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Science News for April 5, 2022


The dark matter of the brain

Electrical synapses play a vital role in brain function and stability, influencing individual nerve cell activity. In Drosophila, researchers found electrical synapses occur in almost all brain areas, affecting visual processing and neuron stability.

SourceMax-Planck-Gesellschaft·JournalCurrent Biology·DateApr 5, 2022

Sick patients get cosmetic surgery to look healthier

Patients with serious illnesses seek cosmetic procedures to maintain their physical and mental well-being, as well as to become comfortable in social settings. The study found that these procedures are often chosen for noninvasive treatments and endorsed by doctors, friends, and family.

SourceNorthwestern University·JournalJournal of the American Academy of Dermatology·TypeCase study·DateApr 5, 2022

HIV drug stabilizes disease progression in metastatic colorectal cancer

A clinical trial reveals that lamivudine, a widely used HIV treatment, halted disease progression in 28% of patients with fourth-line metastatic colorectal cancer. The study suggests an unexpected promising direction for cancer treatment and encourages the exploration of pairing reverse transcriptase inhibitor therapy with immunotherapy.

SourceMassachusetts General Hospital·JournalCancer Discovery·TypeRandomized controlled/clinical trial·DateApr 5, 2022

Both antibiotic resistant bacteria and genes transmitted between healthy dogs and cats and their owners, finds study in UK and Portugal

Researchers found that healthy companion animals and their owners can transmit antibiotic-resistant bacteria and genes to each other, highlighting the importance of hygiene practices around pets. The study suggests that even low-level shedding of bacteria by healthy carriers can pose a risk to vulnerable individuals.

Innovation flows across regions and sectors in complex ways, study shows

A new study analyzes knowledge transfers across 853 US counties in five manufacturing industries, revealing the importance of local environment, university research, and industry structure for innovation. The findings provide insights into inter- and intra-regional flows, as well as the role of external factors in knowledge output.

SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalSpatial Economic Analysis·TypeData/statistical analysis·DateApr 5, 2022

Study: Carbs, sugary foods may influence poor oral health

A recent study has found a link between high carbohydrate intake and the diversity of oral bacteria in postmenopausal women. The researchers also discovered associations between sugar consumption and certain types of gum disease, such as gingivitis. These findings suggest that diet may play a role in the development of periodontal dise...

SourceUniversity at Buffalo·JournalScientific Reports·TypeObservational study·DateApr 5, 2022

U.S. trees may provide over $100 billion dollars in savings via environmental benefits – but face growing threats

A recent study found that US trees generate a total of $114 billion annually in ecosystem services, with carbon storage and air quality regulation contributing 51% and 37% respectively. The most valuable tree species are pine and oak, but face growing threats from climate change and pests.

SourcePLOS·JournalPLOS Sustainability and Transformation·TypeObservational study·DateApr 5, 2022

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

Researchers have discovered 15 genomic loci that either accelerate or decelerate brain aging, offering potential new drug targets to combat Alzheimer's disease and other degenerative brain disorders. The study, led by USC researchers, found overlap with genes involved in depression, schizophrenia, and cognitive functioning.

SourceUniversity of Southern California·JournalNature Neuroscience·TypeData/statistical analysis·DateApr 5, 2022

Is digital health just for the rich?

The review highlights the importance of regulatory frameworks, equity, ethics, accountability, and governance in digital health initiatives. The future of digital health in LMICs may be tied to securing public-private partnerships to address concerns around data safety, confidentiality, and access.

SourceAnnual Reviews·JournalAnnual Review of Public Health·TypeLiterature review·DateApr 5, 2022

Study reveals how deadly tick disease spreads

A new study analyzed brown dog ticks, canine and human infections, and climatic data to understand how Rocky Mountain spotted fever spreads. The research found that the vectoring capacity of the brown dog tick may be spreading outside its known region, putting a larger portion of the country at risk.

