Researchers at Massachusetts General Hospital found that using nanomedicines at lower, more frequent doses can normalize the tumor microenvironment and improve cancer treatments. The study showed that this approach can help correct abnormalities that protect tumors and improve blood vessel function and immune activation within a tumor.
SourceMassachusetts General Hospital·JournalJournal of Controlled Release·TypeExperimental study·DateMar 11, 2022
Researchers from H. Lee Moffitt Cancer Center identified unique features of acral melanoma, including immune checkpoints that could represent novel therapeutic targets for this neglected disease. The study's findings may lead to more effective treatments for patients with acral melanoma.
SourceH. Lee Moffitt Cancer Center & Research Institute·JournalClinical Cancer Research·TypeExperimental study·DateMar 11, 2022
Researchers at Okayama University have developed a novel 'green' synthesis technique for the production of NEt-3IB, a promising small-molecule oral drug candidate for inflammatory bowel disease (IBD). The new method produces large quantities of NEt-3IB with high purity and a total yield of over 30%, using only recoverable organic solve...
SourceOkayama University·JournalChemical and Pharmaceutical Bulletin·TypeCommentary/editorial·DateMar 11, 2022
Cavefish have evolved remarkable physiology to cope with a low-oxygen environment, including producing more hemoglobin through larger red blood cells. This adaptation allows them to forage longer in the caves, where food is limited, and may provide insights into how animals evolve elevated hemoglobin capacity.
SourceUniversity of Cincinnati·JournalScientific Reports·TypeExperimental study·DateMar 11, 2022
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Predatory academic practices are rising globally, with over 80% of researchers indicating they have used problematic outlets. The IAP report recommends training, responsible publishing policies, and transparency in peer-review systems to combat these practices.
SourceThe InterAcademy Partnership (IAP)·TypeLiterature review·DateMar 11, 2022
During the COVID-19 pandemic, Medicaid patients in Wisconsin with opioid use disorder experienced decreased access to treatment, including buprenorphine and urine drug testing. The study highlights the need for continued support and resources for these individuals.
SourceJAMA Network·JournalJAMA Health Forum·DateMar 11, 2022
Research suggests exercise can break the vicious cycle of inflammation that leads to diabetes and depression in people with Long COVID. A 30-minute session of moderate-intensity exercise, such as walking, can be beneficial.
SourcePennington Biomedical Research Center·JournalExercise and Sport Sciences Reviews·TypeLiterature review·DateMar 11, 2022
A study of California state prison staff found that COVID-19 vaccination rates were lower among workers compared to incarcerated individuals, resulting in increased risks of further outbreaks. The plateaued vaccination rates posed significant concerns for continued transmission from prisons to surrounding communities.
SourceJAMA Network·JournalJAMA Health Forum·DateMar 11, 2022
Researchers have developed a new approach to studying brain activity, allowing for longer-term studies and improved understanding of neural traffic jams. The new cranial window system uses surgical glue and a tiny glass window to capture high-quality blood flow imaging and stable electrical recordings.
SourceGeorgia Institute of Technology·JournalScientific Reports·TypeExperimental study·DateMar 11, 2022
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers identified a critical region of CmMYB1 and the CmNDB1 protein that negatively regulate nitrate assimilation genes under nitrogen-repleted conditions. This study provides valuable insights into molecular functions and mechanisms in plants, shedding light on the regulation of transcription under specific nitrogen levels.
SourceTokyo Institute of Technology·JournalFrontiers in Plant Science·TypeExperimental study·DateMar 11, 2022
A new study reveals a significant increase in digital screen time among children during the pandemic, posing risks to their physical health. The excessive screen time is linked to eye strain, unstable vision, dry eyes, and increased risk of obesity.
SourceAnglia Ruskin University·JournalJournal of School Health·TypeLiterature review·DateMar 11, 2022
The Kwong Lab has developed a system of synthetic biosensors that can quickly assess the effectiveness of cancer treatment using non-invasive urinalysis. The sensors detect the presence of immune cells and tumor proteases, allowing for timely feedback on treatment response.
