Key target for rejuvenation treatments needs ‘re-brand’
Recent research reveals that targeting senescent cells as the cause of aging is not accurate. Instead, these cells have positive health impacts and may pose risks if targeted therapeutically.
Wound Healing
Articles tagged with Wound Healing
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New “smart bandages” hold potential for revolutionizing the treatment of chronic wounds
Researchers are developing advanced electronic bandages to improve chronic wound monitoring and healing. These 'smart' dressings can sense and respond to changing conditions, providing continuous data on healing and potential complications.
Exploration of enzyme-polymer interactions is a crucial first step toward the development of next-gen degradable wound coverings
Scientists aim to create a spray-on bandage that breaks down within 48 hours, providing time for proper treatment. The project uses enzymes to degrade polymer complexes, which will allow for controlled degradation and potential applications in drug delivery.
Personalized phage therapy heals resistant wounds-squeaks makes full recovery
A new study demonstrates personalized phage therapy's effectiveness in treating antibiotic-resistant infections in animals, with a case of a cat healing from a persistent wound. The treatment combines a specific anti-Pseudomonas aeruginosa phage with ceftazidime, achieving full healing after 14 weeks.
Acute pseudoaneurysms following head gunshot wounds
A new study reveals that traumatic intracranial aneurysms are more common and associated with intracerebral hematomas after civilian gunshot wounds, challenging conventional wisdom. Spontaneous resolution occurs in approximately 40% of patients.
Zoology: First report of wound treatment by a wild animal using a medicinal plant
A Sumatran orangutan observed applying chewed Akar Kuning leaves to a facial wound, leading researchers to investigate the plant's potential healing properties. Rakus' treatment of his own injury may indicate an intentional behavior shared with humans and great apes.
Orangutan treats wound with pain-relieving plant
A male Sumatran orangutan applied sap from a climbing plant with anti-inflammatory and pain-relieving properties to a facial wound, closing it within five days. This self-medication behavior may have originated in a common ancestor shared by humans and orangutans.
Medical school scientist creates therapy to kill hypervirulent bacteria
A new therapy has been identified that can penetrate the slime protecting drug-resistant bacteria, allowing it to be killed by the body's immune system or antibiotics. The antimicrobial peptide, derived from cow peptides, targets sugar connections in the slime structure, damaging its integrity and allowing entry.
It takes two to TANGO: New strategy to tackle fibrosis and scarring
Researchers developed a new experimental strategy to tackle scarring and fibrosis by releasing enough collagen to prevent tissue damage while protecting it from excessive amounts. The strategy, which uses molecules known as peptides to block the export of collagen from cells, shows promise in treating conditions such as scleroderma.
Wound treatment gel fights the battle against antibacterial resistance
Researchers created a hydrogel that kills bacteria naturally, promotes cell growth and heals wounds more effectively than traditional gels. The gel is infused with amino acid polylysine and platelet-rich blood plasma to create properties well-suited for wound care.
Healing eyes with contact lenses
Researchers at the University of Waterloo have developed a patented contact lens material that acts as a bandage for corneal wounds, releasing drugs in a controlled manner to enhance healing. The material, which uses collagen-based technology, achieves complete wound healing within five days in human cell culture studies.
Brigham researchers develop sprayable hydrogel for gastrointestinal wound healing
Researchers at Brigham and Women's Hospital developed a sprayable adhesive hydrogel product to address GI wound management limitations. The material promotes rapid wound healing, provides tissue protection, and minimizes complications under harsh conditions.
Revolutionary chronic wound treatment could help millions
A team of international scientists has developed an effective treatment for preventing infection in chronic wounds that does not involve antibiotics. The new method involves the plasma activation of hydrogel dressings, producing a unique mix of chemical oxidants that are effective in decontaminating and aiding healing.
A sprayable gel could make minimally invasive surgeries simpler and safer
Researchers at MIT developed GastroShield, a sprayable gel that prevents bleeding and leakage from weakened gastrointestinal tissues during endoscopic procedures. The gel forms a protective layer that reinforces tissue integrity and promotes healing.
Lab-spun sponges form perfect scaffolds for growing skin cells to heal wounds
Scientists from the University of Surrey have developed a technique for electrospinning 3D scaffolds, allowing skin grafts to be grown directly from a patient's own skin. The scaffolds showed improved viability and functionality compared to traditional methods.