Tiny jumping genes fingered as culprit in rise of antibiotic resistance

Biomedical engineers at Duke University have discovered a physical mechanism that causes high doses of antibiotics to promote the spread of antibiotic resistance between bacteria. The culprit is an overabundance of 'jumping genes,' called transposons, which carry genetic instructions for resistance from cell's source code to plasmids.

SourceDuke University·JournalNature Ecology & Evolution·TypeExperimental study·DateApr 5, 2022

Molecules produced by cells in response to stress may be indicators of various diseases

Researchers at Massachusetts General Hospital have discovered that certain RNA molecules called tDRs released by cells in response to stress can serve as markers of cellular stress in different diseases. The study created an atlas of stress signatures for tDRs, which can be used to diagnose and understand various conditions.

SourceMassachusetts General Hospital·JournalAdvanced Science·TypeExperimental study·DateApr 5, 2022

How left brain asymmetry is related to reading ability

A new study reveals that greater left-brain asymmetry is related to both better and average performance on reading ability tests, depending on the analysis method used. The findings support two opposing theories of language processing, suggesting a complex relationship between brain structure and speech sound processing.

SourcePLOS·JournalPLOS Biology·TypeObservational study·DateApr 5, 2022

Fresh take on cool plasma

Australian and Asian researchers have used a simulation of a new experimental technique to determine accurate electron cross-sections in liquid using a micro-jet of water, paving the way for more efficient plasma-liquid models. This proof-of-concept model uses machine learning and Monte Carlo training data to enhance predictive power.

SourceFlinders University·JournalInternational Journal of Molecular Sciences·TypeExperimental study·DateApr 5, 2022

SwRI scientists connect the dots between Galilean moon, auroral emissions on Jupiter

SwRI scientists studied particle population and auroral emissions on Jupiter, confirming a decade-old theory that electrons accelerated in both directions create the multi-spot dance of auroral footprints. The research also provided insights into the interaction between Ganymede's magnetic field and Jupiter's massive magnetosphere.

SourceSouthwest Research Institute·JournalGeophysical Research Letters·DateApr 5, 2022

Reproductive factors and dementia risk

A study published in PLOS Medicine found that certain reproductive events, such as shorter estrogen exposure, may be associated with increased dementia risk in women. However, the association between the number of children and dementia risk was similar for women and men, suggesting social and behavioral factors may play a role.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateApr 5, 2022

The pleasant smell of wet soil indicates danger to bacteria-eating worms, Concordia researchers find

A study published in Applied and Environmental Microbiology reveals that geosmin, a common soil contaminant, acts as an aposematic signal to deter bacteria-eating worms like C. elegans from poisonous microbes. The researchers found that geosmin triggers the worm's sense of taste, warning it of potential danger.

SourceConcordia University·JournalApplied and Environmental Microbiology·TypeObservational study·DateApr 5, 2022

The recovery process after a heart attack

A recent study published in Molecular Therapy Nucleic Acids found that the molecule urocortin-2 may regulate recovery processes after a heart attack by modulating miR-29a. Treatment with urocortin-2 could favor patient recovery by regulating apoptosis and fibrosis.

SourceUniversity of Seville·JournalMolecular Therapy — Nucleic Acids·DateApr 5, 2022

Emergency caesarean placenta response

A new study finds that emergency Caesarean sections are associated with increased inflammation in the placenta, which may compromise a baby's long-term health and development. The research also reveals sex differences in inflammatory gene expression between male and female babies born via C-section versus vaginal delivery.

SourceFlinders University·JournalFrontiers in Immunology·TypeSurvey·DateApr 5, 2022

Alpha brain waves can predict post-surgery pain

A new technique developed at the University of Birmingham uses electroencephalography (EEG) to measure brain activity in patients before surgery, predicting their likelihood of severe pain after recovery. This allows clinicians to plan additional preventative pain medication and potentially reduce chronic symptoms.

