Articles tagged with Parasites
Researchers have developed a database of parasite-host interactions among ancient ocean animals, shedding light on the evolution of biodiversity and the impact of parasitism on ecosystems. The study suggests that parasites can positively stabilize coastal ecosystems, making them more stable despite individual harm to hosts.
Researchers at the Paul Scherrer Institute have identified a chemical compound, parabulin, that can inhibit the protein tubulin in unicellular parasites, including those that cause malaria and toxoplasmosis. The substance blocks successful cell division by preventing tubulin from forming long, stable protein filaments.
Scientists have developed a technique to sequence individual malaria parasites' genomes, allowing for the detection of new mutations. These mutations are often targeting a gene family controlling transcription in malaria, suggesting potential avenues for developing more effective treatments and vaccines.
A Brazilian study found that children exposed to malaria from birth are more likely to develop anemia by age two. The researchers, led by Dr. Marly Augusto Cardoso, followed 1,539 children and discovered that 12.6% were anemic, with a higher prevalence in rural areas not covered by the study.
Chronic P. vivax infections cause significant damage to kidneys, brain, and circulatory system, affecting impoverished communities. The parasite can hide at low levels, making diagnosis difficult and treatment efforts challenging.
Researchers found that brood parasites have larger eyes than host birds, which may help them avoid detection. Birds with larger eyes relative to their body mass are also less likely to have their nests parasitized.
A Duke University-led study finds that if endangered primates disappear, up to 250 parasites could go extinct, including those with no other suitable hosts. This potential extinction cascade could have significant consequences for biodiversity and human health.
Researchers find hookworms resistant to multiple drugs used to treat them, with high prevalence in racing greyhounds. The study's results highlight the importance of regular deworming and caution against dog parks as potential breeding grounds for drug-resistant parasites.
A new study led by Rachel Penczykowski investigates the hydra effect in water fleas, where parasite infections trigger a counterintuitive increase in population density. The researchers found that infected water fleas consume less algae, leading to an abundance of resources for uninfected individuals.
A team of researchers has discovered a new group of coral-infecting microbes called Corallicolida. Despite lacking photosynthetic genes, they express chlorophyll genes and may still play a role in their host cells. The authors propose that Corallicolida could be an ancient parasite that lost its photosynthetic machinery.
Eosinophils, a type of white blood cell, play a crucial role in destroying malignant tumors by recruiting T-cells and releasing destructive proteins. The study, published in Cancer Research, reveals that eosinophils combat cancer effectively but require the help of T-cells to do so.
Researchers found a new species of candiru attached to the surface of an Amazonian thorny catfish, suggesting a commensalistic relationship where the parasite benefits without harming its host. The discovery challenges traditional views of vampire fish and highlights the complexity of these unusual relationships.
A new study led by ISGlobal has identified a gene called PfAP2-HS that allows the malaria parasite to defend itself from febrile temperatures and other adverse conditions within the host. The study found that this gene activates a protective response against high temperatures, helping the parasite survive in the host's environment.
Researchers found medium tree finch nests with high parasite survival rates, while hybrid finches had lower rates. Nestling behaviour also predicted naris deformation due to vampire fly parasitism.
Researchers used mass cytometry and machine learning to discover 'immune signatures' that differentiate between symptomatic and asymptomatic Plasmodium vivax malaria infections. The study found a previously unrecognised role for immune CD4 T cells in preventing serious disease and controlling asymptomatic infection.
Researchers define the atomic-level architecture of a protein-receptor connection that allows the malaria parasite to evade the immune response. A drug designed to fit into this space could block the interaction, allowing the immune system to clear away the pathogen and potentially reducing severe malaria cases.
A new malaria vaccine has shown unprecedentedly high levels of durable protection in phase 1 trials, potentially reversing the stalled decline of global malaria. The vaccine combines live parasites with antimalarial drugs and has induced sterile hepatic immunity.
A Sanaria vaccine has demonstrated complete protection against a variant malaria parasite in six subjects, with the dosage being only 20% of its original strength. The results, published in Nature, have significant implications for the prevention of malaria in African populations and travelers to Africa.
Researchers found that parasitic hairworms in praying mantis infected with parasites are attracted to horizontally polarized light and enter the water. This manipulation of host behavior is a remarkable example of how parasites can alter their hosts' morphology and behavior for their own benefit.
Research from the University of Colorado Boulder reveals that Toxoplasma-infected hyena cubs are more bold and approach lions from closer distances, leading to a higher risk of death. The parasite has a direct and detrimental impact on hyena fitness.