SourceGeorgia Institute of Technology·JournalNature Biomedical Engineering·TypeExperimental study·DateMar 11, 2022
Scientists have developed a new model to simulate the formation of subduction zones, which are crucial for understanding Earth's global dynamics. The model predicts the initiation of self-replicating subduction zones and their potential impact on earthquake risk.
SourceFaculty of Sciences of the University of Lisbon·JournalCommunications Earth & Environment·DateMar 11, 2022
A clinical trial conducted by RCSI researchers found that administering alpha-1 antitrypsin to critically ill COVID-19 patients reduced inflammation after one week. The study's results are promising and may form the basis for a larger trial.
SourceRCSI·JournalMed·TypeRandomized controlled/clinical trial·DateMar 11, 2022
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers at UCI have made a breakthrough in understanding the Taq enzyme, which is crucial for DNA sequencing. They found that Taq behaves unexpectedly, rejecting correct bases more frequently than expected. This discovery has significant implications for personalized medicine and the accuracy of sequenced genomes.
SourceUniversity of California - Irvine·JournalScience Advances·TypeExperimental study·DateMar 11, 2022
Researchers at the University of Bath have developed a new coating method for soft robots that allows them to change shape and movement through human-controlled activity. This breakthrough in active matter could lead to the creation of machines governed by individual units that cooperate to determine movement and function.
SourceUniversity of Bath·JournalScience Advances·TypeExperimental study·DateMar 11, 2022
A mathematical analysis suggests that crossing a climate tipping point can lead to minor, stepwise changes in large, heterogeneous systems, rather than irreversible disasters. This finding challenges the widely-held assumption that tipping points always result in catastrophic consequences.
SourceUniversity of Copenhagen - Faculty of Science·JournalEnvironmental Research Letters·TypeComputational simulation/modeling·DateMar 11, 2022
A project in East St. Louis, Illinois is using a public health model to deploy effective interventions for medically and socially vulnerable residents to obtain COVID-19 testing, treatment, and vaccination services. Critical dialogues are being used to engage participants in discussions about their beliefs on preventive behaviors.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·DateMar 11, 2022
A new study led by Phil Crews at UC Santa Cruz identifies a method to measure smoke-derived compounds directly, providing practical guidelines for winemakers. The analysis of over 200 samples found that two biomarkers were not useful and recommended replacing them with different ones.
SourceUniversity of California - Santa Cruz·JournalJournal of Natural Products·DateMar 11, 2022
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A team of scientists led by Karine Le Roch has identified two proteins, RAP01 and RAP21, crucial to the malaria parasite's survival. Knocking down these proteins can interrupt protein translation in the mitochondria, leading to the parasite's death.
SourceUniversity of California - Riverside·JournalNature Communications·TypeExperimental study·DateMar 11, 2022
Researchers at Texas Biomedical Research Institute have found that adding an antibody to the widely-used TB vaccine significantly improves its long-term effectiveness. The combination of the vaccine and an IL-10 blocker allows for better control of TB infection in mice, with improved lung health and increased memory immune cells.
SourceTexas Biomedical Research Institute·JournalThe Journal of Immunology·DateMar 11, 2022
Researchers identified key differences in metabolic processes between brain and spinal cord oligodendrocytes, which could lead to new therapeutic treatments for neurodegenerative diseases. The study also found that targeting a specific cell protein may enhance cholesterol and myelin production.
SourceRutgers University·JournalCell Reports·TypeObservational study·DateMar 11, 2022
Researchers from the University of Tsukuba found that D-serine controls tissue pocket formation, allowing for successful tail regression in marine sea squirts. The study's findings provide insight into epidermal homeostasis and evolutionary perspectives on D-amino acid function.
SourceUniversity of Tsukuba·JournalScience Advances·DateMar 11, 2022
Physicists create cold molecular ions using a new method and detect ultracold molecules with high sensitivity. The technique uses a single trapped ion to sense tiny amounts of molecules, opening up new possibilities for precision spectroscopy and understanding ultracold collisions.
