Articles tagged with Weight Loss
This novel treatment approach yields better weight loss maintenance and cardiovascular risk outcomes compared to standard-of-care treatment. Patient-delivered lifestyle intervention combined with peer support significantly improves weight loss and reduces cardiovascular risk.
Bariatric surgery, a critical tool for combating obesity, is under threat in Australia due to skyrocketing indemnity insurance premiums. The study found that surgeons are being penalized by rising premiums, forcing some to reconsider their future in the field.
A new study from the University of Bath found that regular, moderate-intensity exercise preserves vitamin D levels in overweight and obese individuals. The study showed that exercise completely maintained the body's active form of vitamin D, which plays a key role in supporting bone health and the immune system.
A new study by York University suggests that the broad ethnic categories used in clinical settings may mask differences in sub-ethnic groups. The findings indicate that socio-economic factors play a significant role in weight loss disparities among Black, Middle Eastern, Latin, and South Asian communities.
A new analysis of 100 top TikTok videos about food noise found that half reference the use of medications, mainly anti-obesity drugs, to manage constant thoughts about food and eating. The study highlights the potential risks of misinformation on social media platforms like TikTok.
A study published in Molecular Motabolism found that prolonged water-fasting can increase inflammation and stress on the body, potentially exacerbating existing heart and vascular conditions. However, some benefits were observed, including a reduction in amyloid beta proteins associated with Alzheimer's disease.
SYNT-101 successfully redirects nutrient absorption to the lower intestine, promoting satiety and metabolic balance. The study demonstrated strong safety and tolerability profiles, as well as control of hunger and weight loss.
Researchers found that tirzepatide increases energy expenditure directly after treatment, while semaglutide reduces it. Both drugs aid weight loss by decreasing food intake and enhancing fat oxidation.
A new analysis of the SELECT trial shows semaglutide reduces major cardiovascular events by 40% within 3-6 months, even before significant weight loss and full target dose. The study found that semaglutide's effects on reducing inflammation, blood sugar, and blood pressure may contribute to its early clinical benefits.
Patients in an online obesity clinic achieved average weight loss of 16.7% after 64 weeks, similar to clinical trials of semaglutide, but using less than half the medication. The study found that personalized doses of semaglutide combined with behavioral therapy and support led to successful weight loss.
Researchers found that individuals who consumed collagen-enriched protein bars lost twice as much weight as a control group. The supplement also improved blood pressure, waist circumference, and liver health. Participants reported feeling less hungry and more full.
A new head-to-head study has shown that tirzepatide results in around 50% more weight loss than semaglutide in adults with obesity. The study found that tirzepatide led to an average weight loss of 20.2%, significantly higher than the 13.7% achieved with semaglutide.
Researchers found that GLP-1 receptor agonists have a direct effect on reducing obesity-related cancer beyond weight-loss, with a 41% lower relative risk compared to bariatric surgery. The study also suggests that these medications work through multiple mechanisms, including reducing inflammation.
A systematic review of available evidence found GLP-1 RAs lead to significant weight loss and improved blood sugar control in adults with severe mental illness. The analysis also showed that these medications were not associated with a worsening of mental state or suicidal behaviour.
Researchers found that a 3-month program of time-restricted eating at any time of the day can result in significant weight loss for at least a year, regardless of eating window timing. The study suggests that restricting the eating window to 8 hours may be an effective long-term approach for sustaining weight loss.
Researchers found that silencing Mitch, a key regulator of mitochondrial fusion, increases cellular respiration and burns more fats and carbohydrates. In human cells, deleting Mitch leads to increased muscular endurance and a decrease in fat accumulation.
Researchers at Pennington Biomedical Research Center investigated tirzepatide's effects on weight loss and metabolic health. The study found that tirzepatide decreased calorie intake and increased fat oxidation, leading to significant weight loss. However, the drug did not decrease the slowing down of metabolic rate usually observed wi...
A study published by the European Association for the Study of Obesity found that women are significantly more aware of and have a better understanding of obesity drugs like semaglutide and tirzepatide. Understanding tolerable side effects, effectiveness, and ability to maintain weight loss is crucial for people commencing treatment.
A study of nearly 2 million people found that the use of GLP-1RA-based medications increased from 13% to 35% among those with type 2 diabetes, while traditional medications like metformin declined. Tirzepatide saw a steeper and more sustained rise in its use compared to other recently approved medications.
A new study found that tirzepatide can produce sustained weight loss of up to 31% in adults with overweight or obesity without diabetes, regardless of age or BMI. The study also identified patterns of weight loss trajectories and found that females and those without obesity-related complications may be more responsive to the medication.
