A longer reproductive period and use of hormone replacement therapy during menopause were associated with lower small-vessel disease burden in the brain. Women who had used both hormone replacement therapy and the contraceptive pill showed the most favorable profile for their vascular brain health.
A large, long-term study of over 52,000 women aged 45-59 found that contemporary hormone replacement therapy is not associated with an increased risk of heart attack, stroke, blood clots, or premature death. The study suggests that women starting hormone therapy around the time of menopause may not face significant cardiovascular risks.
A systematic review of five studies found no statistically significant improvements in cognitive function among women taking testosterone during menopause. The authors suggest further research is needed to guide treatment decisions and support women in making informed choices about their care.
A new study by Bournemouth University reveals that autistic people experience more severe menopausal symptoms, leading to poorer wellbeing and quality of life. The study found stark health inequalities, including higher rates of anxiety, depression, and physical illness among autistic participants.
The American Heart Association, along with three medical societies, has created a landmark publication redefining heart health in girls and women. The new framework connects women's heart health to distinct life stages, enabling earlier identification of cardiovascular risk and personalized prevention.
A landmark series of publications explores connections among hormonal changes, mental health, and cardiovascular health, offering a unified approach to cardiovascular concerns specifically for women across distinct life stages. Each stage offers 'windows of opportunity' to prevent heart disease, from adolescence to old age.
Researchers discovered that postmenopausal ovaries continue to remodel with age, exhibiting increased inflammation and tissue structural changes. This finding challenges the notion that the ovary is an inactive organ after menopause, suggesting a potential link between ovarian aging and chronic diseases.
Researchers found abrupt changes in bodily health and function across 52 lab tests, including bone health, liver and kidney function, and cholesterol levels. The study identified accelerating changes in sex hormone levels more than a decade before menopause, suggesting a potential window for preventive care.
During menopause, women are at greater risk for heart disease and stroke, making it crucial to focus on health before and during the transition. Healthcare professionals recommend discussing concerns with a healthcare team and taking proactive steps to protect cardiovascular health.
A study published in Menopause Journal found that physical activity, such as walking and yoga, can reduce depressive symptoms and improve quality of life during menopause. The review of 12 randomized controlled trials revealed that aerobic-based exercise and mind-body activities had strong effects on psychological symptoms.
The American College of Physicians recommends estrogen therapy as the first-line treatment for perimenopausal and postmenopausal women experiencing menopausal vasomotor symptoms, which include hot flashes and night sweats. For women without a uterus, estrogen monotherapy is also a viable option.
A new scale for reproductive aging in Chinese women has been developed based on ultra-sensitive AMH testing. The scale provides age-specific percentiles for AMH levels in women aged 35-55, enabling earlier identification of women at risk of low ovarian reserve and better management of perimenopausal symptoms.
A new post-hoc analysis of the ATTAIN-1 and -2 studies found significant and similar weight reductions for women of different menopausal status, with up to 14% body weight loss and 12.5cm waist circumference reduction
Researchers developed a safer alternative to traditional hormone replacement therapy, targeting only one estrogen receptor to promote metabolic protection and prevent tumor growth. The approach restored metabolic balance, improved liver function, and reduced risk of diseases like diabetes and high cholesterol.
A large Danish study found that current use of oral menopausal hormone therapy is associated with an increased risk of blood clots in legs/lungs, with no general increased risk seen with transdermal hormone therapy. Stroke and heart attack risks were limited to prolonged high-dose oral hormone therapy.
Researchers analyzed data from the Framingham Heart Study to investigate the relationship between menopause and aortic stiffness. The study found that factors other than menopause timing contributed to the increase in pulse pressure in women after midlife.
A study of nearly 400,000 women found menopause is inconsistently documented in electronic health records, with only 7% of women having it recorded. The study highlights the need for routine capture of reproductive health information to improve understanding of menopause and its impact on disease risk and health outcomes.
A US study of 20 years of health data found that hormone therapy initiated during peri- or early postmenopause reduces cardiovascular disease risk by 22% compared to those who did not use hormone therapy. The protective effect was strongest among Black women and those who initiated therapy within 10 years of menopause onset.
A study found that CADD522 strengthened bones in post-menopausal mice while reducing body fat and reversing metabolic changes linked to menopause. The treatment also appeared to reverse menopause-related changes in fatty acids and lipid abnormalities.
A new study suggests that estrogen hormone treatment combining estriol and progesterone may help alleviate 'brain fog' symptoms in menopausal women. The study found significant reductions in cognitive symptoms such as memory, concentration, and problem-solving after 12 months of treatment.