Researchers at Oregon State University have identified a new genus and species of fungal parasite in an ancient ant fossil, shedding light on the origins of this complex relationship. The discovery, published in Fungal Biology, reveals that the fungus can manipulate its host ant's behavior to facilitate its own reproduction.
A rare parasitic infection is spreading rapidly in Alberta, with over 17 human cases diagnosed between 2013 and 2020. The disease, known as alveolar echinococcosis, causes serious health complications and can be deadly if left untreated.
A new method for collecting pure malaria parasites from infected mosquitoes could accelerate the development of new, more potent malaria vaccines. The 'mosquito smoothie' innovation enables rapid purification with fewer contaminants, increasing scalability and efficacy.
A study in Uganda reveals that school-aged children with asymptomatic malaria are a significant source of mosquito infections, driving the spread of the disease. Targeting these children for control interventions could help sustain malaria gains and prevent resurgences.
Using lattice light sheet microscopy, researchers captured high-resolution videos of individual malaria parasites invading red blood cells, revealing key steps in the parasite life cycle. The study's findings may lead to new antimalarial therapies by targeting specific components of the parasite, potentially bypassing drug resistance.
Researchers at Martin-Luther-University Halle-Wittenberg have developed a simple method to prepare artemisone, a promising substance against malaria. The new formulation shows improved efficacy in combating harmful parasites, reducing the need for high doses and potential side effects.
Recent studies have demonstrated excellent efficacy of Sanaria's PfSPZ-CVac malaria vaccine, with 77% protection rate in malaria-naive adults. Optimizing immunization timing has increased efficacy to 75%, overcoming negative impacts of blood stage parasites.
A study published in PLOS Medicine reveals that malaria parasites survive and replicate within the spleen of asymptomatic individuals infected with Plasmodium vivax. The research found a substantial biomass of intact asexual-stage malaria parasites accumulated in the spleen, targeting immature red blood cells for invasion.
A study found that malaria parasite Plasmodium vivax accumulates in the spleen to a greater extent than its relative P. falciparum after infection. Imaging techniques revealed increased glucose metabolism in the spleen of participants infected with P. vivax.
A comprehensive genetic resource of rat-infecting malaria parasites has been published, providing insights into the evolution, virulence, and transmissibility of the disease. The study reveals diverse genetic and phenotypic variations between subspecies, which may aid in understanding malaria parasite gene functions.
Researchers have mapped the genetic changes of malaria parasites in unprecedented detail, revealing new targets to block key stages in the parasite's development. This could lead to new ways to prevent transmission through future drugs or vaccines.
Researchers sequenced the genomes of three socially parasitic ant species, finding evidence of widespread genomic rearrangements and gene losses. The study sheds light on the evolutionary consequences of transitioning from social to parasitic behavior, with significant impacts on sensory capabilities and behavioral repertoire.
Researchers have designed a new drug compound that effectively blocks a critical step in the malaria parasite life cycle, trapping it in the cell and preventing its replication. The compound works by blocking an enzyme called SUB1, which is crucial for the parasite's exit route from red blood cells.
A live vaccine consisting of infectious Plasmodium falciparum parasites has been shown to be highly effective in preventing malaria, with only three immunizations required. The vaccine induces a strong immune response that can recognize both the injected parasites and subsequent liver stage antigens.
Researchers at George Mason University are studying the impact of castrating parasites on an estuarine crab host in the Chesapeake Bay. They will investigate how environmental salinity affects parasite survival and metamorphosis.
Researchers have identified how natural human antibodies can block malaria parasites from entering red blood cells, potentially indicating the development of new protective therapies. This discovery opens up new avenues for developing antibody-based therapies for malaria.
A study by Brandi Wren found that monkeys carrying whipworm parasites exhibit reduced social grooming and cuddling, implying a link between infections and behavioral changes. This research opens new avenues for understanding animal behavior and human health, particularly in the context of social distancing and contagion.
Researchers found that certain gut microbes, specifically Asaia bogorensis, increase the risk of malaria parasite infection in mosquitoes by raising gut pH levels. Feeding mosquitoes a sugar diet promotes the proliferation of this bacterial species, which enhances parasite infection.
A new dataset includes over 21,000 interactions between 942 species, thoroughly annotated, providing a detailed look at kelp forests. The study highlights unseen parasite interactions that have been overlooked by ecologists.
New data reveals that mutations in the malaria parasite Plasmodium falciparum may be gaining a foothold in Africa, linked to delayed parasite clearance. The study finds that these mutations are more prevalent than previously reported, raising concerns about further geographical spread of resistance.