SourceUniversiteit van Amsterdam·JournalPhysical Review Letters·DateMar 11, 2022
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Researchers sequenced bacteria associated with Fucus vesiculosus, finding tissue-specific bacteria important for alga's health. The study revealed new insights into the relationships between marine bacteria and algae, shedding light on the impact of climate change on ecosystem services.
Physicists simulate acoustic propulsion of freely orientable nanoparticles by traveling ultrasound waves, finding that particle orientation affects propulsion. The study reveals important properties of acoustically propelled nanoparticles suitable for biomedical applications.
SourceUniversity of Münster·JournalACS Nano·TypeComputational simulation/modeling·DateMar 11, 2022
A new study calls on tour operators to mitigate the cost of their staff's emotional labor, arguing changes would be easy and quick. The tourism industry relies heavily on recruiting extroverts to work as resort reps, but even they need support to maintain a façade of happiness.
SourceUniversity of Portsmouth·JournalTourism Management·DateMar 11, 2022
Researchers from the Netherlands Institute for Neuroscience have published a dataset of electrophysiology data recorded from two monkeys' visual cortex during resting state. The dataset provides high-density receptive field coverage and can be used to yield new insights into background activity influencing visual information processing.
SourceNetherlands Institute for Neuroscience - KNAW·JournalScientific Data·DateMar 11, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers from HKUMed found that pet Syrian hamsters acquired SARS-CoV-2 infection and transmitted it to humans, resulting in sustained transmission. The study highlights the need for systematic surveillance of SARS-CoV-2 in animals.
SourceThe University of Hong Kong·JournalThe Lancet·DateMar 11, 2022
A global study found symptoms of COVID-19 differ significantly between countries and individuals with underlying health conditions. Researchers analyzed data from 78,299 individuals in 190 countries, revealing varied symptom profiles that can inform clinical practice, public health messaging, and treatment strategies.
SourceImperial College London·JournalEClinicalMedicine·DateMar 11, 2022
A new study from Rice University finds that two-thirds of Muslims, half of Jews and more than a third of evangelical Protestant Christians experience workplace discrimination in different ways. Muslims and Jews feel targeted by anti-Islamic and antisemitic rhetoric, while Christians are perceived as judgmental for taking moral stances.
SourceRice University·JournalSocius Sociological Research for a Dynamic World·TypeObservational study·DateMar 11, 2022
Treatment with an antibody to repulsive guidance molecule-a (RGMa) prevents disease-associated signaling processes and reduces symptoms of neuromyelitis optica in rats. This discovery suggests that anti-RGMa antibodies may represent an effective therapeutic strategy for NMO-associated neuropathic pain and motor deficits.
SourceOsaka University·JournalAnnals of Neurology·TypeExperimental study·DateMar 11, 2022
Researchers develop NAnocrystalling Transport path in Ultrathin dielectrics for REinforcing passivating contact to overcome surface passivation and conductivity tradeoffs. The new contact consists of three-layer structures made up of silicon nanoparticles sandwiched between two layers of oxygen-rich SiOx.
SourceNagoya University·JournalACS Applied Nano Materials·TypeExperimental study·DateMar 11, 2022
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A new early screening tool for autism has been found to be extremely accurate in identifying young children on the autism spectrum. The tool, developed by La Trobe University researchers, detects over 3 years earlier than traditional testing and has already been used in 11 countries.
SourceTania Ewing and Associates·JournalJAMA Network Open·TypeExperimental study·DateMar 11, 2022
A study by CSIC researchers has discovered and synthesized molecules that inhibit the effect of heparin, a widely used anticoagulant drug. The molecules have been tested in mice with excellent results, showing potential as antidotes for heparin reversal drugs.
SourceSpanish National Research Council (CSIC)·JournalJournal of Medicinal Chemistry·TypeExperimental study·DateMar 11, 2022
A new study examines the impact of COVID-19 and George Floyd's death on police work in Tempe, Arizona. The study found that the pandemic had a larger impact on policing and crime than Floyd's death, with varying effects by type of crime.
SourceCrime and Justice Research Alliance·JournalJustice Quarterly·DateMar 11, 2022
A study led by Frank Keppler and Ilka Bischofs reveals that all organisms release methane, with the process driven by reactive oxygen species. The researchers verified this finding in over 30 model organisms, including bacteria, archaea, yeasts, plant cells, and human cell lines.