Researchers found that aerobic exercise significantly improves executive functions, including planning, task-switching, and focus, in post-menopausal women. Regular exercise can help preserve cognitive health and reduce the risk of Alzheimer's disease, with benefits observed as early as three months into the program.
A new study published in the Journal of the COPD Foundation suggests that women with a shorter reproductive lifespan are at greater risk of developing bronchiectasis. The study of nearly 97,000 postmenopausal women found that hormone therapy use was associated with a 19% greater risk of bronchiectasis.
A large UK study found that hormone replacement therapy (HRT) may reduce the risk of dementia, particularly for women who have undergone surgical menopause. The study, which followed over 180,000 postmenopausal women, found that HRT was associated with a 16% lower risk of developing Alzheimer's disease compared to non-users.
A new hypothesis proposes that women's reproductive resilience is key to understanding longevity, with menopause representing an important inflection point in the loss of reproductive resilience. This framework challenges traditional views on aging and fertility, highlighting the importance of studying women in longevity research.
A long-term study of 1,200 women in eastern Massachusetts found that those living in disadvantaged neighborhoods faced faster declines in heart health and worse cardiovascular risk before menopause. The research highlights the importance of addressing socioeconomic factors in preventing heart disease.
A new study reveals that menopause symptoms such as cognitive impairment and emotional wellbeing are more commonly discussed on Reddit than in clinical records. The study highlights the importance of online forums in capturing stigmatized or poorly understood conditions like perimenopause and menopause.
AI model improves cardiac MRI interpretation, while immersive VR simulators aid poststroke rehabilitation. Meanwhile, menopause tracking apps offer empowerment but also pose risks due to inaccurate information and targeted marketing.
Researchers at CU Anschutz have developed a promising nonhormonal therapy for women experiencing Genitourinary Syndrome of Menopause (GSM), which affects the vulva, vagina, and urinary tract. The therapy restores estrogen signaling in vaginal tissue without exposing the rest of the body to estrogen.
A pooled data analysis of 44 countries reveals that early menopause is more prevalent in rural areas, but education and delayed childbearing minimize the risk. The overall prevalence was 7% among women aged 30-49, with the highest rates found in Ethiopia, Indonesia, and Myanmar.
The first real-world study of fezolinetant found the treatment improved hot flashes, depression, and anxiety in women with menopausal vasomotor symptoms. In a study of 656 women, fezolinetant significantly reduced hot flash symptoms and showed benefits similar to those seen in clinical trials.
A retrospective cohort study found that menopausal hormone therapy significantly reduces the risk of low bone mineral density by 69% compared to non-users. This suggests that hormone therapy could be an effective way to prevent bone loss and lower fracture risks in women after menopause.
A new study published in Menopause journal found that replacing animal protein with plant-based sources like soybeans, beans, and grains leads to significant weight loss in postmenopausal women. The study's lead author suggests that the quality of protein, not just quantity, plays a key role in weight regulation and metabolic health.
A 20-year study in the UK, Australia, and US reveals a significant increase in menopause-related search patterns focused on commercial products and services. This shift indicates a growing need for non-clinical guidance and support beyond traditional clinical encounters.
A recent study found that hormone therapy use among US women has steadily declined from 4.4% in 2007 to 1.7% in 2023, despite its proven benefits for symptom relief and quality of life. The majority of women who could benefit from hormone therapy are not receiving it due to misconceptions about risks and limited training among clinicians.
A study found that 14 million workdays are lost annually due to menopause, while women rely on online misinformation for medical advice. The authors advocate for open conversation and inclusive approaches to combat stigma and support women's health during this transition.
The Mount Sinai Health System has opened the Carolyn Rowan Center for Women’s Health and Wellness, which brings together multidisciplinary clinical expertise, structured care pathways, and leading-edge research to deliver personalized, comprehensive care for women. The Center offers guided multi-visit experiences and coordinated care o...
A large study of nearly 40,000 women found that plant-based diets with lower insulinemic potential can help women manage their weight and reduce the risk of obesity during menopause. Women who followed a diet rich in whole grains, nuts, legumes, and vegetables had a significantly lower risk of developing obesity.
A new preclinical study finds that estrogen loss in the extracellular matrix of the hippocampus may contribute to memory decline and increased risk of Alzheimer's disease in postmenopausal women. The study suggests a possible new treatment approach focused on restoring the brain's supportive environment.
A report by the European Society of Cardiology advocates for dedicated women's heart centers to improve diagnosis and treatment of cardiovascular disease in women. These centers can enhance quality of life, reduce symptoms, and increase survival rates for women with cardiovascular disease.
