Articles tagged with Parasites
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study published in PLOS Biology reveals the significance of kinesins in basic cellular processes needed for malaria parasite development, multiplication and invasion. Researchers found that eight out of nine kinesins present in the parasite genome are required for cell proliferation to cell movement in mosquito hosts.
Researchers have developed an algorithm to identify the protozoan Trypanosoma cruzi in photographs of blood samples taken with a mobile phone camera. The low-cost method can be reproduced and adapted for other purposes that depend on images, such as analyzing feces, skin, or colposcopies.
Researchers used Plasmodium falciparum 7G8 challenge trials to test the PfNF54-based PfSPZ Vaccine, providing conservative predictions of its efficacy in Africa. The study found that VE over 24 weeks was as good as or better than VE against Pf7G8 CHMI at 24 weeks.
A unique fungus infects common houseflies, causing them to become necrophilic and mate with infected female corpses. The longer the corpse remains dead, the more attractive it becomes to male flies, allowing the fungus to spread its spores.
Researchers found that different lineages of Cryptosporidium parvum are increasingly exchanging their DNA, which helps the parasite evolve faster and potentially result in more virulent strains. The study suggests that globalization and close contact with animals increase the rate of genetic exchange.
A new digital PCR technique helps identify mutations in malaria parasites that evade detection by rapid tests, reducing false negatives. This allows for more accurate selection of diagnostic tests tailored to specific regions.
Researchers found no association between social behavior and parasite infection in Asian elephants, despite studying three key aspects of their social life. The study suggests that social benefits may outweigh the costs of sociality for these animals.
Researchers from Osaka University have developed a system to coat nematodes with hydrogel sheaths that can carry functional cargo. The study found that the sheaths protect the worms from UV light and hydrogen peroxide while allowing them to deliver anti-cancer agents to kill cancer cells in vitro.
Researchers analyzed DNA of Demodex folliculorum mites living in human hair follicles, finding unusual body features and behaviors due to their isolated existence. The study suggests these mites may transition from external parasites to internal symbionts as they shed unnecessary genes and cells.
Research on two worm phyla provides clues on how separate sexes originated and evolved in animals. The study characterizes the evolution of sex chromosomes in flatworms and roundworms, revealing that their diversity is a result of different combinations of genetic elements.
A UC Riverside genetic discovery found that mosquitoes lack the primary ecdysone transporter, allowing researchers to develop a mosquito-specific insecticide. This breakthrough could help control Zika, dengue, and other virus-carrying mosquitoes without harming beneficial insects.
Researchers found that increasing serotonin levels in mosquito blood reduces their flight speed and motivation to seek second blood meals, making them less efficient vectors of malaria parasites. This discovery provides a promising new avenue for insect-targeted interventions to prevent malaria transmission.
Researchers found that flower shape is a key predictor of parasite transmission to bees, with wider, shorter flowers increasing the risk. The study suggests that identifying floral traits and species associated with lower parasite transmission rates could help create pollinator habitats with reduced disease risk.
A UVA researcher is using a harmless amoeba to develop an innovative treatment for deadly C. difficile infections in young children. The approach has the potential to deliver specific antibodies directly to the gut, reducing the need for antibiotics and addressing a growing public health threat.
A study published in Journal of Pharmaceutical Analysis found that the quality of mistletoe, a traditional Chinese medicine, is affected by its host plant. The researchers used metabolomics to investigate the influence of host plants and environmental factors on mistletoe's medicinal qualities. The results show that both host plants an...
An international study uncovered a network of gastrointestinal parasite sharing among 17 wild and domestic herbivore species. The researchers found that host evolutionary history and gut type are key factors in determining parasite diversity and similarity.
Researchers have identified an anti-malarial compound, ML901, that inhibits the malaria parasite without harming mammalian cells. The compound works by hijacking a reaction to make the parasite self-destruct, showing rapid and prolonged action against resistant strains.
A WHO-supported series has collected 13,700 new database records on mosquito-borne diseases, providing valuable resource for studying and containing infectious diseases. The data can be used to train machine-learning models for vector detection and classification, improving global human health.
The São Paulo School of Advanced Science on Pathogenic Trypanosomatids will bring together experts from different fields to discuss the fight against leishmaniasis and Chagas disease. Researchers will share state-of-the-art science and results of new research on epigenetics, drug discovery, and molecular biology.
Researchers have captured the first 3D images of malaria parasites and how anti-malarial compounds like PMIX and PMX work to stop their spread. The findings will enable the design of new compounds that can effectively block Plasmepsins, preventing malaria parasite replication.