A new analysis of the SURMOUNT-1 trial found that around two-thirds of participants regained only 5% or less of their lowest weight over three years. The study suggests that most patients receiving tirzepatide had a relatively stable weight journey, with limited weight regain after reaching their nadir weight.
A six-month study found that patients using GLP-1 and dual GLP-1/GIP receptor agonist therapy experienced minimal lean muscle mass loss as they lost weight. Regular resistance training, consistent protein intake, and close supervision by an expert obesity doctor were associated with better muscle retention.
Research found that people taking GLP-1s consume less processed foods, soda, refined grains, and beef, but still desire them. The study also showed an increase in consumption of fruits, leafy greens, and whole grains among GLP-1 users.
The Endocrine Society strongly disagrees with the administration's decision not to finalize a rule allowing Medicare and Medicaid to cover anti-obesity medications. This decision leaves millions of Americans with obesity without access to evidence-based treatment, exacerbating the country's growing obesity epidemic.
The American College of Physicians has awarded $260,000 in grants to support regional programs addressing equity challenges in obesity care. Thirteen grantees will implement collaborative outreach projects to train medical professionals and their patients to combat misinformation and improve clinical capacity for obesity care.
A new review of studies on percentage weight-based targets in obesity interventions found that these targets often result in a 'success or failure' outcome, leaving little room for improvement in obesity-related complications, quality of life, and overall physical and social functioning. The study recommends shifting focus towards more...
A new paper highlights emerging alternatives to traditional diabetes medicines, such as continuous glucose monitors and lifestyle interventions like GEM, which can improve patient adherence and long-term health outcomes.
A randomized clinical trial found that 4:3 intermittent fasting resulted in modestly greater weight loss over 12 months compared to daily caloric restriction. The study showed improved cardiometabolic outcomes, including lower blood pressure and cholesterol levels, suggesting that fasting may be a more effective approach for weight loss.
A four-year study presented at the American College of Cardiology's Annual Scientific Session found that oral semaglutide reduced cardiovascular death, heart attack, and stroke by 14% compared to a placebo. The drug's benefits are comparable to injectable forms and offer an alternative for patients who prefer not to take injections.
A new white paper finds that expanding access to anti-obesity medications can prevent or delay chronic disease by years, providing significant societal benefits. The study estimates a $10 trillion return on investment and 13% annual returns on investment for society.
A high-fat diet reduces neurotensin, a brain peptide that interacts with the dopamine network, leading to reduced pleasure in eating. Boosting neurotensin levels restores pleasure and promotes weight loss in mice, offering new avenues for addressing obesity.
A new study from the University of Mississippi finds that time-restricted eating combined with regular exercise leads to more significant fat loss and reduced body fat percentage compared to exercise alone. However, lean mass preservation was maintained in this study, contradicting previous concerns about potential muscle loss.
New research suggests that maintaining a healthy weight throughout life and losing weight later in life may reduce the risk of kidney cancer. Higher BMI at various ages across adulthood was associated with increased risks of developing different types of kidney cancer, including renal cell carcinoma, papillary RCC, and chromophobe RCC.
A new technology called in vivo antibody painting enables sustained weight loss and prolonged blood sugar management with a lower dose of GLP-1 receptor agonist. The system, developed by MIT professor Bradley Pentelute, attaches peptides directly to antibodies, overcoming the limitation of peptide degradation.
A Swedish study of over 1,300 participants found that losing a significant amount of weight still offers protection against health issues like cancer and cardiovascular disease, even if some weight is regained. However, regaining weight can increase the risk of microvascular disease and other health problems.
A new study from the University of Surrey found that healthcare professionals face difficulties in recognizing and addressing disordered eating in people with type 1 Diabetes due to lack of support and limited confidence. This can lead to delays in diagnosis and potentially life-threatening complications for patients.
Replacing animal products with plant-based foods, even highly processed ones, can lead to substantial weight loss due to reduced calorie and fat intake and increased fiber consumption. This is according to a new analysis of a randomized clinical trial published in Nutrition & Metabolism.
A recent study published in Heart journal found that extreme weight fluctuations significantly increase the risk of death among obese individuals with cardiovascular disease. Both weight loss and gain above 10kg raise mortality risk, highlighting the importance of maintaining a stable weight even within the obese range.
A pooled data analysis found that water aerobics can effectively reduce overall weight and trim waist circumference by 3 cm in obese or overweight participants. Exercise periods lasting more than 10 weeks significantly reduced body weight and waist circumference in women and those aged 45 and older.
A new study found that the proportion of visceral fat, rather than the absolute amount, is a stronger predictor of high triglyceride levels and inflammation. Lowering visceral fat proportion during weight loss can lead to better metabolic health outcomes.