Polyendocrine Ovarian Syndrome (PMOS) impacts 13% of women, causing hormonal imbalance, insulin resistance, and chronic pain. Lifestyle interventions, particularly diet and exercise, show benefits for physical and mental health outcomes.
NUTRITION 2026 will feature new, unpublished research findings relevant to consumer choices, clinical practice and public policy. The meeting is the premier place to dig deep into the discourse on what we eat and why it matters.
The ECE 2026 brings together researchers and clinicians to share the latest endocrine research and developments. Key sessions include Plenaries, Symposia, Awards, Meet the Experts, Debates, and Oral Communications.
Researchers have created a new scale to measure whether lactating mothers' psychological needs are being met, providing a tool to improve breastfeeding outcomes. The study found that when all three basic needs (autonomy, competence, and relatedness) are satisfied, exclusive breastfeeding is more likely to persist.
Dr. Hannah Cabré has been appointed as an Assistant Professor and Director of the Aging, Gynecology, and Endocrinology Laboratory at Pennington Biomedical Research Center. Her research focuses on the role of female sex hormones in shaping nutrition, health, and performance across the lifespan.
A new study reveals that menopause causes profound and uneven transformations across the female reproductive system, rather than a uniform decline. The research identified molecular signals associated with aging detectable in blood, allowing for non-invasive monitoring and earlier detection of risks.
A study published in Cells suggests that declining estrogen levels alter epigenetics, which may explain the rise in heart disease risk after menopause. The researchers identify a potential link between estrogen loss and changes in cardiovascular health.
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
Replacing meat and dairy with plant-based foods reduces greenhouse gas emissions by 35%, equivalent to eliminating 600 miles of driving. A low-fat vegan diet with soybeans also produces major health improvements, including a 92% reduction in severe hot flashes.
A new study from Tulane University found that women with high predicted cardiovascular risk face nearly double the risk of hip fracture. The association was stronger in women under 65, and higher cardiovascular risk was linked to fractures in weakened bones in major areas.
Researchers from the University of Waterloo have identified the key factor behind estrogen's protective effects against high blood pressure, finding vasodilation to be the crucial mechanism. This discovery holds promise for more effective treatment options for women after menopause, when estrogen levels naturally decline.
The Alliance for Clinical Trials in Oncology will host a webinar highlighting recent clinical advances in breast cancer, multiple myeloma, and leukemia. Researchers will present key findings from ASH and SABCS meetings, impacting treatment outcomes.
A new collaborative clinician education program will equip cardiologists and OB-GYNs with practical tools to identify and treat cardiovascular risk in midlife women. The program aims to close treatment gaps and provide proactive, integrated care during menopause.
A large Danish study found that menopausal hormone therapy is not associated with an increased risk of death in women with moderate to severe symptoms and no contraindications. The study also showed a significant survival benefit for women who had undergone bilateral oophorectomy after using hormone therapy.
A nationwide Finnish registry-based study found no increased risk of pre- or postmenopausal breast cancer among women with a history of induced abortion or miscarriage. Breast cancer risks were similar regardless of the number of abortions or miscarriages, as well as the time of first abortion or miscarriage.
A global study of 17,494 people from 158 countries reveals a significant gap between expected and experienced perimenopause symptoms. Fatigue, mood changes, and sleep-related issues are the most common reported symptoms, with exhaustion and fatigue being particularly prevalent.
A study from the University of Cambridge found that menopause is associated with reduced grey matter volume in key brain regions, increased anxiety and depression, and difficulties with sleep. Despite hormone replacement therapy (HRT) not mitigating these effects, it can slow reaction times.
A new study from the University of Victoria found that higher insulin levels at age 47 predicted younger onsets of hot flashes and night sweats. Insulin may be a stronger predictor of hot flashes when taking other metabolic variables into account, while body mass index (BMI) appeared more closely associated with estrogen level changes.
Research by Bournemouth University explores the impact of menopause on autistic people, finding that symptoms can be disabling and life-threatening. The study highlights the need for better support and resources to help neurodivergent individuals navigate this transition.
The Global Centre for Asian Women’s Health has partnered with NUS Medicine to host the Women’s Health Impact Tracking (WHIT) platform, which measures progress on closing the women’s health gap across a set of conditions and countries. The platform provides clear, comparative insights to support decision-making and inform policies.
A comprehensive review of prior research found no evidence that menopause hormone therapy increases or decreases dementia risk in post-menopausal women. The study included data from over 1 million participants and analyzed the impact on mild cognitive impairment and Alzheimer's disease, with no significant association found.