NIH grant to aid Rumbaugh’s biofilm dispersal research
Rumbaugh's lab aims to understand the effects of dispersing bacteria from a biofilm on their susceptibility to antibiotics and on the host. They will use enzymes as tools to break up biofilms, allowing researchers to better comprehend the relationship between bacterial dispersal and infection outcomes.
A new glue, potentially also for you
Researchers create a simple method to instantly bond layers made of the same or different types of hydrogels using a thin film of chitosan. The new approach has potential to broadly advance new biomaterials solutions for multiple unmet clinical needs, including regenerative medicine and surgical care.
Giant step forward to help treat chronic wounds that affect millions
A team of scientists has developed a new treatment for chronic wounds that uses ionized gas plasma to decontaminate and heal wounds. The technology shows promise in treating diabetic foot ulcers, internal wounds, and potentially cancerous tumours.
Nanofiber bandages fight infection, speed healing
Researchers at Cornell University have developed nanofiber-coated cotton bandages that exhibit excellent antibacterial performance against gram-negative and gram-positive bacterial species. The bandages, infused with lawsone, a red-orange compound found in henna leaves, also show antioxidant and anti-inflammatory properties.
Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring
Researchers discovered that microRNA-29 can restore normal skin structure rather than producing a scar, promoting faster and more efficient wound healing. The release of microRNA-29 targets, particularly LAMC2, is crucial in this process, suggesting a potential new approach for treating large-area or deep wounds.
CityU neuroscientists uncover the therapeutic potential of low-dose ionizing radiation for traumatic brain injury and ischemic stroke
Researchers found that low-dose X-ray irradiation reduced lesion size and reversed motor deficits in TBI and ischemic stroke mice, demonstrating its potential as a therapeutic strategy. The treatment also accelerated substantial motor function recovery and promoted brain rewiring after stroke.
Perceived time has an actual effect on physical healing
New Harvard study finds that perceived time influences actual physical healing time, challenging conventional beliefs about psychological influence on health. The study used a standardized procedure to mildly wound volunteer subjects and found that wounds healed faster when participants believed more time had passed.
Ants recognize infected wounds and treat them with antibiotics
Matabele ants can recognize infected wounds and effectively treat them with their own produced antibiotics, drastically reducing mortality. The ants' sophisticated healthcare system has medical implications for humans, as the primary pathogen in ant wounds is also a leading cause of infection in humans.
Revolutionary seaweed and carbonated water based hydrogel for treating skin wounds
Researchers from Tokyo University of Science developed a novel, low-cost hydrogel using seaweed extract that prevents wound expansion and promotes healing. The hydrogel demonstrates significantly lower adhesion and swelling compared to conventional hydrogels, making it an excellent alternative for treating skin wounds.
Chronic wounds a significant health and economic burden—costing Singapore $350 million annually
Chronic wounds in Singapore result in a significant economic burden of SGD$350 million each year. The study found that hospital admissions and decline in quality of life contribute to these costs.
Incheon National University scientists develop new hydrogels for wound management
Researchers from Incheon National University create gelatin patches that generate molecular oxygen to accelerate wound healing. The new hydrogels demonstrate improved coagulation, blood closure, and neovascularization in both in vitro and in vivo experiments.
Looking sharp! Shark skin is unique and may have medical use, too
Researchers studied shark and skate skin mucus to understand its unique biochemistry. They found a thin, neutral mucus layer with properties similar to human mucus, suggesting potential biomedical applications for wound care and treatment.
Plasma technology transforms microalgae for faster wound healing
Researchers at Flinders University use plasma technology to transform Spirulina microalgae into ultrathin bioactive coatings that accelerate healing, modulate inflammation, and protect against infection. The new technique could be a game-changer for wound healing around the world.
New wound healing research by Wake Forest Institute for Regenerative Medicine produces full thickness human bioprinted skin
Researchers at Wake Forest Institute for Regenerative Medicine successfully created full thickness human bioprinted skin, promoting quicker healing and more naturally appearing outcomes. The bioprinted skin facilitated human-like skin architecture in vivo, with improved wound closure, reduced scarring, and enhanced tissue formation.
Ultrathin nanotech promises to help tackle antibiotic resistance
Researchers at RMIT University have developed a nano-thin superbug-slaying material effective against drug-resistant bacterial cells. The black phosphorus-based nanotechnology achieved comparable results to antibiotics in eliminating infection and accelerating healing.
