic diets can induce senescence, or aged cells, in normal tissues, affecting heart and kidney function. However, an intermittent ketogenic diet regimen eliminated these pro-inflammatory effects.