SourceMax-Planck-Gesellschaft·JournalNature·TypeExperimental study·DateMar 11, 2022
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Aled Edwards emphasizes the importance of basic and applied research in developing effective COVID-19 vaccines. He also stresses the need for better vaccination implementation, increased global access to vaccines, and a cultural shift towards viewing access to new medicines as a right rather than an asset.
SourceUniversity of Toronto·JournalScience·TypeCommentary/editorial·DateMar 11, 2022
AAVMC awards Dr. Barry T. Rouse with the Excellence in Research Award for his outstanding contributions to viral immunology and immunopathology research. With over $20 million in NIH funding, he has published more than 425 papers and mentored almost 80 post-doctoral fellows.
SourceUniversity of Tennessee Institute of Agriculture·DateMar 11, 2022
Researchers from Purdue University and other institutions have discovered a supermassive black hole binary system, consisting of two black holes that orbit each other. The system is significant due to its close separation, which may lead to a merger releasing massive energy in gravitational waves.
SourcePurdue University·JournalThe Astrophysical Journal·DateMar 11, 2022
Researchers have identified a novel material with long coherence lifetimes, enabling the storage and processing of quantum states. The discovery paves the way for quantum information processing and has potential applications in quantum computing, simulation, and secure communication.
SourceKarlsruher Institut für Technologie (KIT)·JournalNature·DateMar 11, 2022
A bi-national regulation targeting ships entering the Great Lakes since mid-2000s has reduced invasive species risk by 85%, with a significant impact on fisheries and biodiversity. The study suggests that saltwater flushing through ballast tanks is a crucial control strategy.
SourceMcGill University·JournalConservation Letters·DateMar 11, 2022
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
Researchers at UC San Diego have discovered a novel molecular process in corals that controls the subcellular environment of symbiotic algae. The study provides new understanding of the ecologically important animal-microbe relationship, with potential implications for coral health and disease.
SourceUniversity of California - San Diego·JournalScience Advances·TypeObservational study·DateMar 11, 2022
Research team finds mutations leading to omicron variant don't affect immune response in people with pre-existing immunity. This suggests individuals who were previously infected or vaccinated may still be protected against breakthrough infections, but humoral immunity may fail.
Researchers at MIT have developed a new system that can automatically clean solar panels without using water, reducing dust accumulation's impact on efficiency. The system uses electrostatic repulsion to detach dust particles, improving overall power output and potentially saving $200,000 in annual revenue.
SourceMassachusetts Institute of Technology·JournalScience Advances·DateMar 11, 2022
Researchers found that social media consumers trust verified accounts less than unverified ones if the content is inconsistent with the influencer's brand. Verified accounts can actually harm trust and may not be more effective at selling products.
SourceUniversity of Maine·JournalJournal of Consumer Behaviour·DateMar 11, 2022
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers found that tree spacing can control the likelihood of tree survival and reduce forest damage risk. Trees in forests with closer spacing are more vulnerable to strong winds due to reduced energy transfer buffering between trees.
SourceShinshu University·JournalScience Advances·TypeData/statistical analysis·DateMar 11, 2022
A team of researchers created a theoretical model demonstrating the difference in electrical differential capacitance between polymeric and ordinary ionic liquids. They predict a huge increase in capacitance for polymeric ionic liquids compared to regular ionic liquids with the same chemical composition.
SourceNational Research University Higher School of Economics·JournalPhysical Chemistry Chemical Physics·DateMar 11, 2022
Researchers developed a simple, inexpensive test to detect organophosphate pesticides directly in foods and biological samples. The method uses a new enzymatic cascade reaction called HELP to synthesize luciferin analogues, which produce luminescence in different wavelengths.
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateMar 11, 2022
Researchers at Brookhaven Lab propose a cosmological phase transition as the key to supermassive black hole formation in the early universe. This process, facilitated by ultralight dark matter particles, enabled efficient collapse of matter into black holes.
