Articles tagged with Mammalian Signaling
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that maternal iron deficiency can lead to male-to-female sex reversal in mouse embryos due to impaired Sry gene activation. Iron is necessary for KDM3A's enzymatic activity, which removes histone methylation allowing the Sry gene to become active.
Researchers from the University of Konstanz and Max Planck Institute of Animal Behaviour found that meerkats use two different types of vocal interactions to communicate within their groups. Close calls are call-and-response exchanges between animals, while short notes announce 'I am here' but don't necessarily get a direct reply.
Researchers found that intrinsically-photosensitive retinal ganglion cells (ipRGCs) use both microvillous and ciliary signaling mechanisms simultaneously. This discovery reveals a new pathway for transmitting light signals to the brain, which may have ancient origins on the evolutionary scale.
A new study reveals that RANK protein suppression affects mammary gland functionality differently depending on pregnancy experience. In female mice, RANK suppression led to successful lactation only during the second pregnancy, suggesting a 'rescue action' by basal cells.
Male mice exhibit increased stress hormones and decreased pain sensitivity when near pregnant or lactating females, which is linked to a specific olfactory signal. This finding has significant implications for improving experiment reliability and represents a breakthrough in mammalian social signaling.
Scientists at the University of Oxford have developed an 'optomemristor' device that facilitates three-factor learning and emulation of biological computations, making it possible to perform complex machine learning tasks. The device uses both light and electrical signals to interact and consume very little energy.
Researchers at the University of Zurich found that humans respond more quickly and with higher sensitivity to positive screams, which indicate joy, than to negative screams. The study revealed six distinct types of scream calls, including pain, anger, fear, pleasure, sadness, and joy.
A study published in PLOS Biology found that human screams communicate multiple emotions beyond fear, including pain, anger, fear, pleasure, sadness, and joy. Researchers used four experiments to investigate the acoustic diversity of scream calls and found that listeners responded more quickly and accurately to non-alarm screams.
Researchers create a genetic signal-transmission system allowing E. coli and Salmonella Typhimurium bacteria to communicate in the mouse gut, enabling a potential 'synthetic microbiome' with engineered bacteria species. This breakthrough could lead to optimized human health through coordinated bacterial functions.
A team of researchers used machine-learning techniques to reconstruct a short movie of small, randomly moving discs from signals produced by rat retinal neurons. Nonlinear decoding methods outperformed linear decoders in accurately reconstructing the movie.
Researchers at Johns Hopkins Medicine have discovered a complex signaling system that directs nerve cell branching and connectivity, using protein signals like Sema-1a to coordinate axon travel patterns. This study has broad implications for human disease research, particularly in understanding muscle control and nerve disorders.