A study of 350 patients found that taking semaglutide before bariatric surgery did not increase total weight loss and had similar health outcomes to surgery alone. Researchers suggest a surgery-first strategy may lead to better obesity treatment outcomes.
Complimentary press passes are available for NUTRITION 2025, exploring cutting-edge research on nutrition and public health. Media professionals can attend in person or access virtual newsroom materials before the meeting.
Researchers developed a novel approach using electrospun poly(Lactic-co-Glycolic Acid) membrane with autologous cells to treat oral mucositis, a painful side effect of chemotherapy. The study showed significant results, with ulcers healed completely within six days and reduced inflammation.
A two-month intervention targeting ultra-processed foods resulted in a significant reduction of UPF intake, with participants consuming almost half the amount initially. Participants also experienced weight loss, improved mood, and reduced sugar, saturated fat, and sodium consumption.
A cohort study found that patients with obesity undergoing joint replacement who experienced significant weight loss after initiating anti-obesity medications had a lower risk of 5-year and 10-year revision. This suggests that safe and sustainable weight loss may improve implant survivorship in obese patients.
A systematic review of 38 studies found that frequent use of health and fitness apps is associated with problematic habits related to food and exercise. The research highlights the need for app developers to consider the psychological impacts of these tools on users' mental health.
Researchers found that teens with obesity consumed more calories in the late afternoon and early evening compared to their peers of healthy weight. The study, published in PNAS, demonstrates that the body's biological clock directly impacts food intake throughout the day.
Researchers found that bimagrumab increases bone tissue while building muscle mass, reducing the risk of osteoporosis. The study suggests bimagrumab could be part of a second-generation weight loss drug on the market.
A new study found that yo-yo dieting significantly increases the risk of kidney disease in people with type 1 diabetes. Participants who experienced greater weight fluctuations had a 40% decline in estimated glomerular filtration rate and were more likely to exhibit increased albuminuria.
A recent study published in Plastic and Reconstructive Surgery found that breast reduction surgery can lead to weight gain in adolescents and young women, particularly those who were at a healthy body mass index (BMI) before surgery. The study suggests that these patients should be targeted for healthy lifestyle changes to prevent weig...
A recent study by Murdoch University reveals that moderate-intensity exercise significantly influences appetite-related hormones and perceptions in males with obesity. The study confirms the benefits of incorporating regular exercise into daily routines for weight management and overall health improvement.
The University of Illinois team developed MealPlot, an interactive feature that charts protein and fiber content in food. The app helps individuals plan meals with a focus on high protein and fiber density to achieve a calorie deficit while maintaining muscle mass.
A new study from the Salk Institute has discovered that a protein called BCL6 plays a crucial role in maintaining healthy muscle mass. Increasing BCL6 levels successfully reversed muscle losses in mice, suggesting that pairing GLP-1 medications with a BCL6-boosting drug could help counteract unwanted muscle loss.
A large population-based analysis found that genetic variants in the GLP1R gene are associated with cardiometabolic traits and behavioral changes, such as risk-taking behavior and anxiety. These findings suggest that any observed behavioral changes with GLP1RA medications are unlikely to be a direct result of the medication.
A new study found disparities in access to semaglutide based on insurance plan, job industry, sex, and other factors. Individuals with female identities, preferred provider organization coverage, and antidepressant use were more likely to start taking semaglutide compared to males or those with certain employment industries.
A recent study published in Nature Medicine analyzed over 2 million veterans taking GLP-1RA medications, finding benefits to cognitive and behavioral health while revealing increased risks for pancreatitis and kidney conditions. The study also showed decreased risks of seizures, addiction, suicidal ideation, and neurocognitive disorders.
A new Cochrane review found that calorie labelling in supermarkets, restaurants, and other food outlets leads to a small reduction in the calories people select and purchase. The average reduction was 1.8%, equating to around two almonds per 600-calorie meal.
A new study by Mass General Brigham investigators found that Black people were less likely than non-Black people to undergo metabolic and bariatric surgery, even though both groups were equally likely to discuss it with health care providers. Men were also less likely to discuss and receive MBS than women.
A new national survey by Orlando Health finds that 56% of Americans are unaware that bariatric surgery is an effective way to improve fertility. Bariatric surgery has been shown to regulate hormones and normalize menstrual cycles, increasing a woman's chances of conception. The study highlights the connection between obesity and infert...
Researchers analyzed cost-effectiveness of semaglutide for non-diabetic overweight/obese individuals with heart disease. With price reductions, semaglutide shows promise in reducing lifetime costs and improving health outcomes.