Study sheds light on why wounds often heal poorly in diabetics
Defective exosomes in diabetic patients drive inflammation and impair wound healing. Researchers identified alterations in exosome cargo and release that compromise wound healing in diabetes. New exosome-focused therapies may promote healing of chronic wounds.
Breakthrough in scarless wound recovery achieved with autologous blood
Researchers at UNIST developed a microfluidic system to process blood into artificial tissue scaffolds for vascular regeneration. Autologous blood-based implants demonstrated superior wound closure rates, increased epidermis thickness, and enhanced collagen deposition in rodent skin wounds.
New pocket-sized device for clinicians could spot infected wounds faster
A new pocket-sized device uses heat signatures and bacterial fluorescence to identify infected wounds, providing a more accurate diagnosis than traditional methods. The device achieved an overall accuracy of 74% in identifying different categories of wounds, with 100% accuracy in distinguishing between infected and non-infected wounds.
Study examines struggles of Haitian migrants self-managing diabetes on Dominican Republic sugar cane fields
A new study from the University of Missouri found that poverty, low health literacy, cultural beliefs, lack of infrastructure, and political issues hinder diabetes self-management for Haitian migrants. The researchers suggest targeted interventions, such as community gardens and healthcare education through local priests.
Protein found in milk speeds up wound healing
A new study published in Interface found that casein, a protein found in cow's milk, significantly improved wound healing in rats compared to control groups. The promising results suggest that casein could replace expensive materials like silver in wound dressings.
Study identifies how diabetes slows healing in the eye
Researchers at Cedars-Sinai have identified two disease-associated changes to the cornea in diabetes patients that delay wound healing. The study proposes three therapeutic pathways that reversed these changes and partially restored wound-healing function, offering new potential treatments for diabetes.
Historical medicine suggests a new way to use modern treatments
Researchers discovered that combining honey and vinegar can effectively kill bacteria in biofilms, making it a potential treatment for persistent infections. The study found that using both honey and acetic acid was more effective than using either substance alone.
All-in-one device for hemorrhage control
A new device combines rapid hemorrhage management, infection control, and sensing capabilities for long-term monitoring. The device features a tunable biodegradation rate and can detect bleeding in real-time using a nanowire-based capacitive sensor.
Nottingham expert works on new project to reduce post-c-section infections in Brazil
A Nottingham University Business School expert is working with Brazilian nurses to reduce post-caesarean wound infections, a common issue worldwide. The project aims to prevent infections through improved care management, which could improve quality of life and reduce healthcare costs.
Curettage and cryosurgery – effective for the most common skin cancer
A study published in the Journal of the American Academy of Dermatology found that curettage and cryosurgery is an effective and safe treatment method for basal cell carcinoma. The procedure involves scraping the lesion with a curette followed by freezing, resulting in good outcomes with minimal side effects.
Innovative paper-like, battery-free, AI-enabled sensor for holistic wound monitoring
The PETAL sensor patch measures five biomarkers to assess wound inflammation and infection, providing timely medical intervention. It is a low-cost, versatile, and customizable solution for holistic wound monitoring.
Chronic wound healing using glass
Bioactive glasses with ionic silver show improved antimicrobial activity and can retain effectiveness against antibiotic-resistant bacteria. The study demonstrates the potential for this combination to deliver more effective wound protection than conventional alternatives.
Programmable 3D printed wound dressing could improve treatment for burn, cancer patients
Researchers created a new type of wound dressing material using advanced polymers, enabling customized dressings with fine-tuned surface adhesion. The material has potential applications in burn treatment and drug delivery for cancer patients, providing constant medication release outside the clinic setting.
PAINTing a wound-healing ink into cuts with a 3D-printing pen
Researchers developed a wound-healing ink that can actively encourage the body to heal by exposing cuts to immune-system vesicles. The PAINT system, which uses EVs secreted from macrophages combined with sodium alginate, promoted blood vessel formation and reduced inflammation in human epithelial cells.
New type of drug candidate effectively accelerates wound healing in clinical study
Researchers at Uppsala University developed a modified lactic acid bacteria treatment that accelerated wound healing in humans. The study showed improved outcomes and safety with ILP100-Topical, a potential new treatment for complex and hard-to-heal wounds.