SourceUniversity of Birmingham·JournalBritish Journal of Anaesthesia·TypeExperimental study·DateApr 5, 2022

Shedding new light on controlling material properties

Researchers at Kyoto University have discovered a scaling law that determines high-order harmonic generation in the perovskite material Ca2RuO4. The phenomenon, which was first observed in atomic gas systems, has been found to be highly dependent on temperature and gap energy.

SourceKyoto University·JournalPhysical Review Letters·TypeExperimental study·DateApr 5, 2022

People with epilepsy live shorter lives

A Danish cohort study reveals people with epilepsy die significantly earlier than the general population, with excess mortality pronounced among those with mental disorders. The study's findings have important implications for healthcare professionals and highlight the need for targeted preventive efforts to reduce mortality.

SourceAarhus University·JournalBrain·TypeRandomized controlled/clinical trial·DateApr 5, 2022

Houston Methodist researchers identify an immunotherapy target to combat glioblastomas

Glioblastomas, the deadliest brain cancer, have evaded immune cells by promoting immunosuppressive myeloid cells. Researchers identified S100A4 as a key molecule that can selectively target these immune suppressive cells. This discovery paves the way for new therapeutic strategies to restore antitumor action in glioblastoma patients.

SourceHouston Methodist·JournalNature Communications·TypeExperimental study·DateApr 5, 2022

Towards sustainable, self-powered energy devices with coconuts

Researchers have developed high-performance energy storage and harvesting devices using coconut husk biowaste, achieving 16-fold higher voltage generation and 12-fold higher current generation compared to conventional devices. The devices also show potential for monitoring human breathing patterns in real-time.

SourceDGIST (Daegu Gyeongbuk Institute of Science and Technology)·JournalSustainable Materials and Technologies·TypeExperimental study·DateApr 5, 2022

Primary care medical home found to be more effective than usual care in treating patients with serious mental illness

A new study by UCLA researchers found that a specialized primary care medical home improved the care and treatment of patients with serious mental illness, resulting in better mental health-related quality of life. The patient-centered medical home model provided comprehensive, coordinated care among patients and their clinicians, lead...

SourceUniversity of California - Los Angeles Health Sciences·JournalJournal of General Internal Medicine·TypeRandomized controlled/clinical trial·DateApr 5, 2022

Rational neural network advances machine-human discovery

A novel 'rational' neural network reveals underlying mathematical equations through Green's functions, enabling humans to understand machine-generated findings. This breakthrough in partial differential equation learning holds promise for advancing scientific exploration of weather systems, climate change, and more.

SourceCornell University·JournalScientific Reports·DateApr 5, 2022

New metric more accurately evaluates physician performance

A new approach for measuring physician adherence to best practices has been developed, taking into consideration patient characteristics and physician training background. The study found that pulmonary and critical care medicine training was associated with higher recognition of ARDS, a form of lung failure.

SourceNorthwestern University·JournalBMC Medical Research Methodology·TypeData/statistical analysis·DateApr 5, 2022

Research discovery a pearl of hope for imperiled oyster reefs

A 15-year study by University of Virginia researchers shows that restored oyster reefs can match natural reef populations in about six years and continue to thrive thereafter. The study's findings suggest that restoration can catalyze rapid recovery of imperiled coastal habitats and help reverse decades of degradation.

SourceUniversity of Virginia·JournalConservation Letters·TypeExperimental study·DateApr 5, 2022

NTU Singapore scientists develop a recyclable pollen-based paper for repeated printing and ‘unprinting’

Researchers at Nanyang Technological University in Singapore have developed a sustainable, pollen-based 'paper' that can be printed on and reused multiple times. The paper's non-toxic properties make it an attractive alternative to conventional wood-based paper, which has a significant environmental impact.

SourceNanyang Technological University·JournalAdvanced Materials·DateApr 5, 2022

Bees win in survival wars

Researchers found that social bee parasites and their host species have similar rates of evolution, contrary to predictions. This unexpected finding suggests that smaller population sizes may not hinder a parasite's ability to adapt and survive.