Researchers from Clemson University have discovered a promising therapy for toxoplasmosis, a disease caused by the microscopic protozoa Toxoplasma gondii. The team has enlisted an unlikely ally - the herbicide oxadiazon - in the fight against the single-celled parasite.
A novel genetic screening technique identified two genes crucial for Toxoplasma gondii cell egress, leading to the death of parasites within host cells. This breakthrough paves the way for the development of new drugs that could block parasite propagation.
Researchers at Karolinska Institutet have mapped the formation of hybrid strains in Trypanosoma cruzi, a parasite causing chronic infection and severe symptoms. These hybrids are more effective at evading the immune system and causing disease, but understanding their formation can help develop new diagnostic and treatment methods.
A study led by Washington University in St. Louis found that nonlethal parasitic infections reduce herbivory rates and trigger trophic cascades impacting plant communities. The research used a mathematical model and global meta-analysis to highlight the ecological consequences of common parasitic infections in wild animals.
A recent study has revealed that the RTS,S malaria vaccine not only elicits antibodies against specific antigens but also those of other parasites, leading to increased protection. This off-target antibody response is significantly associated with reduced risk of clinical malaria in vaccinated children.
Research reveals high rates of parasitic worm infections in ancient British populations, particularly during the Roman and Medieval periods. The study sheds light on the lives and habits of past populations, providing insights into public health measures.
Researchers have discovered that P. malariae, a malaria parasite infecting humans, originated in African apes before evolving to infect people. This breakthrough reveals the evolutionary links between the two species and sheds light on how the parasite adapted to infect humans.
Researchers found that social bee parasites and their host species have similar rates of evolution, contrary to predictions. This unexpected finding suggests that smaller population sizes may not hinder a parasite's ability to adapt and survive.
Researchers discovered that freshwater pearl mussel larvae can protect brown trout from Flavobacterium disease outbreaks. The mussels' filtering ability removes bacteria from water, suggesting a potential application in water treatment. This finding highlights the importance of ecosystem services provided by endangered species.
Researchers discover that common herbicides can kill the Toxoplasma gondii parasite without harming human cells. The compounds work by inhibiting heme biosynthesis, a promising approach for treating toxoplasmosis.
A new mechanism has been discovered that decorates the end tails of RNA molecules in a parasite causing sleeping sickness, preventing their degradation and potentially increasing virulence. This fundamental discovery opens new avenues for treatment strategies for this disease, as well as other RNA-based infections/diseases.
A new analysis from Emory University reveals a significant increase in the parasitism rate of monarch butterflies over 50 years, with the O.E. parasite infecting up to 10% of eastern monarch populations. The rise in infection rates may endanger the mass migration of monarchs, threatening their survival.
Researchers have developed a vaccine using CRISPR technology to protect against Leishmania mexicana, a parasite causing cutaneous leishmaniasis in the Americas. The vaccine is safe and effective in mice, preventing skin lesions and infection for over 10 weeks.
A team of scientists led by Karine Le Roch has identified two proteins, RAP01 and RAP21, crucial to the malaria parasite's survival. Knocking down these proteins can interrupt protein translation in the mitochondria, leading to the parasite's death.
Researchers found that the ability to detect a parasite and launch an immune response quickly is key to resisting parasites, with implications for understanding human conditions with scar tissue. The study's findings could lead to new treatments and faster recovery times for humans with diseases like cystic fibrosis and liver fibrosis.
A new study by Emory University finds that schistosome transmission can be highest when freshwater snail populations are low. Snails competing for resources may lead to lower infectivity rates, contrary to typical pesticide-based control methods.
Researchers at Weill Cornell Medicine have identified a protein called HDP1 that plays a critical role in activating genes required for the development of male and female stages of the malaria parasite. Without HDP1, parasites are unable to assemble mature gametocytes, leading to their death and inability to infect mosquitoes.
Researchers discovered a new parasite, Txikispora philomaios, which evolved shortly after the common ancestor of animals and fungi, before its multicellularity was developed. The study provides insights into how animal multicellularity developed through cell communication and specialization.
Scientists at UCR have discovered a new species of nematode parasite that infects and kills tarantulas, exhibiting strange behaviors like walking on tiptoe and loss of fang control. The parasite, Tarantobelus jeffdanielsi, is named after actor Jeff Daniels, who saved fictional spiders in the 1990 film Arachnophobia.
Researchers discovered that pathogens can hijack mitochondrial defense mechanisms by mimicking host proteins, effectively disarming the mitochondria. This allows the pathogen to acquire essential nutrients and evade the host's immune response.