Study reveals unique molecular machinery of woman who can’t feel pain
Researchers at UCL have uncovered the molecular basis of a woman's rare genetic mutation that allows her to live pain-free and heal rapidly. The study found that the mutation in the FAAH-OUT gene turns down FAAH gene expression, affecting other molecular pathways linked to wound healing and mood.
“Hightech” materials from nature
A research team at Göttingen University has discovered that mobile and stationary cells have different mechanical properties due to their cytoskeleton. The study found that intermediate filaments, which are crucial for cell stability, exhibit metal-like plasticity when stretched, similar to non-biological materials.
Breaking through bacterial barriers in chronic treatment-resistant wounds
Researchers developed a new method combining palmitoleic acid, gentamicin, and non-invasive ultrasound to improve drug delivery in chronic wounds infected with S. aureus. The strategy reduced bacterial burden by 94% and successfully sterilized wounds in diabetic mice.
Investing in safe surgery could cut costs and save lives in LMICs
A new study reveals that Surgical Site Infection (SSI) is a major financial burden on health services in LMICs, with patients experiencing higher costs for postoperative care. Investing in health technologies to reduce SSI could help improve healthcare quality and save lives.
A chronic wound model to investigate skin cellular senescence
A new study presents a chronic wound murine model that characterizes the role of persistent senescent cell accumulation in delayed wound closure. The molecular profiles of senescent cells demonstrate the adverse influence of SASP factors, highlighting a potential root-cause-driven therapeutic strategy.
Two-component system could offer a new way to halt internal bleeding
A two-component system designed by MIT engineers has shown promising results in stopping internal bleeding in mouse models. The system, which mimics the body's natural clotting process, uses a nanoparticle and polymer to recruit platelets and form blood clots at injury sites.
The wound dressing that can reveal infection
Researchers at Linköping University developed a nanocellulose wound dressing that reveals early signs of infection through pH monitoring. This technology can lead to more efficient care and reduce unnecessary antibiotic use.
How electricity can heal wounds three times as fast
A team of researchers has developed a method that uses electric stimulation to accelerate wound healing, making it possible for wounds to heal up to three times faster. The technique involves applying an electric field to damaged skin, which helps guide skin cells in the same direction, promoting faster healing.
Iguana stole my cake! and left behind a nasty surprise
A 3-year-old girl was infected with M. marinum after being bitten by an iguana while on holiday in Costa Rica. The toddler developed a ganglion cyst and eventually responded to treatment with rifampin and clarithromycin.
University Hospitals research published in New England Journal of Medicine shows minimally invasive procedure saves most patients with severe vascular disease from amputation
The PROMISE II clinical trial showed that LimFlow therapy enabled 76% of patients to avoid amputation and experience wound healing. This minimally invasive procedure bypasses blocked arteries in the leg and rushes blood back into the foot through the veins, providing a unique alternative to major amputation.
Surgical sealing made better with robust thermosensitive bioadhesives
Scientists developed an injectable biomaterial with improved adhesion, stretchability, and toughness, making it ideal for surgical wound sealing. The material showed superior adhesive strength, stability, and biocompatibility in physiological conditions.
Scientists see anti-aging potential in an invasive weed
Researchers found that cocklebur fruit extracts encouraged collagen production, sped wound healing, and exerted a protective effect against UVB radiation. However, high doses of the extract can be harmful and further research is needed to determine its safe use in cosmetic applications.
Shining light on aging hearts
A study published in Lasers in Surgery and Medicine suggests that light therapy, known as photobiomodulation (PBM), can improve heart function and reduce the thickness of the cardiac wall in middle-aged mice. The research also found improved neuromuscular coordination and a significant survival rate among mice with severe heart disease.
‘Smart’ bandages monitor wounds and provide targeted treatment
Researchers developed smart bandages that can monitor wound conditions and deliver medication to treat inflammation and infection. The bandages have shown promising results in animal models, offering real-time updates and speed healing of chronic infected wounds.
Transfer-tattoo-like cell-sheet delivery for wounds
A team of researchers developed a transfer-tattoo-like cell sheet that can be directly applied to targeted surfaces, facilitating cutaneous wound healing and promoting skin tissue regeneration. The system leverages natural cell migration between surfaces, eliminating the need for external stimuli and detachment processes.