A team of scientists simulated the task of piercing an egg to understand how host birds defend against brood parasites. They found that nests and tool shape significantly affect the mechanics and energy requirements of avian eggshell puncture.
Researchers found that dogs infected with Leishmania parasites have a more attractive odor to female sand flies than uninfected dogs. This increased attractiveness could lead to enhanced infection and transmission opportunities for the parasite.
A study found that infected dogs emit an odor attractive to female sand flies, which transmit Leishmania infantum, the parasite causing visceral leishmaniasis. The researchers suggest parasites manipulate their host's scent to improve transmission opportunities.
A newly-discovered non-coding RNA molecule regulates protein translation in trypanosoma parasites, a key finding with potential applications in treating and preventing diseases such as sleeping sickness. The discovery sheds light on the previously unknown function of rRNA introns and may lead to the development of novel medications.
Researchers at UNIGE have discovered a vestigial form of conoid organelle in the malaria parasite, which could play a role in host invasion. The study uses expansion microscopy to view the parasite's cytoskeleton at an unprecedented scale, shedding new light on its life cycle.
Researchers analyzed blood samples from over 1,000 bird species to understand malaria ecology. They found that the strains of malaria present in a local area don't always align with the types of birds living there, instead being influenced by weather patterns such as rainfall.
A new study found that the transmission risk for schistosomiasis peaks when water warms to 21.7 degrees centigrade, increasing with climate change. Implementing snail control measures can reduce transmission but raises peak transmission risk to 23 degrees Fahrenheit.
Researchers have confirmed that parasites can parasitize newly-recorded snail species in Thailand, posing a risk of food-borne zoonotic diseases. The study highlights the need for further research on the biodiversity and biology of these snails to improve public health understanding.
Lauren Childs and her team have developed a mathematical model that shows providing multiple blood meals to female mosquitoes can increase the transmission of malaria. The study suggests reducing mosquito egg production could also accelerate parasite growth, shortening the incubation period.
A recent study published in Communications Biology analysed the relationship between parasite dispersal capacity and genetic introgression rates. The research found that species with higher dispersal abilities present increased genomic signatures of introgression, which could have implications for understanding parasite-host dynamics.
A £2.3 million project will study the Leishmania parasite, which causes leishmaniasis and affects some of the world's poorest communities. The research aims to understand how humans are infected and how the disease spreads, potentially leading to more effective treatments.
A new root-knot nematode species has been discovered on grapevines in Yunnan province, China. The Meloidogyne vitis sp. nov. species is believed to seriously damage grape production, highlighting the need for further research and monitoring.
A new malaria mosquito species, Anopheles stephensi, has been found in cities and towns in urban settings in Ethiopia, Sudan, and Djibouti. The invading mosquito is highly susceptible to local malaria strains, increasing the risk of urban malaria in Africa.
Researchers from the University of Copenhagen have made a groundbreaking discovery about malaria, showing that the parasite can cross the blood-brain barrier using a mechanism employed by immune cells. This breakthrough provides new insights into the disease process behind cerebral malaria and its severe neurological consequences.
A new study by ISGlobal has identified six microRNAs that may be used as biomarkers to predict disease severity in children with severe malaria. The findings provide a potential breakthrough in understanding the mechanisms underlying severe malaria and improving treatment outcomes.
Researchers have deciphered the structure of a protein found in parasites that cause elephantiasis and cutaneous leishmaniasis, enabling the search for more potent molecules capable of directly destroying pathogens. The study aims to reduce or avoid adverse side effects of current treatments.
Researchers discover new mutations in malaria parasite that enhance resistance to sulfadoxine-pyrimethamine, a key preventive drug. These mutations are already widespread in Africa and Asia, threatening efforts to use the drug to prevent malaria in vulnerable groups.
A study published in PLOS Pathogens reveals that mosquitoes feeding on blood multiple times increase malaria transmission potential, shortening the incubation period and making disease control more challenging. The research suggests that younger mosquitoes with reduced reproductive ability may contribute to infection, undermining curre...
Researchers at the University of Zurich have developed a genetic engineering method to prevent Toxoplasma gondii parasite production, which causes toxoplasmosis. The new technique uses CRISPR-Cas9 gene editing scissors to switch off essential genes responsible for oocyst formation without leaving unwanted traces.
Researchers have developed a cell atlas of Schistosoma mansoni, a parasitic worm that poses a risk to hundreds of millions of people each year. The study identified 13 distinct cell types within the worm at the start of its development, including new cell types in the nervous and muscular systems.