Researchers discovered nine genes in S. mansoni's autophagy pathway inhibited by the primate's immune system, preventing parasite multiplication and contaminating the host. The study suggests a potential novel therapy and vaccine against schistosomiasis.
Two independent teams of researchers have found the molecular mechanism of action of praziquantel, the only approved drug to treat schistosomiasis. The drug binds to a specific type of channel in the cell membrane, causing calcium ions influx and resulting in worm paralysis and death.
Researchers at UNICAMP discovered that total parasite biomass is a better predictor of complications in patients with P. vivax malaria than parasitemia. The study highlights the importance of parasite biomass in the bone marrow and spleen, which play a major role in vivax malaria complications.
Researchers from Ethiopia and Germany identified a traditional African medicinal plant that alleviates malaria symptoms in infected mice. The plant extract's active compound, anemonin, shows promise in treating the disease.
Researchers found that in 2020, 93% of Guinea worms detected worldwide were in dogs in Chad. Dogs eating infected fish carry the parasite larvae, which means they maintain the life-cycle and humans can still catch the disease.
A collaborative research study found Cryptosporidium prevalence to be 20-25% across Belgium, France, and the Netherlands, posing a serious threat to dairy cattle and human life. The parasite is concerning due to its ability to become infectious in chlorine, increasing the risk of infection through traditional methods.
A new study by Royal Holloway University of London found that glyphosate has no significant effect on bumble bee mortality, reproduction, or sucrose consumption. The research also suggests that the pesticide does not make parasite infections more intense at environmentally realistic concentrations.
A new diagnostic guide for pythium damping-off and root and stem rot of cucurbits has been published, providing a concise resource for growers, diagnosticians, and plant pathologists. The guide summarizes techniques for isolating, identifying, and testing Pythium isolates to combat these diseases.
A new study found that free-roaming domestic cats are the likely cause of toxoplasmosis in wildlife, with healthy ecosystems providing protection against these pathogens. The researchers suggest limiting cat roaming can reduce the impact of Toxoplasma on wildlife.
Researchers have developed a database of parasite-host interactions among ancient ocean animals, shedding light on the evolution of biodiversity and the impact of parasitism on ecosystems. The study suggests that parasites can positively stabilize coastal ecosystems, making them more stable despite individual harm to hosts.
Researchers at the Paul Scherrer Institute have identified a chemical compound, parabulin, that can inhibit the protein tubulin in unicellular parasites, including those that cause malaria and toxoplasmosis. The substance blocks successful cell division by preventing tubulin from forming long, stable protein filaments.
Scientists have developed a technique to sequence individual malaria parasites' genomes, allowing for the detection of new mutations. These mutations are often targeting a gene family controlling transcription in malaria, suggesting potential avenues for developing more effective treatments and vaccines.
A Brazilian study found that children exposed to malaria from birth are more likely to develop anemia by age two. The researchers, led by Dr. Marly Augusto Cardoso, followed 1,539 children and discovered that 12.6% were anemic, with a higher prevalence in rural areas not covered by the study.
Chronic P. vivax infections cause significant damage to kidneys, brain, and circulatory system, affecting impoverished communities. The parasite can hide at low levels, making diagnosis difficult and treatment efforts challenging.
Researchers found that brood parasites have larger eyes than host birds, which may help them avoid detection. Birds with larger eyes relative to their body mass are also less likely to have their nests parasitized.
A Duke University-led study finds that if endangered primates disappear, up to 250 parasites could go extinct, including those with no other suitable hosts. This potential extinction cascade could have significant consequences for biodiversity and human health.
Researchers find hookworms resistant to multiple drugs used to treat them, with high prevalence in racing greyhounds. The study's results highlight the importance of regular deworming and caution against dog parks as potential breeding grounds for drug-resistant parasites.
A new study led by Rachel Penczykowski investigates the hydra effect in water fleas, where parasite infections trigger a counterintuitive increase in population density. The researchers found that infected water fleas consume less algae, leading to an abundance of resources for uninfected individuals.
A team of researchers has discovered a new group of coral-infecting microbes called Corallicolida. Despite lacking photosynthetic genes, they express chlorophyll genes and may still play a role in their host cells. The authors propose that Corallicolida could be an ancient parasite that lost its photosynthetic machinery.
Eosinophils, a type of white blood cell, play a crucial role in destroying malignant tumors by recruiting T-cells and releasing destructive proteins. The study, published in Cancer Research, reveals that eosinophils combat cancer effectively but require the help of T-cells to do so.