SourceFlinders University·JournalEcology and Evolution·TypeObservational study·DateApr 5, 2022

Dental anomalies among childhood cancer survivors differ according to type of anticancer treatment received

A study found that childhood cancer survivors who received combined chemotherapy and radiotherapy have a higher risk of dental developmental anomalies. The first signs of dental disturbances can appear within one or two years after treatment. Researchers identified specific treatments and age factors associated with increased DDA risk.

SourceThe Hebrew University of Jerusalem·JournalScientific Reports·TypeData/statistical analysis·DateApr 5, 2022

Treated plastic waste good at grabbing carbon dioxide

Researchers at Rice University have developed a method to turn treated plastic waste into an effective carbon dioxide sorbent, capable of removing CO2 from flue gas streams. The process involves heating plastic waste in the presence of potassium acetate, producing particles with nanometer-scale pores that trap CO2 molecules.

SourceRice University·JournalACS Nano·TypeExperimental study·DateApr 5, 2022

Fitness needs the right timing

The study found that cryptochromes are conserved across various green organisms, influencing cell structures responsible for photosynthesis. The researchers discovered that a specific cryptochrome can actually lead to increased growth despite appearing darker green due to denser packed cell membranes.

SourceFriedrich-Schiller-Universitaet Jena·JournalPLANT PHYSIOLOGY·DateApr 5, 2022

Global team of scientists determine ‘fingerprint’ for how much heat, drought is too much for forests

A global team of scientists has identified a consistent pattern of hotter-drought conditions leading to forest mortality events. The study reveals that limiting Earth's warming will determine the survivability of many forests, with higher temperatures projected to double tree-killing droughts.

SourceUniversity of Florida·JournalNature Communications·TypeData/statistical analysis·DateApr 5, 2022

Vitamin K shows evidence of brain benefits in rats

A new study found that vitamin K2 supplementation improved spatial memory, learning ability, and reduced evidence of cognitive impairment, depression, and anxiety in rats. The researchers suggest that vitamin K may help preserve cognitive functions by affecting biological pathways involving inflammation and antioxidant activity.

How to track a shark

A massive dataset reveals complex ecological relationships between sharks and game fish, offering a clearer understanding of their interactions. The study's innovative use of acoustic telemetry and machine learning helps inform fisheries management strategies to protect both species.

SourceUniversity of Massachusetts Amherst·JournalEcological Applications·DateApr 5, 2022

Researchers discover bacteria capable of killing fungus that causes yield-reducing disease in sugarcane

Researchers have discovered three strains of Pseudomonas bacteria that can inhibit and even kill the fungus responsible for pineapple sett rot, a disease that affects sugarcane yields. The study found that these bacteria produce volatile organic compounds that downregulate genes essential to fungal growth, leading to cell death.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalEnvironmental Microbiology·DateApr 5, 2022

Researchers at the GIST identify new medicines using interpretable deep learning predictions

A new deep learning-based model called Highlights on Target Sequences (HoTS) predicts binding between drugs and target molecules, providing interpretable results. The model can predict target proteins' binding regions and interactions with drugs without a 3D complex.

SourceGIST (Gwangju Institute of Science and Technology)·JournalJournal of Cheminformatics·TypeComputational simulation/modeling·DateApr 5, 2022

Solar cell keeps working long after sun sets

Researchers developed a photovoltaic cell that harnesses energy from temperature differences between the cell and surrounding air, generating 50 milliwatts per square meter at night. The device avoids need for batteries and can be incorporated into existing solar cells, making it suitable for remote locations with limited resources.

SourceAmerican Institute of Physics·JournalApplied Physics Letters·DateApr 5, 2022

Decoding the molecular clock that controls neurogenesis in the visual center of Drosophila

In a study published in Nature Communications, researchers uncovered the molecular players involved and how timing is controlled for creating neural diversity. Single-cell RNA sequencing technology revealed a temporal patterning gene network in Drosophila medulla neuroblasts, including nine new transcription factors.