SourceDOE/Brookhaven National Laboratory·JournalPhysical Review Letters·DateMar 11, 2022
A new discovery could lead to modified thiazolidinediones with fewer side effects, benefiting more patients with diabetes. Activating only PPARγ2 eliminates the risk of weight gain while maintaining anti-diabetic effects.
SourceUniversity of Pennsylvania School of Medicine·JournalGenes & Development·TypeRandomized controlled/clinical trial·DateMar 11, 2022
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
New study suggests surface minerals of outer main-belt asteroids, which are thought to be the source of Earth's water and life, are only stable at low temperatures. This proposal indicates that these asteroids formed in distant orbits and differentiated into different minerals in their mantles and cores.
SourceTokyo Institute of Technology·JournalAGU Advances·TypeObservational study·DateMar 11, 2022
A recent study confirms that tuberculosis strains associated with marine mammals were also present in inland populations in pre-colonial South America. The researchers found three new ancient TB genomes from human remains in the highlands of Colombia, which resemble a TB variant found in seals and sea lions.
SourceUniversity of Oklahoma·JournalNature Communications·DateMar 11, 2022
Researchers found that disruption of normal neuronal functions affects metabolic activity, potentially contributing to drug-seeking behaviors. The study suggests that alterations in dopamine signaling may reprogram the circadian liver metabolome, leading to substance use disorders.
SourceUniversity of California - Irvine·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateMar 11, 2022
The study found that nearly half of older adults in the US have poor diet quality, with overall diet quality worsening over the past two decades. Diet quality is a significant concern for this age group, as it can impact their health and well-being.
SourceJAMA Network·JournalJAMA Network Open·DateMar 11, 2022
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Researchers at RCSI University of Medicine and Health Sciences have discovered that platelets can form a provisional fibronectin matrix, similar to fibroblasts, which has potential implications for maintaining blood clot integrity during vascular repair. This finding challenges existing paradigms in wound healing.
Elite-level athletes face significant risks and challenges in eating disorder care, with up to 45% of female athletes and 19% of male athletes affected. Treatment must consider the athlete's sport context, including the role of coaches, sports psychologists, and teammates.
SourceWolters Kluwer Health·JournalCurrent Sports Medicine Reports·DateMar 11, 2022
A new study by Bigelow Laboratory for Ocean Sciences reveals that microbial life in the ocean is adapting to warmer conditions, maintaining vital processes despite climate change. The research found that carbon export was maintained as phytoplankton populations declined due to other small organisms taking up the slack.
SourceBigelow Laboratory for Ocean Sciences·JournalNature Communications·DateMar 11, 2022
Researchers found that voles in Inner Mongolia, China, trim tall grasses when shrikes are nearby, decreasing predation risk. The voles' behavior is an example of ecosystem engineering, where they modify their environment to improve survival.
SourceUniversity of Exeter·JournalCurrent Biology·TypeObservational study·DateMar 11, 2022
A WVU postdoctoral researcher has made a groundbreaking discovery in the field of magnetic reconnection, which can be used to predict space weather events that affect satellite and power grid systems. The study uses advanced laser diagnostics to measure electron speeds, providing new insights into plasma physics processes.
SourceWest Virginia University·JournalPhysical Review Letters·DateMar 11, 2022
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers found a new form of ant society that emerged in one species and then spread to other species through hybridization. This allowed the ants to outcompete single-queen colonies and become more successful.
SourceQueen Mary University of London·JournalNature Communications·DateMar 11, 2022
Scientists have successfully modified red blood cells to transport viral agents that trigger the immune system against SARS-CoV-2. The new method, described in PLOS ONE, shows promise as a safe and effective vaccine delivery platform with potential for rapid adaptation to emerging variants.
SourceMcMaster University·JournalPLOS ONE·TypeExperimental study·DateMar 11, 2022
Researchers at MIT and University of London found that collective electric fields produced by neurons provide a stable and consistent signal of information in working memory. This allows the brain to function even if individual neurons die or change.
SourcePicower Institute at MIT·JournalNeuroImage·TypeExperimental study·DateMar 11, 2022