Late-onset alcohol abuse can be a presenting symptom of dementia, researchers find

Research finds that late-onset alcohol abuse may be a presenting symptom of dementia, particularly in patients with frontotemporal dementia. The study identified that up to 7% of patients with frontotemporal dementia started abusing alcohol late in life, and 5% did so as the first symptom of the disease.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJournal of Alzheimer’s Disease·TypeData/statistical analysis·DateApr 5, 2022

New UCI-led study lays foundation for establishing base editing as a one-time, durable treatment for inherited retinal degeneration

A new UCI-led study indicates base editing has tremendous potential to treat inherited retinal degeneration, particularly in Leber congenital amaurosis (LCA) patients. The treatment rescued cone photoreceptors on a long-term basis, suggesting a one-time, durable treatment for LCA patients.

SourceUniversity of California - Irvine·JournalNature Communications·DateApr 5, 2022

New link between greenhouse gasses and sea level rise

A new study provides evidence that long-term warming of the Amundsen Sea, a key contributor to global sea level rise, is linked to rising greenhouse gases. The research suggests that ocean temperatures in the region have been rising since before records began and are expected to continue if greenhouse gas emissions increase.

SourceBritish Antarctic Survey·JournalGeophysical Research Letters·DateApr 5, 2022

‘Robot scientist’ Eve finds that less than one third of scientific results are reproducible

A study using AI-powered robot scientist Eve analyzed over 12,000 research papers on breast cancer cell biology and found that less than one third of the results were reproducible. The researchers found that significant evidence for repeatability was found in 43 papers, while 22 papers showed replicable results under different conditions.

SourceUniversity of Cambridge·JournalJournal of The Royal Society Interface·DateApr 5, 2022

Are strokes a social justice issue? A new study suggests they could be

A new study published in the Journal of the American Medical Association found that non-white Americans and those with lower socioeconomic status are more likely to have severe strokes, long-term disability, and shorter life expectancy compared to their white counterparts. The study suggests that hospitals may be disincentivized to tre...

SourceNorthern Arizona University·JournalJournal of the American Medical Association·DateApr 5, 2022

Effective mRNA protection by poly(l-ornithine) synergizes with endosomal escape functionality of a charge-conversion polymer toward maximizing mRNA introduction efficiency

Researchers have developed a novel nanocarrier system that synergizes poly(l-ornithine) for mRNA protection with charge-conversion polymer for endosomal escape. This innovation enhances protein expression efficiency by approximately 80-fold, outperforming traditional PLL-based systems.

SourceInnovation Center of NanoMedicine·JournalMacromolecular Rapid Communications·TypeExperimental study·DateApr 5, 2022

With a whiff ‘e-nose’ can sense fine whisky

A new e-nose prototype, NOS.E, can distinguish between six whiskies by brand names, regions, and styles in under four minutes, with 100% accuracy for region detection and 96.15% for brand name identification. The technology has applications beyond whisky, including counterfeiting detection in perfume and wine.

SourceUniversity of Technology Sydney·JournalIEEE Sensors Journal·TypeExperimental study·DateApr 5, 2022

BU study: racial disparities in child exposure to gun violence worsened

A new study found that non-White children experienced greater exposure to neighborhood firearm violence before the pandemic and saw an increase in disparities during COVID. The study quantified racial disparities in childhood exposure to gun violence with data from every US neighborhood.

SourceBoston University School of Public Health·JournalAmerican Journal of Preventive Medicine·TypeData/statistical analysis·DateApr 5, 2022

Chatbots deployed in response to COVID-19 pandemic

Researchers analyzed 61 COVID-specific chatbots in 30 countries, finding common uses such as risk assessment, symptom data collection, and appointment scheduling. They also discovered that anonymity of user interactions varies across cultures, affecting the effectiveness of follow-up services.

SourceUniversity of Georgia·JournalJournal of the American Medical Informatics Association·DateApr 5, 2022